Research Topics
Species | Anna D PananiSummaryAffiliation: University of Athens Country: Greece Publications
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Detail Information
Publications
Isochromosome 5p, a novel recurrent abnormality in breast cancer: is it a common abnormality in cancer?Anna D Panani
Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
In Vivo 24:715-7. 2010..Isochromosome i(5p) is a frequent finding in several types of cancer but it has been rarely described in breast cancer. The aim of the present study was to investigate the presence of i(5p) in primary breast tumors...
Cytogenetic findings in adult greek myelodysplastic syndrome patients: predominance of single trisomy 8Anna D Panani
The Critical Care Department, Medical School of Athens University, Research Unit, Evangelismos Hospital, Athens, Greece
In Vivo 20:115-8. 2006..The most common single anomaly was trisomy 8, while a relatively high incidence of an isolated +14 was also observed. Notably, this is the first time an isolated i(1q) has been described in the literature...
Sex chromosome abnormalities in bladder cancer: Y polysomies are linked to PT1-grade III transitional cell carcinomaAnna D Panani
Critical Care Department, Medical School of Athens University, Research Unit, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Anticancer Res 26:319-23. 2006....
Is aneusomy of chromosome 9 alone a valid biomarker for urinary bladder cancer screening?Anna D Panani
Critical Care Department, Medical School of Athens University, Research Unit, Evangelismos Hospital, Athens 10676, Greece
Anticancer Res 26:1161-5. 2006..The purpose of the present study was to investigate whether chromosome 9 aneusomy alone is a valid, cost effective, biomarker for bladder cancer screening...
Gain of an isochromosome 5p: a rare recurrent abnormality in acute myeloid leukemiaAnna D Panani
The Critical Care Department, Medical School of Athens University, Research Unit, Evangelismos Hospital, Athens, Greece
In Vivo 20:359-60. 2006..The cytogenetic findings supported the hypothesis that i(5p) may represent a primary abnormality, which characterizes a small subset of AML cases...
Cytogenetic findings in untreated patients with essential thrombocythemiaAnna D Panani
The Critical Care Department, Medical School of Athens University, Research Unit, Evangelismos Hospital, Athens, Greece
In Vivo 20:381-4. 2006..The documentation of more cases of chromosomal abnormalities in ET at the time of diagnosis may facilitate the identification of candidate genes involved in the neoplastic process...
Cytogenetic and molecular aspects of Philadelphia negative chronic myeloproliferative disorders: clinical implicationsAnna D Panani
Critical Care Department, Research Unit, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens, Greece
Cancer Lett 255:12-25. 2007..This finding represents the most important advance in understanding of the molecular mechanisms underlined the pathogenesis of CMPD, contributing to the classification and management of patients...
Preferential involvement of chromosome 11 as add(11)(p15) in ovarian cancer: is it a common cytogenetic abnormality in cancer?Anna D Panani
Critical Care Department, Medical School of Athens University, Cytogenetics Unit, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 258:262-7. 2007..Improving the molecular understanding of ovarian cancer development and progression could facilitate the detection of specific tumor subtypes and contribute also to novel strategies for the management of ovarian cancer patients...
Single chromosomal abnormalities in Philadelphia-negative chronic myeloproliferative disordersAnna D Panani
The Critical Care Department, Medical School of Athens University, Cytogenetics Unit, Evangelismos Hospital, Athens, Greece
In Vivo 21:867-70. 2007..The aim of this study was to investigate the frequency and the type of single chromosomal changes in Philadelphia-negative CMPD patients...
Is there an association with constitutional structural chromosomal abnormalities and hematologic neoplastic process? A short reviewAnna D Panani
Critical Care Department, Medical School of Athens University, Epsilonvangelismos Hospital, Ipsilandou 45 47, Athens 106 76, Greece
Ann Hematol 88:293-9. 2009..Regarding constitutional anomalies in patients with hematologic disorders, a survey of the cytogenetic data of our cytogenetics unit is herein also presented...
Janus kinase 2 mutations in Philadelphia negative chronic myeloproliferative disorders: clinical implicationsAnna D Panani
Critical Care Department, Cytogenetics Unit, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 284:7-14. 2009..Furthermore, the discovery of JAK2 mutations facilitated the development of new targeted therapies and clinical trials are currently ongoing...
Simple structural chromosomal abnormalities in advanced stage of ovarian cancerAnna D Panani
The Critical Care Department, University of Athens Medical School, Athens, Greece
In Vivo 23:425-8. 2009..Since single chromosomal changes might be primary events implicated in the initiation of the neoplastic process, the aim of the present study was to investigate the presence of simple structural chromosomal changes in ovarian cancer...
Numerical abnormalities of chromosome 9 and p16CDKN2A gene deletion detected by FISH in non-small cell lung cancerAnna D Panani
Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 106 76, Greece
Anticancer Res 29:4483-7. 2009....
Hidden chromosome 8 abnormalities detected by FISH in adult primary myelodysplastic syndromesAnna D Panani
Critical Care Department, Medical School of Athens University, Research Unit, Evangelismos Hospital, Athens, Greece
In Vivo 19:979-81. 2005..However, a large number of metaphases, even those of poor quality, must be analyzed in each case. The FISH technique could be considered to be complementary to achieve a more accurate analysis...
Cytogenetic and molecular aspects of lung cancerAnna D Panani
Critical Care Department, Research Unit, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 239:1-9. 2006..Further research is required in order to systematically investigate genetical alterations in lung cancer contributing to improvement of lung cancer classification and staging and to development of new molecular targeted therapies...
