Research Topics
Species | S D LadasSummaryAffiliation: University of Athens Country: Greece Publications
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Publications
A three-day octreotide-containing helicobacter pylori eradication therapy for cure of peptic ulcersS D Ladas
Second Department of Internal Medicine, Evangelismos Hospital, Athens University, Greece
Hepatogastroenterology 45:761-4. 1998..The aim of this pilot study was to determine safety and efficacy of an ultra short quadruple octreotide containing H. pylori eradication therapy in patients with peptic ulcer...
An introductory course for training in endoscopySpiros D Ladas
Gastroenterology Unit, Second Department of Internal Medicine, Evangelismos Hospital, Athens University, Athens, Greece
Dig Dis 20:242-5. 2002..Their aim will be to educate skilled endoscopists in the principles of teaching, which should be thoroughly grounded in the ethics of our profession...
Percutaneous endoscopic gastrostomy: adequacy and quality of information given to decision makersS D Ladas
Gastroenterology Unit, 2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, Greece
Dig Dis 20:289-92. 2002..The aims of this retrospective study were to evaluate the quality of information given to the decision-makers (relatives) and determine the overall acceptance of the procedure by the patients' family...
Does recombinant human erythropoietin accelerate correction of post-ulcer-bleeding anaemia? A pilot studySpiros D Ladas
Gastroenterology Unit, 2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, 23 Sisini Street, 115 28 Athens, Greece
World J Gastroenterol 10:586-9. 2004..This prospective, randomised, open, pilot study was designed to investigate whether recombinant human erythropoietin (Epoetin) therapy accelerate haematocrit increase in the post-bleeding recovery period...
Incidence of ulcerative colitis in Central Greece: a prospective studySpiros D Ladas
23 Sisini Street, 11528 Athens, Greece
World J Gastroenterol 11:1785-7. 2005..To study the incidence of ulcerative colitis UC in the prefecture of Trikala, Central Greece...
Banana fibers in colonic mucus may puzzle the endoscopistS D Ladas
Hepato-Gastroenterology Unit, 2nd Department of Internal Medicine, Medical School, Athens University, Athens University General Hospital, Greece
Endoscopy 37:1261. 2005
A novel maneuver for colonic polypectomy at the 6-o'clock positionS D Ladas
Hepatogastroenterology Unit, 2nd Dept. of Internal Medicine, Medical School of Athens University, Attikon University General Hospital, Athens, Greece
Endoscopy 38:434. 2006
Use of sedation for routine diagnostic upper gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy Survey of National Endoscopy Society MembersS D Ladas
European Society of Gastrointestinal Endoscopy, Munich, Germany
Digestion 74:69-77. 2006..The aim of this survey was to investigate the rate of using premedication for routine diagnostic upper gastrointestinal (UGI) endoscopy in endoscopy societies, members of the European Society of Gastrointestinal Endoscopy (ESGE)...
Ethical issues in endoscopy: patient satisfaction, safety in elderly patients, palliation, and relations with industry. Second European Symposium on Ethics in Gastroenterology and Digestive Endoscopy, Kos, Greece, July 2006S D Ladas
European Society of Gastroenterology, Munich, Germany
Endoscopy 39:556-65. 2007
Performance of two immunosorbent assay kits for the detection of serum immunoglobulin G to Helicobacter pylori in untreated greek patientsS D Ladas
2nd Dept of Internal Medicine, Athens University, Evangelismos Hospital, Greece
Scand J Gastroenterol 37:512-6. 2002..We have prospectively evaluated the performance of two commercially available serum enzyme immunoassays (EIA) detecting H. pylori immunoglobulin G (IgG) antibodies in the sera of untreated Greek patients...
Evaluation of a single-step serological assay for laboratory diagnosis of Helicobacter pylori infectionS D Ladas
2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, Greece
Eur J Clin Microbiol Infect Dis 21:56-9. 2002....
Pancreatic tuberculosis in non-immunocompromised patients: reports of two cases, and a literature reviewS D Ladas
Second Department of Internal Medicine, Evangelismos Hospital, Athens University, Greece
Eur J Gastroenterol Hepatol 10:973-6. 1998..It is a curable disease and should be considered in the differential diagnosis of a pancreatic mass or abscess shown on ultrasound or computed tomography, especially in developing countries, where tuberculosis is common...
