A Ch Lazaris

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi Markers of drug resistance in relapsing colon cancer
    A C Lazaris
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, 75 Mikras Asias Street, Goudi, 115 27 Athens, Greece
    J Cancer Res Clin Oncol 128:114-8. 2002
  2. ncbi Lectin histochemistry as a predictor of dysplasia grade in colorectal adenomas
    A C Lazaris
    The Athens National University Medical Faculty, Department of Anatomic Pathology 75 Mikras Asias Str, Goudi, Athens, GR 115 27, Greece
    Pathol Oncol Res 6:265-71. 2000
  3. ncbi Histological diagnosis of cutaneous "warty" carcinoma on a pre-existing HPV lesion
    K Aroni
    Department of Pathology, The Athens National University Medical School, Greece
    Acta Derm Venereol 80:294-6. 2000
  4. ncbi Correlation of tumor markers p53, bcl-2 and cathepsin-D with clinicopathologic features and disease-free survival in laryngeal squamous cell carcinoma
    A C Lazaris
    Department of Pathology, The Athens National University, Medical School, Athens, Greece
    Pathol Int 50:717-24. 2000
  5. ncbi Congenital epulis: an ultrastructural and immunohistochemical case study
    A C Lazaris
    Department of Anatomic Pathology, Medical School, The Athens National and Kapodistrian University of Athens, Greece
    Adv Clin Path 4:159-63. 2000
  6. ncbi A comparative study of the int-2 gene product in primary and secondary parathyroid lesions
    Sofia Tseleni-Balafouta
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Athens, Greece
    Eur J Endocrinol 146:57-60. 2002
  7. ncbi Signet ring basal cell carcinoma. A case study emphasizing the differential diagnosis of neoplasms with signet ring cell formation
    K Aroni
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Greece
    Pathol Res Pract 197:853-6. 2001
  8. ncbi Sweat gland carcinoma with multiple local recurrences: a case report
    D Panoussopoulos
    Department of Propaedeutic Surgery, Hippokrateion General Hospital of Athens, Athens, GR 10676, Greece
    Adv Clin Path 3:63-8. 1999
  9. ncbi Immunodetection and clinico-pathological correlates of two tumour growth regulators in laryngeal carcinoma
    A Ch Lazaris
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Greece
    Histol Histopathol 17:131-8. 2002
  10. ncbi A solitary cutaneous tumor with distinct areas of verruca and seborrheic keratosis-like lesion
    A C Lazaris
    The Medical School of the Athens National University, Department of Anatomic Pathology 75 Mikras Asias Str, Goudi, Athens, GR 115 27, Greece
    Pathol Oncol Res 5:320-3. 1999

Collaborators

Detail Information

Publications48

  1. ncbi Markers of drug resistance in relapsing colon cancer
    A C Lazaris
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, 75 Mikras Asias Street, Goudi, 115 27 Athens, Greece
    J Cancer Res Clin Oncol 128:114-8. 2002
    ..e., P-glycoprotein, MRP, and LRP) and of topoisomerase IIalpha in a series of 20 primary colon carcinomas and their recurrences...
  2. ncbi Lectin histochemistry as a predictor of dysplasia grade in colorectal adenomas
    A C Lazaris
    The Athens National University Medical Faculty, Department of Anatomic Pathology 75 Mikras Asias Str, Goudi, Athens, GR 115 27, Greece
    Pathol Oncol Res 6:265-71. 2000
    ....
  3. ncbi Histological diagnosis of cutaneous "warty" carcinoma on a pre-existing HPV lesion
    K Aroni
    Department of Pathology, The Athens National University Medical School, Greece
    Acta Derm Venereol 80:294-6. 2000
    ..e. koilocytotic atypia). It is worth noting that cutaneous location of such a warty carcinoma is very rare...
  4. ncbi Correlation of tumor markers p53, bcl-2 and cathepsin-D with clinicopathologic features and disease-free survival in laryngeal squamous cell carcinoma
    A C Lazaris
    Department of Pathology, The Athens National University, Medical School, Athens, Greece
    Pathol Int 50:717-24. 2000
    ..0395). Although the classical prognostic factors of laryngeal carcinoma retain their predominance, cathepsin-D immunoreactivity may serve as an additional prognosticator in specific patient subgroups...
