Georgios M Hadjigeorgiou

Summary

Affiliation: University of Thessaly
Country: Greece

Publications

  1. pmc Pesticide exposure and lymphohaematopoietic cancers: a case-control study in an agricultural region (Larissa, Thessaly, Greece)
    Maria Kokouva
    Department of Hygiene and Epidemiology, Medical Faculty, University of Thessaly, Larissa, Greece
    BMC Public Health 11:5. 2011
  2. ncbi request reprint Low RLS prevalence and awareness in central Greece: an epidemiological survey
    G M Hadjigeorgiou
    Department of Neurology, Medical School of Larissa, University of Thessaly, Larissa, Greece
    Eur J Neurol 14:1275-80. 2007
  3. ncbi request reprint Paraoxonase 1 gene polymorphisms in patients with osteonecrosis of the femoral head with and without cerebral white matter lesions
    Georgios M Hadjigeorgiou
    Neurogenetics Unit, Department of Neurology, School of Medicine, University of Thessaly, Larissa 41222, Greece
    J Orthop Res 25:1087-93. 2007
  4. ncbi request reprint Increased frequency of white matter lesions in patients with osteonecrosis (WMLeOn) of the femoral head
    Georgios M Hadjigeorgiou
    Department of Neurology, Medical School, Larissa University Hospital, University of Thessaly, Larissa 41222, Greece
    Eur J Radiol 50:278-84. 2004
  5. ncbi request reprint Genetic association studies in osteonecrosis of the femoral head: mini review of the literature
    Georgios Hadjigeorgiou
    Department of Neurology, Medical School, Larissa University Hospital, University of Thessaly, 22 Papakyriazi Street, Larissa 41222, Greece
    Skeletal Radiol 37:1-7. 2008
  6. ncbi request reprint IL-1RN and IL-1B gene polymorphisms and cerebral hemorrhagic events after traumatic brain injury
    G M Hadjigeorgiou
    Department of Neurology, University Hospital of Larissa, Medical School, University of Thessaly, Larissa 41222, Greece
    Neurology 65:1077-82. 2005
  7. ncbi request reprint Association of alpha-synuclein Rep1 polymorphism and Parkinson's disease: influence of Rep1 on age at onset
    Georgios M Hadjigeorgiou
    Neurogenetics Unit, Department of Neurology, Medical School, University of Thessaly, Larissa, Greece
    Mov Disord 21:534-9. 2006
  8. pmc Periodic limb movements in sleep contribute to further cardiac structure abnormalities in hemodialysis patients with restless legs syndrome
    Christoforos D Giannaki
    Department of Nephrology, School of Medicine, University of Thessaly, Larissa, Greece
    J Clin Sleep Med 9:147-53. 2013
  9. pmc Evidence of increased muscle atrophy and impaired quality of life parameters in patients with uremic restless legs syndrome
    Christoforos D Giannaki
    Department of Nephrology, University of Thessaly, Larissa, Thessaly, Greece
    PLoS ONE 6:e25180. 2011
  10. ncbi request reprint Molecular genetic study of myophosphorylase deficiency (McArdle's disease) in two Yemenite-Jewish families
    Georgios M Hadjigeorgiou
    Department of Neurology, University of Thessaly, Larissa, Greece
    Neuromuscul Disord 12:824-7. 2002

Detail Information

Publications43

  1. pmc Pesticide exposure and lymphohaematopoietic cancers: a case-control study in an agricultural region (Larissa, Thessaly, Greece)
    Maria Kokouva
    Department of Hygiene and Epidemiology, Medical Faculty, University of Thessaly, Larissa, Greece
    BMC Public Health 11:5. 2011
    ..The aim of this study was to investigate the relationships between exposure to pesticides and LHC in an agricultural region of Greece...
  2. ncbi request reprint Low RLS prevalence and awareness in central Greece: an epidemiological survey
    G M Hadjigeorgiou
    Department of Neurology, Medical School of Larissa, University of Thessaly, Larissa, Greece
    Eur J Neurol 14:1275-80. 2007
    ..We provide further evidence for low prevalence of RLS in south-east Europe and a low level of awareness of RLS in our region...
