Moses Elisaf

Summary

Affiliation: University of Ioannina
Country: Greece

Publications

  1. ncbi request reprint Hypocholesterolemia
    Elisavet Moutzouri
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Curr Vasc Pharmacol 9:200-12. 2011
  2. ncbi request reprint Aliskiren in patients with diabetes: a systematic review
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Curr Vasc Pharmacol 10:140-6. 2012
  3. ncbi request reprint Recommendations for Severe Hypertriglyceridemia Treatment, are there New Strategies?
    Theodosios D Filippatos
    Department of Internal Medicine, School of Medicine, University of Ioannina, 45 110 Ioannina, Greece
    Curr Vasc Pharmacol 12:598-616. 2014
  4. ncbi request reprint Sodium-glucose co-transporter 2 inhibition in diabetes treatment: current evidence and future perspectives
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, 451 10 Ioannina, Greece
    Curr Pharm Des 20:3647-56. 2014
  5. pmc The effect of combining rosuvastatin with sartans of different peroxisome proliferator receptor-γ activating capacity on plasma 8-isoprostane prostaglandin F2a levels
    Christos V Rizos
    Department of Internal Medicine, School of Medicine, University of Ioannina, Greece
    Arch Med Sci 9:172-6. 2013
  6. pmc Dyslipidemia associated with chronic kidney disease
    Vasilis Tsimihodimos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Open Cardiovasc Med J 5:41-8. 2011
  7. pmc Life-threatening hypophosphataemia in a cirrhotic patient with jaundice
    Elisavet Moutzouri
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Arch Med Sci 7:736-9. 2011
  8. pmc Fenofibrate in primary biliary cirrhosis: a pilot study
    E N Liberopoulos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, 45110, Greece
    Open Cardiovasc Med J 4:120-6. 2010
  9. pmc Effects of eprosartan on serum metabolic parameters in patients with essential hypertension
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Open Cardiovasc Med J 1:22-6. 2007
  10. pmc The relationship of vitamin D with non-traditional risk factors for cardiovascular disease in subjects with metabolic syndrome
    Stefania Makariou
    Department of Child Health, Medical School, University of Ioannina, Greece
    Arch Med Sci 8:437-43. 2012

Collaborators

Detail Information

Publications82

  1. ncbi request reprint Hypocholesterolemia
    Elisavet Moutzouri
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Curr Vasc Pharmacol 9:200-12. 2011
    ..Understanding hypocholesterolemia and the underlying molecular basis is of crucial importance since this may provide new insights in the treatment of hypercholesterolemia and cardiovascular disease...
  2. ncbi request reprint Aliskiren in patients with diabetes: a systematic review
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Curr Vasc Pharmacol 10:140-6. 2012
    ..This is a poorly investigated field with few RCTs and new studies focusing on "hard" outcomes are needed...
  3. ncbi request reprint Recommendations for Severe Hypertriglyceridemia Treatment, are there New Strategies?
    Theodosios D Filippatos
    Department of Internal Medicine, School of Medicine, University of Ioannina, 45 110 Ioannina, Greece
    Curr Vasc Pharmacol 12:598-616. 2014
    ..Clinicians should be vigilant for the recognition and prompt treatment of patients with severe hypertriglyceridemia aimed to avoid the serious complication of pancreatitis and to reduce their cardiovascular risk. ..
  4. ncbi request reprint Sodium-glucose co-transporter 2 inhibition in diabetes treatment: current evidence and future perspectives
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, 451 10 Ioannina, Greece
    Curr Pharm Des 20:3647-56. 2014
    ..Their potency in different populations and with different background therapy, but more importantly their short and long term safety remains to be seen. ..
  5. pmc The effect of combining rosuvastatin with sartans of different peroxisome proliferator receptor-γ activating capacity on plasma 8-isoprostane prostaglandin F2a levels
    Christos V Rizos
    Department of Internal Medicine, School of Medicine, University of Ioannina, Greece
    Arch Med Sci 9:172-6. 2013
    ..Oxidative stress is associated with the development and progression of cardiovascular disease. Plasma 8-isoprostane prostaglandin F2a (8-iso-PGF2a) levels are a reliable marker of oxidative stress...