Factors predicting the possibility of conducting colonoscopy without sedationS D Ladas
Clinic for Gastrointestinal Endoscopy, Athens, Greece
Endoscopy 32:688-92. 2000..The aims of the present study were to determine the percentage of patients who can successfully undergo nonsedated colonoscopy and to identify factors capable of predicting whether a colonoscopy can be completed without sedation...
Prospective evaluation of a whole-blood antibody test (FlexPack HP) for in-office diagnosis of Helicobacter pylori infection in untreated patientsS D Ladas
2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, Greece
Eur J Gastroenterol Hepatol 12:727-31. 2000..Rapid, reliable in-office tests are needed for applying the adopted screen-and-treat strategy in Helicobacter pylori-positive young dyspeptic patients...
Gastric phytobezoars may be treated by nasogastric Coca-Cola lavageSpiros D Ladas
Gastroenterology Unit, 2nd Department of Internal Medicine, Medical School, Athens University, Evangelismos Hospital, 23 Sisini Street, 115 28 Athens, Greece
Eur J Gastroenterol Hepatol 14:801-3. 2002..The dissolution of large gastric phytobezoars with cola nasogastric lavage is a safe, rapid and effective method. Patients may be treated in the medical ward, avoiding therapeutic endoscopy or surgery...
Relationship of Helicobacter pylori CagA(+) status to gastric juice vitamin C levelsT Rokkas
Gastroenterology Unit, Army General Hospital, Athens, Greece
Eur J Clin Invest 29:56-62. 1999..The aim of the present study, therefore, was to study the impact of H. pylori CagA status on gastric juice vitamin C levels...
Informed consent for gastrointestinal endoscopy: a 2002 ESGE surveyK Triantafyllou
Endoscopy Unit, 2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, Athens, Greece
Dig Dis 20:280-3. 2002..Finally, the procedure-related mortality is provided in only 23% (6/26) of countries. CONCLUSION: The procedure of obtaining informed consent for endoscopy varies considerably and may need reevaluation...
The association between CagA status and the development of esophagitis after the eradication of Helicobacter pyloriT Rokkas
Gastroenterology Unit, 401 Army General Hospital, Athens, Greece
Am J Med 110:703-7. 2001..pylori eradication. CONCLUSION: Patients infected with strains of H. pylori that are cagA-positive are at increased risk of developing esophagitis after eradication of H. pylori...
Effectiveness of acid suppression in preventing gastroesophageal reflux disease (GERD) after successful treatment of Helicobacter pylori infectionT Rokkas
Gastroenterology Unit, 401 Army General Hospital, Athens, Greece
Dig Dis Sci 46:1567-72. 2001..0022). The respective values for esophagitis were 0/33 (0%) and 6/35 (17.1%) (P = 0.0083). In conclusion, antisecretory treatment in H. pylori(+) patients, after successful eradication, is effective in preventing GERD...
Dramatic decline of acute appendicitis in Greece over 30 years: index of improvement of socioeconomic conditions or diagnostic aids?A A Papadopoulos
Hepatogastroenterology Unit, 2nd Department of Internal Medicine Propaedeutic, Attikon University Hospital, Medical School, Athens University, Athens, Greece
Dig Dis 26:80-4. 2008..There are several reports showing a continuing fall in the incidence of acute appendicitis in the western countries. Our aim was to study the trend of the incidence of acute appendicitis in the Greek population over 30 years...
Comparison of T- and Z-score in identifying risk factors of osteoporosis in inflammatory bowel disease patientsE Tsironi
Gastroenterology Unit, Attikon University General Hospital, Athens
J Musculoskelet Neuronal Interact 8:79-84. 2008..Since in these studies either T- or Z-scores has been used, our aim was to compare T- and Z-score in identifying risk factors of osteoporosis in IBD patients...
