Research Topics
Genomes and GenesSpecies | Konstantinos CharalabopoulosSummaryAffiliation: University of Ioannina Country: Greece Publications
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Publications
Public knowledge, beliefs and practices in Greece about cancer etiology and preventionK Charalabopoulos
Department of Physiology, Clinical Unit, loannina University Medical School, loannina, Greece
East Mediterr Health J 17:392-7. 2011..A reconsideration of the policy regarding health education programmes concerning cancer prevention in Greece is needed...- Effects of cigarette smoking on the antioxidant defence in young healthy male volunteersK Charalabopoulos
Department of Physiology, Clinical Unit, Ioannina University Medical School, Ioannina, Greece
Int J Clin Pract 59:25-30. 2005..They exhibit, however, a higher plasma antioxidant capacity, but a significantly reduced ability of blood lymphocytes, to resist to H2O2-induced DNA damage... - Integrin receptors and extracellular matrix components in parotid neoplasmsKonstantinos Charalabopoulos
Department of Physiology, Medical Faculty, University of Ioannina, Ioannina, Greece
Exp Oncol 27:2-6. 2005..The role of dysregulation of the expression of these proteins in invasion and metastasis of parotid tumors is discussed... - Consequences of the discontinuation of antihypertensive treatment in successfully treated patientsK Charalabopoulos
Department of Physiology, University of Ioannina, Ioannina, Greece
Int J Clin Pract 59:704-8. 2005..In this study, we discuss the available data regarding the consequences of antihypertensive drug withdrawal in successfully treated patients and we suggest guidelines for the application in clinical practice... - Integrins adhesion molecules and some of their ligands in laryngeal cancerKonstantinos Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Greece
Exp Oncol 27:86-90. 2005..So, further studies are necessary to establish the importance of these markers to early larynx cancer diagnosis and reach the decision on appropriate therapeutic strategies in the management of those patients... - Low selenium levels in serum and increased concentration in neoplastic tissues in patients with colorectal cancer: Correlation with serum carcinoembryonic antigenKonstantin Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Scand J Gastroenterol 41:359-60. 2006 - Serum and tissue selenium levels in gastric cancer patients and correlation with CEAKonstantinos Charalabopoulos
Department of Physiology, Medical Faculty, University of Ioannina, Ioannina, Greece
Anticancer Res 29:3465-7. 2009..An inverse relationship between selenium (Se) intake and cancer mortality is evident in humans... - The clinical significance of soluble E-cadherin in nonsmall cell lung cancerK Charalabopoulos
Department of Physiology, Clinical Unit, Ioannina University Medical Faculty, Greece
Exp Oncol 28:83-5. 2006..In the present study the clinical significance of serum levels of soluble E-cadherin (sE-cad) in newly diagnosed patients with non small cell lung cancer (NSCLC) was investigated... - Rare association of chronic lymphocytic thyroiditis with dermatomyositisKonstantinos Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Greece
Arch Med Res 37:563-5. 2006..We consider that both are developed from the same autoimmune background. Herein, we present a case of a 30-year-old man with a 4-year history of AITD who was diagnosed as suffering as well from DM... - The role of CD44 adhesion molecule in oral cavity cancerA Georgolios
Department of Physiology, Division of Adhesion Molecules, Ioannina University Medical School, Ioannina, Greece
Exp Oncol 28:94-8. 2006..This review is focused on the role of CD44 in the carcinogenesis of the oral cavity with special emphasis on its potential use for diagnosis and prognosis of cancer of oral cavity... - Selenium in serum and neoplastic tissue in breast cancer: correlation with CEAK Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, 13, Solomou Str, 452 21 Ioannina, Greece
Br J Cancer 95:674-6. 2006..The decrease in serum Se concentration as well as its increased concentration in the neoplastic breast tissue is of great significance. These alterations may reflect part of the defence mechanisms against the carcinogenetic process... - Alterations in arterial blood parameters in patients with liver cirrhosis and ascitesKonstantinos Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Int J Med Sci 4:94-7. 2007..As a result, pulmonary resistance is impaired and patients more likely succumb to infections and adult respiratory distress syndrome... - CEA levels in serum and BAL in patients suffering from lung cancer: correlation with individuals presenting benign lung lesions and healthy volunteersKonstantinos Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Med Oncol 24:219-25. 2007..CEA is synthesized by epithelial and tumor cells. In this study, CEA levels in sera and bronchoalveolar lavage fluid (BAL) were measured in patients with malignant lung cancer and benign lung diseases... - Acute septic cholelithiasic cholecystitis and adenocarcinoma of the gallbladder; an interesting associationA Charalampopoulos
