Christos Markopoulos

Summary

Affiliation: Athens Medical School
Location: Athens, Greece
URL: www.markopoulos.gr

Publications

  1. ncbi Paraffinomas of the breast or oleogranulomatous mastitis-a rare entity
    C Markopoulos
    Breast Unit, 2nd Propaedeutic, Department of Surgery, Faculty of Medicine, University of Athens, Laiko General Hospital, 8, Iassiou Street, 11521 Athens, Greece
    Breast 15:540-3. 2006
  2. pmc Glycogen-rich clear cell carcinoma of the breast
    Christos Markopoulos
    Breast Unit, 2nd Propedeutic Department of Surgery, Athens University Medical School, Greece
    World J Surg Oncol 6:44. 2008
  3. ncbi Effect of exemestane on the lipidemic profile of post-menopausal operable breast cancer patients following 5-7 years of adjuvant tamoxifen: preliminary results of the ATENA substudy
    C Markopoulos
    Hellenic Breast Surgeons Society, Greece
    Anticancer Drugs 16:879-83. 2005
  4. pmc Evaluation of six CTLA-4 polymorphisms in high-risk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial
    Helen Gogas
    First Department of Medicine, University of Athens, Medical School, Athens, Greece
    J Transl Med 8:108. 2010
  5. pmc Managing bone health in women with breast cancer under adjuvant treatment with aromatase inhibitors: pretreatment bone mineral density is important
    Christos Markopoulos
    Breast Cancer Res 12:403. 2010
  6. pmc Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial
    Christos Markopoulos
    Hellenic Society of Breast Surgeons, 6 Eslin Street, Athens, Greece
    Breast Cancer Res 12:R24. 2010
  7. ncbi Fibroadenomas of the breast: is there any association with breast cancer?
    C Markopoulos
    Breast Unit 2nd Surgical Department, School of Medicine Laiko Hospital, Athens, Greece
    Eur J Gynaecol Oncol 25:495-7. 2004
  8. ncbi Breast arterial calcifications as an indicator of systemic vascular disease
    C Markopoulos
    Breast Unit, 2nd Department of Propedeutic Surgery, Athens University School of Medicine, Laiko General Hospital, Athens, Greece
    Acta Radiol 45:726-9. 2004
  9. ncbi Identification of germline BRCA1 and BRCA2 genetic alterations in Greek breast cancer moderate-risk and low-risk individuals--correlation with clinicopathological data
    A Kataki
    Laboratory of Surgical Research, Hippokarteion Hospital of Athens, Athens, Greece
    Clin Genet 67:322-9. 2005
  10. ncbi Paclitaxel and carboplatin as first-line chemotherapy combined with gefitinib (IRESSA) in patients with advanced breast cancer: a phase I/II study conducted by the Hellenic Cooperative Oncology Group
    George Fountzilas
    AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, Nea Efkarpia, 56249 Thessaloniki, Greece
    Breast Cancer Res Treat 92:1-9. 2005

Detail Information

Publications82

  1. ncbi Paraffinomas of the breast or oleogranulomatous mastitis-a rare entity
    C Markopoulos
    Breast Unit, 2nd Propaedeutic, Department of Surgery, Faculty of Medicine, University of Athens, Laiko General Hospital, 8, Iassiou Street, 11521 Athens, Greece
    Breast 15:540-3. 2006
    ..Complications due to paraffinoma reactions of breast tissue and skin, as well as progression of the disease and treatment of our patients, are presented here, together with a review of the relevant literature...
  2. pmc Glycogen-rich clear cell carcinoma of the breast
    Christos Markopoulos
    Breast Unit, 2nd Propedeutic Department of Surgery, Athens University Medical School, Greece
    World J Surg Oncol 6:44. 2008
    ..Glycogen-rich carcinoma of the breast is a rare histological subtype of breast cancer, usually reported to have poor prognosis...
  3. ncbi Effect of exemestane on the lipidemic profile of post-menopausal operable breast cancer patients following 5-7 years of adjuvant tamoxifen: preliminary results of the ATENA substudy
    C Markopoulos
    Hellenic Breast Surgeons Society, Greece
    Anticancer Drugs 16:879-83. 2005
    ....
