Panos Roussos

Summary

Affiliation: University of Crete
Country: Greece

Publications

  1. ncbi request reprint Planning, decision-making and the COMT rs4818 polymorphism in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Crete, Greece
    Neuropsychologia 46:757-63. 2008
  2. doi request reprint Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Greece
    Biol Psychiatry 66:997-1004. 2009
  3. pmc The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Neuropsychopharmacology 36:1677-88. 2011
  4. doi request reprint The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Biol Psychiatry 69:479-86. 2011
  5. doi request reprint A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Greece
    Biol Psychiatry 65:1063-70. 2009
  6. doi request reprint Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Greece
    Neuropsychopharmacology 33:3058-68. 2008
  7. doi request reprint The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Greece
    Bipolar Disord 13:250-9. 2011
  8. doi request reprint Cognitive and emotional processing associated with the Season of Birth and dopamine D4 receptor gene
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Neuropsychologia 48:3926-33. 2010
  9. ncbi request reprint Low baseline startle and deficient affective startle modulation in remitted bipolar disorder patients and their unaffected siblings
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion 71003, Greece
    Psychophysiology 47:659-68. 2010
  10. doi request reprint Comparison of ketanserin, buspirone and propranolol on arousal, pupil size and autonomic function in healthy volunteers
    Vassilis Koudas
    Department of Psychiatry and Behavioral Sciences, Medical School, University of Crete, P O Box 2208, Heraklion, 71003, Crete, Greece
    Psychopharmacology (Berl) 205:1-9. 2009

