Research Topics
| Emanuel K ManesisSummaryAffiliation: University of Athens Country: Greece Publications
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Detail Information
Publications
Hepatitis B surface antigen: relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis BEmanuel K Manesis
Division of Internal Medicine, Athens University Medical School, Athens, Greece
J Hepatol 55:61-8. 2011....
Natural course of treated and untreated chronic HCV infection: results of the nationwide Hepnet.Greece cohort studyE K Manesis
Liver Unit, Euroclinic, Athens, Greece
Aliment Pharmacol Ther 29:1121-30. 2009..The effect of such treatments on the natural course of CHC has been evaluated in small clinical trials with conflicting results...
Quantitative analysis of hepatitis D virus RNA and hepatitis B surface antigen serum levels in chronic delta hepatitis improves treatment monitoringEmanuel K Manesis
Academic Department of Medicine, Hippokration General Hospital, Athens, Greece
Antivir Ther 12:381-8. 2007..Treatment of chronic delta hepatitis is long and difficult and better monitoring is needed...
Prediction of treatment-related HBsAg loss in HBeAG-negative chronic hepatitis B: a clue from serum HBsAg levelsEmanuel K Manesis
Academic Department of Medicine, Hippokration General Hospital, Athens, Greece
Antivir Ther 12:73-82. 2007..Quantification of HBsAg in serum may be of clinical importance in predicting HBsAg seroconversion and complete response to treatment...
The burden and recent epidemiological changes of the main chronic liver diseases in a Greek referral tertiary centreIoannis P Giannousis
Second Department of Internal Medicine, Athens University Medical School, Hipppokration General Hospital, Athens 115 27, Greece
Eur J Gastroenterol Hepatol 22:172-9. 2010..To investigate the burden and recent epidemiological changes of the main chronic liver diseases in a Greek referral tertiary centre...
Serum apoptotic caspase activity in chronic hepatitis C and nonalcoholic Fatty liver diseaseGeorge V Papatheodoridis
Department of Internal Medicine, Athens University Medical School, Hippokration General Hospital of Athens, 114 Vas Sophias Ave, 115 27 Athens, Greece
J Clin Gastroenterol 44:e87-95. 2010..Apoptotic caspases are substantially activated in liver and serum caspase activity has been suggested as a marker of early liver injury...
Is there a meaningful serum hepatitis B virus DNA cutoff level for therapeutic decisions in hepatitis B e antigen-negative chronic hepatitis B virus infection?George V Papatheodoridis
2nd Department of Internal Medicine, Athens University Medical School, Hippokration General Hospital of Athens, Athens, Greece
Hepatology 48:1451-9. 2008..In contrast, minimal histological lesions are observed in the majority of HBeAg-negative patients with persistently normal ALT and HBV DNA >2,000 IU/mL, who may not require immediate liver biopsy and treatment but only close follow-up...
Serum adipokine levels in chronic liver diseases: association of resistin levels with fibrosis severityEmmanuel Tsochatzis
Second Department of Internal Medicine, Athens University Medical School, Hippokration General Hospital, Athens, Greece
Scand J Gastroenterol 43:1128-36. 2008..The objective of this study was to investigate serum levels of the above three adipokines in relation to the etiology of liver disease and to determine their associations with histological severity...
Effect of antiviral therapy on the immunohistochemical expression of bcl-xL and bax protein in patients with HBeAg-negative chronic hepatitis BEvangelos Cholongitas
2nd Department of Internal Medicine, Hippokration General Hospital, National University of Athens School of Medicine, Athens, Greece
J Med Virol 83:1165-71. 2011..In patients without substantial histological changes, treatment seems to increase the apoptosis of hepatocytes, thus having a possible protective effect on hepatocarcinogenesis...
Long-term adefovir plus lamivudine therapy does not decrease creatinine clearance in HBeAg-negative chronic hepatitis B patientsSpilios Manolakopoulos
2nd Academic Department of Internal Medicine, Hippokration Hospital of Athens, Athens, Greece
Liver Int 31:1525-32. 2011..As there are concerns about potential nephrotoxicity of nucleotide analogues, we evaluated renal function parameters during long-term adefovir and lamivudine combination therapy...