  4. pmc Evaluation of six CTLA-4 polymorphisms in high-risk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial
    Helen Gogas
    First Department of Medicine, University of Athens, Medical School, Athens, Greece
    J Transl Med 8:108. 2010
    ..Specific CTLA-4 polymorphisms have previously shown an association with response to CTLA-4 blockade in patients with metastatic melanoma and the development of autoimmunity...
  5. pmc Managing bone health in women with breast cancer under adjuvant treatment with aromatase inhibitors: pretreatment bone mineral density is important
    Christos Markopoulos
    Breast Cancer Res 12:403. 2010
  6. pmc Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial
    Christos Markopoulos
    Hellenic Society of Breast Surgeons, 6 Eslin Street, Athens, Greece
    Breast Cancer Res 12:R24. 2010
    ....
  7. ncbi Fibroadenomas of the breast: is there any association with breast cancer?
    C Markopoulos
    Breast Unit 2nd Surgical Department, School of Medicine Laiko Hospital, Athens, Greece
    Eur J Gynaecol Oncol 25:495-7. 2004
    ..The experience of our Breast Unit in the diagnosis and treatment of fibroadenomas is presented in this retrospective study, focusing specifically in cancer development within these common benign tumors of young age...
  8. ncbi Breast arterial calcifications as an indicator of systemic vascular disease
    C Markopoulos
    Breast Unit, 2nd Department of Propedeutic Surgery, Athens University School of Medicine, Laiko General Hospital, Athens, Greece
    Acta Radiol 45:726-9. 2004
    ..To evaluate the association between mammographically detected arterial calcifications and systemic vascular disease...
  9. ncbi Identification of germline BRCA1 and BRCA2 genetic alterations in Greek breast cancer moderate-risk and low-risk individuals--correlation with clinicopathological data
    A Kataki
    Laboratory of Surgical Research, Hippokarteion Hospital of Athens, Athens, Greece
    Clin Genet 67:322-9. 2005
    ..Breast cancer due to mutations in BRCA1 and BRCA2 genes appears to be a heterogeneous syndrome in the Greek population...
  10. ncbi Paclitaxel and carboplatin as first-line chemotherapy combined with gefitinib (IRESSA) in patients with advanced breast cancer: a phase I/II study conducted by the Hellenic Cooperative Oncology Group
    George Fountzilas
    AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, Nea Efkarpia, 56249 Thessaloniki, Greece
    Breast Cancer Res Treat 92:1-9. 2005
    ..7 and 42.7%, respectively), with the majority (72.1%) negative for cytoplasmic p27(kipl). The observed efficacy data in this study were similar to those reported for the combination of paclitaxel and carboplatin alone...
  11. pmc Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: a prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial
    John M S Bartlett
    Endocrine Cancer Group, Edinburgh Cancer Research Centre, Western General Hospital, Crewe Rd South, Edinburgh, EH4 2XR, United Kingdom
    J Clin Oncol 29:1531-8. 2011
    ....
  12. ncbi Adiponectin and breast cancer risk
    Christos Mantzoros
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Clin Endocrinol Metab 89:1102-7. 2004
    ..Future studies are needed to prove causality and provide further insights into both the mechanisms underlying the actions of this hormone and its potential role in breast cancer...
  13. ncbi Pre-operative Tc-99m-sestamibi scanning and intra-operative nuclear mapping: are they accurate in localizing parathyroid adenomas?
    J Gogas
    2nd Department of Propedeutic Surgery, 1st Department of Internal Medicine, Departments of Nuclear Medicine and Pathology, Athens University Medical School Laiko General Hospital, 17 Ag Thomas Str 115 27 Athens, Greece
    Acta Chir Belg 103:626-30. 2003
    ..Presentation of the results of Tc-99m-sestamibi imaging in the pre-operative localization of parathyroid adenomas and the intra-operative localization of those lesions using a gamma detector (prospective study)...
  14. ncbi Docetaxel and epirubicin supported by granulocyte colony-stimulating factor first-line in advanced breast cancer
    Aristides Polyzos
    Medical Oncology Unit, Laikon General Hospital, Athens University School of Medicine, 17 Agiou Thoma Street, Goudi, GR 11527, Athens, Greece
    Anticancer Res 23:2917-23. 2003
    ..Although myelosuppression remains the major toxicity, prophylactic GCSF administration was associated with a small percentage of neutropenic fever...