  3. ncbi request reprint Paraoxonase 1 gene polymorphisms in patients with osteonecrosis of the femoral head with and without cerebral white matter lesions
    Georgios M Hadjigeorgiou
    Neurogenetics Unit, Department of Neurology, School of Medicine, University of Thessaly, Larissa 41222, Greece
    J Orthop Res 25:1087-93. 2007
    ..43; 95%CI = 1.04-1.97; p for trend = 0.03). We conclude that individuals with PON1 192QQ genotype may have increased risk for ONFH and WMLeOn...
  4. ncbi request reprint Increased frequency of white matter lesions in patients with osteonecrosis (WMLeOn) of the femoral head
    Georgios M Hadjigeorgiou
    Department of Neurology, Medical School, Larissa University Hospital, University of Thessaly, Larissa 41222, Greece
    Eur J Radiol 50:278-84. 2004
    ..Although, the clinical significance of WMLeON is still unknown, this finding supports, at least, the hypothesis that non-traumatic osteonecrosis is indeed a multisystem disorder rather than a disease of human skeleton...
  5. ncbi request reprint Genetic association studies in osteonecrosis of the femoral head: mini review of the literature
    Georgios Hadjigeorgiou
    Department of Neurology, Medical School, Larissa University Hospital, University of Thessaly, 22 Papakyriazi Street, Larissa 41222, Greece
    Skeletal Radiol 37:1-7. 2008
  6. ncbi request reprint IL-1RN and IL-1B gene polymorphisms and cerebral hemorrhagic events after traumatic brain injury
    G M Hadjigeorgiou
    Department of Neurology, University Hospital of Larissa, Medical School, University of Thessaly, Larissa 41222, Greece
    Neurology 65:1077-82. 2005
    ..To investigate the association of (variable number tandem repeat) interleukin (IL) 1RN and (-511) IL-1B gene polymorphisms with brain hemorrhagic events after traumatic brain injury (TBI)...
  7. ncbi request reprint Association of alpha-synuclein Rep1 polymorphism and Parkinson's disease: influence of Rep1 on age at onset
    Georgios M Hadjigeorgiou
    Neurogenetics Unit, Department of Neurology, Medical School, University of Thessaly, Larissa, Greece
    Mov Disord 21:534-9. 2006
    ..For Rep1 allele 1, there was neither association with risk of PD nor influence on age at onset. This is the first study showing an influence of Rep1 polymorphism on age at onset of PD...
  8. pmc Periodic limb movements in sleep contribute to further cardiac structure abnormalities in hemodialysis patients with restless legs syndrome
    Christoforos D Giannaki
    Department of Nephrology, School of Medicine, University of Thessaly, Larissa, Greece
    J Clin Sleep Med 9:147-53. 2013
    ..The aim of the current study was to investigate the association of PLMS with indices of cardiac morphology and function in HD patients with RLS as a potential pathway by which PLMS could alter cardiovascular risk...
  9. pmc Evidence of increased muscle atrophy and impaired quality of life parameters in patients with uremic restless legs syndrome
    Christoforos D Giannaki
    Department of Nephrology, University of Thessaly, Larissa, Thessaly, Greece
    PLoS ONE 6:e25180. 2011
    ..Increased evidence of muscle atrophy is also observed in the RLS group and possibly can be attributed to the lack of restorative sleep...
  10. ncbi request reprint Molecular genetic study of myophosphorylase deficiency (McArdle's disease) in two Yemenite-Jewish families
    Georgios M Hadjigeorgiou
    Department of Neurology, University of Thessaly, Larissa, Greece
    Neuromuscul Disord 12:824-7. 2002
    ..This first molecular genetic study of McArdle's disease in Yemenite-Jewish patients expands the already remarkable genetic heterogeneity of McArdle's disease and suggests the existence of ethnic or private mutations within this group...
  11. doi request reprint Association between AKT1 gene and Parkinson's disease: a protective haplotype
    Georgia Xiromerisiou
    University of Thessaly, Medical School, Department of Neurology, Neurogenetics Unit, Papakyriazi 22 Street, Larissa 41222, Greece
    Neurosci Lett 436:232-4. 2008
    ..The data presented here suggest the involvement of AKT1 in protection of PD through many possible mechanisms involving different signaling pathways that could be potential therapeutic targets in the future...
