P A Sarafidis

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi Proteinuria: natural course, prognostic implications and therapeutic considerations
    P A Sarafidis
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Minerva Med 98:693-711. 2007
  2. pmc Carvedilol in hypertension treatment
    Panagiotis C Stafylas
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Vasc Health Risk Manag 4:23-30. 2008
  3. pmc Total protein, albumin and low-molecular-weight protein excretion in HIV-positive patients
    Lucy J Campbell
    Academic Department of Renal Sciences, King s College London, London, United Kingdom
    BMC Nephrol 13:85. 2012
  4. doi Pharmacological management of hypertensive emergencies and urgencies: focus on newer agents
    Pantelis A Sarafidis
    Aristotle University of Thessaloniki, AHEPA Hospital, 1st Department of Medicine, Section of Nephrology and Hypertension, Thessaloniki, Greece
    Expert Opin Investig Drugs 21:1089-106. 2012
  5. doi Hypertension and symptomatic hypokalemia in a patient with simultaneous unilateral stenoses of intrarenal arteries and mesangioproliferative glomerulonephritis
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, First Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Greece
    Am J Kidney Dis 59:434-8. 2012
  6. ncbi A comparative evaluation of various methods for microalbuminuria screening
    Pantelis A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, Chicago, Ill, USA
    Am J Nephrol 28:324-9. 2008
  7. doi Diuretics in clinical practice. Part I: mechanisms of action, pharmacological effects and clinical indications of diuretic compounds
    Pantelis A Sarafidis
    1st Department of Medicine, Section of Nephrology and Hypertension, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, St Kiriakidi 1, 54636 Thessaloniki, Greece
    Expert Opin Drug Saf 9:243-57. 2010
  8. doi Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension
    Lina S Hatzistavri
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA Hospital, Aristotle University, Thessaloniki, Greece
    Am J Hypertens 22:1070-5. 2009
  9. doi Effect of thiazolidinediones on albuminuria and proteinuria in diabetes: a meta-analysis
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, First Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Am J Kidney Dis 55:835-47. 2010
  10. ncbi Antihypertensive agents, insulin sensitivity, and new-onset diabetes
    Pantelis A Sarafidis
    1st Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, St Kiriakidi 1, 546 36 Thessaloniki, Greece
    Curr Diab Rep 7:191-9. 2007

Collaborators

Detail Information

Publications46

  1. ncbi Proteinuria: natural course, prognostic implications and therapeutic considerations
    P A Sarafidis
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Minerva Med 98:693-711. 2007
    ....
  2. pmc Carvedilol in hypertension treatment
    Panagiotis C Stafylas
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Vasc Health Risk Manag 4:23-30. 2008
    ..This article summarizes the distinct pharmacologic, hemodynamic, and metabolic properties of carvedilol in relation to conventional beta-blockers, attempting to examine the potential use of this agent for hypertension treatment...
  3. pmc Total protein, albumin and low-molecular-weight protein excretion in HIV-positive patients
    Lucy J Campbell
    Academic Department of Renal Sciences, King s College London, London, United Kingdom
    BMC Nephrol 13:85. 2012
    ..We analysed 3 LMWP as well as protein and albumin in the urine of a sample of HIV positive patients...
  4. doi Pharmacological management of hypertensive emergencies and urgencies: focus on newer agents
    Pantelis A Sarafidis
    Aristotle University of Thessaloniki, AHEPA Hospital, 1st Department of Medicine, Section of Nephrology and Hypertension, Thessaloniki, Greece
    Expert Opin Investig Drugs 21:1089-106. 2012
    ..Although several short-acting intravenous antihypertensive agents are approved for this purpose, until recently little evidence from proper trials on the relative merits of different therapies was available...
  5. doi Hypertension and symptomatic hypokalemia in a patient with simultaneous unilateral stenoses of intrarenal arteries and mesangioproliferative glomerulonephritis
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, First Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Greece
    Am J Kidney Dis 59:434-8. 2012
    ....
  6. ncbi A comparative evaluation of various methods for microalbuminuria screening
    Pantelis A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, Chicago, Ill, USA
    Am J Nephrol 28:324-9. 2008
    ..We evaluated a new quantitative office-based method to assess urinary albumin excretion (UAE) and compared it to other established methods...