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Planning, decision-making and the COMT rs4818 polymorphism in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Crete, Greece
    Neuropsychologia 46:757-63. 2008
    ..While high prefrontal dopamine levels may be advantageous for non-emotional problem solving, they lead to disadvantageous choices when decision-making depends on processing of emotional feedback...
  2. doi request reprint Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Greece
    Biol Psychiatry 66:997-1004. 2009
    ..Here, we explored the effects of the synonymous COMT rs4818 C/G polymorphism and tolcapone on PPI and working memory...
  3. pmc The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Neuropsychopharmacology 36:1677-88. 2011
    ....
  4. doi request reprint The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Biol Psychiatry 69:479-86. 2011
    ....
  5. doi request reprint A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Greece
    Biol Psychiatry 65:1063-70. 2009
    ..We assessed the relationship between these high-risk PRODH polymorphisms and schizophrenia-related endophenotypes in a large and highly homogeneous cohort of healthy males...
  6. doi request reprint Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Greece
    Neuropsychopharmacology 33:3058-68. 2008
    ..These results suggest that early information processing and working memory may both depend on PFC DA signaling, and that they may both relate to PFC DA levels according to an inverted U-shaped curve function...
  7. doi request reprint The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Greece
    Bipolar Disord 13:250-9. 2011
    ..The aim of this study was to examine the phenotypic consequences of the risk CACNA1C and ANK3 alleles in a large homogeneous cohort of healthy young males...
  8. doi request reprint Cognitive and emotional processing associated with the Season of Birth and dopamine D4 receptor gene
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Neuropsychologia 48:3926-33. 2010
    ..SOB should be included in future studies of risky behaviors and behavioral genetic studies of the dopamine system...
  9. ncbi request reprint Low baseline startle and deficient affective startle modulation in remitted bipolar disorder patients and their unaffected siblings
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion 71003, Greece
    Psychophysiology 47:659-68. 2010
    ..Low startle and blunted startle reactivity may represent trait deficits in remitted BD patients and their relatives, possibly associated with attentional deficits and adaptive down-regulation of emotion...
  10. doi request reprint Comparison of ketanserin, buspirone and propranolol on arousal, pupil size and autonomic function in healthy volunteers
    Vassilis Koudas
    Department of Psychiatry and Behavioral Sciences, Medical School, University of Crete, P O Box 2208, Heraklion, 71003, Crete, Greece
    Psychopharmacology (Berl) 205:1-9. 2009
    ..The human pupil may be a suitable physiological test system for the assessment of excessive daytime sleepiness (EDS), but pupillometric assessment could be confounded by medication for comorbid hypertension and mood disorders...
  11. doi request reprint The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Greece
    Biol Psychiatry 64:235-40. 2008
    ..The Ser9Gly polymorphism is a common variant of the DRD(3) gene and determines the gain of function of the D(3) receptor. This is the first study to examine the influence of the DRD(3) Ser9Gly polymorphism on human PPI...
  12. doi request reprint Cognitive and emotional processing in high novelty seeking associated with the L-DRD4 genotype
    Panos Roussos
    Department of Psychiatry and Behavioral Sciences, University of Crete, Heraklion, Greece
    Neuropsychologia 47:1654-9. 2009
    ..The proposed role of the NS phenotype in human evolution and in disorders of impulsivity is discussed under the light of the present findings...
  13. doi request reprint Sustained attention and working memory deficits follow a familial pattern in schizophrenia
    Stella G Giakoumaki
    Department of Psychology, University of Crete, Rethymno, Greece
    Arch Clin Neuropsychol 26:687-95. 2011
    ..Reaction time and false alarm rates are suggested as additional useful endophenotypic measures that could potentially account for differences in performance in tasks that are not purported to examine the specific measures per se...
  14. ncbi request reprint Disruption of prepulse inhibition of the startle reflex by the preferential D(3) agonist ropinirole in healthy males
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, P O Box 2208, Heraklion, 71003, Crete, Greece
    Psychopharmacology (Berl) 194:289-95. 2007
    ..Emerging evidence from agonist-antagonist studies suggests a role for the dopamine D(3) receptor subtype in the regulation of PPI in animals, but such evidence is lacking for human subjects...
  15. doi request reprint Tolcapone, COMT polymorphisms and pharmacogenomic treatment of schizophrenia
    Panos Bitsios
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, PO Box 2208, University of Crete, Heraklion 71003, Crete, Greece
    Pharmacogenomics 12:559-66. 2011
    ..It will soon be understood if tolcapone represents one of the first hypothesis-driven, biology-based, genotype-specific, targeted treatments of cognitive and negative symptoms of schizophrenia...
  16. ncbi request reprint The CSMD1 genome-wide associated schizophrenia risk variant rs10503253 affects general cognitive ability and executive function in healthy males
    Erasmia Koiliari
    Department of Psychiatry, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Schizophr Res 154:42-7. 2014
    ..2, has reached genome-wide support as a risk factor for schizophrenia. There is initial but inconclusive evidence for a role of this variant in aspects of cognition...
  17. ncbi request reprint The 5-min pupillary alertness test is sensitive to modafinil: a placebo controlled study in patients with sleep apnea
    Alexandra Nikolaou
    Department of Psychiatry and Behavioral Sciences, Medical School, University of Crete, P O Box 2208, Heraklion 71003, Crete, Greece
    Psychopharmacology (Berl) 196:167-75. 2008
    ..The extent of pupillary miosis during 5 min in darkness is a simple, recently introduced alertness test which may become useful in the clinical assessment of normal and pathological sleepiness...
  18. ncbi request reprint Evidence of disrupted prepulse inhibition in unaffected siblings of bipolar disorder patients
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Medical School, University of Crete, Crete, Greece
    Biol Psychiatry 62:1418-22. 2007
    ..To address this issue, the present study examined whether disrupted PPI is present in individuals at high risk for BD...
  19. doi request reprint Cognitive and personality analysis of startle reactivity in a large cohort of healthy males
    Stella G Giakoumaki
    Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece Department of Psychology, University of Crete, Rethymno, Crete, Greece Electronic address
    Biol Psychol 94:582-91. 2013
    ..It is possible that the "non-responsive" status may capture disease related features such as executive dysfunction. ..