  12. doi request reprint Non-pharmacological management of periodic limb movements during hemodialysis session in patients with uremic restless legs syndrome
    Christoforos D Giannaki
    Department of Nephrology, School of Medicine, University of Thessaly, Larissa, Greece
    ASAIO J 56:538-42. 2010
    ..Independent of intensity, a single bout of intradialytic exercise reduces PLM/hHD in hemodialysis patients with RLS. Further research is needed to establish the acute role of exercise in ameliorating the RLS symptoms...
  13. pmc Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma
    Evangelia E Tsironi
    Department of Ophthalmology, School of Medicine, University of Thessaly, Larissa, Greece
    Mol Vis 15:2890-5. 2009
    ..To investigate possible genetic associations of matrix metalloproteinase-1 (MMP1) and MMP3 gene polymorphisms with exfoliation syndrome (XFS) with (XFS/+G) and without (XFS/-G) glaucoma in a cohort of Greek patients...
  14. doi request reprint Angiotensin-converting enzyme tag single nucleotide polymorphisms in patients with intracerebral hemorrhage
    Efthimios Dardiotis
    Department of Neurology, Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Larissa, Greece
    Pharmacogenet Genomics 21:136-41. 2011
    ..The objective of this study was to clarify the influence of the ACE gene region on the risk of ICH by genotyping tag polymorphisms along ACE gene in two independent ethnically different cohorts...
  15. pmc THAP1 mutations and dystonia phenotypes: genotype phenotype correlations
    Georgia Xiromerisiou
    Department of Molecular Neuroscience and Reta Lila Weston Institute, University College London Institute of Neurology, London, London, United Kingdom Department of Neurology, Faculty of Medicine University of Thessaly, Larissa, Greece
    Mov Disord 27:1290-4. 2012
    ..Greater mutation numbers in different populations will be important and mutation-specific functional studies will be essential to identify the pathogenicity of the various THAP1 mutations. © 2012 Movement Disorder Society...
  16. doi request reprint The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides
    Efthimios Dardiotis
    Department of Neurology, Faculty of Medicine, University of Thessaly, Greece
    Toxicology 307:17-23. 2013
    ..These findings confirm the importance of considering pesticide-gene interactions in future studies in order to gain a better understanding of the pathogenic mechanisms of PD...
  17. ncbi request reprint The role of G196A polymorphism in the brain-derived neurotrophic factor gene in the cause of Parkinson's disease: a meta-analysis
    Elias Zintzaras
    Department of Biomathematics, University of Thessaly School of Medicine, Papakyriazi 22, 41222, Larissa, Greece
    J Hum Genet 50:560-6. 2005
    ..The meta-analysis results suggest that the involvement of the BDNF gene in susceptibility to PD merits further exploration with larger and more rigorous population association studies...
  18. ncbi request reprint Absence of linkage to chromosomes 6q and 16p in a Greek population with knee osteoarthritis
    Aspasia Tsezou
    Department of Biology, Laboratory of Cytogenetics and Medical Genetics, Medical School, University of Thessaly, 41 222 Larissa, Greece
    J Orthop Res 24:1900-5. 2006
    ....
  19. ncbi request reprint Association of paraoxonase 1 gene polymorphisms with risk of Parkinson's disease: a meta-analysis
    Elias Zintzaras
    Department of Biomathematics, University of Thessaly School of Medicine, Papakyriazi 22, Larissa 41222, Greece
    J Hum Genet 49:474-81. 2004
    ..Therefore, the pooled results of the meta-analysis supported that there was an association between PON1-55M/L polymorphism and PD and that PON1-192Q/R polymorphism was unlikely to be a major risk factor for susceptibility to PD...
  20. doi request reprint Relationship between the paraoxonase 1 (PON1) M55L and Q192R polymorphisms and lymphohaematopoietic cancers in a Greek agricultural population
    Maria Kokouva
    Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, Larissa, Greece, 22 Papakyriazi Street, Larissa 42222, Greece
    Toxicology 307:12-6. 2013
    ..The results encourage further investigation on the PON1 polymorphisms and their importance on the individual's susceptibility especially when exposure to pesticides occurs...
  21. doi request reprint Absence of aprataxin gene mutations in a Greek cohort with sporadic early onset ataxia and normal GAA triplets in frataxin gene
    C Daiou
    Laboratory of Neurogenetics, Neuroscience Unit, Department of Neurology, Faculty of Medicine, University of Thessalia, Larissa, Greece
    Neurol Sci 31:393-7. 2010
    ..It is still questionable whether the screening for aprataxin mutation in Greek patients' Friedreich ataxia phenotype is of clinical importance; larger, multicenter studies are necessary to clarify this issue...