  6. pmc Dyslipidemia associated with chronic kidney disease
    Vasilis Tsimihodimos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Open Cardiovasc Med J 5:41-8. 2011
    ..In addition, the results of the studies that tested the effects of the hypolipidemic drugs on cardiovascular morbidity and mortality in patients with CKD are reported...
  7. pmc Life-threatening hypophosphataemia in a cirrhotic patient with jaundice
    Elisavet Moutzouri
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Arch Med Sci 7:736-9. 2011
    ..This generalized proximal tubular defect may occasionally be seen in deeply jaundiced patients. Therefore, serum phosphate levels should be closely monitored in these patients...
  8. pmc Fenofibrate in primary biliary cirrhosis: a pilot study
    E N Liberopoulos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, 45110, Greece
    Open Cardiovasc Med J 4:120-6. 2010
    ..Most patients with primary biliary cirrhosis (PBC) are treated with ursodeoxycholic acid (UDCA); however, some do not respond fully. PBC is also associated with dyslipidemia, but a link with vascular risk has not been confirmed...
  9. pmc Effects of eprosartan on serum metabolic parameters in patients with essential hypertension
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Open Cardiovasc Med J 1:22-6. 2007
    ..In conclusion, eprosartan should be mainly considered as an anti-hypertensive agent with neutral effects on most of the metabolic parameters in hypertensive patients...
  10. pmc The relationship of vitamin D with non-traditional risk factors for cardiovascular disease in subjects with metabolic syndrome
    Stefania Makariou
    Department of Child Health, Medical School, University of Ioannina, Greece
    Arch Med Sci 8:437-43. 2012
    ....
  11. ncbi request reprint Combination therapies of DPP4 inhibitors and GLP1 analogues with insulin in type 2 diabetic patients: a systematic review
    Evangelos C Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Curr Vasc Pharmacol 11:992-1000. 2013
    ..The use of dipeptidyl-peptidase 4 (DPP4) inhibitors and glucagon like peptide 1 (GLP1) analogues for the treatment of diabetic mellitus (DM) type 2 is growing. Currently some of these agents have been approved in combination with insulin...
  12. ncbi request reprint Mitochondrial triglyceride transfer protein inhibition: new achievements in the treatment of dyslipidemias
    Michael S Kostapanos
    Department of Internal Medicine, Medical School, University of Ioannina, 451 10 Ioannina, Greece
    Curr Pharm Des 19:3150-60. 2013
    ..Future clinical trials are warranted to assess the efficacy and safety of MTP inhibitors in various clinical states...
  13. doi request reprint Effects of statin monotherapy versus statin plus ezetimibe combination on serum uric acid levels
    Elisavet Moutzouri
    Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece
    J Cardiovasc Pharmacol Ther 18:13-8. 2013
    ..Uric acid is considered a risk factor for cardiovascular disease (CVD). The effect of statins and ezetimibe on serum uric acid levels has not been yet clarified...
  14. ncbi request reprint Effects of sibutramine plus verapamil sustained release/trandolapril combination on blood pressure and metabolic variables in obese hypertensive patients
    E Nakou
    University of Ioannina, Department of Internal Medicine, School of Medicine, 45 110 Ioannina, Greece
    Expert Opin Pharmacother 9:1629-39. 2008
    ....
  15. ncbi request reprint Diagnosis of the metabolic syndrome: which definition should we use?
    Evagelos N Liberopoulos
    Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece
    Hellenic J Cardiol 46:258-62. 2005
  16. ncbi request reprint Do statins beneficially or adversely affect glucose homeostasis?
    Michael S Kostapanos
    Department of Internal Medicine, School of Medicine, University of Ioannina, 45110 Ioannina, Greece
    Curr Vasc Pharmacol 8:612-31. 2010
    ..Comparison trials suggest a potential preferable effect of the hydrophilic statins pravastatin, rosuvastatin and pitavastatin as compared to lipophilic components of the class, including atorvastatin and simvastatin...
