Research Topics
| George PanosSummaryAffiliation: University of Patras School of Medicine, Patras University General Hospital Location: Patras, Greece Summary: Assistant Professor in Internal Medicine & Infectious Diseases Internal Medicine Infectious Diseases Including: Tropical Medicine HIV Medicine Hepatitis Biomedical Engineering and Computing Publications
| Collaborators
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Detail Information
Publications
Fatal and nonfatal AIDS and non-AIDS events in HIV-1-positive individuals with high CD4 cell counts according to viral load strataJoanne Reekie
University College London Medical School, London, UK
AIDS 25:2259-68. 2011..9 copies/ml) and high (≥ 10000 copies/ml)...
Death rates in HIV-positive antiretroviral-naive patients with CD4 count greater than 350 cells per microL in Europe and North America: a pooled cohort observational studyRebecca K Lodwick
HIV Epidemiology and Biostatistics Group, Research Department of Infection and Population Health, UCL Medical School, Royal Free Campus, London, UK
Lancet 376:340-5. 2010..We aimed to examine this by analysis of pooled data from industrialised countries...- Effect of meteorological variables on the incidence of respiratory tract infectionsMatthew E Falagas
Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
Respir Med 102:733-7. 2008..The possible effect of the various meteorological variables on the incidence of upper and lower respiratory tract infections (RTIs) has intrigued the scientific community for decades... - Prevalence of genotypic resistance to nucleoside analogues, nonnucleoside analogues, and protease inhibitors in HIV-infected persons in Athens, GreeceGeorge Panos
HIV Unit, 1st IKA Hospital, Athens, Greece
AIDS Res Hum Retroviruses 24:43-51. 2008..M184V (63.6%) and K103N (25.2%) were the most frequent mutations related to NRTIs and NNRTIs, respectively... - Albendazole versus praziquantel in the treatment of neurocysticercosis: a meta-analysis of comparative trialsDimitrios K Matthaiou
Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
PLoS Negl Trop Dis 2:e194. 2008..We investigated the role of albendazole and praziquantel in the treatment of patients with parenchymal neurocysticercosis by performing a meta-analysis of comparative trials of their effectiveness and safety... - Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimenZoe Fox
Copenhagen HIV Programme, University of Copenhagen Rigshospitalet, Copenhagen, Denmark
AIDS 22:2279-89. 2008..Limited data exist to guide clinical practice on the best interruption strategy to use... - Loss to follow-up in an international, multicentre observational studyA Mocroft
Royal Free and University College Medical School, London, UK
HIV Med 9:261-9. 2008..The aim of this work was to assess loss to follow-up (LTFU) in EuroSIDA, an international multicentre observational cohort study... - Changes over time in risk factors for cardiovascular disease and use of lipid-lowering drugs in HIV-infected individuals and impact on myocardial infarctionC A Sabin
Dept of Primary Care and Population Sciences, Royal Free and UC Medical School, Rowland Hill St, London, NW3 2PF, United Kingdom
Clin Infect Dis 46:1101-10. 2008..We evaluated changes in risk factors for CVD and the use of lipid-lowering therapy in HIV-infected individuals and assessed the impact of any changes on the incidence of myocardial infarction... 