  5. ncbi Congenital epulis: an ultrastructural and immunohistochemical case study
    A C Lazaris
    Department of Anatomic Pathology, Medical School, The Athens National and Kapodistrian University of Athens, Greece
    Adv Clin Path 4:159-63. 2000
    ..The characteristic electron microscopy findings, as well as other features of epulis in relation to the theories for its possible origin are also reviewed..
  6. ncbi A comparative study of the int-2 gene product in primary and secondary parathyroid lesions
    Sofia Tseleni-Balafouta
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Athens, Greece
    Eur J Endocrinol 146:57-60. 2002
    ..Primary and secondary hyperparathyroidism have no clear differences with regard to the histopathological features of the diseased parathyroid glands...
  7. ncbi Signet ring basal cell carcinoma. A case study emphasizing the differential diagnosis of neoplasms with signet ring cell formation
    K Aroni
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Greece
    Pathol Res Pract 197:853-6. 2001
    ..Because of potential diagnostic difficulties, the pathologist should be aware of this unusual form of basal cell carcinoma. A brief review of the literature on the differential diagnosis of signet ring cell cutaneous tumors is presented...
  8. ncbi Sweat gland carcinoma with multiple local recurrences: a case report
    D Panoussopoulos
    Department of Propaedeutic Surgery, Hippokrateion General Hospital of Athens, Athens, GR 10676, Greece
    Adv Clin Path 3:63-8. 1999
    ..The neoplasm relapsed locally thrice in a period of 10 years; however, distant metastases were not found. The differential diagnosis of sweat gland tumors is discussed in the present article...
  9. ncbi Immunodetection and clinico-pathological correlates of two tumour growth regulators in laryngeal carcinoma
    A Ch Lazaris
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Greece
    Histol Histopathol 17:131-8. 2002
    ..Whether the latter can be used for the identification of immortalized cells in every-day practice is worth investigating...
  10. ncbi A solitary cutaneous tumor with distinct areas of verruca and seborrheic keratosis-like lesion
    A C Lazaris
    The Medical School of the Athens National University, Department of Anatomic Pathology 75 Mikras Asias Str, Goudi, Athens, GR 115 27, Greece
    Pathol Oncol Res 5:320-3. 1999
    ..In the verrucous component p53 protein was overexpressed and, additionally, increased Ki-67 immunopositive signals were detected, being localized below the HPV-DNA-expressing spinous cells...
  11. ncbi Ischaemic necrosis of the rectum and sigmoid colon complicating systemic lupus erythematosus
    A Ch Lazaris
    Department of Pathology, Athens National and Kapodistrian University Medical Faculty, 75 Mikras Asias Str, Goudi, GR 115 27, Athens, Greece
    Acta Gastroenterol Belg 66:191-4. 2003
    ....
  12. ncbi Immunohistochemical assessment of basement membrane components in colorectal cancer: prognostic implications
    A Ch Lazaris
    Department of Pathology, School of Medicine, The National and Capodistrian University of Athens, Athens, Greece
    J Exp Clin Cancer Res 22:599-606. 2003
    ..The total loss or considerable discontinuity of the basement membranes of cancerous cells can be considered as indicators of tumour aggressiveness...
  13. ncbi Tissue evaluation of immune markers in endometrial and cervical carcinomas
    A Ch Lazaris
    Dept of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
    J Exp Clin Cancer Res 23:269-75. 2004
    ..This activation appears to be an early event in the evolution of invasive endometrial and cervical carcinomas...
  14. ncbi Prognostic predictors of gastrointestinal stromal tumors: a multi-institutional analysis of 102 patients with definition of a prognostic index
    K Kontogianni
    Department of Pathology, The National and Capodistrian University of Athens, School of Medicine, 75 M Asias St, 115 25, Goudi, Greece
    Eur J Surg Oncol 29:548-56. 2003
    ..The aim of this study is to identify prognostic factors influencing survival in patients with gastrointestinal stromal tumors (GISTs) and to identify a mathematical model that can predict lifetime expectation...
  15. ncbi Deregulation of EGFR/VEGF/HIF-1a signaling pathway in colon adenocarcinoma based on tissue microarrays analysis
    D N Rigopoulos
    Department of Internal Medicine, 401 General Army Hospital, Athens, Greece
    J BUON 15:107-15. 2010
    ..Our aim was to co-evaluate their expression correlated to the hypoxia inducible factor 1alpha (HIF-1a), which activates the transcription of VEGF gene...
