Research Topics
| George H SakorafasSummaryAffiliation: University of Athens Country: Greece Publications
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Detail Information
Publications
Surgical management of chronic pancreatitis: current concepts and future perspectivesGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Int Surg 88:211-8. 2003..In recent years, a clear trend in favor of resectional procedures (including the newer nonanatomic pancreatic resections) has been observed...
Optimal management of ductal carcinoma in situ of the breastGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Surg Oncol 12:221-40. 2003..The use of systemic therapy in patients with invasive recurrence should be based on standard criteria for invasive breast cancer...
Historical evolution of thyroid surgery: from the ancient times to the dawn of the 21st centuryGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Arkadias 19 21, 115 26, Athens, Greece
World J Surg 34:1793-804. 2010....
Good results after major pancreatic resections in a middle-volume centerGeorge Peros
4th Department of Surgery, University Hospital Attikon, Medical School, Athens University, Athens, Greece
Pancreas 39:411-4. 2010..Recently, hospital and surgeon volume is widely discussed as a prognostic factor after major pancreatic surgery. We present our experience regarding major pancreatectomy in a middle-volume center...
External branch of the superior laryngeal nerve: applied surgical anatomy and implications in thyroid surgeryGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Am Surg 78:986-91. 2012..An in-depth knowledge of the surgical anatomy of the EBSLN is therefore required from the part of the operating surgeon to protect this nerve during thyroid surgery...
Small (<10 mm) thyroid nodules; how aggressively should they be managed?George H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon Hospital, Athens, Greece
Onkologie 33:61-4. 2010..US-guided FNA should be performed when malignancy is a concern, regardless of nodule size, to avoid missing or undertreating a curable cancer...
Retained surgical sponges: what the practicing clinician should knowGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, ATTIKON U Hospital, Arkadias 19 21, 115 26, Athens, Greece
Langenbecks Arch Surg 395:1001-7. 2010....
Primary pancreatic cystic neoplasms of the pancreas revisited. Part IV: rare cystic neoplasmsGeorge H Sakorafas
4th Department of Surgery, Medical School, University of Athens, Attikon University Hospital, Athens, 12462, Greece
Surg Oncol 21:153-63. 2012..Moreover, each of these unusual neoplasms has their own natural history/tumor biology and may require a different level of operative aggressiveness to obtain the optimal outcome...
Individuals at high-risk for pancreatic cancer development: management options and the role of surgeryGeorge H Sakorafas
Department of Surgery, Athens University, Medical School, Arkadias 19 21, Athens, Greece
Surg Oncol 21:e49-58. 2012..Despite that experience still remains limited, there is evidence that this aggressive strategy allows early detection of neoplastic lesions, thereby improving the effectiveness of surgery and prognosis...
Myoid hamartoma of the breast: a case report and review of the literatureVania Stafyla
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Breast J 13:85-7. 2007..The patient is well 4 years later without tumor recurrence. Breast myoid hamartomas are exceptionally rare benign lesions; complete surgical excision achieves cure...
Cervical lymph node dissection in papillary thyroid cancer: current trends, persisting controversies, and unclarified uncertaintiesGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School ATTIKON University Hospital, Arkadias 19 21, GR 115 26, Athens, Greece
Surg Oncol 19:e57-70. 2010..Experience is therefore required from the part of the operating surgeon, who should be able to perform safely CLND at the time of initial surgery (thyroidectomy), to minimize surgical morbidity...
Primary thyroid lymphoma (correction of lympoma): diagnostic and therapeutic dilemmasGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Surg Oncol 19:e124-9. 2010..A high index of suspicion from the part of the clinician is required to achieve early diagnosis and prompt treatment of this potentially curable thyroid malignancy...
Abdominal wall endometrioma: a case report and review of the literatureChristos Nissotakis
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
AORN J 91:730-42; quiz 743-5. 2010....
Incidental parathyroidectomy during thyroid surgery: an underappreciated complication of thyroidectomyGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, 19 21 Arkadias Street, Athens, GR 115 26, Greece
World J Surg 29:1539-43. 2005..Incidental parathyroidectomy may be considered as a potentially preventable but clinically minor complication of thyroid surgery...
Thyroid nodules: does the suspicion for malignancy really justify the increased thyroidectomy rates?George H Sakorafas
Fourth Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Surg Oncol 15:43-55. 2006..However, accurate preoperative diagnosis of thyroid cancer within a thyroid nodule is not always possible and, although the problem of unnecessary surgery can further be diminished, it cannot be completely eliminated...