  15. ncbi Adenosis tumor of the breast
    C Markopoulos
    Breast J 9:255-6. 2003
  16. ncbi Mucosa-associated lymphoid tissue thyroid lymphoma: a rare and not aggressive tumour
    John Gogas
    Second Department of Propedeutic Surgery, Athens University Medical School, Laikoe General Hospital of Athens, Athens, Greece
    Eur J Surg 168:572-4. 2002
  17. ncbi Metastatic melanoma in the gallbladder: report of a case
    John Gogas
    Second Department of Propedeutic Surgery, Athens University School of Medicine, Laiko General Hospital, Ag Thomas Str 17, 115 27 Goudi, Athens, Greece
    Surg Today 33:135-7. 2003
    ..Surgical removal of a solitary metastatic focus remains the treatment of choice for isolated metastasis of a malignant melanoma; however, the effectiveness of complementary chemotherapy and immunotherapy is still being examined...
  18. ncbi Neoadjuvant chemotherapy with a combination of pegylated liposomal doxorubicin (Caelyx) and paclitaxel in locally advanced breast cancer: a phase II study by the Hellenic Cooperative Oncology Group
    H Gogas
    First Department of Medicine, Laiko Hospital, University of Athens, Greece
    Ann Oncol 13:1737-42. 2002
    ..To determine the activity and safety of the combination of paclitaxel and pegylated liposomal doxorubicin (Caelyx) in patients with locally advanced breast cancer...
  19. ncbi Postoperative dose-dense sequential chemotherapy with epirubicin, followed by CMF with or without paclitaxel, in patients with high-risk operable breast cancer: a randomized phase III study conducted by the Hellenic Cooperative Oncology Group
    G Fountzilas
    Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece
    Ann Oncol 16:1762-71. 2005
    ....
  20. ncbi The effect of exemestane on the lipidemic profile of postmenopausal early breast cancer patients: preliminary results of the TEAM Greek sub-study
    C Markopoulos
    Hellenic Breast Surgeons Society HBSS, 8 Iassiou Street, Athens, Attica 11521, Greece
    Breast Cancer Res Treat 93:61-6. 2005
    ....
  21. ncbi Development of early malignant bilateral breast disease in relation to antidepressant treatment
    C Markopoulos
    Breast Unit 2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Athens, Greece
    Acta Chir Belg 105:660-1. 2005
    ..The role of that type of agents in the breast pathology is briefly discussed, based on the data of the current literature...
  22. doi Phantom breast syndrome: The effect of in situ breast carcinoma
    Christos J Markopoulos
    Second Department of Propedeutic Surgery, University of Athens, Athens, Greece
    Psychiatry Res 179:333-7. 2010
    ..The absence of infiltration in primary tumour histology, probably through an unknown pathophysiological mechanism, might play a role for the significantly higher incidence of PBS in women undergoing mastectomy for DCIS...
  23. ncbi Impact of breast cancer surgery on the self-esteem and sexual life of female patients
    C Markopoulos
    Breast Unit, Second Department of Surgery, Athens University Medical School Laiko General Hospital, Athens, Greece
    J Int Med Res 37:182-8. 2009
    ..Diagnosis of breast cancer has a negative psychological impact on the patient, but the type of surgery has a significant role in post-operative self-esteem and sexual life...
  24. doi Lipid changes in breast cancer patients on exemestane treatment: final results of the TEAM Greek substudy
    C Markopoulos
    Department of Breast Surgery, Medical School, University of Athens, Athens, Greece
    Ann Oncol 20:49-55. 2009
    ..The Greek substudy of the Tamoxifen and Exemestane Adjuvant Multicenter International trial compared the effect of exemestane on the lipid profile of postmenopausal, breast cancer patients to that of tamoxifen in the adjuvant setting...
  25. ncbi DNA ploidy and pS2 protein expression in breast cancer
    A Ioakim-Liossi
    Department of Clinical Cytology and Cytogenetics, Medical School, Athens University, Greece
    Cytopathology 8:171-6. 1997
    ..01). The percentage of aneuploid tumours increased from pS2+ to pS2- breast tumours (P < 0.001). These findings may be indicative of pS2 and DNA ploidy alterations and tumour aggressiveness...
