Andreas Skolarikos

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint Prevention of anemia in patients with solid tumors receiving platinum-based chemotherapy by recombinant human Erythropoietin (rHuEpo): a prospective, open label, randomized trial by the Hellenic Cooperative Oncology Group
    A Bamias
    Oncology Department, Ioannina University Hospital, Ioannina, Greece
    Oncology 64:102-10. 2003
  2. pmc Leukocytoclastic vasculitis after long-term treatment with sunitinib: a case report
    Alexandra Karadimou
    Clinical Therapeutics, University of Athens, Athens, Greece
    Case Rep Oncol 4:385-91. 2011
  3. pmc Immune response in ovarian cancer: how is the immune system involved in prognosis and therapy: potential for treatment utilization
    Nikos G Gavalas
    Department of Clinical Therapeutics, Medical School, University of Athens, Alexandra Hospital, 80 Vasilissis Sofias Avenue, 115 28 Athens, Greece
    Clin Dev Immunol 2010:791603. 2010
  4. pmc VEGF directly suppresses activation of T cells from ascites secondary to ovarian cancer via VEGF receptor type 2
    N G Gavalas
    Department of Clinical Therapeutics, Medical School, University of Athens, Alexandra Hospital, 80 Vas Sofias Avenue, 115 28 Athens, Greece
    Br J Cancer 107:1869-75. 2012
  5. pmc Development and validation of a prognostic model in patients with metastatic renal cell carcinoma treated with sunitinib: a European collaboration
    A Bamias
    Department of Clinical Therapeutics, University of Athens, Athens, Greece
    Br J Cancer 109:332-41. 2013
  6. pmc Angiogenesis-related pathways in the pathogenesis of ovarian cancer
    Nikos G Gavalas
    Department of Clinical Therapeutics, Medical School, University of Athens, Alexandra Hospital, Athens, Greece
    Int J Mol Sci 14:15885-909. 2013
  7. doi request reprint Prospective, open-label, randomized, phase III study of two dose-dense regimens MVAC versus gemcitabine/cisplatin in patients with inoperable, metastatic or relapsed urothelial cancer: a Hellenic Cooperative Oncology Group study (HE 16/03)
    A Bamias
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece
    Ann Oncol 24:1011-7. 2013
  8. doi request reprint Angiogenesis: a promising therapeutic target for ovarian cancer
    A Bamias
    Dept of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Crit Rev Oncol Hematol 84:314-26. 2012
  9. doi request reprint Prognostic evaluation of tumour type and other histopathological characteristics in advanced epithelial ovarian cancer, treated with surgery and paclitaxel/carboplatin chemotherapy: cell type is the most useful prognostic factor
    A Bamias
    Dept of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Eur J Cancer 48:1476-83. 2012
  10. doi request reprint A risk-adapted strategy of adjuvant paclitaxel/carboplatin in early-stage ovarian cancer: time-dependent effect of 4 versus 6 cycles on outcome
    Aristotle Bamias
    Department of Clinical Therapeutics, University of Athens, Athens, Greece
    Oncology 81:365-71. 2011

Detail Information

Publications135 found, 100 shown here

  1. ncbi request reprint Prevention of anemia in patients with solid tumors receiving platinum-based chemotherapy by recombinant human Erythropoietin (rHuEpo): a prospective, open label, randomized trial by the Hellenic Cooperative Oncology Group
    A Bamias
    Oncology Department, Ioannina University Hospital, Ioannina, Greece
    Oncology 64:102-10. 2003
    ..We conducted a randomized, open label study to assess the efficacy of erythropoietin in preventing transfusions and significant anemia (hemoglobin <10 g/dl) in patients with solid tumors receiving platinum-based chemotherapy...
  2. pmc Leukocytoclastic vasculitis after long-term treatment with sunitinib: a case report
    Alexandra Karadimou
    Clinical Therapeutics, University of Athens, Athens, Greece
    Case Rep Oncol 4:385-91. 2011
    ..One year after the diagnosis, the patient is still on this therapy. Oncology providers should be aware of this rare but potentially serious, possible adverse effect of sunitinib...
  3. pmc Immune response in ovarian cancer: how is the immune system involved in prognosis and therapy: potential for treatment utilization
    Nikos G Gavalas
    Department of Clinical Therapeutics, Medical School, University of Athens, Alexandra Hospital, 80 Vasilissis Sofias Avenue, 115 28 Athens, Greece
    Clin Dev Immunol 2010:791603. 2010
    ..This paper examines the recent developments in our understanding of the mechanisms of development of the immune response in ovarian cancer as well as its prognostic significance and the existing experience in clinical studies...
  4. pmc VEGF directly suppresses activation of T cells from ascites secondary to ovarian cancer via VEGF receptor type 2
    N G Gavalas
    Department of Clinical Therapeutics, Medical School, University of Athens, Alexandra Hospital, 80 Vas Sofias Avenue, 115 28 Athens, Greece
    Br J Cancer 107:1869-75. 2012
    ..We sought to investigate the possible direct effect of VEGF on T-cell activation and through which type of VEGF receptor it exerts this effect on cells isolated from ovarian cancer patients' ascites...
  5. pmc Development and validation of a prognostic model in patients with metastatic renal cell carcinoma treated with sunitinib: a European collaboration
    A Bamias
    Department of Clinical Therapeutics, University of Athens, Athens, Greece
    Br J Cancer 109:332-41. 2013
    ..We developed and externally validated a simple model for overall survival (OS) in mRCC. We also studied the recently validated International Database Consortium (IDC) model in our data sets...
  6. pmc Angiogenesis-related pathways in the pathogenesis of ovarian cancer
    Nikos G Gavalas
    Department of Clinical Therapeutics, Medical School, University of Athens, Alexandra Hospital, Athens, Greece
    Int J Mol Sci 14:15885-909. 2013
    ..The pathways involved in angiogenesis and molecules that have been developed in order to combat angiogenesis are described in this paper. ..