Significance of hepatitis B viremia levels determined by a quantitative polymerase chain reaction assay in patients with hepatitis B e antigen-negative chronic hepatitis B virus infectionEmanuel K Manesis
Academic Department of Medicine, Hippokration General Hospital, Athens, Greece
Am J Gastroenterol 98:2261-7. 2003....
Changes of liver and muscle enzymes activity in patients with rigorNikolaos Sevastos
2nd Department of Internal Medicine, National University of Athens Medical School, Hippokration General Hospital, 114 Vas Sophias Ave, 11527 Athens, Greece
Eur J Intern Med 19:109-14. 2008..We investigated whether changes of liver and muscle enzymes activity are associated with rigor of several causes and have any prognostic significance...
Hepatic steatosis in genotype 4 chronic hepatitis C is mainly because of metabolic factorsEmmanuel Tsochatzis
2nd Department of Internal Medicine, Athens University Medical School, Hippokration General Hospital, Athens, Greece
Am J Gastroenterol 102:634-41. 2007..We determined the parameters associated with steatosis in 350 chronic hepatitis C patients, focusing on genotype 4...
Aspartate aminotransferase to platelet ratio index for fibrosis evaluation in chronic viral hepatitisNikolaos V Chrysanthos
2nd Department of Internal Medicine, Medical School of Athens University, Athens, Greece
Eur J Gastroenterol Hepatol 18:389-96. 2006..CONCLUSIONS: APRI is significantly associated with the extent of fibrosis, but it does not classify correctly 40-65% of patients with chronic hepatitis C or HBeAg-negative chronic hepatitis B, and thus it cannot replace liver biopsy...
Virological suppression does not prevent the development of hepatocellular carcinoma in HBeAg-negative chronic hepatitis B patients with cirrhosis receiving oral antiviral(s) starting with lamivudine monotherapy: results of the nationwide HEPNET. Greece cGeorge V Papatheodoridis
2nd Department of Internal Medicine, Athens University Medical School, Hippokration General Hospital, Athens, Greece
Gut 60:1109-16. 2011..To evaluate the risk and predictors of hepatocellular carcinoma (HCC) in HBeAg-negative chronic hepatitis B patients of the large HEPNET.Greece cohort study who received long-term oral antivirals starting with lamivudine monotherapy...
Thrombotic thrombocytopenic purpura with fatal outcome in a patient with chronic hepatitis C treated with pegylated interferon-a/2bMelanie Deutsch
Academic Department of Internal Medicine, Hippokration General Hospital, Athens, Greece
Scand J Gastroenterol 42:408-9. 2007
Cholestasis in acute stroke: an investigation on its prevalence and etiologyNikolaos Sevastos
Academic Department of Medicine, Hippokration General Hospital, Athens, Greece
Scand J Gastroenterol 40:862-6. 2005..Cholestasis is associated with deeper coma, autonomic and hypothalamic involvement and common bile duct dilatation without obstruction, possibly related to inordinate hypertonia of the sphincter of Oddi...
Liver involvement in acute vaso-occlusive crisis of sickle cell disease: prevalence and predisposing factorsJohn Koskinas
Academic Department of Medicine, Hippokration General Hospital, 114 Vas Sophias Avenue, GR 11527 Athens, Greece
Scand J Gastroenterol 42:499-507. 2007..To study the prevalence and predisposing factors of liver involvement in sickle cell disease (SCD) of patients with acute vaso-occlusive crisis...
Serum hepatitis B virus-DNA cutoff levels in hepatitis B e antigen-negative chronic hepatitis B virus infectionGeorge V Papatheodoridis
Hepatology 46:606-7; author reply 607. 2007
HBeAg-negative chronic hepatitis B: from obscurity to prominenceEmanuel K Manesis
J Hepatol 45:343-6. 2006
Serum HBV-DNA levels in inactive hepatitis B virus carriersEmanuel K Manesis
Gastroenterology 122:2092-3; author reply 2093. 2002