The role of surgery in the management of septic shock--intra-abdominal causes of sepsisGeorge H Sakorafas
Fourth Department of Surgery, Medical School, Athens University, Athens, Greece
AORN J 85:280-94; quiz 295-8. 2007
Transanal circular stapler technique: a simple and highly effective method for the management of high-grade stenosis of low colorectal anastomosesChristos Nissotakis
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Surg Laparosc Endosc Percutan Tech 18:375-8. 2008..We present 2 patients successfully treated by this technique [in one, the combined (transanal plus transabdominal) approach was used] and the relevant literature is briefly reviewed...
The management of women at high risk for the development of breast cancer: risk estimation and preventative strategiesGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Cancer Treat Rev 29:79-89. 2003..It is hoped that other preventative methods, such as gene therapy based on an accurate identification of specific genetic changes, will be developed in the future...
Bilateral, primary, low-grade, diffuse B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) of the breastBasil Zobolas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Breast J 8:382. 2002
Molecular biology of pancreatic cancer: how useful is it in clinical practice?George H Sakorafas
Fourth Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
JOP 13:332-7. 2012..It is currently accepted that pancreatic cancer has a genetic component. The real challenge is now how these impressive advances could be used in clinical practice...
Small intestinal nonmeckelian diverticulosisKonstantinos Makris
Department of Surgery, Metropolitan Hospital, Athens, Greece
J Clin Gastroenterol 43:201-7. 2009..The extent of resection may be a problem, especially in patients with extensive disease involving large parts of the bowel. In these cases, clinical judgment is required from the part of surgeon to avoid short bowel syndrome...
Conservative treatment of acute appendicitis: heresy or an effective and acceptable alternative to surgery?George H Sakorafas
Fourth Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Eur J Gastroenterol Hepatol 23:121-7. 2011....
Celiac artery stenosis: an underappreciated and unpleasant surprise in patients undergoing pancreaticoduodenectomyGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
J Am Coll Surg 206:349-56. 2008
Breast cancer surgery: an historical narrative. Part I. From prehistoric times to RenaissanceGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Eur J Cancer Care (Engl) 18:530-44. 2009..Surgery was often 'heroic' but primitive and even inhumane by current standards. Therapeutic nihilism was the prevailing altitude regarding breast cancer, at least among the vast majority of surgeons...
Ultrasound-guided catheterization of the internal jugular vein in oncologic patients; comparison with the classical anatomic landmark technique: a prospective studyKonstantinos Serafimidis
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Int J Surg 7:526-8. 2009..To compare the traditional anatomic landmark technique with the ultrasound-guided method for central venous catheterization...
Sequelae following axillary lymph node dissection for breast cancerGeorge H Sakorafas
Attikon University Hospital, 4th Department of Surgery, Athens University, Medical School, Arkadias 19 21, GR 11526, Athens, Greece
Expert Rev Anticancer Ther 6:1629-38. 2006..The introduction of the technique of sentinel lymph node biopsy in clinical practice has resulted in a significant reduction in the incidence of post-ALND complications...
Women at high risk for breast cancer: preventive strategiesGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Mt Sinai J Med 69:264-6. 2002..However, at the present time, close surveillance, which include breast self-examination, annual or semiannual physical examinations, and annual mammography starting at age 30, remains the most widely accepted method...
Spontaneous cyst-cutaneous fistula: an extremely rare presentation of hydatid liver cystGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Am J Surg 192:205-6. 2006
Ectopic intrathoracic thyroid: case reportGeorge H Sakorafas
Department of Oncology, 251 Hellenic Force Hospital, Athens, Greece
Mt Sinai J Med 71:131-3. 2004..Ectopic intrathoracic thyroid is a rare presentation of thyroid disease and comprises about 1% of all mediastinal tumors. Its removal usually necessitates thoracotomy or sternotomy. The relevant literature is briefly reviewed...
Necrotizing acute pancreatitis current status - emerging new strategies in surgical managementGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Infect Disord Drug Targets 12:138-43. 2012..Results have been impressive, but experience currently is limited to only a few centers around the world...
Risk estimation for breast cancer development; a clinical perspectiveGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Surg Oncol 10:183-92. 2002....
Carcinoid tumors of the duodenum and the ampulla of Vater: current diagnostic and therapeutic approach in a series of 8 patients. Case seriesGeorge C Nikou
Section of Gastrointestinal Neuroendocrinology, First Department of Propaedeutic Internal Medicine of Athens University Medical School, Laiko Hospital, Athens, Greece
Int J Surg 9:248-53. 2011..To describe the specific characteristics of duodenal/perivaterian carcinoids and to analyze the diagnostic/therapeutic approach...
Peritoneal tuberculosis in pregnancy mimicking advanced ovarian cancer: a plea to avoid hasty, radical and irreversible surgical decisionsGeorge H Sakorafas
4th Department of Surgery, Attikon University Hospital, Athens University, Medical School Athens, Athens, Greece
Int J Infect Dis 13:e270-2. 2009..The patient was successfully treated conservatively. Hasty decisions to undertake radical and irreversible surgery should be avoided; this type of surgery should be performed only after histological confirmation...
