Konstantinos Poulas

Summary

Affiliation: University of Patras
Country: Greece

Publications

  1. doi request reprint Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine
    Konstantinos Poulas
    Department of Pharmacy, University of Patras, GR 26500, Patras, Greece
    J Neuroimmunol 250:94-8. 2012
  2. doi request reprint Population-ethnic group specific genome variation allele frequency data: a querying and visualization journey
    Emmanouil Viennas
    Department of Computer Engineering and Informatics, University of Patras, Patras, Greece
    Genomics 100:93-101. 2012
  3. pmc Developments in FINDbase worldwide database for clinically relevant genomic variation allele frequencies
    Petros Papadopoulos
    Department of Pharmacy, School of Health Sciences, University of Patras, GR 26504, Patras, Greece, Department of Computer Engineering and Informatics, Faculty of Engineering, University of Patras, GR 26504, Patras, Greece, Faculty of Medicine and Pharmacy, Human Genomic Center, University Mohammed V Souissi, 11400, Rabat, Morocco and Department of Computer and Informatics Engineering, Technological Educational Institute of Western Greece, GR 26334, Patras, Greece
    Nucleic Acids Res 42:D1020-6. 2014
  4. pmc Recent advances in genetic predisposition of myasthenia gravis
    Zoi Zagoriti
    Laboratory of Molecular Biology and Immunology, Department of Pharmacy, School of Health Sciences, University of Patras, 26504 Rio, Patras, Greece
    Biomed Res Int 2013:404053. 2013
  5. doi request reprint Scale up and safety parameters of antigen specific immunoadsorption of human anti-acetylcholine receptor antibodies
    George Lagoumintzis
    Department of Pharmacy, University of Patras, GR 26500, Patras, Greece
    J Neuroimmunol 267:1-6. 2014
  6. doi request reprint Genomic variation in the MAP3K5 gene is associated with β-thalassemia disease severity and hydroxyurea treatment efficacy
    Christina Tafrali
    University of Patras, School of Health Sciences, Department of Pharmacy, University Campus, Rion, Patras, Greece
    Pharmacogenomics 14:469-83. 2013
  7. doi request reprint Introducing dAUTObase: a first step towards the global scale geoepidemiology of autoimmune syndromes and diseases
    Vassiliki A Gkantouna
    Department of Computer Engineering and Informatics, University of Patras, Rio Patras, 26500, Greece, Department of Pharmacy, University of Patras, Rio Patras 26500, Greece, Department of Computer and Informatics Engineering, Technological Educational Institute of Western Greece, M Alexandrou 1, Koukouli Patras 26334, Greece
    Bioinformatics 31:581-6. 2015
  8. pmc Genetics of myasthenia gravis: a case-control association study in the Hellenic population
    Zoi Zagoriti
    Laboratory of Molecular Biology and Immunology, Department of Pharmacy, School of Health Sciences, University of Patras, Rion, 26504 Patras, Greece
    Clin Dev Immunol 2012:484919. 2012
  9. ncbi request reprint A single nucleotide polymorphism in the HBBP1 gene in the human β-globin locus is associated with a mild β-thalassemia disease phenotype
    Emily Giannopoulou
    Laboratory of Molecular Biology and Immunology, Department of Pharmacy, School of Health Sciences, University of Patras, University Campus, Rion, Patras, Greece
    Hemoglobin 36:433-45. 2012
  10. doi request reprint DruGeVar: an online resource triangulating drugs with genes and genomic biomarkers for clinical pharmacogenomics
    Eleni Dalabira
    Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece
    Public Health Genomics 17:265-71. 2014