  17. doi request reprint Centralized Pan-European survey on the undertreatment of hypercholesterolemia in patients using lipid lowering drugs--the CEPHEUS-Greece survey
    Moses S Elisaf
    Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece
    Angiology 61:465-74. 2010
    ..Hypercholesterolemia is suboptimally managed in Greece, with almost 50% of patients on LLDs not reaching the LDL-C target...
  18. ncbi request reprint Plasma lipoproteins and triacylglycerol are predictors of small, dense LDL particles
    Vasilis Tsimihodimos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110, Ioannina, Greece
    Lipids 42:403-9. 2007
    ....
  19. ncbi request reprint How safe is the use of thiazolidinediones in clinical practice?
    C V Rizos
    Department of Internal Medicine, University of Ioannina, School of Medicine, Ioannina 45110, Greece
    Expert Opin Drug Saf 8:15-32. 2009
    ..The first TZD, troglitazone, was withdrawn from the market owing to serious hepatotoxicity. However, this does not seem to be the case with newer TZDs...
  20. ncbi request reprint The effects of ezetimibe and orlistat, alone or in combination, on high-density lipoprotein (HDL) subclasses and HDL-associated enzyme activities in overweight and obese patients with hyperlipidaemia
    E S Nakou
    University of Ioannina, Medical School, Department of Internal Medicine, 45 110 Ioannina, Greece
    Expert Opin Pharmacother 9:3151-8. 2008
    ..2 mmol/l)]...
  21. ncbi request reprint A tumor lysis-like syndrome during therapy of visceral leishmaniasis
    Evagelos Liberopoulos
    Department of Internal Medicine, University of Ioannina, Ioannina, Greece
    Ann Clin Lab Sci 32:419-21. 2002
    ..Awareness of this condition can lead to prophylactic treatment as well as the early recognition and management of susceptible patients...
  22. ncbi request reprint The hypertriglyceridemic waist phenotype is a predictor of elevated levels of small, dense LDL cholesterol
    Irene F Gazi
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Lipids 41:647-54. 2006
    ..The HTGW phenotype, compared with the MetSyn criteria, can provide an easy and inexpensive tool to monitor patients characterized by an adverse lipid and lipoprotein profile...
  23. pmc Native valve endocarditis due to Micrococcus luteus: a case report and review of the literature
    George Miltiadous
    Hippocrateon Private Hospital, Nicosia, Cyprus
    J Med Case Reports 5:251. 2011
    ..abstract:..
  24. pmc Study rationale and design of OPTIMISE, a randomised controlled trial on the effect of benchmarking on quality of care in type 2 diabetes mellitus
    Frank Nobels
    Endocrinologie, OLV Ziekenhuis, Moorselbaan 164, B 9300 Aalst, Belgium
    Cardiovasc Diabetol 10:82. 2011
    ..To investigate the effect of physician- and patient-specific feedback with benchmarking on the quality of care in adults with type 2 diabetes mellitus (T2DM)...
  25. ncbi request reprint The inhibitory potency of clopidogrel on ADP-induced platelet activation is not attenuated when it is co-administered with atorvastatin (20 mg/day) for 5 weeks in patients with acute coronary syndromes
    John V Mitsios
    Laboratory of Biochemistry, Department of Chemistry, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Platelets 16:287-92. 2005
    ..In conclusion, atorvastatin, even at a dose of 20 mg/day does not affect the antiplatelet efficacy of clopidogrel when co-administered for 5 weeks in ACS patients...
  26. ncbi request reprint Differential effect of hypolipidemic drugs on lipoprotein-associated phospholipase A2
    Vasilios G Saougos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Arterioscler Thromb Vasc Biol 27:2236-43. 2007
    ..We investigated the effect of 3 hypolipidemic drugs that exert their action through different mechanisms on plasma and lipoprotein-associated Lp-PLA2 activity and mass...
  27. ncbi request reprint Hypertriglyceridaemic waist phenotype criteria and prevalent metabolic triad in women
    Irene F Gazi
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Diabetes Metab Res Rev 24:223-30. 2008
    ....