  22. doi request reprint Genetic association studies in patients with traumatic brain injury
    Efthimios Dardiotis
    Department of Neurology, Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Larissa, Greece
    Neurosurg Focus 28:E9. 2010
    ....
  23. ncbi request reprint Haemodialysis patients with sleep apnoea syndrome experience increased central adiposity and altered muscular composition and functionality
    Giorgos K Sakkas
    Department of Nephrology, School of Medicine, University of Thessaly, Greece
    Nephrol Dial Transplant 23:336-44. 2008
    ..We tested the hypothesis that apneic dialysis patients due to the lack of restorative sleep will have a further reduced functional capacity and further compromised quality of life compared to their non-apneic counterparts...
  24. pmc Perimetric and retinal nerve fiber layer findings in patients with Parkinson's disease
    Evangelia E Tsironi
    Department of Ophthalmology, University Hospital of Larissa, Faculty of Medicine, University of Thessaly, Mezourlo 41222 Larissa, Greece
    BMC Ophthalmol 12:54. 2012
    ....
  25. ncbi request reprint Retroclival epidural hematoma secondary to a longitudinal clivus fracture
    Konstantinos N Paterakis
    Department of Neurosurgery, Larissa University Hospital, Mesourlo, Greece
    Clin Neurol Neurosurg 108:67-72. 2005
    ....
  26. doi request reprint Network analysis of randomized controlled trials in multiple sclerosis
    Elias Zintzaras
    Department of Biomathematics, University of Thessaly School of Medicine, 2 Panepistimiou Str, Larissa, Greece
    Clin Ther 34:857-869.e9. 2012
    ..The optimal treatment of multiple sclerosis (MS) is not yet well-defined...
  27. pmc Cognitive impairment in heart failure
    Efthimios Dardiotis
    Department of Neurology, University of Thessaly, University Hospital of Larissa, P O Box 1400, Larissa, Greece
    Cardiol Res Pract 2012:595821. 2012
    ..Future studies should focus on elucidating the mechanisms that underlie CI in HF and establishing preventive strategies and treatment approaches...
  28. doi request reprint Genetic factors influencing outcome from neurotrauma
    Efthimios Dardiotis
    Department of Neurology, Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Larissa, Greece
    Curr Opin Psychiatry 25:231-8. 2012
    ..The bibliographic databases MEDLINE, EMBASE and PsycINFO were searched to identify relevant studies...
  29. doi request reprint Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus
    Kostas N Fountas
    Department of Neurosurgery, University Hospital of Larissa, University of Thessaly, Larissa, Greece
    Acta Neurochir Suppl 113:129-33. 2012
    ..The purpose of our study was to evaluate the results of endoscopic third ventriculostomy (ETV) in the management of patients with idiopathic normal pressure hydrocephalus (INPH)...
  30. ncbi request reprint A new stop codon mutation (Y52X) in the myophosphorylase gene in a Greek patient with McArdle's disease
    Georgios M Hadjigeorgiou
    Department of Neurology, University of Thessaly, Larissa, Greece
    J Neurol Sci 194:83-6. 2002
    ..Our data further expand the already remarkable genetic heterogeneity of McArdle's disease. The prevalence of the Y52X mutation in Greek patients with McArdle's disease remains to be determined...
  31. doi request reprint Quantitative spectral analysis of vigilance EEG in patients with obstructive sleep apnoea syndrome: EEG mapping in OSAS patients
    Athanasios G Xiromeritis
    Department of Psychiatry, School of Medicine, University of Thessaly, University Hospital of Larissa, GR 411 10, Larissa, Greece
    Sleep Breath 15:121-8. 2011
    ..The aim of the study was to determine electroencephalogram (EEG) alterations related to the severity of OSA in patients with OSAS and the effect of the nasal continuous positive air pressure (nCPAP) treatment...
  32. ncbi request reprint Cervical spinal cord intramedullary teratoma
    Konstantinos N Paterakis
    Department of Neurosurgery, Larissa University Hospital, Mesourlo, Larissa 411 10, Greece
    Clin Neurol Neurosurg 108:514-7. 2006
    ..The purpose of this case report is to describe the highly unusual localization of the intramedullary teratoma associated with other vertebral malformations. A review of the literature is also presented...