  7. doi request reprint Prospective, open-label, randomized, phase III study of two dose-dense regimens MVAC versus gemcitabine/cisplatin in patients with inoperable, metastatic or relapsed urothelial cancer: a Hellenic Cooperative Oncology Group study (HE 16/03)
    A Bamias
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece
    Ann Oncol 24:1011-7. 2013
    ..However, the role of GC intensification has not been studied. We conducted a randomized, phase III study comparing a DD-GC regimen with DD-MVAC in advanced UC...
  8. doi request reprint Angiogenesis: a promising therapeutic target for ovarian cancer
    A Bamias
    Dept of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Crit Rev Oncol Hematol 84:314-26. 2012
    ..Apart from VEGF, PDGF, FGF and angiopoietins present a therapeutic interest. We are reviewing the results of published clinical studies using anti-angiogenic factors in advanced ovarian cancer...
  9. doi request reprint Prognostic evaluation of tumour type and other histopathological characteristics in advanced epithelial ovarian cancer, treated with surgery and paclitaxel/carboplatin chemotherapy: cell type is the most useful prognostic factor
    A Bamias
    Dept of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Eur J Cancer 48:1476-83. 2012
    ..Ovarian carcinomas have been classified into types I and II according to the hypothesised mode of carcinogenesis and molecular characteristics. The prognostic significance of this classification has not been studied...
  10. doi request reprint A risk-adapted strategy of adjuvant paclitaxel/carboplatin in early-stage ovarian cancer: time-dependent effect of 4 versus 6 cycles on outcome
    Aristotle Bamias
    Department of Clinical Therapeutics, University of Athens, Athens, Greece
    Oncology 81:365-71. 2011
    ..We investigated the efficacy of risk-adapted adjuvant paclitaxel/carboplatin chemotherapy in early-stage ovarian carcinoma...
  11. pmc A randomized phase III trial of adjuvant chemotherapy with irinotecan, leucovorin and fluorouracil versus leucovorin and fluorouracil for stage II and III colon cancer: a Hellenic Cooperative Oncology Group study
    Christos A Papadimitriou
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, Greece
    BMC Med 9:10. 2011
    ..In this multicenter adjuvant phase III trial, we evaluated the addition of irinotecan to weekly 5FU plus LV in patients with stage II or III colon cancer...
  12. doi request reprint Prognostic factors for early-stage epithelial ovarian cancer, treated with adjuvant carboplatin/paclitaxel chemotherapy: a single institution experience
    A Bamias
    Department of Clinical Therapeutics, University of Athens, Athens, Greece
    Gynecol Oncol 123:37-42. 2011
    ..Early-stage epithelial ovarian cancer represents a prognostically heterogenous group. We studied prognostic factors in patients treated with adjuvant paclitaxel/carboplatin chemotherapy...
  13. doi request reprint The use of 24-h ambulatory blood pressure monitoring (ABPM) during the first cycle of sunitinib improves the diagnostic accuracy and management of hypertension in patients with advanced renal cancer
    A Bamias
    Department of Clinical Therapeutics, University of Athens, Medical School, Greece
    Eur J Cancer 47:1660-8. 2011
    ....
  14. ncbi request reprint Microvessel density (MVD) and cyclooxygenase-2 (COX-2)/ beta-catenin interaction are associated with relapse in patients with transitional carcinoma receiving adjuvant chemotherapy with paclitaxel/carboplatin: a hellenic cooperative oncology group (HECOG)
    A Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Greece
    Anticancer Res 28:2479-86. 2008
    ..Cycloxygenase (COX)-2 has been associated with proliferation, apoptosis and angiogenesis in urothelial cancer. The prognostic significance of COX-2 in patients who received adjuvant chemotherapy for urothelial cancer was examined...
  15. pmc Four cycles of paclitaxel and carboplatin as adjuvant treatment in early-stage ovarian cancer: a six-year experience of the Hellenic Cooperative Oncology Group
    Aristotle Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    BMC Cancer 6:228. 2006
    ..Surgery can cure a significant percentage of ovarian carcinoma confined to the pelvis. Nevertheless, there is still a 10-50% recurrence rate. We administered paclitaxel/carboplatin as adjuvant treatment in early-stage ovarian carcinoma...
  16. ncbi request reprint Prognostic and predictive factors in patients with androgen-independent prostate cancer treated with docetaxel and estramustine: a single institution experience
    Aristotle Bamias
    Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece
    Eur Urol 53:323-31. 2008
    ..To investigate potential prognostic and predictive factors in patients with androgen-independent prostate cancer (AIPC) treated with docetaxel chemotherapy...
  17. ncbi request reprint Correlation of NK T-like CD3+CD56+ cells and CD4+CD25+(hi) regulatory T cells with VEGF and TNFalpha in ascites from advanced ovarian cancer: Association with platinum resistance and prognosis in patients receiving first-line, platinum-based chemotherapy
    Aristotelis Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Greece
    Gynecol Oncol 108:421-7. 2008
    ..We have investigated the association of cytokines in the ascites from patients with ovarian cancer with these populations, the platinum resistance and the prognosis of these patients...
  18. ncbi request reprint Prognostic factors in patients with colorectal cancer receiving adjuvant chemotherapy or chemoradiotherapy: a pooled analysis of two randomized studies
    Aristotle Bamias
    Dept of Clinical Therapeutics, Medical School, University of Athens, Greece
    Int J Gastrointest Cancer 36:29-38. 2005
    ..We are presenting a pooled analysis of prognostic factors from two randomized studies of adjuvant treatment conducted by the Hellenic Cooperative Oncology Group...