  28. ncbi request reprint Effect of barnidipine on blood pressure and serum metabolic parameters in patients with essential hypertension: a pilot study
    Athanasia Spirou
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    J Cardiovasc Pharmacol Ther 11:256-61. 2006
    ..Barnidipine should be mainly considered as an antihypertensive agent with neutral effects on most of the studied metabolic parameters in hypertensive patients. Any antioxidant effect of barnidipine needs further investigation...
  29. ncbi request reprint Combined treatment with fibrates and small doses of atorvastatin in patients with mixed hyperlipidemia
    George Liamis
    Department of Internal Medicine, University of Ioannina, Greece
    Curr Med Res Opin 18:125-8. 2002
    ..We conclude that the careful administration of small doses of atorvastatin in patients with mixed dyslipidemia receiving fibrates is associated with a significant amelioration of lipid abnormalities...
  30. ncbi request reprint Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-containing lipoproteins
    Vasilis Tsimihodimos
    Department of Internal Medicine, University of Ioannina, 45110 Ioannina, Greece
    J Lipid Res 44:927-34. 2003
    ....
  31. ncbi request reprint Genetic and environmental factors affecting the response to statin therapy in patients with molecularly defined familial hypercholesterolaemia
    George Miltiadous
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Pharmacogenet Genomics 15:219-25. 2005
    ..Specifically, patients with a class V mutation exhibit higher percentage decrease in LDL-C and apoB levels after statin therapy compared to patients sharing class II mutations...
  32. ncbi request reprint Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes
    John V Mitsios
    Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Ioannina, Greece
    Circulation 109:1335-8. 2004
    ..We investigated whether the coadministration of atorvastatin for 5 weeks in patients with acute coronary syndromes (ACS) could affect the antiplatelet potency of clopidogrel...
  33. ncbi request reprint Effect of fenofibrate on serum inflammatory markers in patients with high triglyceride values
    Vasilis Tsimihodimos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    J Cardiovasc Pharmacol Ther 9:27-33. 2004
    ..In this context, a number of inflammatory markers have been studied for their ability to predict future cardiovascular events in asymptomatic individuals or patients with established atherosclerotic disease...
  34. doi request reprint Effect of simvastatin/ezetimibe 10/10 mg versus simvastatin 40 mg on serum vitamin D levels
    Evangelos N Liberopoulos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    J Cardiovasc Pharmacol Ther 18:229-33. 2013
    ..Statins are reported to increase 25(OH)VitD concentration. Animal studies suggest that ezetimibe is a moderate inhibitor of intestinal 25(OH)VitD absorption, but its effect in humans is unknown...
  35. ncbi request reprint The PON1 M55L gene polymorphism is associated with reduced HDL-associated PAF-AH activity
    Anna I Kakafika
    Department of Internal Medicine, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece
    J Lipid Res 44:1919-26. 2003
    ....
  36. ncbi request reprint Disturbances of phosphate metabolism: another feature of metabolic syndrome
    Rigas Kalaitzidis
    Department of Nephrology, Medical School, University of Ioannina, Greece
    Am J Kidney Dis 45:851-8. 2005
    ..The aim of our study is to confirm the presence of hypophosphatemia in patients with metabolic syndrome, as well as investigate mechanisms that may underlie the disturbances in phosphate metabolism in this patient group...
  37. doi request reprint Plasma triglyceride levels and body mass index values are the most important determinants of prebeta-1 HDL concentrations in patients with various types of primary dyslipidemia
    Vasilis Tsimihodimos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Atherosclerosis 208:506-11. 2010
    ..The aim of the present study was the direct comparison of prebeta-1 HDL values in individuals with various types of primary dyslipidemias...
  38. ncbi request reprint Electrolyte disturbances in patients with hyponatremia
    George Liamis
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Intern Med 46:685-90. 2007
    ....
  39. ncbi request reprint Effect of statin treatment on renal function and serum uric acid levels and their relation to vascular events in patients with coronary heart disease and metabolic syndrome: a subgroup analysis of the GREek Atorvastatin and Coronary heart disease Evaluati
    Vasilios G Athyros
    FASA, FRSH, Department of Internal Medicine, Medical School, University of Ioannina, 451 10 Ioannina, Greece
    Nephrol Dial Transplant 22:118-27. 2007
    ..Metabolic syndrome (MetS) is associated with increased risk for both vascular and chronic kidney disease. Whether statins ameliorate these risks is not established...
