Research Topics
Species | M MarkianosSummaryAffiliation: University of Athens Country: Greece Publications
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Publications
Platelet monoamine oxidase activity and psychometric correlates in male violent offenders imprisoned for homicide or other violent actsMarkos Skondras
Athens University Medical School, Eginition Hospital, Psychiatric Dept, Laboratory of Clinical Neurochemistry, Athens, Greece
Eur Arch Psychiatry Clin Neurosci 254:380-6. 2004..01) in the offenders' group (38.1+/-14.4) compared to controls (44.7+/-15.2). The difference could not be attributed to smoking, and seems to be related to personality traits and behaviors that characterize the offenders' group...
Evidence for involvement of central noradrenergic activity in crying pronenessManolis Markianos
Dept of Neurology, Athens University Medical School, Eginition Hospital, Athens, Greece
J Neuropsychiatry Clin Neurosci 23:403-8. 2011..It is suggested that central noradrenergic mechanisms control the threshold for tear production in normal crying behavior...- Platelet monoamine oxidase activity in subjects tested for Huntington's disease gene mutationM Markianos
Athens University Medical School, Eginition Hospital, Neurologic Clinic, Athens, Greece
J Neural Transm 111:475-83. 2004.... - Plasma testosterone in male patients with Huntington's disease: relations to severity of illness and dementiaManolis Markianos
Department of Neurology, Athens University Medical School, Eginition Hospital, Athens, Greece
Ann Neurol 57:520-5. 2005.... - Reductions in plasma prolactin during acute erythropoietin administrationManolis Markianos
Athens University Medical School, Eginition Hospital, Department of Neurology, Vas Sophias 74, Athens 11528, Greece
Neuro Endocrinol Lett 27:355-8. 2006..Preclinical data suggest that it may slow down the process of neuronal loss, and that EPO may cause dopamine release, and thus influence hormone release, especially prolactin. This possibility has not yet been studied in humans... - Plasma testosterone and dehydroepiandrosterone sulfate in male and female patients with dysthymic disorderManolis Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Vas Sophias 74, Athens 11528, Greece
J Affect Disord 101:255-8. 2007..Regarding dysthymic disorder (DD), low serum testosterone levels have been reported in older males, while information on younger male or on female patients is lacking... - Plasma testosterone, dehydroepiandrosterone sulfate, and cortisol in female patients with Huntington's diseaseManolis Markianos
Department of Neurology, Eginition Hospital, Athens University Medical School, Athens, Greece
Neuro Endocrinol Lett 28:199-203. 2007..While in male HD patients low plasma testosterone levels have been reported, information on female patients is lacking... - Low plasma total cholesterol in patients with Huntington's disease and first-degree relativesManolis Markianos
Athens University Medical School, Department of Neurology, Eginition Hospital, Vas Sophias 74, Athens 11528, Greece
Mol Genet Metab 93:341-6. 2008.... - Plasma homovanillic acid and prolactin in Huntington's diseaseManolis Markianos
Department of Neurology, Eginition Hospital, Athens University Medical School, Athens, Greece
Neurochem Res 34:917-22. 2009..Plasma HVA levels may be proven to be a peripheral index of disease progression. Reducing dopaminergic activity may have not only symptomatic, but also neuroprotective effects in HD... - Relationship of CSF neurotransmitter metabolite levels to disease severity and disability in multiple sclerosisManolis Markianos
Department of Neurology, Athens University Medical School, Eginition Hospital, Athens, Greece
J Neurochem 108:158-64. 2009.... - CSF neurotransmitter metabolites and neuropsychiatric symptomatology in patients with normal pressure hydrocephalusManolis Markianos
Athens University Medical School, Eginition Hospital, Department of Neurology, Vas Sophias 74, Athens 11528, Greece
Clin Neurol Neurosurg 111:231-4. 2009..Serotonergic neurotransmitter activity seems not to be altered in NPH patients, and this may explain the reported lack of beneficial effect of serotonergic drugs for obsessive-compulsive symptoms in NPH patients... - Suicide attempt by jumping: a study of gonadal axis hormones in male suicide attempters versus men who fell by accidentManolis Markianos
Laboratory of Clinical Neurochemistry, Eginition Hospital, Athens University Medical School, Vas Sophias 74, Athens, 11528, Greece
Psychiatry Res 170:82-5. 2009..Monitoring HPG axis function in future studies could prove to be a predictor of suicide at least for male psychiatric attempters, and could lead to preventive strategies... - Serum total cholesterol correlates positively to central serotonergic turnover in male but not in female subjectsManolis Markianos