  19. ncbi request reprint Systemic chemotherapy in inoperable or metastatic bladder cancer
    A Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Greece
    Ann Oncol 17:553-61. 2006
    ..The true role of such therapies is currently being evaluated...
  20. ncbi request reprint Neoadjuvant chemotherapy in invasive bladder cancer
    Aristotle Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Haidari, 124 62 Athens, Greece
    Expert Rev Anticancer Ther 5:993-1000. 2005
    ..Finally, issues of improving therapeutic efficacy and directing clinical research are discussed...
  21. pmc Prognostic stratification of patients with advanced renal cell carcinoma treated with sunitinib: comparison with the Memorial Sloan-Kettering prognostic factors model
    Aristotelis Bamias
    Department of Clinical Therapeutics, Athens University, Medical School, Athens, Greece
    BMC Cancer 10:45. 2010
    ..We studied the prognostic significance of baseline characteristics and we compared the risk stratification with the established Memorial Sloan Kettering Cancer Center (MSKCC) model...
  22. doi request reprint Editorial comment on: new treatment approaches for prostate cancer based on peptide analogues
    Aristotelis Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Eur Urol 53:899-900. 2008
  23. ncbi request reprint Two cycles of etoposide/cisplatin cured all patients with stage I testicular seminoma: risk-adapted protocol of the Hellenic Cooperative Oncology Group
    Aristotelis Bamias
    Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece
    Urology 70:1179-83. 2007
    ..Although cure is the rule, relapses still occur, especially in high-risk populations. We report the results of a risk-adapted strategy by the Hellenic Cooperative Oncology Group...
  24. ncbi request reprint The combination of gemcitabine and carboplatin as first-line treatment in patients with advanced urothelial carcinoma. A Phase II study of the Hellenic Cooperative Oncology Group
    Aristotle Bamias
    Department of Clinical Therapeutics, Athens University, School of Medicine, Athens, Greece
    Cancer 106:297-303. 2006
    ..The objective of the current multicenter Phase II study was to evaluate the safety and efficacy of the combination of gemcitabine and carboplatin as first-line treatment in unselected patients with advanced urothelial carcinoma...
  25. ncbi request reprint Intensified bimonthly cisplatin with bolus 5-fluorouracil, continuous 5-fluorouracil and high-dose leucovorin (LV5FU2) in Patients with advanced gastrointestinal carcinomas: a phase I dose-finding and pharmacokinetic study
    Aristotle Bamias
    Oncology Department, Ioannina University Hospital, Ioannina, Greece
    Am J Clin Oncol 27:465-71. 2004
    ..Objective response rate in 23 evaluable patients was 39.2%. The combination of LV5FU2 with bimonthly 90 mg/m2 cisplatin is feasible and active and should be further evaluated in patients with advanced gastric cancer...
  26. ncbi request reprint Significant differences of lymphocytes isolated from ascites of patients with ovarian cancer compared to blood and tumor lymphocytes. Association of CD3+CD56+ cells with platinum resistance
    A Bamias
    Department of Clinical Therapeutics, University of Athens, Greece
    Gynecol Oncol 106:75-81. 2007
    ..We performed a prospective study of T lymphocytes isolated from ascites from patients with ovarian carcinoma and we compared them with the respective populations in blood and tumors...
  27. ncbi request reprint Adjuvant chemotherapy with paclitaxel and carboplatin in patients with advanced carcinoma of the upper urinary tract: a study by the Hellenic Cooperative Oncology Group
    A Bamias
    Department of Clinical TherapeuticsUniversity of Athens, School of Medicine, Athens, Greece
    J Clin Oncol 22:2150-4. 2004
    ..We prospectively studied a cohort of patients who underwent surgery for high-risk carcinoma of the upper urinary tract to assess the feasibility of the combination of paclitaxel and carboplatin as adjuvant treatment...
  28. doi request reprint Mucinous but not clear cell histology is associated with inferior survival in patients with advanced stage ovarian carcinoma treated with platinum-paclitaxel chemotherapy
    Aristotle Bamias
    Department of Therapeutics, University of Athens Medical School, Athens, Greece
    Cancer 116:1462-8. 2010
    ..The authors compared the outcome of these subtypes with that of serous tumors in patients who were treated with combination paclitaxel/platinum at their center...
  29. doi request reprint A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer
    Aristotelis Bamias
    Department of Clinical Therapeutics, University of Athens School of Medicine, Athens, Greece
    Cancer Chemother Pharmacol 65:1009-21. 2010
    ..However, the possibility that a benefit by the addition of RT was not detected due to decreased power of the study should not be excluded...
  30. doi request reprint Biweekly carboplatin/gemcitabine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: report of efficacy, quality of life and geriatric assessment
    Aristotle Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Oncology 73:290-7. 2007
    ..We evaluated safety and efficacy of first-line gemcitabine/carboplatin in unfit-for-cisplatin patients with advanced urothelial carcinoma and the effect on the quality of life and functional status of elderly patients (aged >70)...
  31. ncbi request reprint Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: a multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group
    A Bamias
    Department of Clinical Therapeutics Urology, Hygiene and Epidemiology, University of Athens School of Medicine, Athens, Greece
    J Clin Oncol 22:220-8. 2004
    ..The toxicity of this regimen compared favorably with that reported for MVAC. We thus designed a randomized phase III trial to compare DC with MVAC...
  32. ncbi request reprint Editorial comment on: Impact of multimodal treatment on survival in patients with metastatic urothelial cancer
    Aristotle Bamias
    Department of Clinical Therapeutics, University of Athens, Medical School, Athens, Greece
    Eur Urol 52:1113-4. 2007
  33. ncbi request reprint Phase II study of irinotecan and mitomycin C in 5-fluorouracil-pretreated patients with advanced colorectal and gastric cancer
    A Bamias
    Oncology Dept, Ioannina University Hospital, Ioannina, Greece
    J Chemother 15:275-81. 2003
    ..It may represent an attractive option in patients at high risk for developing specific irinotecan toxicity...