  40. ncbi request reprint Effect of ciprofibrate on lipoproteins, fibrinogen, renal function, and hepatic enzymes
    Evangelos Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, Greece
    J Cardiovasc Pharmacol Ther 7:219-26. 2002
    ..The aim of this study is to answer this question...
  41. ncbi request reprint Gene polymorphisms affecting HDL-cholesterol levels in the normolipidemic population
    George Miltiadous
    Department of Internal Medicine, Medical School, University of Ioannina, GR 451 10 Ioannina, Greece
    Nutr Metab Cardiovasc Dis 15:219-24. 2005
    ....
  42. ncbi request reprint Effect of ezetimibe monotherapy on the concentration of lipoprotein subfractions in patients with primary dyslipidaemia
    Mihalis Kalogirou
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Curr Med Res Opin 23:1169-76. 2007
    ..Therefore, we evaluated the effect of ezetimibe (a selective cholesterol transport inhibitor) on the concentrations of lipoprotein subfractions in patients with primary dyslipidaemia...
  43. doi request reprint Effect of hypolipidemic treatment on emerging risk factors in mixed dyslipidemia: a randomized pilot trial
    Anastazia Kei
    Department of Internal Medicine, University of Ioannina Medical School, Ioannina, Greece
    Eur J Clin Invest 43:698-707. 2013
    ..The effects of different hypolipidemic treatment strategies on emerging atherosclerosis risk factors remain unknown...
  44. ncbi request reprint Altered distribution of platelet-activating factor- acetylhydrolase activity between LDL and HDL as a function of the severity of hypercholesterolemia
    Vasilis Tsimihodimos
    Department of Internal Medicine, University of Ioannina, 45110 Ioannina, Greece
    J Lipid Res 43:256-63. 2002
    ..Thus, the ratio of HDL-associated PAF-AH-total plasma enzyme activity may be useful as a potential marker of atherogenicity in subjects with primary hypercholesterolemia...
  45. doi request reprint Regression of Achilles tendon thickness after statin treatment in patients with familial hypercholesterolemia: an ultrasonographic study
    Sofia G Tsouli
    Department of Internal Medicine, University of Ioannina, Ioannina, Greece
    Atherosclerosis 205:151-5. 2009
    ..The aim of this study was to evaluate clinical and ultrasonographic changes of ATX in patients with FH under statin treatment...
  46. ncbi request reprint Statins and renal function
    Moses Elisaf
    Department of Internal Medicine, Medical School, University of Ioannina, Greece
    Angiology 53:493-502. 2002
    ..Which is the statin of choice? This question is relevant because impaired renal function can interfere with statin pharmacokinetics. Furthermore, other drugs administered to these patients may cause serious interactions with statins...
  47. pmc LDL cholesterol estimation in patients with the metabolic syndrome
    Irene Gazi
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Lipids Health Dis 5:8. 2006
    ..The aim of the present study was to evaluate various LDL cholesterol calculation formulas as well as LDL cholesterol levels provided by the Lipoprint LDL System (LDL-L) in patients with the metabolic syndrome (MetSyn)...
  48. ncbi request reprint The effects of the addition of micronised fenofibrate on uric acid metabolism in patients receiving indapamide
    Apostolos Achimastos
    Department of Internal Medicine, Medical School, University of Athens, Greece
    Curr Med Res Opin 18:59-63. 2002
    ..In contrast, micronised fenofibrate can significantly decrease serum uric acid levels. However, there are no data on the effect of combination therapy of indapamide with micronised fenofibrate on uric acid metabolism...
  49. ncbi request reprint The role of renin-angiotensin system inhibition in the treatment of hypertension in metabolic syndrome: are all the angiotensin receptor blockers equal?