Thyroid nodules; interpretation and importance of fine-needle aspiration (FNA) for the clinician - practical considerationsGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Surg Oncol 19:e130-9. 2010..This is due to the fact that during the last decade there is a clear trend toward radical surgical management of thyroid nodular disease (both benign and malignant) by total/near-total thyroidectomy...
Cystic neoplasms of the pancreas; what a clinician should knowGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force HAF Hospital, Messogion and Katehaki Avenue, 115 25 Athens, Greece, and Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Cancer Treat Rev 31:507-35. 2005..In the absence of invasive disease, prognosis is excellent after appropriate surgery. The presence of invasive malignancy signifies a poor prognosis...
Intraductal papillary mucinous neoplasms of the pancreas: a surgical perspectiveGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Arkadias 19 21, GR 115 26 Athens, Greece
Surg Oncol 14:155-78. 2005..However, invasive IPMNs behave quite similar to ductal adenocarcinoma of the pancreas when analyzed stage-by-stage, with a slightly better prognosis; however, even after an R0 resection, recurrence is common...
The role of surgery in the management of septic shock--extra-abdominal causes of sepsisGeorge H Sakorafas
Fourth Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
AORN J 85:137-46; quiz 147-50. 2007..This is the first of two articles presenting current information on the role of surgery in the management of a patient with septic shock. This article describes extra-abdominal sources of sepsis...
Asymptomatic cholelithiasis: is cholecystectomy really needed? A critical reappraisal 15 years after the introduction of laparoscopic cholecystectomyGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Arkadias 19 21, GR 115 26, Athens, Greece
Dig Dis Sci 52:1313-25. 2007..Management options should be extensively discussed with the patient; he or she should be actively involved in the process of therapeutic decision making...
Applied vascular anatomy of the colon and rectum: clinical implications for the surgical oncologistGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Surg Oncol 15:243-55. 2006..This review summarizes currently available data regarding vascular anatomy of the colon and rectum, from a surgical perspective...
Preoperative detection of cervical lymph node metastases in papillary thyroid cancer: a surgical perspectiveGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
Onkologie 32:762-6. 2009..A compartment-oriented cervical lymph node dissection should be performed at the time of thyroidectomy if preoperative evaluation reveals cervical lymphadenopathy...
Potential pitfalls in the management of primary pancreatic cystic neoplasmsGeorge H Sakorafas
4th Department of Surgery, Athens University Medical School, Attikon University Hospital, Athens, Greece
Onkologie 34:332-6. 2011..Clinical judgment is also required on the part of the surgeon to select the optimal procedure and to avoid severe pitfalls in the surgical management of these neoplasms...
Mechanisms and natural history of pain in chronic pancreatitis: a surgical perspectiveGeorge H Sakorafas
Fourth Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
J Clin Gastroenterol 41:689-99. 2007..The knowledge of the pathophysiologic basis and of natural course of pain in CP is of paramount importance for the surgeon to select appropriate therapy for the individual patient with CP...
Malignant fibrous histiocytoma of the liver: a case report and review of the literatureGeorge Anagnostopoulos
Department of Gastroenterology, 251 Hellenic Air Force HAF Hospital, Athens, Greece
Mt Sinai J Med 72:50-2. 2005..Most of the tumor cells and giant cells were vimentin and a 1-antichymotrypsin positive. Histopathological findings were consistent with an MFH of the storiform / pleomorphic subtype. The literature is briefly reviewed...
Septic shock; current pathogenetic concepts from a clinical perspectiveAdelais G Tsiotou
Department of Anesthesiology, Children's Hospital P and A Kyriakou, Athens, Greece
Med Sci Monit 11:RA76-85. 2005....
Abdominal desmoid tumorsGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Arkadias 19 21, GR 115 26, Athens, Greece
Surg Oncol 16:131-42. 2007..Adjuvant therapy should be considered in selected cases; the role of other management options (including gene transfer therapy) is currently under intensive investigation...
The origins of radical mastectomyGeorge H Sakorafas
Attikon University Hospital, Athens University Medical School, Athens, Greece
AORN J 88:605-8. 2008....
Alkaline reflux gastritis: early and late results of surgeryBasile Zobolas
Department of Surgery, Metaxa Hospital, Botasi 51 Str, 18537, Peireas, Greece
World J Surg 30:1043-9. 2006..The Roux stasis syndrome is a frequent complication following Roux-en-Y reconstruction, but quality of life is significantly improved. Careful patient selection is essential to achieve satisfactory results...