  34. ncbi request reprint Diagnosis and management of hypertension in advanced renal cell carcinoma: prospective evaluation of an algorithm in patients treated with sunitinib
    A Bamias
    Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece
    J Chemother 21:347-50. 2009
    ..The application of such protocols instead of commonly used toxicity criteria should be further validated...
  35. doi request reprint Report of the long-term efficacy of two cycles of adjuvant bleomycin/etoposide/cisplatin in patients with stage I testicular nonseminomatous germ-cell tumors (NSGCT): a risk adapted protocol of the Hellenic Cooperative Oncology Group
    Aristotelis Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Urol Oncol 29:189-93. 2011
    ..Certain factors are used to select patients in high-risk for relapse. We report the outcome and safety of a risk-adapted strategy by the Hellenic Cooperative Oncology Group...
  36. ncbi request reprint Neoadjuvant chemotherapy with docetaxel and cisplatin in patients with high-risk resectable bladder carcinoma: long term results
    A Bamias
    Department of Clinical Therapeutics, University of Athens, School of Medicine, Greece
    Eur Urol 46:344-50; discussion 350-1. 2004
    ..We are reporting the results of a phase II study using this combination as neoadjuvant treatment in patients with muscle invasive bladder cancer...
  37. ncbi request reprint The outcome of elderly patients with advanced urothelial carcinoma after platinum-based combination chemotherapy
    A Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, 31 Komninon Street, Haidari, 12462 Athens, Greece
    Ann Oncol 16:307-13. 2005
    ..We compared the tolerability and efficacy of first-line platinum (cisplatin or carboplatin)-based chemotherapy in elderly patients (> or =70 years) with those in younger patients...
  38. ncbi request reprint Young age is associated with favorable characteristics but is not an independent prognostic factor in patients with epithelial ovarian cancer: a single institution experience
    George Bozas
    Department of Clinical Therapeutics, School of Medicine, University of Athens, Athens, Greece
    Oncology 70:265-72. 2006
    ..The aim of the present study was to investigate the characteristics of ovarian cancer presenting in patients aged < or =40 and assess the prognostic significance of young age...
  39. ncbi request reprint Treatment of ovarian germ cell tumors with a 3-day bleomycin, etoposide, and cisplatin regimen: a prospective multicenter study
    Meletios A Dimopoulos
    Departments of Clinical Therapeutics, Obstetrics and Gynecology, University of Athens School of Medicine, 31 Komninon Street, Haidari 124 62, Athens, Greece
    Gynecol Oncol 95:695-700. 2004
    ..We evaluated the safety and activity of a 3-day modified bleomycin, etoposide, and cisplatinum (mBEP) regimen in patients with OGCT...
  40. ncbi request reprint Biweekly gemcitabine and cisplatin in platinum-resistant/refractory, paclitaxel-pretreated, ovarian and peritoneal carcinoma
    George Bozas
    Department of Clinical Therapeutics, University of Athens, Medical School, 31 Komninon St, Haidari, 12462 Athens, Greece
    Gynecol Oncol 104:580-5. 2007
    ..Synergism between gemcitabine and cisplatin is supported by preclinical and clinical data. The present study explores the efficacy of a biweekly regimen in platinum-resistant/refractory, paclitaxel-pretreated ovarian and peritoneal cancer...
  41. ncbi request reprint Combination of docetaxel, estramustine phosphate, and zoledronic acid in androgen-independent metastatic prostate cancer: efficacy, safety, and clinical benefit assessment
    E Efstathiou
    Department of Clinical Therapeutics, University of Athens School of Medicine, Haidari, Athens, Greece
    Urology 65:126-30. 2005
    ..In an effort to minimize toxicity, we designed an every-2-week docetaxel administration regimen with a 3-day low-dose EMP regimen. Patients with bone metastases also received zoledronic acid...
  42. ncbi request reprint Upper urinary tract transitional cell carcinoma. A 10-year experience
    Athanasios G Papatsoris
    Second Department of Urology School of Medicine, University of Athens, Sismanoglio Hospital, Athens, Greece
    Tumori 94:75-8. 2008
    ..To present our 10-year experience with patients surgically treated for upper urinary tract transitional cell carcinoma...
  43. ncbi request reprint Bcl-2 protein and DNA ploidy in renal cell carcinoma: do they affect patient prognosis?
    Andreas Skolarikos
    First Department of Urology, University of Athens, School of Medicine, Athens, Greece
    Int J Urol 12:563-9. 2005
    ..The aim of the present study was to correlate bcl-2 protein expression and DNA-ploidy status with established prognostic parameters in renal cell carcinoma (RCC) and to examine their impact on disease progression and patient survival...
  44. ncbi request reprint Somatostatin analog lanreotide in the treatment of castration-resistant prostate cancer (CRPC)
    Iraklis C Mitsogiannis
    University of Athens, School of Medicine, 2nd Department of Urology, 5 Proussis Street, 14232 Nea Ionia, Athens, Greece
    Expert Opin Pharmacother 10:493-501. 2009
    ..In view of these promising results, large-scale, randomized, controlled trials are warranted to clearly define the exact role of lanreotide and other somatostatin analogs in the treatment of patients with CRPC...
  45. ncbi request reprint The outcome of patients with advanced pure squamous or mixed squamous and transitional urothelial carcinomas following platinum-based chemotherapy
    Efstathios Kastritis
    Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece
    Anticancer Res 26:3865-9. 2006
    ..In this study the efficacy of platinum-based chemotherapy in patients with pure squamous or mixed carcinomas was retrospectively analysed and compared with that in pure TCCs...