Collaborators

  • George P Patrinos
  • Adamantia Papachatzopoulou
  • Konstantinos Lazaridis
  • Marianthi Georgitsi
  • George Lagoumintzis
  • Socrates J Tzartos
  • Zoi Zagoriti
  • Emmanouil Viennas
  • Giannis Tzimas
  • Marina Bartsakoulia
  • Christina Tafrali
  • Vassiliki Gkantouna
  • Emily Giannopoulou
  • Olga Giannakopoulou
  • Gregory Kordas
  • Dimitra Kalamida
  • Vassiliki A Gkantouna
  • Zafeiria Marina Ioannou
  • Manousos E Kambouris
  • Eleni Dalabira
  • Petros Papadopoulos
  • Athanasios Niarchos
  • Eleana F Stavrou
  • Alexandra Kourakli
  • John Tsaknakis
  • Fotios Ntellos
  • Nikolaos Dimitropoulos
  • Marios Zouridakis
  • Alexandros Sotiriadis
  • Sotiris Sideris
  • Michael Paraskevas
  • Giannis E Tzimas
  • Emmanouil S Viennas
  • Elisavet Daki
  • Cristiana Pavlidis
  • Abdelaziz Sefiani
  • Eirini Grapsa
  • Angeliki Komianou
  • Nikolaos Trakas
  • Sotirios Sideris
  • Paraskevi Zisimopoulou
  • Theodora Katsila
  • Ilham Ratbi
  • Branka Zukic
  • Sonja Pavlovic
  • Sjaak Philipsen
  • Joseph Borg
  • Milena Radmilovic
  • Arsinoi Paizi
  • Maja Stojiljkovic-Petrovic
  • Alexander E Felice
  • Polyxeni Lambropoulou
  • Vassilis Douris
  • Assimina Georgostathi
  • Kostas Iatrou
  • Maria Rigou
  • Marina Ioannou
  • Sjozef van Baal
  • Athanassia Boulakou
  • Georgios A Spyroulias
  • Christos T Chasapis
  • Elena Christodoulopoulou
  • Eva Kyriacou
  • Dimitris I Antoniou
  • Georgios A Dalkas
  • Emanuel F Petricoin
  • Athanasios Papakyriakou
  • Panagiota Vlahopoulou
  • Athanassios Tsakalidis
  • Efrosini Fostieri
  • Anastasia Sideri
  • Kalliopi Kostelidou
  • Vassiliki Avramopoulou