Third Department of Surgery, Athens University Medical School, Athens, Greece
Acta Gastroenterol Belg 70:267-70. 2007..The goal of the present study is to examine the relation between severe septic complications of lithiasic cholecystitis and primary carcinoma of the gallbladder... - Giardia lamblia intestinalis: a new pathogen with possible link to Kikuchi-Fujimoto disease. An additional element in the disease jigsawK Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Int J Clin Pract 58:1180-3. 2004..The patient's age in combination with this firstly reported protozoal pathogen, as a triggering agent leading to KFD, consist a very interesting originality. Additionally, some review data is also given... - Cadherin superfamily of adhesion molecules in primary lung cancerK Charalabopoulos
Department of Physiology, Clinical Unit, Medical School, University of Ioannina, Ioannina, Greece
Exp Oncol 26:256-60. 2004..In conclusion, many studies are in process and it is very possible that soon some cadherins will be used as useful biomarkers and theraupeutic targets in cases of primary lung cancer... - Brucella melitensis infection stimulates an immune response leading to Kikuchi-Fujimoto diseaseKonstantin Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, 13, Solomou Str, 452 21 Ioannina, Greece
In Vivo 17:51-3. 2003..To our best knowledge, in the English language bibliography, this is the first reported case worldwide, though another similar case was described in the Spanish literature ten years ago... - Kikuchi-Fujimoto disease in Greece. A study of four cases and review of the literatureKonstatin Charalabopoulos
Department of Physiology, Ioannina University Medical School, Ioannina, Greece
In Vivo 16:311-6. 2002..We describe four cases of Kikuchi-Fujimoto disease observed in Greece. Their characteristics are discussed, whilst a review of the literature is attempted... - Antitumour and toxic effects on Wistar rats of two new platinum complexesK Charalabopoulos
University of Ioannina, Ioannina, Greece
Eur J Clin Invest 32:129-33. 2002..Cancer chemotherapy in humans based on metal complexes started at the clinical level in the late 1970s with the use of cisplatin, which forms intra-strand cross-links with DNA... - Is implant pacemaker a physicochemical cause triggering Kikuchi-Fujimoto disease?Konstantin Charalabopoulos
Dept of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, 13 Solomou str, 452 21 Ioannina, Greece
In Vivo 16:73-6. 2002..Hereby, we hypothesize that the implant pacemaker can act as a physicochemical agent triggering Kikuchi-Fujimoto disease. We present this case and we discuss various disease aspects. A brief review of the literature is also given... - Direct endobronchial metastasis is a rare metastatic pattern in breast cancerK Charalabopoulos
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Int J Clin Pract 58:641-4. 2004..Hereby, review data from the literature is given in brief... - Penetration of antimicrobial agents into the prostateKonstantin Charalabopoulos
Department of Physiology, Clinical Unit, Ioannina University Medical School, Ioannina, Greece
Chemotherapy 49:269-79. 2003..Good to excellent penetration into prostatic fluid and tissue has been demonstrated with many antimicrobial agents, including tobramycin, netilmicin, tetracyclines, macrolides, quinolones, sulfonamides and nitrofurantoin... - Comparison of the dysadherin and E-cadherin expression in primary lung cancer and metastatic sitesAntigony Mitselou
Department of Forensic Pathology, Ioannina University Medical School, Ioannina, Greece
Histol Histopathol 25:1257-67. 2010..In lung carcinomas dysadherin expression seems to reflect tumour aggressiveness and may be considered a positive marker of poor prognosis when considered alone or/and in combination with down-regulation of E-cadherin... - Expression patterns of dysadherin and E-cadherin in lymph node metastases of colorectal carcinomaAnna Batistatou
Department of Pathology, University of Ioannina Medical School, University Campus, PO Box 1186, 451 10, Ioannina, Greece
Virchows Arch 448:763-7. 2006..Our results suggest that different mechanisms govern E-cadherin expression in the primary tumor and the corresponding lymph node metastases... - Differential expression of dysadherin in papillary thyroid carcinoma and microcarcinoma: correlation with E-cadherinAnna Batistatou
Department of Pathology, University of Ioannina Medical School, University Campus, P O Box 1186, 451 10, Ioannina, Greece
Endocr Pathol 19:197-202. 2008..Increased dysadherin expression is possibly one of the post-transcriptional mechanisms responsible for E-cadherin downregulation in thyroid papillary neoplasia... - Anticancer and cytotoxic effects of a triorganotin compound with 2-mercapto-nicotinic acid in malignant cell lines and tumor bearing Wistar ratsIoannis I Verginadis
