Dimitris Loukopoulos

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint Chronic myeloid leukaemia with marked thrombocytosis in a patient with thalassaemia major: complete haematological remission under the combination of hydroxyurea and anagrelide
    Ersi Voskaridou
    Unit of Thalassaemia, Laikon General Hospital, Athens, Greece
    Br J Haematol 116:155-7. 2002
  2. ncbi request reprint Concordant fetal hemoglobin response to hydroxyurea in siblings with sickle cell disease
    Martin H Steinberg
    Boston University School of Medicine, Room 211, 88 E Newton Street, Boston, MA 02118, USA
    Am J Hematol 72:121-6. 2003
  3. ncbi request reprint Reduction of the clinical severity of sickle cell/beta-thalassemia with hydroxyurea: the experience of a single center in Greece
    D Loukopoulos
    First Department of Medicine, University of Athens, 115 27 Athens, Greece
    Blood Cells Mol Dis 26:453-66. 2000
  4. ncbi request reprint Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures
    P Marianna
    First Department of Medicine, University of Athens, Laikon Hospital, Greece
    Haematologica 86:700-5. 2001
  5. ncbi request reprint Functional role of the four different types of (AT)(x)T(y) motifs 5' to the beta-globin gene and their distribution in the Greek population
    Vassiliki Kalotychou
    First Department of Medicine, University of Athens School of Medicine, Greece
    Blood Cells Mol Dis 28:39-46. 2002
  6. ncbi request reprint Deferiprone as an oral iron chelator in sickle cell disease
    Ersi Voskaridou
    Thalassemia Center, Laikon General Hospital, 16 Sevastoupoleos Street, 11526, Athens, Greece
    Ann Hematol 84:434-40. 2005
  7. doi request reprint The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)
    Ersi Voskaridou
    Thalassemia Center, Laikon General Hospital, GR 11526 Athens, Greece
    Blood 115:2354-63. 2010
  8. doi request reprint Increased CD177 (PRV1) expression in thalassaemia and the underlying erythropoietic activity
    Katerina Zoi
    Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece
    Br J Haematol 141:100-4. 2008
  9. ncbi request reprint Magnetic resonance imaging in the evaluation of iron overload in patients with beta thalassaemia and sickle cell disease
    Ersi Voskaridou
    Thalassaemia Centre, Laikon General Hospital, 16 Sevastoupoleos Street, GR 11526 Athens, Greece
    Br J Haematol 126:736-42. 2004
  10. ncbi request reprint Pamidronate is an effective treatment for osteoporosis in patients with beta-thalassaemia
    Ersi Voskaridou
    Thalassaemia Centre, Laikon General Hospital, Athens, Greece
    Br J Haematol 123:730-7. 2003

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Chronic myeloid leukaemia with marked thrombocytosis in a patient with thalassaemia major: complete haematological remission under the combination of hydroxyurea and anagrelide
    Ersi Voskaridou
    Unit of Thalassaemia, Laikon General Hospital, Athens, Greece
    Br J Haematol 116:155-7. 2002
    ..The administration of hydroxyurea was also associated with a significant HbF increase...
  2. ncbi request reprint Concordant fetal hemoglobin response to hydroxyurea in siblings with sickle cell disease
    Martin H Steinberg
    Boston University School of Medicine, Room 211, 88 E Newton Street, Boston, MA 02118, USA
    Am J Hematol 72:121-6. 2003
    ..Our results provide additional evidence that some elements that regulate HbF expression are linked to the beta-globin gene cluster...
  3. ncbi request reprint Reduction of the clinical severity of sickle cell/beta-thalassemia with hydroxyurea: the experience of a single center in Greece
    D Loukopoulos
    First Department of Medicine, University of Athens, 115 27 Athens, Greece
    Blood Cells Mol Dis 26:453-66. 2000
    ....
  4. ncbi request reprint Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures
    P Marianna
    First Department of Medicine, University of Athens, Laikon Hospital, Greece
    Haematologica 86:700-5. 2001
    ..In this study we tested the effect of valproic acid and trichostatin, alone or in combination with hemin, on gamma chain synthesis in human erythroid liquid cultures...
  5. ncbi request reprint Functional role of the four different types of (AT)(x)T(y) motifs 5' to the beta-globin gene and their distribution in the Greek population
    Vassiliki Kalotychou
    First Department of Medicine, University of Athens School of Medicine, Greece
    Blood Cells Mol Dis 28:39-46. 2002
    ..On the basis of these results, we postulate that the (AT)9T5 and (AT)11T3 variants residing 0.5 kb 5' to the -globin gene do not represent simple polymorphisms and can affect its expression in an erythroid environment...
  6. ncbi request reprint Deferiprone as an oral iron chelator in sickle cell disease
    Ersi Voskaridou
    Thalassemia Center, Laikon General Hospital, 16 Sevastoupoleos Street, 11526, Athens, Greece
    Ann Hematol 84:434-40. 2005
    ..These results suggest that deferiprone may effectively decrease the iron deposition in patients with SCD; moreover, T2 MRI proves to be a reliable and rapid, noninvasive method for assessing the liver iron load in patients with SCD...