Mortality and morbidity of HIV infected patients receiving HAART: a cohort studyGeorge Panos
HIV Unit, 1st IKA Hospital, Athens, Greece
Curr HIV Res 6:257-60. 2008..Our data from the studied cohort adds to the relevant literature regarding the dramatic reduction of morbidity and mortality that occurred after the availability of HAART...- Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART studySean Emery
Therapeutic and Vaccine Research Program, National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, 376 Victoria St, Sydney, NSW 2010, Australia
J Infect Dis 197:1133-44. 2008..In the DC group, participants started ART when the CD4+ cell count was <250 cells/microL. Clinical outcomes in participants not receiving ART at entry inform the early use of ART... - Predicting the risk of cardiovascular disease in HIV-infected patients: the data collection on adverse effects of anti-HIV drugs studyNina Friis-Møller
Copenhagen HIV Programme CHIP, University of Copenhagen Faculty of Health Science, Copenhagen, Denmark
Eur J Cardiovasc Prev Rehabil 17:491-501. 2010..Furthermore, exposures to some antiretroviral drugs seem to be independently associated with increased CVD risk. We aimed to develop cardiovascular risk-assessment models tailored to HIV-infected patients... - Transmitted drug resistant HIV-1 and association with virologic and CD4 cell count response to combination antiretroviral therapy in the EuroSIDA StudyWendy P Bannister
Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
J Acquir Immune Defic Syndr 48:324-33. 2008..To investigate prevalence of transmitted drug-resistant human immunodeficiency virus (TDR) and factors associated with TDR and to compare virological and CD4 count response to combination antiretroviral therapy... - Fungal infection as a risk factor for HIV disease progression among patients with a CD4 count above 200/microl in the era of cARTDaria Podlekareva
Copenhagen HIV Programme, University of Copenhagen, Faculty of Health Sciences, Denmark
Scand J Infect Dis 40:908-13. 2008..FI can be used as a clinical marker for disease progression and indirect indicator for initiation/changing cART in settings where laboratory facilities are limited... - Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patientsAmanda Mocroft
HIV Epidemiology and Biostatistics Group, Research Department of Infection and Population Health, Division of Population Health, University College London Medical School, Royal Free Campus, London, UK
AIDS 24:1667-78. 2010..Chronic kidney disease (CKD) in HIV-positive persons might be caused by both HIV and traditional or non-HIV-related factors. Our objective was to investigate long-term exposure to specific antiretroviral drugs and CKD... - Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaborationCaroline A Sabin
Lancet 371:1417-26. 2008..The excess risk does not seem to be explained by underlying established cardiovascular risk factors and was not present beyond 6 months after drug cessation... - Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trialW M El-Sadr
Ann Intern Med 149:289-99. 2008..Episodic antiretroviral therapy, as used in the SMART study, should be avoided... - Does less frequent routine monitoring of patients on a stable, fully suppressed cART regimen lead to an increased risk of treatment failure?Joanne Reekie
HIV Epidemiology and Biostatistics Group, Research Department of Infection and Population Health, Royal Free and University College Medical School, London, UK
AIDS 22:2381-90. 2008..To investigate whether HIV-infected patients on a stable and fully suppressive combination antiretroviral therapy (cART) regimen could safely be monitored less often than the current recommendations of every 3 months... - Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settingsAlessandro Cozzi-Lepri
Research Department of Infection and Population Health, Royal Free and University College Medical School, London, United Kingdom
J Infect Dis 200:687-97. 2009.... - Systematic review: are antibiotics detrimental or beneficial for the treatment of patients with Escherichia coli O157:H7 infection?G Z Panos
Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
Aliment Pharmacol Ther 24:731-42. 2006..Escherichia coli O157:H7 is a foodborne pathogen causing haemorrhagic colitis, which is sometimes complicated by haemolytic uraemic syndrome or thrombotic thrombocytopenic purpura... - A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapyRoger Paredes