Athens University Medical School, Eginition Hospital, Department of Neurology, Greece
Prog Neuropsychopharmacol Biol Psychiatry 34:527-31. 2010.... - Serum and cerebrospinal fluid prolactin levels in male and female patients with clinically-isolated syndrome or relapsing-remitting multiple sclerosisM Markianos
Department of Neurology, Athens University Medical School, Eginition Hospital, Athens, Greece
J Neuroendocrinol 22:503-8. 2010.... - Neuroendocrine evidence of normal hypothalamus-pituitary dopaminergic function in Huntington's diseaseManolis Markianos
Athens University Medical School, Department of Neurology, Eginition Hospital, Athens, Greece
Neuro Endocrinol Lett 31:359-62. 2010..OBJECTIVEs: In addition to neuronal loss in striatum and cerebral cortex that characterizes Huntington's disease (HD), hypothalamic atrophy has also been found only in certain areas, probably not including dopaminergic functions... - Serotonergic and dopaminergic neuroendocrine responses of male depressive patients before and after a therapeutic ECT courseManolis Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Vas Sophias 74, Athens 11528, Greece
Eur Arch Psychiatry Clin Neurosci 252:172-6. 2002.... - Relationship between prolactin responses to ECT and dopaminergic and serotonergic responsivity in depressed patientsManolis Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Vas Sophias 74, Athens 11528, Greece
Eur Arch Psychiatry Clin Neurosci 252:166-71. 2002.... - Switch from neuroleptics to clozapine does not influence pituitary-gonadal axis hormone levels in male schizophrenic patientsM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Greece
Eur Neuropsychopharmacol 9:533-6. 1999..The results show that switching from classical neuroleptics to treatment with clozapine does not have any substantial effect on the HPG-axis hormone plasma levels, although it reduces substantially the levels of prolactin and cortisol... - Dopamine receptor responsivity in schizophrenic patients before and after switch from haloperidol to risperidoneM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Greece
Psychiatry Res 89:115-22. 1999..7 ng/ml plasma (S.D. = 19.6). This high potency of risperidone to increase PRL levels cannot be explained by the serotonergic blocking activity of the drug, and seems not to be restricted to its D2 receptor blocking capacity... - Dopamine receptor responsivity in alcoholic patients before and after detoxificationM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Greece
Drug Alcohol Depend 57:261-5. 2000..To assess central dopamine receptor responsivity in alcoholic patients during their usual alcohol consumption and after detoxification... - Neuroendocrine serotonergic and dopaminergic responsivity in male schizophrenic patients during treatment with neuroleptics and after switch to risperidoneM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Vass Sophias 74, 11528 Athens, Greece
Psychopharmacology (Berl) 157:55-9. 2001.... - Changes in dopamine receptor responsivity during alcohol detoxification may predict relapseM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Vas Sophias 74, Athens, Greece
Drug Alcohol Depend 64:363-5. 2001.... - Neuroendocrine responsivities of the pituitary dopamine system in male schizophrenic patients during treatment with clozapine, olanzapine, risperidone, sulpiride, or haloperidolM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital Vass Sophias 74 Athens 11528, Greece
Eur Arch Psychiatry Clin Neurosci 251:141-6. 2001..m. administered haloperidol, since the expected elevations depend mainly on the free remaining D2 receptors in the tuberoinfundibular tract... - Prolactin responses to acute clomipramine and haloperidol of male schizophrenic patients in a drug-free state and after treatment with clozapine or with olanzapineM Markianos
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Vas Sophias 74, 11528 Athens, Greece
Schizophr Res 56:11-7. 2002.... - Provocation of neurocardiogenic syncope by clomipramine administration during the head-up tilt test in vasovagal syndromeG N Theodorakis
Onassis Cardiac Surgery Center, Second Department of Cardiology, Athens, Greece
J Am Coll Cardiol 36:174-8. 2000..We sought to test the hypothesis that activation of the serotonergic system in patients with vasovagal syndrome during the head-up tilt test provokes syncope... - Dopamine receptor responsivity in schizophrenic patients in a drug-free state and after treatment with olanzapineL Lykouras
Athens University Medical School Department of Psychiatry, Eginition Hospital, Greece