  16. ncbi Microsatellite instability in sporadic and inherited colon adenocarcinomas from Greek patients: correlation with several clinicopathological characteristics
    N V Michalopoulos
    Department of Pathology, Medical School, National and Kapodistrian University of Athens, Goudi, Athens, Greece
    Acta Gastroenterol Belg 68:294-301. 2005
    ..The aim of this study was to examine the presence of microsatellite instability in relation to other commonly observed genetic abnormalities and clinicopathological characteristics of sporadic and inherited colorectal cancers...
  17. ncbi Histological assessment of apoptotic cell death in cardiomyopathies
    N G Kavantzas
    Department of Pathology, School of Medicine, National University of Athens, Greece
    Pathology 32:176-80. 2000
    ..It is evident that apoptosis constitutes a major biological phenomenon in the development of at least some heart diseases, but its role in their pathophysiology has yet to be delineated...
  18. ncbi Immunohistochemical expression of caspase-3 as an adverse indicator of the clinical outcome in human breast cancer
    L Nakopoulou
    Department of Pathology, School of Medicine, National and Capodistrian University of Athens, Greece
    Pathobiology 69:266-73. 2001
    ..The aim of this study was to examine the relation of the immunohistochemical expression of caspase-3 in 137 infiltrating breast carcinomas to patients' clinicopathological parameters and survival...
  19. ncbi Evaluation of neuroendocrine staining and androgen receptor expression in incidental prostatic adenocarcinoma: prognostic implications
    V E Theodoropoulos
    Department of Urology, Agia Olga General Hospital, Athens, Greece
    Urology 66:897-902. 2005
    ..Neuroendocrine cells may exert a dynamic role in the microenvironment of PCa. The AR is thought to have a central role in the propagation of prostate carcinogenesis...
  20. ncbi Topoisomerase I protein expression in primary colorectal cancer and recurrences after 5-FU-based adjuvant chemotherapy
    P Gouveris
    Medical Oncology Unit, Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
    J Cancer Res Clin Oncol 133:1011-5. 2007
    ..Our aim was to investigate whether chemotherapy with 5-FU induces an alteration in the levels of topoisomerase I (topo I) in colorectal neoplastic tissues..
  21. ncbi Nuclear/Nucleolar morphometry and DNA image cytometry as a combined diagnostic tool in pathology of prostatic carcinoma
    N Kavantzas
    Dept of Pathology, Medical School, National University of Athens, Greece
    J Exp Clin Cancer Res 20:537-42. 2001
    ..Morphonuclear evidence of anaplasia and DNA aneuploidy may be used as diagnostic tools in prostate cancer in addition to Gleason grade...
  22. ncbi Tissue immunodetection of c100 hepatitis C virus antigen in major thalassemic patients
    L Nakopoulou
    Department of Pathology, Athens University Medical School, Greece
    Hepatogastroenterology 46:2515-20. 1999
    ..To determine the significance of hepatic expression of hepatitis C viral antigen c100, an immunohistochemical assay was performed in 113 young thalassemics with chronic HCV infection...
  23. ncbi An immunohistochemical analysis of angiogenesis in invasive breast cancer with correlations to clinicopathologic predictors
    L Nakopoulou
    Department of Pathology, Athens University Medical School, Greece
    Anticancer Res 19:4547-53. 1999
    ..There is evidence that angiogenesis plays an important role in the biologic aggressiveness of breast carcinomas and might be used as a prognostic marker...
  24. ncbi Significance of nuclear morphometry as a diagnostic tool in fine-needle aspirates of the liver
    H Koutselini
    Department of Pathology, Medical School, National University of Athens, Greece
    Eur J Gastroenterol Hepatol 12:913-21. 2000
    ..Our aim was to determine the value of computerized interactive nuclear morphometry in the preoperative prediction of primary or metastatic malignancy as opposed to non-malignant lesions, in fine-needle aspirates (FNA) of hepatic lesions...
  25. ncbi The nuclear morphometry by image analysis in the histopathologic diagnosis of lung cancer
    N Kavantzas
    Dept of Pathology, Medical School, National University of Athens, Greece
    J Exp Clin Cancer Res 19:201-6. 2000
    ..So, the latter nuclear parameter may be used as a complementary tool in the histopathologic differential diagnosis of lung cancer...