Non-random structural chromosomal changes in primary gastric cancerAnna D Panani
Critical Care Department, Research Unit, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 225:291-5. 2005..Conventional cytogenetics continues to be valuable in cancer study detecting genomic areas potentially candidate for the isolation of genes related to carcinogenesis...
Numerical aberrations of chromosome 8 in gastric cancer detected by fluorescence in situ hybridizationAnna D Panani
The Second Department of Internal Medicine Propaedeutic, Research Unit, Athens University, Evangelismos Hospital, Athens, Greece
Anticancer Res 24:155-9. 2004..The aim of our study was to evaluate the numerical aberrations of chromosome 8 in gastric cancer using fluorescence in situ hybridization (FISH)...
Deletion (11)(q13) as the sole anomaly in myeloid malignancies: four new cases and a short reviewAnna D Panani
Second Department of Internal Medicine Propaedeutic, Research Unit of Athens University, Evangelismos Hospital, 10676, Athens, Greece
Ann Hematol 83:153-5. 2004..Summarizing the literature, only ten other cases of myeloid malignancies with deletion of 11q involving band q13 as the sole anomaly have been reported. All but one of these cases presented interstitial deletions...
Novel constitutional translocations t(3;5)(p25;q22) and t(1;14)(p31;q21) in patients with acute leukemiaAnna D Panani
Second Department of Internal Medicine Propaedeutic, Research Unit of the University of Athens, Evangelismos Hospital, Ipsilandou 45 47, 10676, Athens, Greece
Ann Hematol 83:156-9. 2004..To our knowledge, none of the above translocations has been previously reported...
Novel recurrent structural chromosomal aberrations in primary bladder cancerAnna D Panani
The Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece
Anticancer Res 24:2967-74. 2004..The aim of this study was to investigate recurrent structural chromosomal aberrations with common breakpoints and to correlate them with the histological stage of tumors...
Numerical aberrations of chromosomes 9 and 11 detected by FISH in Greek bladder cancer patientsAnna D Panani
Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece
Anticancer Res 24:3857-61. 2004..The aim of this study was to evaluate, by FISH technique, the numerical aberrations of chromosomes 9 and 11 in Greek bladder cancer patients and to correlate them with grade and histological stage of the tumors...
Cytogenetic data as a prognostic factor in multiple myeloma patients: involvement of 1p12 region an adverse prognostic factorAnna D Panani
Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece
Anticancer Res 24:4141-6. 2004..Among known prognostic factors the cytogenetic abnormalities are thought to be of major importance. The aim of this study was to correlate certain chromosomal abnormalities with immunoglobulin isotype and survival in MM patients...
Perinuclear antineutrophil cytoplasmic antibody myeloperoxidase-positive vasculitis in association with ulcerative colitisAnna D Panani
Critical Care Department, Evangelismos Hospital, Medical School of Athens University, Ipsilantou 45 47, Athens, 10676, Greece
Clin Rheumatol 25:35-7. 2006..The possible causative association between the UC, the p-ANCA-MPO-positive small vessel vasculitis, and the anticardiolipin antibodies is discussed...
Non-random structural chromosomal changes in ovarian cancer: i(5p) a novel recurrent abnormalityAnna D Panani
Critical Care Department, Research Unit, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 235:130-5. 2006..Conventional cytogenetics continues to be valuable detecting the presence of non-random chromosomal breakpoints and facilitating the identification of genes implicated in tumorigenesis...
Cytogenetic aspects of adult primary myelodysplastic syndromes: clinical implicationsAnna D Panani
Critical Care Department, Research Unit, Medical School of Athens University, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 235:177-90. 2006....
Application of multiplex fluorescence in situ hybridization in the cytogenetic analysis of primary gastric carcinomaMaria I Stamouli
Second Department of Internal Medicine Propaedeutic, Athens University, Evangelismos Hospital, Athens, Greece
Cancer Genet Cytogenet 135:23-7. 2002..This study shows that M-FISH is valuable in identifying hidden structural abnormalities and could, therefore, be useful in the investigation of primary solid tumors...
Detection of genetic alterations in primary bladder carcinoma with dual-color and multiplex fluorescence in situ hybridizationMaria I Stamouli
Second Department of Internal Medicine-Propaedeutic, Research Unit, University of Athens, Evangelismos Hospital, Ipsilantou 45-47, Athens 10676, Greece
Cancer Genet Cytogenet 149:107-13. 2004..The TCC case also exhibited structural abnormalities of chromosome 9, resulting in loss of 9q. The combined G-banding and M-FISH findings could help reveal regions potentially involved in bladder tumorigenesis...
Cytogenetic and molecular aspects of gastric cancer: clinical implicationsAnna D Panani
Critical Care Department, Medical School of Athens University, Cytogenetics Unit, Evangelismos Hospital, Ipsilandou 45 47, Athens 10676, Greece
Cancer Lett 266:99-115. 2008..Also, based on molecular data identified in gastric cancer novel therapeutics might help to improve the treatment of this disease...
M-FISH in gastric lymphomaAngeliki D Ferti
Department of Internal Medicine, Sotiria Hospital, Messogion 152, Athens 11527, Greece
Cancer Genet Cytogenet 155:63-6. 2004..To our knowledge, cytogenetic data for gastric Burkitt-like lymphoma have not been reported, and M-FISH has not previously been used in the study of gastric lymphomas...
Molecular cytogenetic analysis of breast cancer: a combined multicolor fluorescence in situ hybridization and G-banding study of uncultured tumor cellsAngeliki D Ferti
Department of Internal Medicine, Sotiria Hospital, Messogion 152, Athens 11527, Greece
Cancer Genet Cytogenet 149:28-37. 2004..With the combination of G-banding and M-FISH techniques, chromosome misclassification is avoided and the characterization of complex tumor karyotypes is more effective...
