Antonis Kattamis

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint Combined therapy with desferrioxamine and deferiprone in thalassemic patients: effect on urinary iron excretion
    Antonis Kattamis
    Haematologica 88:1423-5. 2003
  2. ncbi request reprint The effects of erythropoetic activity and iron burden on hepcidin expression in patients with thalassemia major
    Antonis Kattamis
    First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, Athens 11527, Greece
    Haematologica 91:809-12. 2006
  3. ncbi request reprint Clinical response and adverse events in young patients with sickle cell disease treated with hydroxyurea
    Antonis Kattamis
    First Department of Pediatrics, University of Athens School of Medicine, Athens, Greece
    Pediatr Hematol Oncol 21:335-42. 2004
  4. ncbi request reprint Combined therapy with deferoxamine and deferiprone
    Antonis Kattamis
    First Department of Pediatrics, University of Athens, Medical School, Aghia Sophia Children s Hospital, Thivon and Levadias, Goudi 115 27, Greece
    Ann N Y Acad Sci 1054:175-82. 2005
  5. ncbi request reprint Iron chelation treatment with combined therapy with deferiprone and deferioxamine: a 12-month trial
    Antonis Kattamis
    First Department of Pediatrics, University of Athens, Medical School, Aghia Sophia Children s Hospital, Thivon and Levadias, Goudi 11527, Greece
    Blood Cells Mol Dis 36:21-5. 2006
  6. doi request reprint Impact of magnetic resonance imaging on cardiac mortality in thalassemia major
    Giorgos Chouliaras
    Thalassaemia Unit, 1st Dept of Paediatrics, University of Athens, Aghia Sophia Children s Hospital, Athens, Greece
    J Magn Reson Imaging 34:56-9. 2011
  7. doi request reprint Adhesion molecules and high-sensitivity C-reactive protein levels in patients with sickle cell beta-thalassaemia
    Ino Kanavaki
    Department of Clinical Biochemistry, Aghia Sophia Children s Hospital, Athens, Greece
    Eur J Clin Invest 42:27-33. 2012
  8. doi request reprint Cardiac magnetic resonance in transfusion dependent thalassaemia: assessment of iron load and relationship to left ventricular ejection fraction
    Giorgos L Chouliaras
    Thalassaemia Unit, First Department of Paediatrics, University of Athens, Aghia Sophia Children s Hospital, Athens, Greece
    Br J Haematol 151:397-401. 2010
  9. doi request reprint Cystatin C levels in patients with beta-thalassemia during deferasirox treatment
    Ioannis Papassotiriou
    Department of Clinical Biochemistry, Aghia Sophia Children s Hospital, Athens, Greece
    Blood Cells Mol Dis 44:152-5. 2010
  10. ncbi request reprint R2 relaxometry with MRI for the quantification of tissue iron overload in beta-thalassemic patients
    Efthymia Alexopoulou
    Second Department of Radiology, National and Kapodistrian University of Athens, Athens, Greece
    J Magn Reson Imaging 23:163-70. 2006

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Combined therapy with desferrioxamine and deferiprone in thalassemic patients: effect on urinary iron excretion
    Antonis Kattamis
    Haematologica 88:1423-5. 2003
  2. ncbi request reprint The effects of erythropoetic activity and iron burden on hepcidin expression in patients with thalassemia major
    Antonis Kattamis
    First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, Athens 11527, Greece
    Haematologica 91:809-12. 2006
    ..We conclude that hepcidin expression is regulated mainly by increased erythropoietic activity rather than by iron load and that hepcidin plays a central regulatory role in iron circulation and iron toxicity in patients with thalassemia...
  3. ncbi request reprint Clinical response and adverse events in young patients with sickle cell disease treated with hydroxyurea
    Antonis Kattamis
    First Department of Pediatrics, University of Athens School of Medicine, Athens, Greece
    Pediatr Hematol Oncol 21:335-42. 2004
    ..HU seems to be effective in a high proportion of young patients with sickle cell disease and in particular with S/beta(thal), but cannot eliminate occurrence of serious adverse events...
