Paraskevi Moutsatsou

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint Glucocorticoid receptor, nuclear factor kappaB, activator protein-1 and C-jun N-terminal kinase in systemic lupus erythematosus patients
    Olga Oikonomidou
    Department of Biological Chemistry, University of Athens Medical School, Goudi, Athens, Greece
    Neuroimmunomodulation 13:194-204. 2006
  2. ncbi request reprint Deoxybenzoins are novel potent selective estrogen receptor modulators
    Zoi Papoutsi
    Department of Biological Chemistry, Medical School, University of Athens, 75 Mikras Asias Street, Goudi 11527, Athens, Greece
    Steroids 72:693-704. 2007
  3. pmc Estrogen receptor signaling and its relationship to cytokines in systemic lupus erythematosus
    E Kassi
    Department of Biological Chemistry, Medical School, University of Athens, Goudi, 11527 Athens, Greece
    J Biomed Biotechnol 2010:317452. 2010
  4. ncbi request reprint Molecular analysis of the estrogen receptor alpha gene in men with coronary artery disease: association with disease status
    Dimitrios Evangelopoulos
    Department of Biological Chemistry, Medical School, National University of Athens, 75 M Asias str, Goudi, 115 27, Athens, Greece
    Clin Chim Acta 331:37-44. 2003
  5. pmc Fatty acids derived from royal jelly are modulators of estrogen receptor functions
    Paraskevi Moutsatsou
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    PLoS ONE 5:e15594. 2010
  6. ncbi request reprint The glucocorticoid receptor signalling in breast cancer
    Paraskevi Moutsatsou
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    J Cell Mol Med 12:145-63. 2008
  7. ncbi request reprint The spectrum of phytoestrogens in nature: our knowledge is expanding
    Paraskevi Moutsatsou
    Department of Biological Chemistry, Athens University Medical School, Athens, Greece
    Hormones (Athens) 6:173-93. 2007
  8. ncbi request reprint Acteoside and martynoside exhibit estrogenic/antiestrogenic properties
    Zoi Papoutsi
    Department of Biological Chemistry, Medical School, University of Athens, 75 Mikras Asias Str, Goudi 11527, Athens, Greece
    J Steroid Biochem Mol Biol 98:63-71. 2006
  9. doi request reprint Beta-sitosterol exhibits anti-inflammatory activity in human aortic endothelial cells
    Stella Loizou
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    Mol Nutr Food Res 54:551-8. 2010
  10. ncbi request reprint Evaluation of estrogenic/antiestrogenic activity of ellagic acid via the estrogen receptor subtypes ERalpha and ERbeta
    Zoi Papoutsi
    Department of Biological Chemistry, Medical School, University of Athens Mikras Asias Str 75, Goudi, Athens 11527, Greece
    J Agric Food Chem 53:7715-20. 2005

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Glucocorticoid receptor, nuclear factor kappaB, activator protein-1 and C-jun N-terminal kinase in systemic lupus erythematosus patients
    Olga Oikonomidou
    Department of Biological Chemistry, University of Athens Medical School, Goudi, Athens, Greece
    Neuroimmunomodulation 13:194-204. 2006
    ....
  2. ncbi request reprint Deoxybenzoins are novel potent selective estrogen receptor modulators
    Zoi Papoutsi
    Department of Biological Chemistry, Medical School, University of Athens, 75 Mikras Asias Street, Goudi 11527, Athens, Greece
    Steroids 72:693-704. 2007
    ....
  3. pmc Estrogen receptor signaling and its relationship to cytokines in systemic lupus erythematosus
    E Kassi
    Department of Biological Chemistry, Medical School, University of Athens, Goudi, 11527 Athens, Greece
    J Biomed Biotechnol 2010:317452. 2010
    ..Results regarding the possible correlation between estrogen receptor gene polymorphisms and quantitative changes in the receptor protein to SLE pathology and cytokine production are reviewed...
  4. ncbi request reprint Molecular analysis of the estrogen receptor alpha gene in men with coronary artery disease: association with disease status
    Dimitrios Evangelopoulos
    Department of Biological Chemistry, Medical School, National University of Athens, 75 M Asias str, Goudi, 115 27, Athens, Greece
    Clin Chim Acta 331:37-44. 2003
    ..This region has not been studied in atherosclerotic disease. In the present study, we examined the association between coronary artery disease (CAD) and alterations of the NH(2)-terminal part of ERalpha coding region...