  26. doi Safely promoting breast-conserving surgery and preventing early relapses with an aromatase inhibitor
    Christos Markopoulos
    Athens Medical School, University of Athens, GR 11521 Athens, Greece
    Surg Oncol 17:113-28. 2008
    ..Early and long-term-risk reduction with AI treatment should be discussed with patients, as should the management of common AI-associated adverse events...
  27. ncbi Postoperative dose-dense sequential chemotherapy with epirubicin, paclitaxel and CMF in patients with high-risk breast cancer: safety analysis of the Hellenic Cooperative Oncology Group randomized phase III trial HE 10/00
    G Fountzilas
    Department of Medical Oncology, Papageorgiou Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Ann Oncol 19:853-60. 2008
    ..A randomized phase III trial in high-risk breast cancer patients was conducted, to further explore the impact of dose-density in the adjuvant treatment for breast cancer. The safety analysis is presented...
  28. ncbi Depressive symptomatology correlates with phantom breast syndrome in mastectomized women
    Areti C Spyropoulou
    Department of Psychiatry, Eginition Hospital, University of Athens, Athens, Greece
    Eur Arch Psychiatry Clin Neurosci 258:165-70. 2008
    ..This study aimed to assess possible correlations of PBS to current psychopathology and personality dimensions, as well as to examine subjectively experienced provoking and relieving factors for the experience of PBS...
  29. ncbi Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients
    Irene Konstantopoulou
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Breast Cancer Res Treat 107:431-41. 2008
    ..The suggested protocol can impact on the clinical management of breast-ovarian cancer families on a national healthcare system level...
  30. ncbi Duration of tamoxifen effect on lipidemic profile of postmenopausal breast cancer patients following deprivation of treatment
    C Markopoulos
    Hellenic Breast Surgeons Society, Athens, Greece
    Oncology 70:301-5. 2006
    ..It was the aim of this study to investigate the effect of tamoxifen withdrawal on markers of lipid metabolism in postmenopausal women with breast cancer who completed tamoxifen therapy and received no further treatment...
  31. ncbi Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group
    H Gogas
    First Department of Medicine, University of Athens, Medical School, Athens, Greece
    Ann Oncol 17:1835-41. 2006
    ..We designed a phase II study to assess the efficacy and toxicity of the combination of TMZ and celecoxib (a COX-2 inhibitor) in patients with advanced melanoma...
  32. ncbi Evaluation of the prognostic value of HER-2 and VEGF in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy
    Ioannis Kostopoulos
    Aristotle University of Thessaloniki, School of Medicine, Thessaloniki, Greece
    Breast Cancer Res Treat 96:251-61. 2006
    ..To assess the prognostic and predictive significance of HER-2 overexpression and high expression of VEGF in high-risk patients with breast cancer treated with dose-dense sequential chemotherapy...
  33. ncbi Prognostic significance of autoimmunity during treatment of melanoma with interferon
    Helen Gogas
    First Department of Medicine, Laiko Hospital, Athens, Greece
    N Engl J Med 354:709-18. 2006
    ..We assessed the prognostic significance of autoimmunity in patients with stage IIB, IIC, or III melanoma who were treated with high-dose adjuvant interferon alfa-2b...
  34. ncbi Granular cell tumor of the breast: a rare lesion resembling breast cancer
    J Gogas
    2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Greece
    Eur J Gynaecol Oncol 23:333-4. 2002
    ..Computer tomography (CT) showed a 3.74 cm mass in the mammary tail of Spencer. The findings were suspicious for malignancy and the lesion was widely resected. Pathologic examination showed granular cell tumor...
  35. ncbi Paget's disease of the nipple occurring after conservative management of early breast cancer
    C Markopoulos
    Combined Breast Clinic, St George s Hospital, Tooting, London, UK
    Eur J Surg Oncol 14:77-8. 1988
    ....
  36. ncbi Bilateral Paget's disease of the breast
    C Markopoulos
    B Propedeutic Department of Surgery, Medical School, University of Athens, Greece
    Eur J Gynaecol Oncol 18:495-6. 1997
    ..A rare case of metachronous bilateral Paget's disease of the nipple is presented. The occasional failure of routine follow-up to detect certain tumours until biologically advanced and the value of patient observations are mentioned...