  26. ncbi DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer
    L Nakopoulou
    Department of Pathology, Medical School, The National and Kapodistrian University of Athens, 75 Mikras Assias Street, Goudi, GR 115 Athens, Greece
    Pathobiology 68:137-43. 2000
    ..The aim of this study was to examine the relationship between the expression of topo IIalpha and biological behavior markers in breast cancer...
  27. pmc Predictive value of topoisomerase II alpha immunostaining in urothelial bladder carcinoma
    L Nakopoulou
    Department of Pathology, Athens National University School of Medicine, 75 Mikras Asias Str, Goudi, GR 115 27 Athens, Greece
    J Clin Pathol 54:309-13. 2001
    ..The aim of this study was to examine the relation of the expression of topo II alpha to the biological behaviour of conventional urinary bladder cancer...
  28. ncbi MMP-3 mRNA and MMP-3 and MMP-1 proteins in bladder cancer: a comparison with clinicopathologic features and survival
    L Nakopoulou
    Department of Pathology, Medical School, The National and Kapodistrian University of Athens, Greece
    Appl Immunohistochem Mol Morphol 9:130-7. 2001
    ....
  29. ncbi Genetic alterations involved in the development of gallbladder carcinomas from Greek patients
    A Saetta
    Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
    Hepatogastroenterology 48:1284-8. 2001
    ..The genetic pathways of gallbladder cancer are not yet well defined since the contribution of genetic abnormalities clarified in other organs remains questionable...
  30. ncbi The favorable prognostic impact of tissue inhibitor of matrix metalloproteinases-1 protein overexpression in breast cancer cells
    L Nakopoulou
    Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
    APMIS 111:1027-36. 2003
    ..TIMP1 overexpression in cancer cells appears for the first time to be a promising indicator of favorable prognosis in breast cancer...
  31. pmc The favourable prognostic value of oestrogen receptor beta immunohistochemical expression in breast cancer
    L Nakopoulou
    Department of Pathology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Assias Street, Goudi, GR 115 27 Athens, Greece
    J Clin Pathol 57:523-8. 2004
    ..Oestrogen receptor beta (ERbeta) is present in breast tumours, although its prognostic and pathophysiological roles remain to be established...
  32. ncbi Extracellular regulated kinase-2 immunoreactivity increases in parallel with cervical intraepithelial neoplasia grade in cervical neoplasia
    V Kapetanios
    5th Gynaecological Department, Elena Venizelou Maternity Hospital, Athens, Greece
    Int J Gynecol Cancer 18:540-5. 2008
    ..001). In conclusion, our study found a direct relationship between the increasing grade of the dysplastic cervical lesions and the intensity of ERK2 staining, thus implying a role of ERK2 as an early event in cervical carcinogenesis...
  33. ncbi Immunohistochemical detection of cell cycle regulators, Fhit protein and apoptotic cells in parathyroid lesions
    G E Thomopoulou
    Department of Pathology, School of Medicine, The Athens National and Kapodistrian University, Athens, Greece
    Eur J Endocrinol 148:81-7. 2003
    ..We attempted to evaluate the cellular proliferative kinetics and apoptotic function of the parathyroid glands in patients with non-familial hyperparathyroidism (HPT)...
  34. ncbi Papillary serous carcinoma of peritoneum: case study and review of the literature on the differential diagnosis of malignant peritoneal tumors
    H A Koutselini
    Department of Cytopathology, Areteion Hospital, The Athens National and Capodistrian University Medical School, Athens, Greece
    Adv Clin Path 5:99-104. 2001
    ..Differential diagnosis from ovarian cancer was possible only after the pathological examination of the surgically resected ovaries; the tumor showed minimal superficial invasion of the ovarian cortex...
  35. ncbi Epidermal growth factor receptor and proliferating cell nuclear antigen expression in urine ThinPrep specimens
    E N Politi
    Department of Cytopathology, Aretaieion Hospital, The Athens National and Kapodistrian University, Athens, Greece
    Cytopathology 16:303-8. 2005
    ....
  36. ncbi Evaluation of epidermal growth factor receptor gene and chromosome 7 alterations in squamous cell carcinoma of the larynx, using chromogenic in situ hybridization on tissue microarrays
    E Tsiambas
    Department of Pathology, 417 Veterans Administration Hospital NIMTS, Athens, Greece
    J Laryngol Otol 121:563-70. 2007
    ....