    Asterios Karagiannis
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Expert Opin Ther Targets 11:191-205. 2007
    ..There are differences among ARBs. Among them is the uricosuric effect of losartan. Furthermore, telmisartan may function as a partial agonist of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma)...
  50. ncbi request reprint Compositional lipoprotein changes and low-density lipoprotein susceptibility to oxidation in chronic renal failure patients with heavy proteinuria
    Sonia Athena Karabina
    Department of Chemistry, Laboratory of Biochemistry, Medical School, University of Ioannina, Ioannina, Greece
    Nephron Clin Pract 95:c77-83. 2003
    ..In this report, we focused on lipoprotein changes observed in uremic patients with proteinuria as well as on the susceptibility of low-density lipoprotein (LDL) of these patients to oxidative modification in vitro...
  51. doi request reprint Effects of rimonabant, as monotherapy and in combination with fenofibrate or ezetimibe, on plasma adipokine levels: a pilot study
    Matilda Florentin
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Angiology 61:365-71. 2010
    ..047). Treatment with rimonabant may improve adipokine levels in overweight/obese patients with dyslipidemia. The addition of fenofibrate or ezetimibe may reinforce this effect...
  52. ncbi request reprint Lipoprotein-associated phospholipase A2 activity is a marker of small, dense LDL particles in human plasma
    Irene Gazi
    Department of Internal Medicine, Medical School, University of Ioannina, Greece
    Clin Chem 51:2264-73. 2005
    ..We investigated whether Lp-PLA(2) could be a marker of sdLDL in human plasma...
  53. doi request reprint Efficacy and safety of ezetimibe plus orlistat or rimonabant in statin-intolerant nondiabetic overweight/obese patients with dyslipidemia
    Matilda Florentin
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    J Cardiovasc Pharmacol Ther 14:274-82. 2009
    ..To compare the effects of ezetimibe plus orlistat or rimonabant on anthropometric and lipid parameters in nondiabetic statin-intolerant overweight/obese patients with dyslipidemia...
  54. doi request reprint Ezetimibe treatment lowers indicators of oxidative stress in hypercholesterolemic subjects with high oxidative stress
    Michael S Kostapanos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Lipids 46:341-8. 2011
    ..Ezetimibe may decrease markers of oxidative stress in hypercholesterolemic subjects. This benefit may be more profound among patients who exhibit 'high oxidative stress' at baseline...
  55. doi request reprint Effect of rosuvastatin monotherapy and in combination with fenofibrate or omega-3 fatty acids on serum vitamin D levels
    Stefania E Makariou
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    J Cardiovasc Pharmacol Ther 17:382-6. 2012
    ..Low levels of 25(OH) vitamin D [25(OH)VitD] have been recognized as a new cardiovascular disease (CVD) risk factor. Statins seem to increase 25(OH)VitD concentration...
  56. ncbi request reprint Effect of atorvastatin on the concentration, relative distribution, and chemical composition of lipoprotein subfractions in patients with dyslipidemias of type IIA and IIB
    Vasilis Tsimihodimos
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    J Cardiovasc Pharmacol 42:304-10. 2003
    ..Thus, the percentage mass distribution of LDL particles remained unaffected. These results suggest that the effect of atorvastatin on LDL subfractions is affected by the underlying genetic defect...
  57. doi request reprint Causes and mechanisms of acid-base and electrolyte abnormalities in cancer patients
    George Miltiadous
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Eur J Intern Med 19:1-7. 2008
    ..This article briefly reviews the causes and the pathophysiology of acid-base and electrolyte abnormalities observed in cancer patients...
  58. doi request reprint Blood pressure levels constitute the most important determinant of the metabolic syndrome in a Mediterranean population: a discrimination analysis
    Theodoros Chimonas
    Department of Internal Medicine, Medical School, University of Ioannina, Greece
    Metab Syndr Relat Disord 8:523-9. 2010
    ..The aim of the study was to evaluate the relative importance of the determinants of the metabolic syndrome in a sample with metabolic syndrome from the Greek population...