  33. ncbi request reprint Primary spinal intradural extramedullary cysticercosis
    Konstantinos N Paterakis
    Department of Neurosurgery, Larissa University Hospital, 411 10 Larissa, Greece
    Surg Neurol 68:309-11; discussion 312. 2007
    ..Spinal cysticercosis represents an uncommon localization of a common parasitic disease and, in most cases, is associated with intracranial involvement. Once confirmed, the entire neuraxis should be evaluated...
  34. doi request reprint Intradialytic aerobic exercise training ameliorates symptoms of restless legs syndrome and improves functional capacity in patients on hemodialysis: a pilot study
    Giorgos K Sakkas
    Department of Nephrology, School of Medicine, University of Thessaly, Greece
    ASAIO J 54:185-90. 2008
    ..03), and sleep quality (p = 0.01). In the Con-group no changes were observed. In conclusion, aerobic exercise training is safe and efficacious in reducing RLS symptoms and improving quality of life in patients with RLS on HD...
  35. ncbi request reprint Re: Lack of association between the IL1A gene (-889) polymorphism and outcome after head injury. Tanriverdi T et al. Surg Neurol 2006;65:7-10; discussion 10
    Efthimios Dardiotis
    Surg Neurol 66:334-5. 2006
  36. ncbi request reprint The human prion gene M129V polymorphism is not associated with idiopathic Parkinson's disease in three distinct populations
    Sonja W Scholz
    Molecular Genetics Unit, National Institute on Aging, National Institutes of Health, Building 35, Room 1A 1012, Bethesda, MD 20892, USA
    Neurosci Lett 395:227-9. 2006
    ..No association between genotypes in codon 129 and IPD was detected in three distinct populations, suggesting that this PRNP polymorphism has no direct influence on the susceptibility to IPD...
  37. pmc Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study
    Alexis Elbaz
    INSERM, Unit 708, Paris, France
    Lancet Neurol 5:917-23. 2006
    ..Small-scale replication studies were largely non-confirmatory, but a meta-analysis that included data from the original study could not exclude all SNP associations, leaving relevance of several markers uncertain...
  38. ncbi request reprint Family-based association study of the restless legs syndrome loci 2 and 3 in a European population
    David Kemlink
    Institute of Human Genetics, GSF National Research Center for Environment and Health, Munich, Germany
    Mov Disord 22:207-12. 2007
    ..0077, respectively). These results represent the first confirmation of these loci in a mixed European population. Variable results observed in families of different ethnic groups further corroborate the genetic complexity of RLS...
  39. ncbi request reprint Genetics of restless legs syndrome (RLS): State-of-the-art and future directions
    Juliane Winkelmann
    Institute of Human Genetics, GSF National Research Center for Environment and Health, Munich, Germany
    Mov Disord 22:S449-58. 2007
    ..One important prerequisite for future successful genetic studies in RLS is the availability of large and thoroughly phenotyped patients and family samples for linkage as well as association studies...
  40. pmc Autoantibodies to alpha-synuclein in inherited Parkinson's disease
    Katerina K Papachroni
    Laboratory of Biological Chemistry, University of Athens Medical School, Athens, Greece
    J Neurochem 101:749-56. 2007
    ..We hypothesise that these AAb could be involved in pathogenesis of the inherited form of PD...
  41. doi request reprint Serum levels of adipokine retinol-binding protein-4 in relation to renal function: response to Ziegelmeier et al
    Vasileios Papavasileiou
    Diabetes Care 31:e23; author reply e24. 2008
  42. ncbi request reprint Clinical trials in restless legs syndrome--recommendations of the European RLS Study Group (EURLSSG)
    Claudia Trenkwalder
    Paracelsus Elena Hospital, Center of Parkinsonism and Movement Disorders, Klinikstr 16, 34128 Kassel, Germany
    Mov Disord 22:S495-504. 2007
    ..The aim of these recommendations is to support research groups or pharmaceutical companies in the design of optimized study protocols...
  43. ncbi request reprint Validation of the Augmentation Severity Rating Scale (ASRS): a multicentric, prospective study with levodopa on restless legs syndrome
    Diego Garcia-Borreguero
    Fundacion Jimenez Diaz, Madrid, Spain
    Sleep Med 8:455-63. 2007
    ..The changes in each dimension are summed to give an ASRS total score...