  37. pmc Population-based study of human papillomavirus infection and cervical neoplasia in Athens, Greece
    C Kroupis
    Department of Clinical Biochemistry, Medical School, National and Kapodistrian University of Athens, Greece
    Epidemiol Infect 135:943-50. 2007
    ..A clear pattern of decreasing prevalence of HPV with age was also observed. Our results indicate that HPV infections, especially those with HPV-16, represent a significant public health concern in Greece...
  38. doi Evaluation of caspase-3 and caspase-8 deregulation in tongue squamous cell carcinoma, based on immunohistochemistry and computerised image analysis
    D Andressakis
    Department of Oral and Maxillofacial Surgery, St Savas Anticancer Hospital, Athens, Greece
    J Laryngol Otol 122:1213-8. 2008
    ..To investigate the potential role of caspase-3 and caspase-8 protein expression in the biological behaviour of tongue squamous cell carcinoma...
  39. ncbi Adrenaline attenuates the acute lung injury after intratracheal lipopolysaccharide instillation: an experimental study
    G E Philippakis
    Department of Thoracic and Cardiovascular Surgery, Evangelismos General Hospital, Athens, Greece
    Inhal Toxicol 20:445-53. 2008
    ..Our study establishes that systemic adrenaline administration after LPS instillation may ameliorate the inflammatory lung response in vivo...
  40. ncbi Tissue detection of natural killer cells in laryngeal carcinoma
    A C Lazaris
    First Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
    Neoplasma 54:379-82. 2007
    ....
  41. doi Myoepithelial carcinoma of the retromolar area in a young female. A rare case report
    A Chrysovergis
    1st ENT Department, University of Athens Medical School, Hippocrateion General Hospital, Athens, Greece
    Med Oncol 27:946-9. 2010
    ..It is considered a low-grade malignancy; it sometimes shows aggressive behavior and may locally recur. Our patient was treated successfully with wide-local resection and remained free of disease for 6 months...
  42. ncbi Retroperitoneal follicular dendritic cell sarcoma
    A Androulaki
    Department of Pathology, Laiko General Hospital, Mikras, Kapodistrian University of Athens, Athens, Greece
    Int J Hematol 84:2. 2006
  43. ncbi Differential expression of bcl-2 family proteins in bladder carcinomas. Relationship with apoptotic rate and survival
    Penelope Korkolopoulou
    Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
    Eur Urol 41:274-83. 2002
    ..To elucidate the role of various bcl-2 family molecules in the regulation of apoptosis and the progression of urothelial cancer, in relation to standard prognosticators...
  44. ncbi Assessment of JC polyoma virus in colon neoplasms
    George Theodoropoulos
    Propaideutic Surgical Department, Hippocration University Hospital, Athens, Greece
    Dis Colon Rectum 48:86-91. 2005
    ..Controversy arose when another research group did not confirm this association. The purpose of this study was to detect JC virus in a series of colon neoplasms from Greek patients...
  45. ncbi Hypoxia-inducible factor 1 alpha expression correlates with angiogenesis and unfavorable prognosis in bladder cancer
    Vasilios E Theodoropoulos
    Department of Urology, Agia Olga General Hospital, Ag Olgas 3 5, Athens 14233, Greece
    Eur Urol 46:200-8. 2004
    ..We examined the relationship between hypoxia and angiogenesis, as well as their prognostic impact in patients with urothelial bladder cancer...
  46. ncbi Detection of genetic abnormalities in neoplasms from Greek patients with FAP
    Nikolaos V Michalopoulos
    Department of Pathology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Str Goudi, GR 11527, Athens, Greece
    Eur J Surg Oncol 29:38-43. 2003
    ..We report the frequency of microsatellite instability and other genetic abnormalities in a group of Greek patients with FAP, in relation to various clinicopathological variables...
  47. ncbi Evaluation of E-cadherin/catenin complex in primary and secondary glomerulonephritis
    Lydia Nakopoulou
    Department of Pathology, Medical School, The National and Capodistrian University of Athens, Greece
    Am J Kidney Dis 39:469-74. 2002
    ..This expression probably is linked with epithelial cells' responses to various mitogens, such as growth factors...
  48. ncbi Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer
    George Theodoropoulos
    1st Propaideutic Surgical Department, Hippocration University Hospital, University of Athens, Greece
    World J Gastroenterol 12:5037-43. 2006
    ....