  59. doi request reprint Lipid-modulating treatments for mixed dyslipidemia increase HDL-associated phospholipase A2 activity with differential effects on HDL subfractions
    Anastazia Kei
    Department of Internal Medicine, University of Ioannina Medical School, 45 110, Ioannina, Greece
    Lipids 48:957-65. 2013
    ..Add-on-ER-NA/LRPT was associated with the most pronounced increase in HDL-Lp-PLA2 activity. ..
  60. ncbi request reprint Aminoglycoside-induced reversible tubular dysfunction
    George Alexandridis
    Department of Internal Medicine, University of Ioannina Medical School, Ioannina, Greece
    Pharmacology 67:118-20. 2003
    ....
  61. ncbi request reprint Effects of fibrates on serum metabolic parameters
    Moses Elisaf
    Department of Internal Medicine, Medical School, University of Ioannina, Greece
    Curr Med Res Opin 18:269-76. 2002
    ..The fibrates are generally well-tolerated drugs with few side-effects. The most important side-effect is myositis, which is observed in patients with impaired renal function or when statins are given concomitantly...
  62. ncbi request reprint The combination of nebivolol plus pravastatin is associated with a more beneficial metabolic profile compared to that of atenolol plus pravastatin in hypertensive patients with dyslipidemia: a pilot study
    Evangelos Rizos
    Department of Internal Medicine, Medical School, University of Ioannina, Greece
    J Cardiovasc Pharmacol Ther 8:127-34. 2003
    ..Finally, the addition of pravastatin could further correct the well-established predictors of cardiovascular events...
  63. ncbi request reprint Analysis of the composition of plasma lipoproteins in patients with extensive coronary heart disease using 1H NMR spectroscopy
    Athanasios Papathanasiou
    Department of Cardiology, School of Medicine, University of Ioannina, Greece
    Hellenic J Cardiol 49:72-8. 2008
    ..In the present study 1H NMR spectroscopy was used to analyse the lipid composition of HDL and nonHDL lipoproteins in patients with triple vessel CHD and in patients with normal coronary arteries...
  64. ncbi request reprint Autoantibody titers against OxLDL are correlated with Achilles tendon thickness in patients with familial hypercholesterolemia
    Sofia G Tsouli
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    J Lipid Res 47:2208-14. 2006
    ..We conclude that the IgG autoantibody titers against OxLDL(D) but not OxLDL or Lp-PLA(2) may play an important role in the pathogenesis of Achilles tendon xanthomas in FH patients...
  65. ncbi request reprint Concentration and relative distribution of low-density lipoprotein subfractions in patients with metabolic syndrome defined according to the National Cholesterol Education Program criteria
    Irene Gazi
    Department of Internal Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Metabolism 55:885-91. 2006
    ..This increase is directly related to the number of components of metabolic syndrome and is mainly determined by the serum concentrations of triglycerides...
  66. ncbi request reprint Effects of antihypertensive and hypolipidemic drugs on plasma and high-density lipoprotein-associated platelet activating factor-acetylhydrolase activity
    Afroditi P Tambaki
    Laboratory of Biochemistry, Department of Chemistry, Medical School, University of Ioannina, Greece
    J Cardiovasc Pharmacol Ther 9:91-5. 2004
    ..However, the influence of these drugs on the enzyme activity has not been adequately studied...
  67. doi request reprint Pleiotropic effects of ezetimibe: do they really exist?
    Michalis Kalogirou
    Department of Internal Medicine, University of Ioannina, Ioannina, Greece
    Eur J Pharmacol 633:62-70. 2010
    ..This article aims to review the potential pleiotropic effects of the drug mainly on inflammation markers, lipoprotein subfractions and endothelial function...
  68. ncbi request reprint Lipoprotein-associated PAF-acetylhydrolase activity in subjects with the metabolic syndrome
    Evangelos Rizos
    School of Medicine, Department of Internal Medicine, University of Ioannina, Dourouti Campus, 45110 Ioannina, Greece
    Prostaglandins Leukot Essent Fatty Acids 72:203-9. 2005
    ....
  69. ncbi request reprint Identifying and attaining LDL-C goals: mission accomplished? Next target: new therapeutic options to raise HDL-C levels
    Vasilios G Athyros
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Curr Drug Targets 8:483-8. 2007
    ..HDL-C strategies, in combination with effective statins, are a new drug target aimed at a further reduction in CVD morbidity and mortality compared with statin monotherapy...