Combined side-to-end anastomosis with temporary end colostomy for the management of selected left-sided colonic emergenciesMichael Safioleas
2nd Department of Propaedeutic Surgery, Laikon General Hospital, Athens University Medical School, Athens, Greece
Am Surg 77:447-50. 2011..Its main advantage is that it greatly facilitates colostomy closure, which is performed earlier compared with the colostomy closure after a typical Hartmann's procedure...
Papillary thyroid microcarcinoma: a surgical perspectiveGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Arkadias 19 21, GR 11526 Athens, Greece
Cancer Treat Rev 31:423-38. 2005..Suppression therapy is needed after surgical management. Despite the potential for neck lymph node and even distant metastases, the biological behavior of PTMC is in general benign and the prognosis is very good...
Proximal pancreatectomy in the surgical management of chronic pancreatitisGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Forces HAF, General Hospital, Athens, Greece
J Clin Gastroenterol 34:72-6. 2002..However, when there is strong suspicion of an underlying malignancy, a pancreatoduodenectomy should be considered in surgically fit patients, as this is an adequate procedure for both CP and pancreatic cancer...
Large somatostatin-producing endocrine carcinoma of the ampulla of vater in association with GIST in a patient with von Recklinghausen's disease. Case report and review of the literatureGeorge H Sakorafas
Fourth Department of Surgery, Athens University Medical School, Attikon University Hospital, Athens, Greece
JOP 9:633-9. 2008..Somatostatin-producing endocrine tumors of the duodenum are very rare neoplasms of the gastrointestinal tract. These tumors may be associated with von Recklinghausen's disease...
Small bowel perforation secondary to metastatic lung cancer: a case report and review of the literatureGeorge H Sakorafas
Department of Surery, Air Force Hospital, Athens, Greece
Mt Sinai J Med 70:130-2. 2003..Aggressive investigation and early surgery is the only method for providing palliation to these patients. However, morbidity and mortality remain high and the prognosis is dire...
Lobular carcinoma in situ of the breast within a fibroadenoma. A case reportVania Stafyla
Department of Surgery, 251 Hellenic Air Force (HAF) Hospital, Arkadias 19-21, Athens 115 26, Greece
Gynecol Oncol 94:572-4. 2004..Close surveillance following local excision/biopsy is the preferred management for LCIS within a fibroadenoma...
Biliary peritonitis due to fistulous tract rupture following a T-tube removalGeorge H Sakorafas
Department of Surgery, Hellenic Air Force Hospital, Athens, Greece
N Z Med J 118:U1522. 2005..A Nelaton catheter was inserted through this opening and advanced toward the biliary tree and secured in place by a suture ligature. Postoperative course was uneventful...
Open preperitoneal mesh repair of recurrent inguinal and femoral herniasGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, Athens, Greece
Mt Sinai J Med 72:342-5. 2005..Mean follow-up was 45 months. The procedure was safe (no significant early and late morbidity) and achieved a safe repair (no recurrence during the follow-up period)...
Isolated metachronous contralateral adrenal metastasis from renal cell carcinomaGeorge H Sakorafas
Fourth Department of Surgery, Athens University, Medical School, Attikon University Hospital, 251 Hellenic Air Force Hospital, Athens, Greece
Mt Sinai J Med 73:822-4. 2006..Surgery is the only effective management option and should be offered to these patients...
Principles of war surgery: current concepts and future perspectivesGeorge H Sakorafas
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, GR 115 26, Athens, Greece
Am J Emerg Med 26:480-9. 2008..Military surgeons are now facing new challenges; appropriate education is required to achieve success in their mission...
Recent advances and current controversies in the management of DCIS of the breastGeorge H Sakorafas
4th Department of Surgery, Attikon Hospital, Athens University, Medical School, Arkadias 19 21, GR 115 26 Athens, Greece
Cancer Treat Rev 34:483-97. 2008..Additionally, and controversial, there is evidence that aromatase inhibitors may be better than tamoxifen in the management of DCIS...
Lymphedema following axillary lymph node dissection for breast cancerGeorge H Sakorafas
4th Department of Surgery, Attikon University Hospital, Athens University, Medical School, Arkadias 19 21, GR 115 26 Athens, Greece
Surg Oncol 15:153-65. 2006..Prevention is of key importance to avoid lymphedema formation. The application of the sentinel lymph node biopsy in the management of breast cancer has been associated with a reduced incidence of lymphedema formation...
Disseminated colon cancer with severe peripheral blood eosinophilia and elevated serum levels of interleukine-2, interleukine-3, interleukine-5, and GM-CSFGeorge K Anagnostopoulos
J Surg Oncol 89:273-5. 2005
Contrast-enhanced magnetic resonance imaging has a high sensitivity for detection of breast lesionsGeorge H Sakorafas
Breast J 8:121. 2002