Prog Neuropsychopharmacol Biol Psychiatry 25:507-18. 2001..27, p=0.000008). Namely, in the drug-free state significant increases were found in the PRL levels after i.m. HAL administration which were significantly reduced during treatment with OLZ, indicating moderate receptor blockade... - Prolactin and cortisol responses to acute intravenous clomipramine challenge in patients with mania, depression and healthy controls: evidence for reduced serotonergic responsivityL Lykouras
Second Department of Psychiatry, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
Neuropsychobiology 63:77-81. 2011..The blunted PRL responses to CMI in patients with mania and depression suggest that serotonergic functioning in mania and depression is similarly impaired, at least at the level of hypothalamus-hypophysis... - Hormonal responses to clonidine and urinary MHPG in delusional and nondelusional melancholic patients: a placebo-controlled studyL Lykouras
Department of Psychiatry, University of Athens, Eginition Hospital, Greece
Eur Arch Psychiatry Clin Neurosci 241:77-81. 1991..Delusional melancholic patients tended to have smaller GH responses to clonidine than nondelusionals (F = 2.18, P = 0.06). There were no differences in GH response to clonidine between high and low MHPG excretors... - Administration of citalopram before ECT: seizure duration and hormone responsesY G Papakostas
Department of Psychiatry, Athens University Medical School, Greece
J ECT 16:356-60. 2000.... - Sex hormones and biogenic amine turnover of sex offenders in relation to their temperament and character dimensionsOrestis Giotakos
Psychiatric Department, Athens University Medical School, Eginition Hospital, 2 Erifilis str, 11634 Athens, Greece
Psychiatry Res 127:185-93. 2004..In addition, low serotonin turnover and low dopamine turnover seem to be associated with a passive-avoidant behavioral style in rapists and child molesters, respectively... - Gonadal axis hormones in psychiatric male patients after a suicide attemptJohn Tripodianakis
Dept of Psychiatry, Evangelismos General Hospital, Athens, Greece
Eur Arch Psychiatry Clin Neurosci 257:135-9. 2007..Nevertheless, the findings differentiate suicidal behavior from other aggressive/violent behaviors and do not support the notion that suicidal and aggressive behaviors are manifestations of the same impulse... - Changes in central serotonergic function as a correlate of duration of illness in paranoid schizophreniaElias K Angelopoulos
Athens University, Medical School, Psychiatric Clinic, Eginition Hospital, Vas Sophias 74, Athens 115 28, Greece
Psychiatry Res 110:9-17. 2002..The results provide evidence that the persistence of psychotic psychopathology induces secondary neuroadaptive effects, which seem to involve changes in central serotonergic function... - Biogenic amine turnover and serum cholesterol in suicide attemptJohn Tripodianakis
Evangelismos General Hospital, Psychiatric Department, Athens, Greece
Eur Arch Psychiatry Clin Neurosci 252:38-43. 2002..Whether this activation precedes or follows the attempt because of the specific stress, can not be answered at present... - Platelet monoamine oxidase, plasma dopamine beta-hydroxylase activity, dementia and family history of alcoholism in chronic alcoholicsE Lykouras
Department of Psychiatry, Athens University Medical School, Eginition Hospital, Greece
Acta Psychiatr Scand 80:487-91. 1989..Platelet MAO was significantly lower in the alcoholic group. Both enzyme activities were negatively related to the presence of dementia, while low MAO activity was associated with positive family history (parents, sibs) of alcoholism... - Head-up tilt test with clomipramine challenge in vasovagal syndrome--a new tilt testing protocolG N Theodorakis
Onassis Cardiac Surgery Center, 2nd Department of Cardiology and Laboratory of Neurochemistry, Eginition Hospital, Athens University Medical School, Greece
Eur Heart J 24:658-63. 2003..The aim of the study was to randomly compare clomipramine, used as a challenge-agent during head-up tilt test, with isoproterenol, used in the conventional test, in patients with vasovagal syndrome... - The notion of "Sisyphus task" in medicine: A reconstructionY G Papakostas
a Department of Psychiatry, Medical School, Athens University, Eginition Hospital, Athens
Psychiatrike 19:330-6. 2008..Conceptualizing with Sisyphean terms their function, physicians can celebrate their transient victories, and by realizing their limitations, reconstruct their aspirations without decreasing their efforts... - Aggression, impulsivity, plasma sex hormones, and biogenic amine turnover in a forensic population of rapistsOrestis Giotakos
Psychiatric Department of the General Army Hospital, Tripolis, and Prison of Tripolis, Greece
J Sex Marital Ther 29:215-25. 2003..Nevertheless, aggression-impulsivity scores were clearly associated with luteinizing hormone levels. This association may indicate a hyperactive hypothalamic-pituitary-gonadal axis, possibly the result of a reduced serotonergic activity...