  70. ncbi request reprint Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia
    George Liamis
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    J Investig Med 55:36-44. 2007
    ..Here we attempt to illuminate the pathophysiology of diuretic-induced hyponatremia by focusing on uric acid homeostasis. Additionally, we analyze the epidemiology and clinical characteristics of the disorder...
  71. ncbi request reprint Antibodies against various forms of mildly oxidized low-density lipoprotein are not associated with carotid intima-media thickness in patients with primary hyperlipidemia
    Sofia G Tsouli
    Department of Internal Medicine, University of Ioannina, Ioannina, Greece
    Angiology 57:615-22. 2006
    ..This supports the concept that extensively oxidized LDL enriched in aldehydes rather than mildly oxidized LDL may play a prominent role in the early stage of atherosclerosis...
  72. ncbi request reprint Severe hypocholesterolemia with reduced serum lipoprotein(a) in a patient with visceral leishmaniasis
    Evagellos Liberopoulos
    Department of Internal Medicine, University of Ioannina School of Medicine, Greece
    Ann Clin Lab Sci 32:305-8. 2002
    ..Moreover, serum Lp(a) level was markedly reduced on presentation, which is the first published report on Lp(a) levels in kala-azar. Possible mechanisms for the observed alterations of the serum lipid profile are discussed...
  73. ncbi request reprint Should atenolol still be recommended as first-line therapy for primary hypertension?
    Asterios Karagiannis
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Hellenic J Cardiol 47:298-307. 2006
  74. ncbi request reprint Reduced PAF-acetylhydrolase activity associated with Lp(a) in patients with coronary artery disease
    Loukas D Tsironis
    Laboratory of Biochemistry, Department of Chemistry, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Atherosclerosis 177:193-201. 2004
    ..The consequences of this phenomenon as regards the pathophysiological role of Lp(a) in atherosclerosis remain to be established...
  75. ncbi request reprint Apolipoprotein E and renal disease
    Evagelos Liberopoulos
    Department of Internal Medicine, University of Ioannina, Ioannina, Greece
    Am J Kidney Dis 43:223-33. 2004
    ..Finally, certain mutations of the ApoE gene are associated with a recently described nephropathy, termed lipoprotein glomerulopathy...
  76. doi request reprint Cardiovascular risk factors and estimated 10-year risk of fatal cardiovascular events using various equations in Greeks with metabolic syndrome
    Theodoros Chimonas
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Angiology 61:49-57. 2010
    ..This might justify local risk engine evaluation in event-based studies. (Clinical-Trials.gov ID: NCT00416741)...
  77. doi request reprint A review of drug-induced hyponatremia
    George Liamis
    Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece
    Am J Kidney Dis 52:144-53. 2008
    ..Here, we review clinical information about the incidence of hyponatremia associated with specific drug treatment and discuss the underlying pathophysiologic mechanisms...
  78. ncbi request reprint Clinical and laboratory characteristics of hypernatraemia in an internal medicine clinic
    George Liamis
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Nephrol Dial Transplant 23:136-43. 2008
    ..Also, we sought to identify differences between patients who were admitted with hypernatraemia and those who developed hypernatraemia during hospitalization...
  79. ncbi request reprint Apolipoprotein E polymorphism in northwestern Greece: frequency and effect on lipid parameters
    Evagelos Liberopoulos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Ann Clin Lab Sci 34:347-54. 2004
    ..In conclusion, the results of our study suggest that ethnic differences, as well as alterations of serum apoE levels, significantly modify the relationship between apoE gene polymorphism and serum lipid variability...
  80. ncbi request reprint Are the effects of tamoxifen on the serum lipid profile modified by apolipoprotein E phenotypes?
    Evagellos Liberopoulos
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Oncology 62:115-20. 2002
    ..The ApoE phenotype also affects lipid responses to diets or treatment with statins. However, the effect of tamoxifen on the lipid profile in different ApoE phenotypes is unknown...