  7. doi request reprint The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)
    Ersi Voskaridou
    Thalassemia Center, Laikon General Hospital, GR 11526 Athens, Greece
    Blood 115:2354-63. 2010
    ..These results highlight the beneficial effect of HU, which seems to modify the natural history of SCD and raise the issue of expanding its use in all SCD patients...
  8. doi request reprint Increased CD177 (PRV1) expression in thalassaemia and the underlying erythropoietic activity
    Katerina Zoi
    Haematology Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece
    Br J Haematol 141:100-4. 2008
    ..Within this context, elevated CD177 expression is not only a specific feature of PV but may be an indicator of increased erythropoietic activity in thalassaemia syndromes...
  9. ncbi request reprint Magnetic resonance imaging in the evaluation of iron overload in patients with beta thalassaemia and sickle cell disease
    Ersi Voskaridou
    Thalassaemia Centre, Laikon General Hospital, 16 Sevastoupoleos Street, GR 11526 Athens, Greece
    Br J Haematol 126:736-42. 2004
    ....
  10. ncbi request reprint Pamidronate is an effective treatment for osteoporosis in patients with beta-thalassaemia
    Ersi Voskaridou
    Thalassaemia Centre, Laikon General Hospital, Athens, Greece
    Br J Haematol 123:730-7. 2003
    ..These data suggest that pamidronate, at a monthly dose of 30 mg, is an effective treatment for thalassaemic osteoporosis...
  11. ncbi request reprint Danazol therapy for thrombocytopenia in patients with myelodysplastic syndromes
    Nora Viniou
    First Department of Internal Medicine, University of Athens School of Medicine, Laikon General Hospital, Athens, Greece
    Acta Haematol 107:234-6. 2002
  12. ncbi request reprint Leukemogenic risk of hydroxyurea therapy as a single agent in polycythemia vera and essential thrombocythemia: N- and K-ras mutations and microsatellite instability in chromosomes 5 and 7 in 69 patients
    Despina Mavrogianni
    First Department of Internal Medicine, Laikon General Hospital, University of Athens, Greece
    Int J Hematol 75:394-400. 2002
    ....
  13. ncbi request reprint Acute Aspergillosis gastritis in a case of fatal aplastic anemia
    Kostas Konstantopoulos
    First Department of Medicine, Athens University Medical School, Greece
    Scand J Infect Dis 34:148-9. 2002
    ..A rare case of stomach perforation following acute aspergillosis gastritis in the course of a fatal severe aplastic anemia is reported...
  14. ncbi request reprint Clonal analysis of granulocyte-monocyte colony-forming unit cells with the human androgen receptor gene in chronic myeloid leukemia
    Salem Akel
    First Department of Medicine, University of Athens School of Medicine, Athens, Greece
    Int J Hematol 77:476-81. 2003
    ....
  15. ncbi request reprint Analysis of the A(TA)(n)TAA configuration in the promoter region of the UGT1 A1 gene in Greek patients with thalassemia intermedia and sickle cell disease
    Vassiliki Kalotychou
    First Department of Medicine, University of Athens School of Medicine, Laikon General Hospital, 11527, Athens, Greece
    Blood Cells Mol Dis 31:38-42. 2003
    ....
  16. ncbi request reprint Factors mediating lipofection potency of a series of cationic phosphonolipids in human cell lines
    Daphne Koumbi
    First Department of Medicine, University of Athens, School of Medicine, Athens, Greece
    Biochim Biophys Acta 1760:1151-9. 2006
    ..Human A gamma- and epsilon-globin transgene nuclear incorporation and expression in 5637 cells post GLB.391-mediated lipofection lends credence to its use as a vehicle of therapeutic transgene delivery...
  17. pmc Haemoglobinopathies in Greece: prevention programme over the past 35 years
    Dimitris Loukopoulos
    University of Athens and Biomedical Research Foundation of the Academy of Athens, Athens, Greece
    Indian J Med Res 134:572-6. 2011
    ....
  18. ncbi request reprint Arthropathy in juvenile hemochromatosis
    George Vaiopoulos
    University of Athens Medical School, Athens, Greece
    Arthritis Rheum 48:227-30. 2003
    ..To evaluate whether arthropathy is associated with juvenile hemochromatosis and, if so, to assess the relationship between this feature and other clinical features of the disease...
  19. ncbi request reprint Elastic tissue abnormalities resembling pseudoxanthoma elasticum in beta thalassemia and the sickling syndromes
    Athanasios Aessopos
    First Department of Internal Medicine, University of Athens, School of Medicine, Laiko General Hospital, Athens, Greece
    Blood 99:30-5. 2002
    ..Because several organ systems are involved, each medical specialty should be aware of the phenomenon. This coexistence, on the other hand, introduces a novel pathogenetic aspect of PXE and an important research challenge...
  20. ncbi request reprint Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
    Antonella Roetto
    Department of Clinical and Biological Sciences, University of Torino, Azienda Ospedaliera San Luigi, 10043 Orbassano, Torino, Italy
    Nat Genet 33:21-2. 2003
    ..Here we report the identification of two mutations (93delG and 166C-->T) in HAMP on 19q13 in two families with a new type of juvenile hemochromatosis...