Institut de Recerca de la SIDA IrsiCaixa, Spain
J Infect Dis 204:741-52. 2011..The clinical relevance of mutations in the connection subdomain and the ribonuclease (RNase) H domain of HIV-1 reverse transcriptase (RT) is uncertain... - Hepatitis C virus coinfection does not influence the CD4 cell recovery in HIV-1-infected patients with maximum virologic suppressionLars Peters
Copenhagen HIV Programme, University of Copenhagen, Copenhagen, Denmark
J Acquir Immune Defic Syndr 50:457-63. 2009..Conflicting data exist whether hepatitis C virus (HCV) affects the CD4 cell recovery in patients with HIV starting antiretroviral treatment... - Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA studyE Florence
Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
HIV Med 4:255-62. 2003..To describe the prevalence and risk factors of poor CD4 count rise despite a good virological response on highly active antiretroviral treatment (HAART)... - Multi-skeletal Pneumocystis jiroveci (carinii) in an HIV-seropositive patientGeorge Z Panos
1st IKA Hospital, Penteli, Athens, Greece
Int J STD AIDS 18:134-7. 2007..jiroveci infection in an HIV-seropositive patient, with multiple skeletal lesions, especially in the skull and in vertebrae region, and concomitant non-small-cell lung cancer, with a very poor prognosis... - Helicobacter pylori infection in symptomatic HIV-seropositive and -seronegative patients: a case-control studyGeorge Z Panos
First IKA Hospital, Athens, Greece
AIDS Res Hum Retroviruses 23:709-12. 2007..06). The grading of the density of H. pylori infection and the grading of the histomorphological findings according to the Sydney classification were similar between HIV-seropositive and -seronegative patients with H. pylori infection... - Risk of discontinuation of nevirapine due to toxicities in antiretroviral-naive and -experienced HIV-infected patients with high and low CD4+ T-cell countsAmanda Mocroft
Royal Free and University College Medical School, London, UK
Antivir Ther 12:325-33. 2007.... - High prevalence of the metabolic syndrome in HIV-infected patients: impact of different definitions of the metabolic syndromeSigne W Worm
Copenhagen HIV Programme, University of Copenhagen, Copenhagen, Denmark
AIDS 24:427-35. 2010.... - Effects of nandrolone decanoate compared with placebo or testosterone on HIV-associated wastingJ Gold
The Albion Street Centre, Surry Hills, NSW, Australia
HIV Med 7:146-55. 2006..Nandrolone decanoate treatment resulted in greater increases in fat-free mass than placebo and demonstrated a trend for a significant increase when compared with testosterone... - A meta-analysis of transient elastography for the detection of hepatic fibrosisJustin Stebbing
Department of HIV Medicine, Chelsea and Westminster Hospital, St Stephen s Centre, Imperial College School of Medicine, London, UK
J Clin Gastroenterol 44:214-9. 2010..We performed a meta-analysis to further assess its use in comparison with liver biopsy... - Predictors of hepatitis B virus genotype and viraemia in HIV-infected patients with chronic hepatitis B in EuropeVincent Soriano
Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
J Antimicrob Chemother 65:548-55. 2010..Information about factors determining HBV genotype distribution and viraemia in HIV/HBV-co-infected patients is scarce... - History of viral suppression on combination antiretroviral therapy as a predictor of virological failure after a treatment changeJ Reekie
Research Department of Infection and Population Health, University College London Medical School, UK
HIV Med 11:469-78. 2010..The relationship between such differences and risk of virological failure after starting a new antiretroviral could help with patient monitoring strategies... - Human herpesvirus 6-related pure red cell aplasia, secondary graft failure, and clinical severe immune suppression after allogeneic hematopoietic cell transplantation successfully treated with foscarnetE D Lagadinou
Department of Internal Medicine, Patras University Medical Center, Rio Patras, Greece
Transpl Infect Dis 12:437-40. 2010..Late bone marrow aplasia and late severe infections after allo-HCT without other obvious causes may be HHV-6 related... - Relationship between current level of immunodeficiency and non-acquired immunodeficiency syndrome-defining malignanciesJoanne Reekie