  37. ncbi 99mTc Tetrofosmin imaging in breast tumours
    C Markopoulos
    B Propedeutic Department of Surgery, Medical School University of Athens, Greece
    Eur J Gynaecol Oncol 19:163-6. 1998
    ..The sensitivity of the method was 90.32% and the specificity 91.30%, with a positive predictive value of 96.55%. We conclude that breast scanning with 99mTc Tetrofosmin may play an important role in the detection of breast malignancies...
  38. ncbi Cavernous haemangioma of the breast. A case report
    C Markopoulos
    B Propedeutic Department of Surgery, Medical School, University of Athens, Greece
    Eur J Gynaecol Oncol 19:246-8. 1998
  39. ncbi Mucoepidermoid carcinoma of the breast
    C Markopoulos
    B Propedeutic Department of Surgery, Medical School, University of Athens, Greece
    Eur J Gynaecol Oncol 19:291-3. 1998
    ..This report describes a case of high-grade mucoepidermoid carcinoma of the breast with a disease-free interval of 5 years, despite of unfavourable histologic features at the time of diagnosis...
  40. ncbi The prognostic value of alpha-thymosins in breast cancer
    O E Tsitsilonis
    Cancer Immunology and Immunotherapy Centre, St Savas Cancer Hospital, Athens, Greece
    Anticancer Res 18:1501-8. 1998
    ..The fact that such relationships hold only for cancer tissues encourages the future use of alpha-thymosins as potent prognostic factors in breast cancer...
  41. ncbi p53 protein expression in benign and malignant breast lesions
    A Ioakim-Liossi
    Department of Pathology, Medical School, University of Athens, Greece
    Acta Cytol 42:918-22. 1998
    ..To investigate p53 protein expression in imprints from benign and ductal breast carcinoma cases in relation to the histologic grade of malignancy and clinical stage...
  42. ncbi Association of breast cancer with meningioma
    C Markopoulos
    2nd Propedeutic Department of Surgery, Medical School, University of Athens, Greece
    Eur J Surg Oncol 24:332-4. 1998
    ..The knowledge of this association is important in the differential diagnosis of patients with breast cancer who develop central nervous system manifestations...
  43. pmc Alterations of p16-pRb pathway and chromosome locus 9p21-22 in sporadic invasive breast carcinomas
    V G Gorgoulis
    Department of Histology and Embryology, School of Medicine, University of Athens, Greece
    Mol Med 4:807-22. 1998
    ....
  44. ncbi DNA content and p53 protein expression in ductal breast cancer
    A Ioakim-Liossi
    Department of Pathology, Medical School, University of Athens, Greece
    Cytopathology 8:322-7. 1997
    ..Clonal DNA heterogeneity was observed in 26.6% of cases analysed and was correlated with p53 protein expression (P < 0.001). These changes probably reflect genomic alterations which may affect potential malignancy of breast cancer...
  45. ncbi Expression of pS2 protein and estrogen and progesterone receptor status in breast cancer
    A Ioakim-Liossi
    Department of Clinical Cytology and Cytogenetics, University of Athens Medical School, Greece
    Acta Cytol 41:713-6. 1997
    ..To investigate pS2 protein expression and estrogen (ER) and progesterone receptor (PR) status of imprints from surgical biopsies of breast cancer cases in relation to the histologic grade of malignancy...
  46. ncbi Prospective randomised trial of tamoxifen versus surgery in elderly patients with breast cancer
    J C Gazet
    Breast Unit, St George s Hospital, London
    Lancet 1:679-81. 1988
    ..There were 13 deaths in the tamoxifen group and 11 in the surgical arm, of which 8 and 9, respectively, were attributable to breast cancer. Disease-free survival did not differ between the groups...
  47. ncbi Tamoxifen and breast cancer in the elderly
    J C Gazet
    Lancet 1:1218. 1988
  48. pmc Oestrogen receptor content of normal breast cells and breast carcinomas throughout the menstrual cycle
    C Markopoulos
    St George s Hospital, London
    Br Med J (Clin Res Ed) 296:1349-51. 1988
    ..In contrast, breast carcinoma cells either synthesise this protein continuously throughout the cycle or fail to express it despite fluctuations of serum hormone concentrations...