  46. ncbi request reprint The impact of age in the outcome of patients with advanced or recurrent cervical cancer after platinum-based chemotherapy
    E Kastritis
    University of Athens, Department of Clinical Therapeutics, Alexandra Hospital, 31 Komninon St, Haidari, 124 62, Athens, Greece
    Gynecol Oncol 104:372-6. 2007
    ..It is unknown whether these young patients have a poorer outcome compared to older patients or whether elderly patients have inferior outcome than younger patients when treated with combination chemotherapy...
  47. ncbi request reprint Use of nonsteroidal anti-inflammatory drugs after radical retropubic prostatectomy: a prospective, randomized trial
    Evangelos M Mazaris
    2nd Department of Urology, University of Athens, Sismanoglio Hospital, Agia Paraskevi, Athens, Greece
    Urology 72:1293-7. 2008
    ..To assess the efficacy and safety of nonsteroidal anti-inflammatory drugs (NSAIDs) administered after radical retropubic prostatectomy (RRP)...
  48. ncbi request reprint A review on follow-up strategies for renal cell carcinoma after nephrectomy
    Andreas Skolarikos
    Athens Medical School, 2nd Department of Urology, Sismanoglio Hopsital, Athens, Greece
    Eur Urol 51:1490-500; discussion 1501. 2007
    ..To provide a comprehensive review of the evidence supporting the necessity for follow-up after nephrectomy for renal cell carcinoma...
  49. ncbi request reprint Does the management of bladder perforation during transurethral resection of superficial bladder tumors predispose to extravesical tumor recurrence?
    Andreas Skolarikos
    2nd Department of Urology, School of Medicine, University of Athens, Sismanoglio General Hospital Athens, Greece
    J Urol 173:1908-11. 2005
    ..We also defined potential risk factors for extravesical recurrence prospectively giving emphasis to the management of the perforation...
  50. ncbi request reprint Transurethral photoselective vaporization versus transvesical open enucleation for prostatic adenomas >80ml: 12-mo results of a randomized prospective study
    Gerasimos Alivizatos
    Athens Medical School, 2nd Department of Urology, Sismanoglio Hospital, Athens, Greece
    Eur Urol 54:427-37. 2008
    ..To compare the effectiveness and the safety of photoselective vaporization of the prostate (PVP) to open prostatectomy (OP) for the surgical treatment of large prostatic adenomas...
  51. ncbi request reprint Outpatient treatment of low-risk neutropenic fever in cancer patients using oral moxifloxacin
    Georgios Chamilos
    Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece
    Cancer 103:2629-35. 2005
    ..Nevertheless, to the authors' knowledge, the best antibiotic regimen and the feasibility of ambulatory treatment have not been clearly defined...
  52. ncbi request reprint Carboplatin plus gemcitabine in patients with inoperable or metastatic pancreatic cancer: a phase II multicenter study by the Hellenic Cooperative Oncology Group
    N Xiros
    Second Department of Internal Medicine, Propaedeutic and Research Institute, University General Hospital Attikon, University of Athens, Greece
    Ann Oncol 16:773-9. 2005
    ..In the present phase II multicenter study, we assessed the efficacy and tolerability of the combination of gemcitabine and carboplatin in patients with advanced pancreatic cancer...
  53. ncbi request reprint The novel prostate cancer antigen 3 (PCA3) biomarker
    Andreas Bourdoumis
    University Department of Urology, Sismanoglio Hospital, Athens, Greece
    Int Braz J Urol 36:665-8; discussion 669. 2010
    ..Results from relevant clinical studies, comparative with PSA, are warranted in order to confirm the perspective of PCA3 to substitute PSA...
  54. ncbi request reprint Reversibility of renal failure in newly diagnosed multiple myeloma patients treated with high dose dexamethasone-containing regimens and the impact of novel agents
    Efstathios Kastritis
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens, School of Medicine, Athens, Greece
    Haematologica 92:546-9. 2007
    ..046). In conclusion, RF is reversible in the majority of newly diagnosed MM patients treated with high-dose dexamethasone containing regimens. The addition of novel agents induces a more rapid RF reversal...
  55. ncbi request reprint Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors
    Aristotle Bamias
    Department of Clinical Therapeutics, Medical School, University of Athens, Greece
    J Clin Oncol 23:8580-7. 2005
    ..We studied the incidence, characteristics, and risk factors for the development of ONJ among patients treated with bisphosphonates for bone metastases...
  56. doi request reprint Somatic mutations of adenomatous polyposis coli gene and nuclear b-catenin accumulation have prognostic significance in invasive urothelial carcinomas: evidence for Wnt pathway implication
    Efstathios Kastritis
    Department of Clinical Therapeutics, Athens University, School of Medicine, Athens, Greece
    Int J Cancer 124:103-8. 2009
    ..Further study of the role of the Wnt pathway, potential crosstalk with other pathways and potential candidate therapeutic targets in urothelial cancer is needed...
  57. ncbi request reprint A phase II study with CPT-11 plus leucovorin and bolus IV 5-fluorouracil in patients with advanced colorectal carcinoma
    H P Kalofonos
    Hellenic Cooperative Oncology Group HeCoG, Data Office, Athens, Greece
    Cancer Invest 21:855-62. 2003
    ..Further studies are needed to compare the present regimen with higher doses of CPT-11 with LV plus different schedules of 5-FU administration in the treatment of metastatic CRC...
  58. ncbi request reprint Adjuvant chemotherapy with paclitaxel and carboplatin in non-endometrioid carcinoma of the uterus
    G T Bozas
    Department of Clinical Therapeutics, University of Athens, Alexandra Hospital, Greece
    Eur J Gynaecol Oncol 26:627-31. 2005
    ..The aim of this study was to investigate the activity and safety of paclitaxel/carboplatin chemotherapy as the only adjuvant treatment in patients with surgically resected UPSC and UCCC...