  5. pmc Fatty acids derived from royal jelly are modulators of estrogen receptor functions
    Paraskevi Moutsatsou
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    PLoS ONE 5:e15594. 2010
    ....
  6. ncbi request reprint The glucocorticoid receptor signalling in breast cancer
    Paraskevi Moutsatsou
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    J Cell Mol Med 12:145-63. 2008
    ....
  7. ncbi request reprint The spectrum of phytoestrogens in nature: our knowledge is expanding
    Paraskevi Moutsatsou
    Department of Biological Chemistry, Athens University Medical School, Athens, Greece
    Hormones (Athens) 6:173-93. 2007
    ..Evidently, phytoestrogen supplementation should be viewed with caution until further studies satisfactorily delineate the effects of individual phytoestrogens on human health and disease...
  8. ncbi request reprint Acteoside and martynoside exhibit estrogenic/antiestrogenic properties
    Zoi Papoutsi
    Department of Biological Chemistry, Medical School, University of Athens, 75 Mikras Asias Str, Goudi 11527, Athens, Greece
    J Steroid Biochem Mol Biol 98:63-71. 2006
    ..Our study suggests that the nature is rich in selective ERalpha and ERbeta ligands, the discovery of which may lead to the development of novel neutraceutical agents...
  9. doi request reprint Beta-sitosterol exhibits anti-inflammatory activity in human aortic endothelial cells
    Stella Loizou
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    Mol Nutr Food Res 54:551-8. 2010
    ..This study extends existing data regarding the cardioprotective effect of beta-sitosterol and provides new insights into understanding the molecular mechanism underlying the beneficial effect of beta-sitosterol on endothelial function...
  10. ncbi request reprint Evaluation of estrogenic/antiestrogenic activity of ellagic acid via the estrogen receptor subtypes ERalpha and ERbeta
    Zoi Papoutsi
    Department of Biological Chemistry, Medical School, University of Athens Mikras Asias Str 75, Goudi, Athens 11527, Greece
    J Agric Food Chem 53:7715-20. 2005
    ..Endometrium-derived epithelial cells (Ishikawa) showed no response to the natural compound by using a cell viability assay (MTT). These findings suggest that ellagic acid may be a natural selective estrogen receptor modulator (SERM)...
  11. doi request reprint Functional estrogen receptors alpha and beta are expressed in normal human salivary gland epithelium and apparently mediate immunomodulatory effects
    Maria Tsinti
    Department of Pathophysiology, National and Kapodistrian University of Athens, Athens, Greece
    Eur J Oral Sci 117:498-505. 2009
    ..This finding corroborated the functionality of ER expressed by SGEC. Our results suggest that salivary epithelium expresses constitutively functional ERalpha and ERbeta proteins that apparently mediate immunomodulatory effects...
  12. doi request reprint Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules
    John Lekakis
    2nd Department of Cardiology, Attikon Hospital, University of Athens, School of Medicine, Athens, Greece
    Int J Cardiol 139:150-8. 2010
    ....
  13. ncbi request reprint Plant 2-arylobenzofurans demonstrate a selective estrogen receptor modulator profile
    Zoi Papoutsi
    Laboratory of Biological Chemistry, Department of Biological Chemistry, Medical School, National University of Athens, 75 M Asias str, Goudi, GR 115 27 Athens, Greece
    Steroids 69:727-34. 2004
    ..In conclusion, our study is the first to demonstrate that plant derived arylobenzofurans show a SERM profile and may be considered for the prevention and treatment of diseases such as breast cancer, cervical cancer and osteoporosis...
  14. doi request reprint Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) alpha+beta+ transcript in estrogen receptor-positive MCF-7 breast cancer cells
    Areti Strati
    Laboratory of Analytical Chemistry, Department of Chemistry, University of Athens, Athens, 15771, Greece
    Clin Biochem 42:1358-62. 2009
    ..To evaluate the potential of ellagic acid to inhibit the expression of human telomerase reverse transcriptase (hTERT) alpha+beta+ splice variant in MCF-7 breast cancer cells...
