Konstantinos N Fountoulakis

..The development of treatment guidelines emerged as an important element so as to standardize treatment and to provide clinicians with algorithms, which would be able to carry research findings to the everyday clinical practice...

..Bipolar depression seems to be a more difficult condition to treat than mania. Most patients need complex combination treatment although the published evidence on this type of treatment is limited...

..42, 0.63 and 0.48, respectively). CONCLUSION: The data analysed for the current study support the usefulness of aripiprazole against psychotic symptoms during the acute manic and maintenance phases of bipolar illness...

..The review does not aim to address the issue of a possible etiological connection between previously being the victim of violent acts and later developing a personality disorder...

..The most impressive neurocognitive improvement concerned the clock drawing test, which was in parallel with her improvement in both the positive and negative symptoms of the PANSS...

..The current study aimed to compare the properties of some of the most popular of these scales...

..There is a strong possibility that the presence of a subtle thyroid dysfunction is a negative prognostic factor for depression and may demand specific therapeutic intervention...

..Combination therapy may improve the treatment outcome but it also carries more side-effect burden. Further research is necessary as well as the development of better guidelines and algorithms for the step-by-step rational treatment...

..The results of the present study corroborate the increased prevalence of obesity in schizophrenia. The interpretation of this finding remains unclear...

..Combination therapy may improve treatment outcome but it also carries the burden of more side-effects. Further research as well as the development of better guidelines and algorithms for step-by-step rational treatment are necessary...

..The aim of the current study was to construct a self-report instrument with emphasis on items describing suicide-related behavior itself rather than strongly related clinical features on the basis of a general population study...

..The aim of the present work was to review and meta-analyze the findings of all the available randomized double-blind controlled trials (RCTs) on the efficacy of aripiprazole in the treatment of bipolar disorder...

..The great advantage of this instrument is the fact that it is paper and pencil, easily administered and little time consuming. Further research is necessary to test its usefulness as a neuropsychologic test...

..To our knowledge, his is the first case report in the literature of tardive dyskinesia induced by amisulpride...

..The question that arises is whether this finding is valid or whether these patients (who have higher personality psychopathology and interpersonal rejection sensitivity) tend to over-report life events...

..abstract:..

..Treatment includes the careful combination of lithium, antiepileptics, atypical antipsychotics, and antidepressants, but not all of the agents in these broad categories are effective for the treatment of bipolar disorder...

..It is desirable to keep lithium blood levels as low as feasible with prophylaxis...

..The current article attempts to summarize the current status of our knowledge and practice in the treatment of bipolar depression and suggests future directions...

..abstract:..

..The drug effect is always present and is unrelated to depression severity, while this is not true for placebo...

..Future randomised controlled trials should specifically focus on issues concerning depression and suicidal thoughts in patients with epilepsy...

..Forty-one cases were identified, caused by antipsychotics, antiepileptics, stimulants and other medication. A number of treatment options are reported in the literature but no systematic study of the syndrome has been done yet...

..The aim of our study was to systematically review the literature concerning the efficacy of psychosocial interventions in reducing the risk for attempting or committing suicide...

..This study aimed to search for correlations among Dexamethasone Suppression Test (DST) cortisol levels, thyroid indices, and family history of dementia in patients with depression...

..We provide here a review of currently available data regarding the CC neuroimaging and neuropathological alterations in BD...

..The present article explores the possible existence of a true 'class effect' for agents available for the treatment of bipolar disorder...

..After substitution of sertraline, her depression resolved after 4 weeks and ecchymoses 1.5 months latter. This is an unexplored side-effect with unknown long-term consequences that warrants further study...

..New, randomized prospective trials involving homogeneous cohorts of mixed bipolar patients are needed in order to delineate the appropriate pharmacological treatment of mixed states...

..On the contrary, demented patients even the last few months before the clinical onset of dementia experience low life-events-related stress, possibly because of subclinical impairment which is already present...

..Very short duration interventions don't seem to have even this slight effect...

..The purpose of this paper is to review the most recent literature on personality disorders...

..The above have profound implications in the understanding of late-life depression and to the therapeutic design, especially in the primary care setting...

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..abstract:..

..While the response in the placebo group is due to unstable 'noise' and 'artefacts', the medication effect is reliable, valid and stable...

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..To report a case of an acute dystonic episode in a patient with Tourette's disorder (TD) treated with the partial dopamine agonist aripiprazole...

..The current article is a systematic review concerning the efficacy and safety of aripiprazole in the treatment of bipolar disorder...

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..The two diagnostic groups differed on all 4 factors scores at p-value <0.001...

..The aim of the current preliminary study was to assess the reliability, validity and psychometric properties of the Greek translation of the MDI...

..The IPDE assesses pathological personality and is compatible both with DSM-IV and ICD-10 diagnosis. However it is important to test the reliability and cultural applicability of different IPDE translations...

..The aim of the current study was to test the properties of a scale especially developed for use in epidemiological surveys in low sociocultural populations, and to determine whether this scale can be used in a clinical population...

..The DSM demand that the existence of melancholic features be excluded first and then that diagnosis of atypical features be made was confirmed...

..The present study investigated whether it is possible to predict the medium term response to venlafaxine using biological markers and psychophysiological methods...

..The scale consists of 42 items and permits the calculation of the scores of the Beck Depression Inventory (BDI)-21, the BDI 13, the Melancholia Subscale, the Asthenia Subscale, the Anxiety Subscale and the Mania Subscale..

..Further study is needed to test whether psychophysiological methods, which are noninvasive and easy to perform, are of value in the therapeutic planning and monitoring of responses...