  59. doi request reprint Hexaminolevulinate-induced fluorescence versus white light during transurethral resection of noninvasive bladder tumor: does it reduce recurrences?
    Theocharis Karaolides
    Anticancer Hospital Agios Sabas, Athens, Greece
    Urology 80:354-9. 2012
    ..To evaluate the effect of hexaminolevulinate (HAL)-induced fluorescence during resection of noninvasive bladder cancer on tumor recurrence compared with resection under white light...
  60. ncbi request reprint Ultrasound-guided percutaneous nephrostomy performed by urologists: 10-year experience
    Andreas Skolarikos
    Second Department of Urology, University of Athens School of Medicine, Sismanoglio General Hospital, Athens, Greece
    Urology 68:495-9. 2006
    ..To assess the safety, feasibility, and effectiveness of percutaneous nephrostomy tube (PNT) insertion performed solely by a urologist on an outpatient basis. We present our relevant 10-year experience...
  61. ncbi request reprint Diagnostic efficacy of transrectal ultrasound-guided biopsy of the prostatic fossa in patients with rising PSA following radical prostatectomy
    Charalambos Deliveliotis
    2nd Department of Urology, University of Athens Medical School, Sismanoglion Hospital, 4 Monis Petraki Street, 11521, Kolonaki, Athens, Greece
    World J Urol 25:309-13. 2007
    ..TRUS-guided biopsy is an efficient tool in detecting local recurrence after RP and should be offered to all patients with biochemical relapse and absence of metastatic disease irrespective of the level of PSA...
  62. doi request reprint Prostate cancer with metastasis to the omentum and massive ascites: a rare manifestation of a common disease
    Flora Zagouri
    Department of Clinical Therapeutics, Athens University, School of Medicine, Athens, Greece
    Onkologie 32:758-61. 2009
    ..The most common sites of metastasis in prostate cancer include bone and regional lymph nodes followed by lung, liver, and brain. Peritoneal metastasis without skeletal involvement is extremely rare...
  63. ncbi request reprint Unreliable residual volume measurement after increased water load diuresis
    Gerasimos Alivizatos
    Second Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    Int J Urol 11:1078-81. 2004
    ..The aim of the present study was to examine whether increased water load intake prior to ultrasound examination of the lower urinary tract, affects the measurement of postvoid residual urine volume...
  64. doi request reprint Management of advanced bladder cancer in patients with impaired renal function
    Evangelos Bournakis
    Department of Clinical Therapeutics, Medical School, University of Athens, 80 Vasilissis Sofias Ave, Athens, Greece
    Expert Rev Anticancer Ther 11:931-9. 2011
    ..The study of newer targeted therapies in the treatment of bladder cancer is also discussed, as are future perspectives and a five-year view in the treatment of the disease in patients with renal impairment...
  65. ncbi request reprint Randomized multicenter phase II trial of cisplatin and ifosfamide with or without paclitaxel in recurrent or metastatic carcinoma of the uterine cervix: a Hellenic Cooperative Oncology Group (HeCOG) study
    G Mountzios
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, Greece
    Ann Oncol 20:1362-8. 2009
    ....
  66. ncbi request reprint Anthracycline-based adjuvant chemotherapy in early-stage uterine sarcomas: long-term results of a single institution experience
    C A Papadimitriou
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Athens, Greece
    Eur J Gynaecol Oncol 28:109-16. 2007
    ..Uterine sarcomas are rare neoplasms characterized by a high rate of local recurrences and distant metastases. The role of chemotherapy in early-stage completely resected disease remains controversial...
  67. ncbi request reprint Carboplatin hypersensitivity reactions: a single institution experience
    M P Zorzou
    Department of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    J Chemother 17:104-10. 2005
    ..In conclusion, pretreatment with corticosteroids, antihistamines and a slower infusion rate may make re-treatment possible in patients having experienced hypersensitivity to carboplatin...
  68. ncbi request reprint Multicenter phase-II trial of irinotecan plus oxaliplatin [IROX regimen] in patients with poor-prognosis cancer of unknown primary: a hellenic cooperative oncology group study
    E Briasoulis
    Ioannina University Hospital, Ioannina, Greece
    Cancer Chemother Pharmacol 62:277-84. 2008
    ..We evaluated the irinotecan-oxaliplatin combination (IROX regimen) in previously untreated patients with non-favorable subsets of unknown primary carcinomas...
  69. ncbi request reprint Brain metastases as isolated site of relapse in patients with epithelial ovarian cancer previously treated with platinum and paclitaxel-based chemotherapy
    E Kastritis
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Athens, Greece
    Int J Gynecol Cancer 16:994-9. 2006
    ..Patients with isolated brain metastases have comparable survival to patients with relapse outside the CNS, and long-term remission can be achieved in some cases, provided that systemic chemotherapy is added to local treatment...
  70. ncbi request reprint DNA ploidy as a prognostic factor in muscle invasive transitional cell carcinoma of the bladder
    C Deliveliotis
    Department of Urology, Medical School, University of Athens, Athens, Greece
    Urol Res 33:39-43. 2005
    ..The results of this study suggest that DNA ploidy can provide prognostic information on patients with muscle invasive carcinoma of the bladder and might represent a means of selection for postoperative management...
  71. doi request reprint Training in ureteroscopy: a critical appraisal of the literature
    Andreas Skolarikos
    Athens Medical School, Second Department of Urology, Sismanoglio Hospital, Athens, Greece
    BJU Int 108:798-805; discussion 805. 2011
    ..Careful curriculum design in high-volume stone centres may be the key to optimizing URS training...