  7. doi Diuretics in clinical practice. Part I: mechanisms of action, pharmacological effects and clinical indications of diuretic compounds
    Pantelis A Sarafidis
    1st Department of Medicine, Section of Nephrology and Hypertension, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, St Kiriakidi 1, 54636 Thessaloniki, Greece
    Expert Opin Drug Saf 9:243-57. 2010
    ..Take home message: Knowledge of the pharmacologic properties and mechanisms of action of diuretic agents is a prerequisite for the successful choice and effective clinical use of these compounds...
  8. doi Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension
    Lina S Hatzistavri
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA Hospital, Aristotle University, Thessaloniki, Greece
    Am J Hypertens 22:1070-5. 2009
    ..This study aimed to investigate the effect of oral Mg(2+) supplementation on 24-h blood pressure (BP) and intracellular ion status in patients with mild hypertension...
  9. doi Effect of thiazolidinediones on albuminuria and proteinuria in diabetes: a meta-analysis
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, First Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Am J Kidney Dis 55:835-47. 2010
    ..Recent studies suggest that thiazolidinediones have renal benefits. We aimed to evaluate the effect of thiazolidinediones on urinary albumin and protein excretion in patients with diabetes mellitus...
  10. ncbi Antihypertensive agents, insulin sensitivity, and new-onset diabetes
    Pantelis A Sarafidis
    1st Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, St Kiriakidi 1, 546 36 Thessaloniki, Greece
    Curr Diab Rep 7:191-9. 2007
    ..This article presents and evaluates the current knowledge in this important area...
  11. ncbi Statins and blood pressure: is there an effect or not?
    Pantelis A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Clin Hypertens (Greenwich) 9:460-7. 2007
    ..This review summarizes existing data on the effect of statins on BP, aiming to give an overview of the current knowledge and to provide perspectives for future research in the field...
  12. ncbi Thiazolidinediones and diabetic nephropathy: need for a closer examination?
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Cardiometab Syndr 2:297-301. 2007
    ..After the latter issue is resolved, however, it would appear very interesting to conduct specific studies in patients with overt diabetic nephropathy to determine the effect of these agents on proteinuria and kidney disease progression...
  13. doi Thiazolidinedione derivatives in diabetes and cardiovascular disease: an update
    Pantelis A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Fundam Clin Pharmacol 22:247-64. 2008
    ..This article will discuss all the above issues attempting to provide an updated overview of this expanding field...
  14. ncbi Insulin resistance, microalbuminuria, and chronic kidney disease
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, First Department of Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, St Kiriakidi 1, 54636, Thessaloniki, Greece
    Curr Hypertens Rep 10:249-51. 2008
  15. doi Obesity, insulin resistance and kidney disease risk: insights into the relationship
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, First Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Curr Opin Nephrol Hypertens 17:450-6. 2008
    ..This increase may have an adverse impact not only on cardiovascular but also on chronic kidney disease...
  16. doi Insulin resistance and endothelin: another pathway for renal injury in patients with the cardiometabolic syndrome?
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Cardiometab Syndr 3:183-7. 2008
    ..This article discusses the existing data on the interactions between insulin resistance, hyperinsulinemia, and endothelin and how these can lead to renal damage in patients with the cardiometabolic syndrome...
  17. doi Diuretics in clinical practice. Part II: electrolyte and acid-base disorders complicating diuretic therapy
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, 1st Department of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, St Kiriakidi 1, 54636, Thessaloniki, Greece
    Expert Opin Drug Saf 9:259-73. 2010
    ....
  18. ncbi Validity and reproducibility of HOMA-IR, 1/HOMA-IR, QUICKI and McAuley's indices in patients with hypertension and type II diabetes
    P A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Hum Hypertens 21:709-16. 2007
    ..QUICKI displayed better reproducibility than the other indices...
  19. ncbi Effects of statins on blood pressure: a review of the experimental and clinical evidence
    Pantelis A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Curr Vasc Pharmacol 5:155-61. 2007
    ..Overall, current evidence suggests that statins can be associated with a mild beneficial effect on BP, but further research is needed to clarify the exact magnitude of this action, as well as its clinical relevance...
  20. ncbi The antinatriuretic effect of insulin: an unappreciated mechanism for hypertension associated with insulin resistance?
    Pantelis A Sarafidis
    First Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Am J Nephrol 27:44-54. 2007
    ....