  49. ncbi Obstructive colonic cancer
    A Papachristodoulou
    2nd Propedeutic Surgical Department, Athens University School of Medicine, Greece
    J R Coll Surg Edinb 38:296-8. 1993
    ..The high incidence of advanced disease, advanced age, delay in tumour excision and unprepared bowel are some of the factors resulting in the poor prognosis of these patients...
  50. ncbi Bilateral breast cancer
    J Gogas
    Second Propedeutic Department of Surgery, University of Athens, Greece
    Am Surg 59:733-5. 1993
    ..4 per cent. Our results indicate that the risk of developing, a contralateral breast cancer is related to the patient's age, family history of breast cancer, and lobular histology of the tumor...
  51. ncbi DNA ploidy and vimentin expression in primary breast cancer
    A Ioakim-Liossi
    Department of Clinical Cytology and Cytogenetics, Athens University, Greece
    Cytopathology 6:325-30. 1995
    ..05) Clonal heterogeneity was observed in 25% of breast carcinomas, and was associated with increased vimentin expression. These changes may be indicative of genomic alteration and tumour aggressiveness...
  52. ncbi Endometrioid carcinoma arising in a scar of caesarean section. Case report
    C Markopoulos
    2nd Department of Surgery, Medical School, Athens University, Greece
    Eur J Gynaecol Oncol 17:520-1. 1996
    ..Development of malignancy in such a lesion is very unusual. A rare case of primary endometrioid carcinoma in the endometriosis of a caesarean scar is described...
  53. ncbi Medullary carcinoma of the thyroid gland
    J Gogas
    Am Surg 53:347-9. 1987
    ..The best chance of cure lies in early diagnosis and an aggressive surgical removal of the primary tumor and any cervical metastases...
  54. ncbi Changes of chromosomes 1, 3, 6, and 11 in metastatic effusions arising from breast and ovarian cancer
    A Ioakim-Liossi
    Department of Pathology, Athens School of Medicine, University of Athens, Greece
    Cancer Genet Cytogenet 110:34-40. 1999
    ..This study provides further cytogenetic evidence for the involvement of these chromosomes in breast and ovarian malignancy...
  55. ncbi Factors affecting axillary lymph node metastases in patients with T1 breast carcinoma
    C Markopoulos
    2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Greece
    Am Surg 66:1011-3. 2000
    ..g., elderly patients with clinically negative axilla). Axillary dissection (at least levels I and II) should be performed in all cases with primary invasive breast cancer with tumor size > 5 mm...
  56. ncbi Autoimmune thyroid disease in women with breast carcinoma
    J Gogas
    Breast Unit, 2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, 17 Ag. Thomas Street, 115 27 Athens, Greece
    Eur J Surg Oncol 27:626-30. 2001
    ..4% autoantibody positivity). CONCLUSIONS: There is evidence of high incidence of autoimmune thyroiditis in Greek breast cancer patients, increasing in relation to cancer stage...
  57. ncbi Alterations of the 16q22.1 and 16q24.3 chromosomal loci in sporadic invasive breast carcinomas: correlation with proliferative activity, ploidy and hormonal status of the tumors
    M Kouvaraki
    Laboratory of Histology and Embryology, University of Athens School of Medicine, Athens, Greece
    Anticancer Res 21:991-9. 2001
    ..The statistical association between LOH of 16q24.3 and progesterone receptors need to be further investigated in larger series...
  58. ncbi Primary actinomycosis of the greater omentum
    A J Papachristodoulou
    J Infect 43:159-60. 2001
  59. ncbi Leptin and insulin growth factor I in relation to breast cancer (Greece)
    E Petridou
    Department of Hygiene and Epidemiology, Athens University Medical School, Greece
    Cancer Causes Control 11:383-8. 2000
    ..We have also evaluated in this dataset the association of IGF-I with breast cancer...
  60. ncbi Senology: the urgent need for establishing rules for expert training and organization of multidisciplinary breast units
    C J Markopoulos
    2nd Propeduetic Department of Surgery, Athens University Medical School and Laiko General Hospital, Greece
    Eur J Gynaecol Oncol 20:53-5. 1999
  61. ncbi Carcinosarcoma of the submandibular salivary gland
    J Gogas
    2nd Propedeutic Department of Surgery, Athens University and Medical School, Laikon Hospital, Greece
    Eur J Surg Oncol 25:333-5. 1999
    ..A short review of the literature is also presented and the poor prognosis of these tumours, in spite of complete surgical removal and additional radiation therapy and chemotherapy, is discussed...