University College London Medical School, London, UK
Cancer 116:5306-15. 2010..However, conflicting data have been reported on the relationship between immunodeficiency and the development of some non-AIDS-defining malignancies... - Serious fatal and nonfatal non-AIDS-defining illnesses in EuropeAmanda Mocroft
Research Department of Infection and Population Health, University College Medical School, London, UK
J Acquir Immune Defic Syndr 55:262-70. 2010..Little is known about the incidence and risk factors for serious non-AIDS-defining events... - Dialysis and renal transplantation in HIV-infected patients: a European surveyJoan Carles Trullàs
Department of Internal Medicine, Hosp Sant Jaume, Olot, Girona, Spain
J Acquir Immune Defic Syndr 55:582-9. 2010..To determine prevalence and characteristics of end-stage renal diseases (ESRD) [dialysis and renal transplantation (RT)] among European HIV-infected patients... - A comparison of the long-term durability of nevirapine, efavirenz and lopinavir in routine clinical practice in Europe: a EuroSIDA studyJ Reekie
Research Department of Infection and Population Health, University College London Medical School, Royal Free Campus, London, UK
HIV Med 12:259-68. 2011..The aim of this analysis was to compare the durability of nevirapine, efavirenz and lopinavir regimens based on these measures... - A standardized algorithm for determining the underlying cause of death in HIV infection as AIDS or non-AIDS related: results from the EuroSIDA studyJustyna D Kowalska
Copenhagen HIV Programme, University of Copenhagen, Copenhagen, Denmark
HIV Clin Trials 12:109-17. 2011.... - Dealing with the substance abuse epidemic and infective endocarditis: clinical, immunologic and pathogenetic aspectsIoannis Starakis
Department of Internal Medicine, Patras University Hospital
Curr Vasc Pharmacol 10:247-56. 2012..Our aim is to comprehensively review the clinical features and complications and also the possible pathogenetic and immunologic mechanisms implicated in IE patients who are injecting illicit substances... - Long-term exposure to combination antiretroviral therapy and risk of death from specific causes: no evidence for any previously unidentified increased risk due to antiretroviral therapyJustyna D Kowalska
Copenhagen HIV Programme, University of Copenhagen, Denmark
AIDS 26:315-23. 2012..Therefore we investigated changes in the rate of death with increasing exposure to cART... - Activation and coagulation biomarkers are independent predictors of the development of opportunistic disease in patients with HIV infectionAlison J Rodger
HIV Epidemiology and Biostatistics Group, Research Dept of Infection and Population Health, UCL Medical School, University College London, London, UK
J Infect Dis 200:973-83. 2009..Their associations with opportunistic disease (OD) in human immunodeficiency virus (HIV)-positive patients were examined... - Increasing prevalence of HIV-1 subtype A in Greece: estimating epidemic history and originDimitrios Paraskevis
Department of Hygiene and Epidemiology, National Retrovirus Reference Center, Athens, Greece
J Infect Dis 196:1167-76. 2007..In North America and Europe, human immunodeficiency virus (HIV)-1 infection has typically been dominated by subtype B transmission. More recently, however, non-B subtypes have been increasingly reported in Europe... - Infectious disease cases for educational purposes: open-access resources on the InternetMatthew E Falagas
Alfa Institute of Biomedical Sciences, 1st IKA Hospital, Athens, Greece
Clin Infect Dis 45:495-500. 2007.... - Lamivudine and famciclovir treatment in HIV patients with acute hepatitis B virus infection and hepatitis B reactivationGeorge Z Panos
J Clin Gastroenterol 41:222-3. 2007 - Impact of initial discordant treatment with beta-lactam antibiotics on clinical outcomes in adults with pneumococcal pneumonia: a systematic reviewMatthew E Falagas
Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos St, 151 23 Marousi, Athens, Greece
Mayo Clin Proc 81:1567-74. 2006..To systematically examine the available evidence regarding the effect of initial discordant therapy with beta-lactam antibiotics on mortality, clinical success, and bacteriological eradication in patients with pneumococcal pneumonia... - Implications of findings of bibliometric analyses in parasitologyMatthew E Falagas