  21. ncbi The effect of rosiglitazone on novel atherosclerotic risk factors in patients with type 2 diabetes mellitus and hypertension. An open-label observational study
    Panteleimon A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, 54636 Thessaloniki, Greece
    Metabolism 54:1236-42. 2005
    ..The overall effect of rosiglitazone on cardiovascular risk factors seems positive but must be further evaluated...
  22. ncbi Insulin resistance, hyperinsulinemia, and hypertension: an epidemiologic approach
    Pantelis A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    J Cardiometab Syndr 1:334-42; quiz 343. 2006
    ..This review summarizes and evaluates the relevant epidemiologic evidence to elucidate an important aspect of the relationship between hypertension and the cardiometabolic syndrome...
  23. ncbi The metabolic syndrome: a glance at its history
    Panteleimon A Sarafidis
    First Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Hypertens 24:621-6. 2006
    ....
  24. ncbi Ambulatory blood pressure reduction after rosiglitazone treatment in patients with type 2 diabetes and hypertension correlates with insulin sensitivity increase
    Panteleimon A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Hypertens 22:1769-77. 2004
    ..Thiazolidinediones are antihyperglycemic agents that decrease insulin resistance...
  25. doi Epidemiology of resistant hypertension
    Pantelis A Sarafidis
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Clin Hypertens (Greenwich) 13:523-8. 2011
    ..This article will discuss current knowledge and associated future implications relevant to the epidemiology of resistant hypertension...
  26. ncbi Actions of peroxisome proliferator-activated receptors-gamma agonists explaining a possible blood pressure-lowering effect
    Panteleimon A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, St Kiriakidi 1, 54006 Thessaloniki, Greece
    Am J Hypertens 19:646-53. 2006
    ..This review summarizes the current evidence about these actions of TZD that could positively influence BP, representing possible mechanisms of BP amelioration...
  27. ncbi Insulin resistance, hyperinsulinemia, and renal injury: mechanisms and implications
    Pantelis A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Nephrol 26:232-44. 2006
    ..This review analyzes the above and other potential mechanisms, through which insulin resistance and hyperinsulinemia can contribute to renal injury...
  28. ncbi Antihypertensive treatment with beta-blockers and the spectrum of glycaemic control
    P A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, 1700 West Van Buren, Suite 470, Chicago, IL 60612, USA
    QJM 99:431-6. 2006
    ....
  29. ncbi Non-esterified fatty acids and blood pressure elevation: a mechanism for hypertension in subjects with obesity/insulin resistance?
    P A Sarafidis
    Department of Preventive Medicine, Hypertension Clinical Research Center, Rush University Medical Center, Chicago, IL 60612, USA
    J Hum Hypertens 21:12-9. 2007
    ..The above data support a possible important role of NEFA in hypertension development in patients with obesity and the metabolic syndrome and raise hypotheses for future research...
  30. ncbi Review: Insulin and endothelin: an interplay contributing to hypertension development?
    Pantelis A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, 1700 West Van Buren, Suite 470, Chicago, Illinois 60612, USA
    J Clin Endocrinol Metab 92:379-85. 2007
    ..The aim of this article was to review the existing data on the interactions among insulin, insulin resistance, and endothelin and how those contribute to the development of hypertension in insulin-resistant states...
  31. ncbi The effect of rosiglitazone on urine albumin excretion in patients with type 2 diabetes mellitus and hypertension
    Panteleimon A Sarafidis
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    Am J Hypertens 18:227-34. 2005
    ..The aim of this study was to determine the effect of rosiglitazone on urine albumin excretion (UAE) in patients with type 2 diabetes mellitus (DM) and hypertension...
  32. ncbi Protection of the kidney by thiazolidinediones: an assessment from bench to bedside
    P A Sarafidis
    Department of Preventive Medicine, Hypertension Clinical Research Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Kidney Int 70:1223-33. 2006
    ..This paper summarizes all the data from clinical and experimental studies relevant to a possible renoprotective effect of TZDs and discusses actions of these compounds that may contribute toward this effect...
  33. doi Insulin sensitivity increase after calcium supplementation and change in intraplatelet calcium and sodium-hydrogen exchange in hypertensive patients with Type 2 diabetes
    M I Pikilidou
    1st Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Diabet Med 26:211-9. 2009
    ....