  62. ncbi Local recurrence after radical surgery for colorectal cancer
    A Papachristodoulou
    Second Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Greece
    Int Surg 87:19-24. 2002
    ..The only hope for long-term survival for patients presenting with local recurrence from colorectal cancer after primary radical treatment is to identify local recurrence at an early stage and treat it in a radical manner...
  63. ncbi Radial scar of the breast
    C Markopoulos
    2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Greece
    Eur J Gynaecol Oncol 20:147-9. 1999
    ..The surgeon, the radiologist and the pathologist should be aware of this clinical entity which, in spite of its benign character, has the ability to simulate invasive carcinoma clinically, mammographically and histopathologically...
  64. ncbi Evaluation of cytological morphologic criteria and AgNOR expression in male breast lesions
    P Karakitsos
    Department of Clinical Cytology and Cytogenetics, Laiko Hospital, Athens, Greece
    Cytopathology 9:107-13. 1998
    ..Our experience suggests that FNA is an acceptable procedure for the investigation of male breast lesions...
  65. pmc Age effect on bone mineral density changes in breast cancer patients receiving anastrozole: results from the ARBI prospective clinical trial
    Christos Markopoulos
    Hellenic Society of Breast Surgeons, 6 Eslin Street, 11523, Athens, Greece
    J Cancer Res Clin Oncol 138:1569-77. 2012
    ..We conducted a post hoc analysis of the dataset of Arimidex Bone Mass Index Oral Bisphosphonates prospective trial, studying the effect of risedronate (R) on BMD of postmenopausal, early breast cancer patients receiving A...
  66. pmc Minimizing early relapse and maximizing treatment outcomes in hormone-sensitive postmenopausal breast cancer: efficacy review of AI trials
    Christos J Markopoulos
    Athens University Medical School, 8, Iassiou str, 11521 Athens, Greece
    Cancer Metastasis Rev 29:581-94. 2010
    ....
  67. pmc Extended adjuvant hormonal therapy with exemestane has no detrimental effect on the lipid profile of postmenopausal breast cancer patients: final results of the ATENA lipid substudy
    Christos Markopoulos
    Hellenic Society of Breast Surgeons, Athens, Greece
    Breast Cancer Res 11:R35. 2009
    ....
  68. ncbi Full dose paclitaxel plus vinorelbine as salvage chemotherapy in anthracycline-resistant advanced breast cancer: a phase II study
    A Polyzos
    Medical Oncology Unit, Laikon General Hospital, Athens University School of Medicine, 17 Agiou Thoma Street, Goudi, Athens, Greece
    J Chemother 15:607-12. 2003
    ..The combination at these doses and schedules should be considered in the design of regimens for advanced breast cancer...
  69. ncbi Should women be advised to take prophylactic endocrine treatment outside of a clinical trial setting?
    H Gogas
    First Department of Internal Medicine, Athens Medical School, National and Kapodistrian University of Athens, Athens, Greece
    Ann Oncol 16:1861-6. 2005
    ..High-risk women should not be advised to take anti-estrogens outside of a clinical trial setting...
  70. ncbi Open surgical biopsy for nonpalpable breast lesions detected on screening mammography
    C Markopoulos
    Breast Unit, 2nd Department of Propedeutic Surgery, Athens Medical School, Laiko General Hospital, Greece
    Eur J Gynaecol Oncol 26:311-4. 2005
    ..Frozen section is feasible and accurate in the majority of these lesions, and therefore, diagnostic and therapeutic one-step surgical procedures could be performed...
  71. ncbi Mitoxantrone plus vinorelbine in pretreated patients with metastatic breast cancer
    A Onyenadum
    Hellenic Cooperative Oncology Group, Data Office, Athens, Greece
    J Chemother 19:582-9. 2007
    ..Febrile neutropenia was recorded in one patient. There were no treatment related deaths. The combination of mitoxantrone and vinorelbine is an effective regimen with manageable toxicity in pretreated patients with advanced breast cancer...