  15. ncbi request reprint Effects of Sideritis euboea (Lamiaceae) aqueous extract on IL-6, OPG and RANKL secretion by osteoblasts
    Eva Kassi
    Department of Biological Chemistry, Medical School, University of Athens, 75 M Asias, Goudi, 11527 Athens, Greece
    Nat Prod Commun 6:1689-96. 2011
    ..An ESI source in negative mode was employed. The analysis indicated that the water extract of S. euboea is rich in flavonoid glycosides, and phenylpropanoid glycosides...
  16. doi request reprint Glucocorticoid receptor signaling in bone cells
    Paraskevi Moutsatsou
    Department of Biological Chemistry, University of Athens Medical School, 75, Mikras Asias Street, 11527 Athens, Greece
    Trends Mol Med 18:348-59. 2012
    ..We hope this knowledge will advance research in the development of SEGRAs with improved benefit/risk ratios...
  17. doi request reprint Chios mastic gum extract and isolated phytosterol tirucallol exhibit anti-inflammatory activity in human aortic endothelial cells
    Stella Loizou
    Department of Biological Chemistry, Medical School, University of Athens, and Second Department of Cardiology, University General Hospital, 75 Mikras Asias Str, Goudi, Athens, Attiki 11527, Greece
    Exp Biol Med (Maywood) 234:553-61. 2009
    ....
  18. ncbi request reprint Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties
    Eva Kassi
    Department of Biological Chemistry, Medical School, University of Athens, 115 27 Athens, Greece
    J Agric Food Chem 52:6956-61. 2004
    ..In conclusion, the aqueous extracts derived from Sideritis euboea, Sideritis clandestina, Marticaria chamomilla, and Pimpinella anisum may form the basis to design "functional foods" for the prevention of osteoporosis...
  19. ncbi request reprint Gene analysis of the glucocorticoid receptor alpha in Alzheimer's disease
    Amalia F Tsolakidou
    Department of Biological Chemistry, Medical School, University of Athens, 75 Mikras Asias Street, GR 115 27 Goudi, Athens, Greece
    Clin Chim Acta 349:167-72. 2004
    ....
  20. pmc Phenolic acid composition, antiatherogenic and anticancer potential of honeys derived from various regions in Greece
    Eliana Spilioti
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    PLoS ONE 9:e94860. 2014
    ....
  21. ncbi request reprint Application of denaturing gradient gel electrophoresis (DGGE) to screen for mutations of the human glucocorticoid receptor alpha gene (hGRalpha)
    Amalia F Tsolakidou
    Department of Biological Chemistry, Medical School, National University of Athens, 75 M Asias str, Goudi, 115 27 Athens, Greece
    Clin Biochem 36:305-11. 2003
    ..We now present an expanded screening methodology to detect mutations covering the whole length of hGRalpha...
  22. ncbi request reprint seco-Cycloartane triterpenes from Gardenia aubryi
    Raphael Grougnet
    Laboratory of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens GR 15771, Greece
    J Nat Prod 69:1711-4. 2006
    ..The in vitro cytotoxic activity of compounds 1-3 was evaluated against four human solid tumor cell lines...
  23. ncbi request reprint Lignans 7-hydroxymatairesinol and 7-hydroxymatairesinol 2 exhibit anti-inflammatory activity in human aortic endothelial cells
    Eliana Spilioti
    Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
    Mol Nutr Food Res 58:749-59. 2014
    ..7-Hydroxymatairesinol (HMR) and its major isomer 7-hydroxymatairesinol 2 (HMR2), lariciresinol, secoisolariciresinol, and pinoresinol, isolated from Norway spruce knots were examined...
  24. ncbi request reprint The dynamic localization of the glucocorticoid receptor in rat C6 glioma cell mitochondria
    Maria M Koufali
    Department of Psychiatry, Ninewells Hospital, University of Dundee Medical School, Dundee, DD1 9SY, UK
    Mol Cell Endocrinol 209:51-60. 2003
    ..The effects were inhibited by RU486. Therefore, GR is likely to have a functional role at the level of the mitochondria within intact cells...