  34. doi Low-dose atorvastatin reduces ambulatory blood pressure in patients with mild hypertension and hypercholesterolaemia: a double-blind, randomized, placebo-controlled study
    A I Kanaki
    Section of Nephrology and Hypertension, 1st Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Hum Hypertens 26:577-84. 2012
    ..This beneficial effect of atorvastatin on BP may represent another pathway through which this drug class provides cardiovascular risk reduction...
  35. ncbi Cost-effectiveness of losartan in diabetic nephropathy: a Greek perspective
    P C Stafylas
    First Department of Medicine, AHEPA University Hospital, Aristotle University, Thessaloniki, Greece
    J Nephrol 20:703-15. 2007
    ..A secondary aim was to approximate the direct health care cost of renal replacement therapy (RRT) in Greece...
  36. ncbi Prevalence, awareness, treatment and control of hypertension in employees of factories of Northern Greece: the Naoussa study
    P A Sarafidis
    1st Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    J Hum Hypertens 18:623-9. 2004
    ..There is also a difference in awareness and treatment in favour of women compared to men and in favour of patients >/=45 years of age compared to those <45 years of age...
  37. ncbi An economic evaluation of the 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of mild-to-moderate hypertension in Greece
    Panagiotis C Stafilas
    1st Department of Medicine, AHEPA University Hospital, Aristotle University, St Kiriakidi 1, 54006 Thessaloniki, Greece
    Am J Hypertens 18:1233-40; discussion 1241-2. 2005
    ..The aim of this study was to compare the cost-effectiveness of each one of the major antihypertensive agents as monotherapy in the management of mild-to-moderate hypertension in Greece, when following the 2003 ESH-ESC guidelines...
  38. doi 24-hour intraocular pressure and blood pressure levels with latanoprost/timolol fixed combination versus timolol
    A G P Konstas
    1st Department of Medicine, corrected AHEPA Hospital, Thessaloniki, Greece
    Curr Eye Res 34:369-77. 2009
    ..To evaluate 24-hr intraocular pressure (IOP) and blood pressure (BP) with timolol or latanoprost/timolol fixed combination (LTFC)...
  39. ncbi Quantitative evaluation of the systemic effects of transposed basilic vein to brachial artery arteriovenous fistula: a prospective study
    N Saratzis
    1st Department of Surgery and Vascular Surgery, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece
    J Vasc Access 9:285-90. 2008
    ..The purpose of this study is to evaluate the effects of BBAVF on systemic arterial pressure, cardiac function, and upper limb ischemia (ischemic steal syndrome) utilizing reproducible quantitative methods...
  40. ncbi Epigenetic mechanisms and kidney diseases
    V Liakopoulos
    Division of Nephrology, 1st Department of Internal Medicine, AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Curr Med Chem 18:1733-9. 2011
    ....
  41. ncbi Diabetic nephropathy and antihypertensive treatment: what are the lessons from clinical trials?
    Anastasios N Lasaridis
    First Department of Internal Medicine, Faculty of Medicine, Aristotle University of Thessaloniki, AHEPA University Hospital, St Kiriakidi 1, 540 06 Thessaloniki, Greece
    Am J Hypertens 16:689-97. 2003
    ..Another issue is that the vast majority of the patients need so many nonstudy drugs to keep their pressure under control, that the isolation of advantageous effects of certain drugs seems unrealistic...
  42. ncbi Do the metabolic effects of beta blockers make them leading or supporting antihypertensive agents in the treatment of hypertension?
    Panteleimon A Sarafidis
    1st Department of Preventive Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Greece
    J Clin Hypertens (Greenwich) 8:351-6; quiz 357-8. 2006
    ....
  43. ncbi Cardiometabolic syndrome and chronic kidney disease: what is the link?
    Panteleimon A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    J Cardiometab Syndr 1:58-65. 2006
    ....
  44. ncbi Are beta blockers passé for the treatment of hypertension?
    Panteleimon A Sarafidis
    J Clin Hypertens (Greenwich) 8:239-40. 2006
  45. ncbi Antihypertensive therapy and the risk of new-onset diabetes
    Panteleimon A Sarafidis
    Diabetes Care 29:1167-9. 2006
  46. ncbi Level of kidney function determines cardiovascular fate after coronary bypass graft surgery
    Panteleimon A Sarafidis
    Circulation 113:1046-7. 2006