  4. ncbi request reprint Combined therapy with deferoxamine and deferiprone
    Antonis Kattamis
    First Department of Pediatrics, University of Athens, Medical School, Aghia Sophia Children s Hospital, Thivon and Levadias, Goudi 115 27, Greece
    Ann N Y Acad Sci 1054:175-82. 2005
    ..Combining the available iron chelators offers many therapeutic options that can be tailored to each patient individually. It is an exciting advance in treating hemosiderosis in thalassemic patients...
  5. ncbi request reprint Iron chelation treatment with combined therapy with deferiprone and deferioxamine: a 12-month trial
    Antonis Kattamis
    First Department of Pediatrics, University of Athens, Medical School, Aghia Sophia Children s Hospital, Thivon and Levadias, Goudi 11527, Greece
    Blood Cells Mol Dis 36:21-5. 2006
    ..Prolonged use of combined therapy with DFP and DFO is effective in decreasing iron load and improving cardiac function. Its possible association with higher incidence of agranulocytosis emphasizes the need for close monitoring...
  6. doi request reprint Impact of magnetic resonance imaging on cardiac mortality in thalassemia major
    Giorgos Chouliaras
    Thalassaemia Unit, 1st Dept of Paediatrics, University of Athens, Aghia Sophia Children s Hospital, Athens, Greece
    J Magn Reson Imaging 34:56-9. 2011
    ..To evaluate whether the introduction of magnetic resonance imaging (MRI) in the management of thalassemia major (TM) patients has affected the risk of cardiac death...
  7. doi request reprint Adhesion molecules and high-sensitivity C-reactive protein levels in patients with sickle cell beta-thalassaemia
    Ino Kanavaki
    Department of Clinical Biochemistry, Aghia Sophia Children s Hospital, Athens, Greece
    Eur J Clin Invest 42:27-33. 2012
    ..Chronic inflammation also plays an important role in the pathophysiology of SCD. We aimed to investigate endothelial activation in Caucasian Greek patients with SCD by means of measuring adhesion molecules and markers of inflammation...
  8. doi request reprint Cardiac magnetic resonance in transfusion dependent thalassaemia: assessment of iron load and relationship to left ventricular ejection fraction
    Giorgos L Chouliaras
    Thalassaemia Unit, First Department of Paediatrics, University of Athens, Aghia Sophia Children s Hospital, Athens, Greece
    Br J Haematol 151:397-401. 2010
    ..Patients with cardiac T2*≤8 ms require careful and intensive management. This risk decreases with increasing values of T2* but even in mildly loaded patients the probability of impaired LVEF is not negligible...
  9. doi request reprint Cystatin C levels in patients with beta-thalassemia during deferasirox treatment
    Ioannis Papassotiriou
    Department of Clinical Biochemistry, Aghia Sophia Children s Hospital, Athens, Greece
    Blood Cells Mol Dis 44:152-5. 2010
    ..However hemodynamic signals such as LVEF alterations and iron mobilization do appear to affect changes in cystatin C concentration...
  10. ncbi request reprint R2 relaxometry with MRI for the quantification of tissue iron overload in beta-thalassemic patients
    Efthymia Alexopoulou
    Second Department of Radiology, National and Kapodistrian University of Athens, Athens, Greece
    J Magn Reson Imaging 23:163-70. 2006
    ..To evaluate the usefulness of a time-efficient MRI method for the quantitative determination of tissue iron in the liver and heart of beta-thalassemic patients using spin-spin relaxation rate, R2, measurements...
  11. doi request reprint Hb Souli, a 6 bp in-frame deletion on the HBA2 gene (HBA2: c.[41-46delCCTGGG]) leads to α-thalassemia intermedia, when in trans to a single α-globin gene deletion
    Antonis Kattamis
    First Department of Pediatrics, Athens University Medical School, Athens, Greece
    Hemoglobin 39:55-7. 2015
    ..41-46delCCTGGG]) is, to the best of our knowledge, the first variant to be reported where both amino acid residues, α13Ala and α14Trp, are deleted, leading to unstable and rapidly degraded α-globin chains...