Effectiveness of two quadruple, tetracycline- or clarithromycin-containing, second-line, Helicobacter pylori eradication therapiesS D Georgopoulos
Gastroenterology Unit, 2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, Athens, Greece
Aliment Pharmacol Ther 16:569-75. 2002..4; P=0.036). CONCLUSIONS: Tetracycline-containing quadruple rescue therapy is highly effective in treating H. pylori eradication failures of the omeprazole-amoxicillin-clarithromycin regimen...
European Society of Gastrointestinal Endoscopy (ESGE): recommendations (2009) on clinical use of video capsule endoscopy to investigate small-bowel, esophageal and colonic diseasesS D Ladas
1st and 2nd Departments of Internal Medicine Propaedeutic, Medical School, University of Athens, Athens, Greece
Endoscopy 42:220-7. 2010....
Are gastroenterologists aware of the role of ethics committees?K Triantafyllou
Gastroenterology Unit, 2nd Department of Internal Medicine, Athens University, Evangelismos Hospital, Athens, Greece
Dig Dis 20:271-4. 2002..The aim of this study was to investigate the need to educate endoscopists about the role of the ECs in European and Mediterranean countries...
Argon plasma coagulation has a long-lasting therapeutic effect in patients with chronic radiation proctitisG Karamanolis
Hepatogastroenterology Unit, Second Department of Internal Medicine Propaedeutic, Attikon General Hospital, Athens University, Athens, Greece
Endoscopy 41:529-31. 2009..The study aims were to prospectively evaluate (i) the efficacy of APC in endoscopically mild and severe radiation proctitis, and (ii) the recurrence rate following successful treatment...
Do we present abstracts on ethical, legal, cost-effectiveness and patient care issues at major gastroenterology congresses?E Archavlis
Hepatogastroenterology Unit, 2nd Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, Athens University, Athens, Greece
Dig Dis 26:71-4. 2008..In the era of the new millennium, a lot of preclinical and clinical research is published. However, ethico-legal, cost-effectiveness and patient care issues are not addressed equally...
Accuracy of measurements of the length of esophageal lesions: an experimental studyD Polymeros
Hepato Gastroenterology Unit, Second Propaedeutic Department of Medicine, Medical School, Athens University, Attikon University General Hospital, Athens, Greece
Endoscopy 39:948-51. 2007....
Does purgative preparation influence the diagnostic yield of small bowel video capsule endoscopy?: A meta-analysisT Rokkas
Gastroenterology Clinic, Henry Dunant Hospital, Athens, Greece
Am J Gastroenterol 104:219-27. 2009..However, the role of bowel preparation is controversial. Therefore, the aim of this study was to explore the role of bowel preparation and in particular its consequences on diagnostic yield in a meta-analysis of all relevant studies...
Coincidental malabsorption of lactose, fructose, and sorbitol ingested at low doses is not common in normal adultsS D Ladas
Second Department of Internal Medicine, Athens University, Evangelismos Hospital, Greece
Dig Dis Sci 45:2357-62. 2000..In conclusion, the frequency of coincidental malabsorption of lactose, fructose, and sorbitol and intolerance to these sugars is not common, when normal adults ingest them at low doses...
Epithelial cell turnover, p53 and bcl-2 protein expression during oncogenesis of early and advanced gastric cancer in a Western populationK Triantafyllou
Hepatogastroenterology Unit, 2nd Department of Internal Medicine, Attikon University General Hospital, Medical School, Athens University, 1 Rimini Street, 12462 Haidari, Athens, Greece
Dig Liver Dis 40:39-45. 2008..To investigate epithelial cell turnover alterations, and p53, bcl-2 protein expression during development of early and advanced gastric cancer in a Western population...
Long-term follow-up of endoscopic therapy of anal canal condylomata acuminata with podophyllotoxinC Tzathas
First Department of Gastroenterology, Evangelismos Hospital, Athens University, 23 Sissini Street, 115 28 Athens, Greece
J Eur Acad Dermatol Venereol 21:364-7. 2007..Condylomata acuminata of the anal canal, a common sexually transmitted disease, are difficult-to-treat lesions with a high recurrence rate after initial successful treatment...
Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitusK Triantafyllou
Hepato Gastroenterology Unit, 2nd Department of Internal Medicine, Medical School, Athens University, Attikon University General Hospital, 124 62 Haidari, Athens, Greece
Dig Liver Dis 39:575-80. 2007..Small intestine video-capsule endoscopy examination in patients with diabetes mellitus may be incomplete due to delayed gastric emptying...
Hospitalization rates for cholelithiasis and acute cholecystitis doubled for the aged population in Greece over the past 30 yearsAngelos A Papadopoulos
Gastroenterology Unit, 2nd Department of Internal Medicine, Medical School, Athens University, Attikon University General Hospital, Athens, Greece
Scand J Gastroenterol 41:1330-5. 2006..CONCLUSIONS: Hospitalization rates for cholelithiasis and/or acute cholecystitis increased by 45%, and doubled for elderly patients, while the case fatality rate of the disease halved in Greece over the past 30 years...
Systematic review: Coca-Cola can effectively dissolve gastric phytobezoars as a first-line treatmentS D Ladas
Gastroenterology Division, First Department of Medicine Propaedeutic, Medical School, Athens University, Laikon Hospital, Athens, Greece
Aliment Pharmacol Ther 37:169-73. 2013..Gastric phytobezoars represent the most common bezoars in patients with poor gastric motility. A variety of dissolution therapies and endoscopic fragmentation techniques have been evaluated as conservative treatment so as to avoid surgery...
Keratinocyte growth factor is effective in the prevention of intestinal mucositis in patients with hematological malignancies treated with high-dose chemotherapy and autologous hematopoietic SCT: a video-capsule endoscopy studyP Tsirigotis
Haematology Unit, Second Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, University of Athens, Athens, Greece
Bone Marrow Transplant 42:337-43. 2008..019). KGF is effective in the prevention of intestinal mucositis in patients undergoing auto-SCT. Patients with severe intestinal mucositis run a higher risk to develop infections...
Serotonin transporter and G protein beta 3 subunit gene polymorphisms in Greeks with irritable bowel syndromeT Markoutsaki
2nd Department of Gastroenterology, Evangelismos General Hospital, Athens, Greece
Dig Dis Sci 56:3276-80. 2011..Association studies of SERT and GNB3 polymorphisms and IBS have shown diverse results among different populations, which might be due to subject composition differences...
Effect of Helicobacter pylori eradication and antisecretory maintenance therapy on peptic ulcer recurrence in cirrhotic patients: a prospective, cohort 2-year follow-up studyCharalambos Tzathas
1st Department of Gastroenterology, Evangelismos Hospital, Athens, Greece
J Clin Gastroenterol 42:744-9. 2008..The role of Helicobacter pylori eradication to cure peptic ulcer disease in patients with cirrhosis is not clear...
Ethical issues in the management of elderly patients in gastroenterology and digestive endoscopySpiros D Ladas
1st Department of Internal Medicine Propaedeutic, University of Athens, Laiko General Hospital of Athens, Medical School, Athens, Greece
Expert Rev Gastroenterol Hepatol 1:257-63. 2007....
A meta-analysis evaluating the accuracy of colon capsule endoscopy in detecting colon polypsTheodore Rokkas
Gastroenterology Clinic, Henry Dunant Hospital, Athens, Greece
Gastrointest Endosc 71:792-8. 2010..Colon capsule endoscopy (CCE) is a new, noninvasive method for examining the entire colon. The reported yield of CCE in detecting colorectal polyps has shown variable results...
Effect of three bowel preparations on video-capsule endoscopy gastric and small-bowel transit time and completeness of the examinationChryssostomos Kalantzis
Department of Gastroenterology, NIMTS Hospital, Athens, Greece
Scand J Gastroenterol 42:1120-6. 2007..The aim of this study was to investigate the effect of different bowel preparations on video capsule endoscopy gastric- (GTT) and small-bowel transit time (SBTT) and the rate of caecal visualization...
A glass of water immediately increases gastric pH in healthy subjectsGeorge Karamanolis
Hepatogastroenteroly Unit, 2nd Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Athens University, Athens, Greece
Dig Dis Sci 53:3128-32. 2008..Onset of action of antisecretory agents is of pivotal importance for patients with gastroesophageal reflux disease (GERD) treated "on-demand."..