  72. doi request reprint Prevention and treatment of complications following percutaneous nephrolithotomy
    Andreas Skolarikos
    Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    Curr Opin Urol 18:229-34. 2008
    ..The aim of this article is to identify classification and grading systems of percutaneous nephrolithotomy-related complications and evidence for the prevention and treatment of these complications...
  73. doi request reprint Short- and long-term complications of open radical prostatectomy according to the Clavien classification system
    Constantinos A Constantinides
    1st University Department of Urology, Athens University Medical School, Laiko and Sismanoglio Hospital, Athens, Greece
    BJU Int 103:336-40. 2009
    ..To assess the use of the Clavien classification system in documenting the complications related to open retropubic radical prostatectomy (RRP)...
  74. pmc Bilateral spontaneous retroperitoneal bleeding in a patient on nimesulide: a case report
    Iraklis C Mitsogiannis
    2nd Department of Urology, University of Athens, School of Medicine, Athens, Greece
    J Med Case Rep 5:568. 2011
    ..abstract:..
  75. doi request reprint Problems faced by relatives caring for cancer patients at home
    Thomas Tsigaroppoulos
    2nd Department of Urology, University of Athens, Sismanoglio Hospital, Athens, Greece
    Int J Nurs Pract 15:1-6. 2009
    ..Many of them remain undetected. The acknowledgement and recognition of these problems by health-care professionals might contribute to finding solutions in order to assist the difficult task of these individuals...
  76. doi request reprint Laparoscopic urinary stone surgery: an updated evidence-based review
    Andreas Skolarikos
    Department of Urology, School of Medicine, Sismanoglio Hospital, University of Athens, Athens, Greece
    Urol Res 38:337-44. 2010
    ..Laparoscopic nephrolithotomy may be indicated to remove a stone from an anterior diverticulum or when PNL or flexible ureteroscopy have failed (III/B)...
  77. ncbi request reprint Targeting angiogenesis in renal cell carcinoma
    Georgios Lainakis
    Dept of Clinical Therapeutics, Medical School, University of Athens, 15235 Athens, Greece
    Curr Cancer Drug Targets 8:349-58. 2008
    ..All the agents have been proven more effective than the interferon as first or second-line treatment. This review will focus in these recent developments and the intense continuing clinical research in this field...
  78. doi request reprint VEGF directly suppresses activation of T cells from ovarian cancer patients and healthy individuals via VEGF receptor Type 2
    Apostolos C Ziogas
    Department of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Int J Cancer 130:857-64. 2012
    ..Overall, our study shows that T cells secret VEGF and expresses VEGFR-2 upon activation. VEGF directly suppresses T cell activation via VEGF receptor type 2...
  79. ncbi request reprint The prognostic significance of the immunohistochemical expression of p53, bcl-2, c-erb B-2 and cathepsin-D in ovarian cancer patients receiving platinum with cyclophosphamide or paclitaxel chemotherapy
    A Protopapas
    1st Department of Obstetrics and Gynecology of the University of Athens, School of Medicine, Alexandra Hospital, Athens, Greece
    Eur J Gynaecol Oncol 25:225-9. 2004
    ..To evaluate the prognostic significance of the immunohistochemical expression of p53, bcl-2, c-erbB-2 and cathepsin-D in epithelial ovarian cancer (EOC)...
  80. ncbi request reprint Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group
    P A Kosmidis
    Department of Medical Oncology, Hygeia Hospital, Athens, Greece
    Ann Oncol 19:115-22. 2008
    ..This phase III study was designed to compare the combination paclitaxel (Taxol)-gemcitabine (PG) versus carboplatin-gemcitabine (CG) in patients with advanced inoperable non-small-cell lung cancer...
  81. ncbi request reprint Phase I study of etoposide, cisplatin and irinotecan triplet in patients with advanced-stage small-cell lung cancer
    E Briasoulis
    Medical Oncology Department, University Hospital, Ioannina, Greece
    Cancer Chemother Pharmacol 56:521-8. 2005
    ..The irinotecan-cisplatin combination has emerged as a new standard for the treatment of advanced-stage small-cell lung cancer (AS-SCLC). To move forward we developed a 3-day regimen of cisplatin, etoposide and irinotecan...
  82. doi request reprint Thymidine phosphorylase to dihydropyrimidine dehydrogenase ratio as a predictive factor of response to preoperative chemoradiation with capecitabine in patients with advanced rectal cancer
    C S Boskos
    1st Radiation Oncology Department, Agios Savvas Anticancer Institute, Athens, Greece
    J Surg Oncol 102:408-12. 2010
    ....
  83. doi request reprint Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid
    M A Dimopoulos
    Department of Clinical Therapeutics, Medical School, University of Athens, Greece
    Ann Oncol 20:117-20. 2009
    ..We investigated whether the occurrence of ONJ decreased after the implementation of preventive measures in 128 patients with MM who received zoledronic acid...
  84. ncbi request reprint The outcome of advanced or recurrent non-squamous carcinoma of the uterine cervix after platinum-based combination chemotherapy
    E Kastritis
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University School of Medicine, 31 Komninon Street, Haidari, 124 62 Athens, Greece
    Gynecol Oncol 99:376-82. 2005
    ..We compared the outcome of patients with non-squamous with that of squamous cell carcinomas after platinum-based combination chemotherapy as first line therapy for stage IV or recurrent cervical carcinoma...
  85. ncbi request reprint Adjuvant chemotherapy with paclitaxel and carboplatin in patients with advanced bladder cancer: a study by the Hellenic Cooperative Oncology Group
    A Bamias
    Department of Clinical Therapeutics and Urology, University of Athens, School of Medicine, Greece
    J Urol 171:1467-70. 2004
    ..We report results in a prospective cohort of patients at high risk for relapse who were treated with the combination of paclitaxel and carboplatin as adjuvant treatment following cystectomy for muscle invasive bladder cancer...