Trends Parasitol 23:12-3. 2007 - Prevalence of resistance-associated mutations in newly diagnosed HIV-1 patients in GreeceD Paraskevis
Department of Hygiene and Epidemiology, Athens University Medical School, Mikras Asias 75, GR 11527 Athens, Greece
Virus Res 112:115-22. 2005..For two individuals, there was clear evidence for transmitted resistance based on epidemiological information for a known source of HIV-1 transmission. The prevalence of the HIV-1 non-B subtypes and recombinants was 52%... - Predictors of immunological failure after initial response to highly active antiretroviral therapy in HIV-1-infected adults: a EuroSIDA studyUlrik Bak Dragsted
Hvidovre University Hospital, Copenhagen, Denmark
J Infect Dis 190:148-55. 2004..Factors that determine the immunological response to highly active antiretroviral therapy (HAART) are poorly defined... - The role of antiretroviral therapy in the incidence of pancreatitis in HIV-positive individuals in the EuroSIDA studyColette J Smith
Royal Free and University College Medical School, London, UK
AIDS 22:47-56. 2008..This study investigated the incidence of pancreatitis and its association with antiretroviral therapy (ART), focussing on stavudine and didanosine... - Socioeconomic status (SES) as a determinant of adherence to treatment in HIV infected patients: a systematic review of the literatureMatthew E Falagas
Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
Retrovirology 5:13. 2008..Thus, we sought to perform a systematic review of the evidence regarding the association of SES with adherence to treatment of patients with HIV/AIDS... - Interruption of antiretroviral therapy is associated with increased plasma cystatin CAmanda Mocroft
University College London Medical School, London, UK
AIDS 23:71-82. 2009.... - The EuroSIDA study: Regional differences in the HIV-1 epidemic and treatment response to antiretroviral therapy among HIV-infected patients across Europe--a review of published resultsDaria Podlekareva
Copenhagen HIV Programme, University of Copenhagen, Denmark
Cent Eur J Public Health 16:99-105. 2008..Strategies include creating scientific collaborations for HIV clinicians as well as teaching clinicians about the most advanced HIV management at clinically oriented courses held in eastern Europe... - HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignanciesAntonella D arminio Monforte
Dipartimento di Medicina, Chirurgia e Odontoiatria, Clinica di Malattie Infettive e Tropicali, Azienda Ospedaliera Polo Universitario San Paolo, via A Di Rudinì 8 20142 Milano, Italy
AIDS 22:2143-53. 2008..To evaluate deaths from AIDS-defining malignancies (ADM) and non-AIDS-defining malignancies (nADM) in the D:A:D Study and to investigate the relationship between these deaths and immunodeficiency... - Spontaneous viral clearance, viral load, and genotype distribution of hepatitis C virus (HCV) in HIV-infected patients with anti-HCV antibodies in EuropeVincent Soriano
Service of Infectious Diseases, Hospital Carlos III, Madrid, Spain
J Infect Dis 198:1337-44. 2008.... - Prolonged survival of an HIV-infected patient with plasmablastic lymphoma of the oral cavityGeorge Panos
HIV Unit, 2nd Internal Medicine Clinic, 1st IKA Hospital, Athens, Greece
Am J Hematol 82:761-5. 2007..The patient remains in complete remission 61 months after the diagnosis of plasmablastic lymphoma... - Transient elastography, liver stiffness values, and acute hepatopathyGeorge Panos
Hepatology 47:2140; author reply 2141. 2008 - Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-upJens D Lundgren
Copenhagen HIV Programme CHIP, Faculty of Health Sciences, University of Copenhagen, Panum Institute, 2200 Copenhagen N, Denmark
J Infect Dis 197:1145-55. 2008..Rates and predictors of opportunistic disease or death (OD/death) and the relative risk (RR) in DC versus VS groups according to the latest CD4+ cell count and HIV RNA level are reported... - Influence of age on CD4 cell recovery in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy: evidence from the EuroSIDA studyJ P Viard
Service d immunologie clinique, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, Paris, France
J Infect Dis 183:1290-4. 2001..Time to a CD4 increase of >200x106 cells/L was shorter for patients in the younger age groups (P=.0026), as confirmed by multivariate analysis (P<10-4). Younger age may favor CD4 cell restoration because of preserved thymic function...