Sedation practices for gastrointestinal endoscopy in Europe, North America, Asia, Africa and AustraliaSpiros D Ladas
Hepatogastroenterology Division, 1st Department of Internal Medicine Propaedeutic, Laiko General Hospital of Athens, Medical School, Athens University, Athens, Greece
Digestion 82:74-6. 2010..Our data indicate that the use of sedation for diagnostic gastrointestinal endoscopy is high in North America and Australia, but varies considerably among countries in Europe, Asia and Africa...
Effect of sleep on excessive belching: a 24-hour impedance-pH studyGeorge Karamanolis
Hepatogastroenterology Unit, 2nd Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Athens University, Athens, Greece
J Clin Gastroenterol 44:332-4. 2010..The aim of our study was to investigate the incidence and pattern of belching during a 24-hour period...
European Society of Gastrointestinal Endoscopy (ESGE) Guidelines: flexible enteroscopy for diagnosis and treatment of small-bowel diseasesJ Pohl
Department of Internal Medicine II, Dr Horst Schmidt Kliniken, Wiesbaden, Germany
Endoscopy 40:609-18. 2008
Evaluation of a conventional ELISA (Novitec) and a near patient immunochromatographic test (Stick H. pyl) for Helicobacter pylori antigen detection in stoolIoannis Kyrlagkitsis
Gastroenterology Department, Tzanio Hospital, Pireaeus, Greece
Hepatogastroenterology 54:799-802. 2007..pylori) antigen in stool by conventional ELISA is a reliable non-invasive method for the diagnosis of H. pylori infection in untreated patients. Recently, rapid in-office stool tests have been developed for the same purpose...
Cell turnover of serrated adenomasSpiros D Ladas
Gastroenterology Unit, Second Department of Internal Medicine, Athens University, Attikon University Hospital, Athens, Greece
J Pathol 206:62-7. 2005....
Gastric mucosa epithelial cell kinetics are differentiated by anatomic site and Helicobacter pylori infectionPanagiota Kitsanta
Histopathology Department, Sheffield Teaching Hospitals, Sheffield, United Kingdom
Dig Dis Sci 50:1087-91. 2005..pylori gastritis compared with normal controls. Our data suggest that gastric mucosa epithelial cell kinetics is differentiated by the anatomic site and H. pylori infection...
Sildenafil (viagra) is a risk factor for acute variceal bleedingCharalabos Tzathas
Am J Gastroenterol 97:1856. 2002
Effects of ageing on small bowel video-capsule endoscopy examinationAngelos A Papadopoulos
Hepatogastroenterology Unit, 2nd Department of Internal Medicine Propaedeutic, Medical School, Athens University, Attikon University General Hospital, Athens, Greece
Am J Gastroenterol 103:2474-80. 2008..The effects of ageing on small bowel video-capsule endoscopy (VCE) studies have not been studied prospectively yet...
Professional, legal and ethical challenges in gastroenterology. EditorialSpiros D Ladas
Dig Dis 26:5-6. 2008
Molecular analysis of B-cell clonality in Helicobacter pylori gastritisSotirios D Georgopoulos
Gastroenterology Unit, Evangelismos General Hospital, Athens University, Medical School, Greece
Dig Dis Sci 50:1616-20. 2005..We conclude that certain H. pylori positive gastritis patients show PCR-detectable monoclonality, which is independent of the W-I grade of gastritis and cannot be taken as evidence of an existing neoplastic lesion...
Informed consent: still far from ideal?Spiros D Ladas
Digestion 73:187-8. 2006
Hypergastrinemia is associated with increased risk of distal colon adenomasSotirios D Georgopoulos
Gastroenterology Unit, Evangelismos Hospital, Medical School, University of Athens, Athens, Greece
Digestion 74:42-6. 2006..There was a significant association of hypergastrinemia and distal distribution of adenomas (p < 0.002). CONCLUSIONS: Our study shows that hypergastrinemia is a risk factor for CAs, especially of the distal colon...