  12. ncbi request reprint A national registry of haemoglobinopathies in Greece: deducted demographics, trends in mortality and affected births
    Ersi Voskaridou
    Thalassaemia Center, Laikon General Hospital, 16 Sevastoupoleos Street, GR 11526, Athens, Greece
    Ann Hematol 91:1451-8. 2012
    ....
  13. doi request reprint Clinical phenotype and genetic analysis of RPS19, RPL5, and RPL11 genes in Greek patients with Diamond Blackfan Anemia
    Polyxeni Delaporta
    First Department of Pediatrics, University of Athens, Greece
    Pediatr Blood Cancer 61:2249-55. 2014
    ..Here, we present our findings from the study of 17 patients recorded in the Greek DBA registry...
  14. doi request reprint Soluble endothelial adhesion molecules and inflammation markers in patients with beta-thalassemia intermedia
    Ino Kanavaki
    Department of Clinical Biochemistry, Aghia Sophia Children s Hospital, 115 27 Athens, Greece
    Blood Cells Mol Dis 43:230-4. 2009
    ..Furthermore, these findings are of particular importance in patients who can otherwise be characterized by a subtle clinical phenotype and may have an important role in their clinical care...
  15. doi request reprint Survival in a large cohort of Greek patients with transfusion-dependent beta thalassaemia and mortality ratios compared to the general population
    Vassilis Ladis
    Thalassaemia Unit, 1st Department of Paediatrics, University of Athens, Aghia Sophia Children s Hospital, Athens, Greece
    Eur J Haematol 86:332-8. 2011
    ..With transfusions and chelation therapy, the prognosis for transfusion-dependent beta thalassaemia has changed from being fatal in early childhood to a chronic disorder with prolonged survival...
  16. doi request reprint Successful management of a small infant with Kasabach-Merritt phenomenon using vincristine: a case report
    Marina Economou
    a1st Pediatric Department of Aristotle University of Thessaloniki, Hippokration General Hospital bNeonatal Care Unit, Hippokration General Hospital, Thessaloniki c1st Pediatric Department of University of Athens, Agia Sophia Hospital, Athens, Greece
    Blood Coagul Fibrinolysis 25:777-9. 2014
    ....
  17. ncbi request reprint A prospective randomized controlled trial on the safety and efficacy of alternating deferoxamine and deferiprone in the treatment of iron overload in patients with thalassemia
    Renzo Galanello
    Department of Biomedical Science and Biotechnology, University of Cagliari, Ospedale Microcitemico, Italy
    Haematologica 91:1241-3. 2006
    ..There was no significant difference in the proportion of patients with adverse events in the two therapy groups although the nature of the adverse events differed according to the chelation regimen...
  18. ncbi request reprint A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia
    Maria Domenica Cappellini
    Fondazione Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena IRCCS, Universita di Milano, Via F Sforza 35, 20122 Milan, Italy
    Blood 107:3455-62. 2006
    ..No agranulocytosis, arthropathy, or growth failure was associated with deferasirox administration. Deferasirox is a promising once-daily oral therapy for the treatment of transfusional iron overload...
  19. ncbi request reprint Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran
    Ali Taher
    Internal Medicine, American University of Beirut, Beirut, Lebanon
    Thromb Haemost 96:488-91. 2006
    ..Due to the increased risk of thromboembolic events, the rationale for splenectomy should perhaps be re-assessed and the role of transfusion therapy for the prophylaxis of thrombosis, among other complications, be evaluated prospectively...
  20. ncbi request reprint Sustained response to interferon alpha-2a in thalassemic patients with chronic hepatitis C. A prospective 8-year follow-up study
    Vassiliki Syriopoulou
    Haematologica 90:129-31. 2005
    ..Interferon induced sustained virologic and biochemical response in 45% of participants and histologic improvement in 50% of patients who had paired liver biopsies. Splenectomy was the only independent predictor of an unfavorable outcome...
  21. ncbi request reprint Treatment of thalassemia with hydroxyurea: an indispensable alternative therapy
    Antonis Kattamis
    J Pediatr Hematol Oncol 29:729-30. 2007