Evi S Lianidou
Affiliation: University of Athens
- Parisi C, Mastoraki S, Markou A, Strati A, Chimonidou M, Georgoulias V, et al. Development and validation of a multiplex methylation specific PCR-coupled liquid bead array for liquid biopsy analysis. Clin Chim Acta. 2016;461:156-64 pubmed publisher..The main principle of the developed methodology has the potential to be extended in a large number of gene-targets and be applied in many types of cancer. ..
- Mastoraki S, Strati A, Tzanikou E, Chimonidou M, Politaki E, Voutsina A, et al. ESR1 Methylation: A Liquid Biopsy-Based Epigenetic Assay for the Follow-up of Patients with Metastatic Breast Cancer Receiving Endocrine Treatment. Clin Cancer Res. 2018;24:1500-1510 pubmed publisher..i>ESR1 methylation should be further evaluated as a potential liquid biopsy-based biomarker. Clin Cancer Res; 24(6); 1500-10. Â©2017 AACR. ..
- Markou A, Lazaridou M, Paraskevopoulos P, Chen S, Swierczewska M, Budna J, et al. Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients. Clin Chem. 2018;64:297-306 pubmed publisher..The combination of in vivo CTC isolation with downstream RNA analysis is highly promising as a high-throughput, specific, and ultrasensitive approach for multiplex liquid biopsy-based molecular diagnostics. ..
- Dimitrakopoulos L, Vorkas P, Georgoulias V, Lianidou E. A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of CST6 promoter methylation in clinical samples. BMC Cancer. 2012;12:486 pubmed publisher..It gives comparable results to MSP in less time, while it offers the advantage of additionally providing an estimation of the level of methylation. ..