  86. ncbi request reprint Sunitinib treatment in patients with severe renal function impairment: a report of four cases by the Hellenic Cooperative Oncology Group
    G Lainakis
    Department of Clinical Therapeutics, University of Athens, Medical School, Athens
    Clin Nephrol 72:73-8. 2009
    ..We conclude that sunitinib can be administered to the majority of patients with RCC and significant renal function impairment...
  87. ncbi request reprint Prognostic factors in patients treated with taxane-based chemotherapy for recurrent or metastatic endometrial cancer: proposal for a new prognostic model
    G Mountzios
    University of Athens, Medical School, Department of Clinical Therapeutics, Athens, Greece
    Gynecol Oncol 108:130-5. 2008
    ..The aim of the study was to determine the prognostic factors in RMEC after taxane-based chemotherapy...
  88. doi request reprint Percutaneous nephrolithotomy in horseshoe kidneys: factors affecting stone-free rate
    Andreas Skolarikos
    Second Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    J Urol 186:1894-8. 2011
    ..We report a 2-center study of factors affecting the stone-free rate after percutaneous nephrolithotomy in horseshoe kidneys...
  89. ncbi request reprint Ureteroscopic removal of mildly migrated stents using local anesthesia only
    Kostantinos E Livadas
    Second Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    J Urol 178:1998-2001. 2007
    ..In the outpatient office setting we evaluated the feasibility and efficacy of ureteroscopic removal of upward migrated ureteral stents using local or no anesthesia...
  90. ncbi request reprint Diagnosis and management of postpercutaneous nephrolithotomy residual stone fragments
    Andreas Skolarikos
    Second Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    J Endourol 23:1751-5. 2009
    ..While medical therapy and shockwave lithotripsy possess a minor role, second-look flexible nephroscopy and/or flexible ureterorenoscopy seem to be the treatments of choice for residual stone fragments after PCNL...
  91. ncbi request reprint Extracorporeal shock wave lithotripsy 25 years later: complications and their prevention
    Andreas Skolarikos
    Urology Department, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    Eur Urol 50:981-90; discussion 990. 2006
    ..We review the pathophysiology and possible prevention measures of complications after extracorporeal shock wave lithotripsy (ESWL)...
  92. doi request reprint Photoselective vaporization of the prostate to manage benign prostatic hyperplasia
    Gerasimos Alivizatos
    Second Urology Department, Athens Medical School, Sismanoglio Hospital, Athens, Greece
    J Endourol 22:2117-9. 2008
  93. ncbi request reprint Splenogonadal fusion: report of a case and review of the literature
    Gerasimos Alivizatos
    Second Urology Department of Athens Medical School, Athens, Greece
    Int J Urol 12:90-2. 2005
    ..Splenogonadal fusion, although a rare condition, may account for a non-malignant testicular mass and should be suspected in young patients with other congenital anomalies...
  94. ncbi request reprint Thalidomide and immunomodulatory drugs in the treatment of cancer
    Aristotle Bamias
    University of Athens School of Medicine, Department of Clinical Therapeutics, 227 Kifissias Avenue, Kifissia, Athens, 14561, Greece
    Expert Opin Investig Drugs 14:45-55. 2005
    ..They have already shown promising activity in multiple myeloma and are currently being evaluated in clinical studies...
  95. ncbi request reprint High-dose melphalan and autologous stem cell transplantation as consolidation treatment in patients with chemosensitive ovarian cancer: results of a single-institution randomized trial
    C Papadimitriou
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, Greece
    Bone Marrow Transplant 41:547-54. 2008
    ..In an intent-to-treat analysis, there were no significant differences between the two arms in TTP (P=0.059) as well as in overall survival (OS) (P=0.38)...
  96. ncbi request reprint Thalidomide in cancer medicine
    V Eleutherakis-Papaiakovou
    Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece
    Ann Oncol 15:1151-60. 2004
    ..Limited activity was demonstrated in patients with glioma, while thalidomide appears to be inactive in patients with head and neck cancer, breast or ovarian cancer...
  97. ncbi request reprint Epithelial ovarian carcinoma in younger vs older women: is age an independent prognostic factor? The Hellenic Oncology Cooperative Group experience
    D Pectasides
    Second Department of Internal Medicine, Oncology Section, University General Hospital Attikon, Athens, Greece
    Int J Gynecol Cancer 17:1003-10. 2007
    ..001). In conclusion, younger women with EOC have significantly improved survival compared to older patients. Age, PS, stage of the disease at diagnosis, and residual disease are important independent predictors for survival...
  98. ncbi request reprint Late relapse of epithelial ovarian cancer: a single institution experience
    A Bamias
    Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece
    Eur J Gynaecol Oncol 26:439-42. 2005
    ..Late relapses are infrequent in ovarian cancer. We present the characteristics and outcome of patients who relapsed at least five years after first-line chemotherapy...
  99. ncbi request reprint Is there a role for hyberbaric oxygen as primary treatment for grade IV radiation-induced haemorrhagic cystitis? a prospective pilot-feasibility study and review of literature
    Athanasios Dellis
    2nd Surgical Department, University of Athens, Aretaieion Hospital, Athens, Greece
    Int Braz J Urol 40:296-305. 2014
    ..One patient needed cystectomy, while all patients were alive at the end of follow-up. Conclusions: Early primary use of hyperbaric oxygen to treat radiation-induced grade IV cystitis is an effective and safe treatment option. ..
  100. doi request reprint Conservative and radiological management of simple renal cysts: a comprehensive review
    Andreas Skolarikos
    Athens Medical School, 2nd Department of Urology, Sismanoglio Hospital, Athens, Greece
    BJU Int 110:170-8. 2012
    ..Simple renal cysts may not require treatment when asymptomatic. Radiological intervention with the use of sclerosants needs further evaluation and comparison with other treatment methods...