  72. ncbi Carcinosarcoma of the breast: report of two cases
    J Gogas
    2 Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Athens, Greece
    Eur J Gynaecol Oncol 24:93-5. 2003
    ..This tumor should be distinguished from other forms of metaplastic carcinomas because it is very aggressive and has an ominous prognosis...
  73. ncbi Surgical management of nipple discharge
    C Markopoulos
    Breast Unit, 2nd Department of Propedeutic Surgery, Athens University School of Medicine, Laiko General Hospital, Athens, Greece
    Eur J Gynaecol Oncol 27:275-8. 2006
    ..Nipple discharge is reported in 2.5-3% of women with breast carcinoma. Breast carcinoma is found in approximately 8% of surgically treated patients presenting with bloody nipple discharge (ND)...
  74. ncbi Use of artificial neural networks (computer analysis) in the diagnosis of microcalcifications on mammography
    C Markopoulos
    Breast Unit, Second Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital of Athens, 8 Iassiou street 115218, Athens, Greece
    Eur J Radiol 39:60-5. 2001
    ....
  75. ncbi Computer-aided preoperative diagnosis of microcalcifications on mammograms
    E Kouskos
    Breast Unit, 2nd Department of Propedeutic Surgery, University Medical School, Laiko General Hospital of Athens, Greece
    Acta Radiol 44:43-6. 2003
    ..To evaluate of a computer-aided method for differentiating malignant from benign clustered microcalcifications...
  76. ncbi Missed cancers on mammograms: causes and measures of prevention
    E Kouskos
    Breast Unit, 2nd Department of Propedeutic Surgery, Medical School Laiko General Hospital of Athens, Greece
    Eur J Gynaecol Oncol 25:230-2. 2004
    ....
  77. ncbi Breast cancer risk in relation to most prevalent IgE specific antibodies: a case control study in Greece
    E T Petridou
    Unit of Preventive Medicine, Department of Hygiene and Epidemiology and School of Medicine, University of Athens, Athens 11527, Greece
    Anticancer Res 27:1709-13. 2007
    ..This study aims to explore the debatable role of allergy in breast cancer (BC) by using country-specific biological markers, namely levels of the most prevalent allergen-specific immunoglobulin E in Greece...
  78. ncbi Mondor's disease of the breast: is there any relation to breast cancer?
    C Markopoulos
    Breast Unit 2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Athens, Greece
    Eur J Gynaecol Oncol 26:213-4. 2005
    ..Only one of our patients had surgical management (vein excision) due to delayed remission. None of our cases was related to breast cancer...
  79. ncbi Breast cancer in ectopic breast tissue
    C Markopoulos
    2nd Department of Propedeutic Surgery, Athens University Medical School and Laiko Hospital, Greece
    Eur J Gynaecol Oncol 22:157-9. 2001
    ..They were all successfully treated by surgery and adjuvant therapy. A review of the literature on the incidence and pathology of ectopic mammary tissue is also presented...
  80. ncbi High expression levels of p27 correlate with lymph node status in a subset of advanced invasive breast carcinomas: relation to E-cadherin alterations, proliferative activity, and ploidy of the tumors
    Maria Kouvaraki
    Laboratory of Histology and Embryology, University of Athens School of Medicine, Athens, Greece
    Cancer 94:2454-65. 2002
    ..Although its levels are inversely associated with tumor proliferation, overexpression of p27 has been reported in a subset of rapidly proliferating breast carcinoma cell lines...
  81. ncbi Diagnosis and treatment of intracystic breast carcinomas
    Christos Markopoulos
    Second Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Greece
    Am Surg 68:783-6. 2002
    ..Bloodstained aspirated cyst fluid should be sent for cytology and breast imaging should be carried out in all these cases. Residual mass after cyst aspiration is also an indication for open biopsy...
  82. ncbi Immunohistochemical evaluation of immune response in invasive ductal breast cancer of not-otherwise-specified type
    Stephanie Vgenopoulou
    Department of Pathology, School of Medicine, The Athens National and Kapodistrian University, 75 Mikras Asias Str, Goudi, GR 115 27, Athens, Greece
    Breast 12:172-8. 2003
    ..In conclusion, tumors with markers of poor prognosis exhibited increased numbers of lymphocytic infiltrates, and of NK cells in particular, and stronger MUC1 and MUC6 glycoprotein immunoreactivity than did the other tumors...