Detail Information

Publications18

  1. doi request reprint Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine
    Konstantinos Poulas
    Department of Pharmacy, University of Patras, GR 26500, Patras, Greece
    J Neuroimmunol 250:94-8. 2012
    ..In most patients with D-penicillamine-induced MG, anti-AChR antibodies are detected, but the presence of anti-MuSK antibodies has not been reported previously...
  2. doi request reprint Population-ethnic group specific genome variation allele frequency data: a querying and visualization journey
    Emmanouil Viennas
    Department of Computer Engineering and Informatics, University of Patras, Patras, Greece
    Genomics 100:93-101. 2012
    ....
  3. pmc Developments in FINDbase worldwide database for clinically relevant genomic variation allele frequencies
    Petros Papadopoulos
    Department of Pharmacy, School of Health Sciences, University of Patras, GR 26504, Patras, Greece, Department of Computer Engineering and Informatics, Faculty of Engineering, University of Patras, GR 26504, Patras, Greece, Faculty of Medicine and Pharmacy, Human Genomic Center, University Mohammed V Souissi, 11400, Rabat, Morocco and Department of Computer and Informatics Engineering, Technological Educational Institute of Western Greece, GR 26334, Patras, Greece
    Nucleic Acids Res 42:D1020-6. 2014
    ....
  4. pmc Recent advances in genetic predisposition of myasthenia gravis
    Zoi Zagoriti
    Laboratory of Molecular Biology and Immunology, Department of Pharmacy, School of Health Sciences, University of Patras, 26504 Rio, Patras, Greece
    Biomed Res Int 2013:404053. 2013
    ..Although the majority of these results have been derived from candidate gene studies, the focal point of all recent genetic studies is the first genome-wide association study (GWAS) conducted on early-onset MG patients. ..
  5. doi request reprint Scale up and safety parameters of antigen specific immunoadsorption of human anti-acetylcholine receptor antibodies
    George Lagoumintzis
    Department of Pharmacy, University of Patras, GR 26500, Patras, Greece
    J Neuroimmunol 267:1-6. 2014
    ..Thus, antigen-specific apheresis of anti-AChR autoantibodies seems a safe and effective treatment for myasthenia gravis that can be scaled up for clinical testing. ..
  6. doi request reprint Genomic variation in the MAP3K5 gene is associated with β-thalassemia disease severity and hydroxyurea treatment efficacy
    Christina Tafrali
    University of Patras, School of Health Sciences, Department of Pharmacy, University Campus, Rion, Patras, Greece
    Pharmacogenomics 14:469-83. 2013
    ..Furthermore, we examined MAP3K5 expression in the context of high fetal hemoglobin (HbF) and upon HU treatment in erythroid progenitor cells from healthy and KLF1 haploinsufficient individuals...
  7. doi request reprint Introducing dAUTObase: a first step towards the global scale geoepidemiology of autoimmune syndromes and diseases
    Vassiliki A Gkantouna
    Department of Computer Engineering and Informatics, University of Patras, Rio Patras, 26500, Greece, Department of Pharmacy, University of Patras, Rio Patras 26500, Greece, Department of Computer and Informatics Engineering, Technological Educational Institute of Western Greece, M Alexandrou 1, Koukouli Patras 26334, Greece
    Bioinformatics 31:581-6. 2015
    ..The initiation of a geoepidemiological database, for recording autoimmune incidents with a focus to clinical manifestations, demographic parameters and geographic background is crucial to detect correlations...
  8. pmc Genetics of myasthenia gravis: a case-control association study in the Hellenic population
    Zoi Zagoriti
    Laboratory of Molecular Biology and Immunology, Department of Pharmacy, School of Health Sciences, University of Patras, Rion, 26504 Patras, Greece
    Clin Dev Immunol 2012:484919. 2012
    ..As far as we are aware, this is the first worldwide attempt to address the possible association between IRF-5 and TNFAIP3 common genetic variants and the genetic basis of MG...
  9. ncbi request reprint A single nucleotide polymorphism in the HBBP1 gene in the human β-globin locus is associated with a mild β-thalassemia disease phenotype
    Emily Giannopoulou
    Laboratory of Molecular Biology and Immunology, Department of Pharmacy, School of Health Sciences, University of Patras, University Campus, Rion, Patras, Greece
    Hemoglobin 36:433-45. 2012
    ..Our data suggest that the rs2071348 polymorphism is associated with higher Hb F levels and a milder β-thal disease phenotype. However, the rs2071348 polymorphism in the HBBP1 gene does not correlate with response to HU treatment...
  10. doi request reprint DruGeVar: an online resource triangulating drugs with genes and genomic biomarkers for clinical pharmacogenomics
    Eleni Dalabira
    Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece
    Public Health Genomics 17:265-71. 2014
    ....
  11. pmc Expression of a highly antigenic and native-like folded extracellular domain of the human α1 subunit of muscle nicotinic acetylcholine receptor, suitable for use in antigen specific therapies for Myasthenia Gravis
    Athanasios Niarchos
    Department of Pharmacy, University of Patras, Patras, Greece
    PLoS ONE 8:e84791. 2013
    ..Our results indicate that i-α1-ECD is an improved protein for use in antigen-specific MG therapeutic strategies. ..
  12. ncbi request reprint Isolation and functional characterization of anti-acetylcholine receptor subunit-specific autoantibodies from myasthenic patients: receptor loss in cell culture
    Sotiris Sideris
    Department of Pharmacy, University of Patras, 26504 Patras, Greece
    J Neuroimmunol 189:111-7. 2007
    ....
  13. pmc Direct proof of the in vivo pathogenic role of the AChR autoantibodies from myasthenia gravis patients
    Gregory Kordas
    Department of Pharmacy, University of Patras, Patras, Greece
    PLoS ONE 9:e108327. 2014
    ....
  14. doi request reprint Population-specific documentation of pharmacogenomic markers and their allelic frequencies in FINDbase
    Marianthi Georgitsi
    Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece
    Pharmacogenomics 12:49-58. 2011
    ....
  15. pmc FINDbase: a worldwide database for genetic variation allele frequencies updated
    Marianthi Georgitsi
    Department of Pharmacy, School of Health Sciences, Faculty of Engineering, University of Patras, Patras, Greece
    Nucleic Acids Res 39:D926-32. 2011
    ....
  16. ncbi request reprint Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity
    Dimitra Kalamida
    Department of Pharmacy, University of Patras, Rio Patras, Greece
    FEBS J 274:3799-845. 2007
    ..Here, we review some of the latest advances in our understanding of nAChRs and their involvement in physiology and pathology...
  17. ncbi request reprint Genetic databases and their potential in pharmacogenomics
    George Lagoumintzis
    Department of Pharmacy, University of Patras, Patras, Greece
    Curr Pharm Des 16:2224-31. 2010
    ..Moreover, the key elements that are holding back the field as well as the challenges that should be addressed in the near future are also commented...
  18. doi request reprint A computational investigation on the role of glycosylation in the binding of alpha1 nicotinic acetylcholine receptor with two alpha-neurotoxins
    Nikolaos Dimitropoulos
    Department of Pharmacy, University of Patras, GR 26504, Patras, Greece
    Proteins 79:142-52. 2011
    ..Analysis of the predicted residue-specific intermolecular interactions is intended to inspire biophysical studies on the functional role of glycosylation in the gating mechanism...