Department of Physiology, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece
Eur J Pharm Sci 42:253-61. 2011..05). It is noteworthy to mention that the 30% (3 out of 10) of the bearing animals were totally cured. These findings indicate that SnMNA might be a promising new antitumor agent... - Parathormone and 1,25(OH)2D3 but not 25(OH)D3 serum levels, in an inverse correlation, reveal an association with advanced stages of colorectal cancerAnestis Charalampopoulos
Department of Surgery, Medical Faculty, University of Athens, Attikon Hospital, Athens, Greece
Clin Exp Med 10:69-72. 2010..Low serum levels of 1,25(OH)(2)D(3) on one hand and increased levels of PTH in patients with CRC on the other might be strongly related to the carcinogenetic process... - Combined use of antisense oligonucleotides and chemotherapeutics in the treatment of refractory prostate cancerDimitrios Baltogiannis
Department of Urology, Ioannina University Medical School, Ioannina, Greece
Exp Oncol 27:91-3. 2005..Although numerous chemotherapeutic regimens have been evaluated for patients with hormone-refractory prostate cancer, none has improved survival... - Early gastric carcinoma with oncocytic features and extensive metastasesAnna Batistatou
Department of Pathology, University of Ioannina Medical School, Ioannina 451 10, Greece
Pathol Res Pract 203:539-41. 2007..The biologic behavior of oncocytic adenocarcinoma of the stomach is still unclear. We would like to present this case, so that its clinicopathological characteristics can be added to the few cases already published... - Physiology and pathophysiology of selectins, integrins, and IgSF cell adhesion molecules focusing on inflammation. A paradigm model on infectious endocarditisChristos Golias
Department of Physiology, Medical Faculty, Democritus University of Thrace, Alexandroupolis, Greece
Cell Commun Adhes 18:19-32. 2011..In this review a paradigm focusing on cell adhesion molecules pathophysiology and infective endocarditis development is given... - Iliopsoas abscesses: diagnostic, aetiologic and therapeutic approach in five patients with a literature reviewAnestis Charalampopoulos
Third Department of General Surgery, Athens University Medical School, Attikon University Hospital, Athens, Greece
Scand J Gastroenterol 44:594-9. 2009..The purpose of the study was to present five cases with iliopsoas abscesses based on the rarity of this clinical entity... - Dysadherin expression in head and neck squamous cell carcinoma: association with lymphangiogenesis and prognostic significancePanayiotis A Kyzas
Department of Pathology, University of Ioannina, Medical School, Ioannina, Greece
Am J Surg Pathol 30:185-93. 2006..Dysadherin expression might be a promising prognostic marker for separation of patients at higher risk... - The E-cadherin adhesion molecule and colorectal cancer. A global literature approachElena Tsanou
Department of Pathology Cytology, Medical School, University of Ioannina, Ioannina, Greece
Anticancer Res 28:3815-26. 2008..This should aid the development of novel strategies for both prevention and treatment of cancer... - Biological studies of new organotin(IV) complexes of thioamide ligandsMarianna N Xanthopoulou
Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece
Eur J Med Chem 43:327-35. 2008..Compounds (1)-(6) were finally tested for in vitro cytotoxicity against leiomyosarcoma cells... - The role of lymphadenectomy in renal cancer surgery. An updateXenophon Giannakopoulos
Department of Urology, Medical Faculty, University of Ioannina, Ioannina, Greece
Exp Oncol 26:261-4. 2004..Nowdays, it seems that the complete lymph node dissection does not demonstrate any survival benefit over the radical nephrectomy alone... - Quality of life survey in patients with advanced prostate cancerXenophon Giannakopoulos
Department of Urology, Medical Faculty, University of Ioannina, Ioannina, Greece
Exp Oncol 27:13-7. 2005..Modern QoL questionnaires are considered to be more than a necessity nowadays for the improvement of the treatment administered from the physician and the performance and functional status of the patient... - First case of fatal pulmonary peliosis without any other organ involvement in a young testosterone abusing maleTheodore Vougiouklakis
Department of Forensic Medicine, Clinical Unit, Medical School, University of Ioannina, Ioannina, Greece
Forensic Sci Int 186:e13-6. 2009..To our knowledge this is the third reported case of pulmonary peliosis and the first one that is not associated with peliosis of any other organ... - A new concept of melanocytic neoplasia pathogenesis based on the phenotype of common acquired neviAnna Batistatou
Department of Pathology, University of Ioannina Medical School, University Campus, P O Box 1186, 451 10 Ioannina, Greece
Med Hypotheses 69:1334-9. 2007.... - Crossing chromosomes in pleomorphic sarcomaA Batistatou
Department of Pathology, University of Ioannina Medical School, Ioannina, Greece
Exp Oncol 28:248. 2006 - Lung, pleural and colon actinomycosis in an immunocompromised patient: a rare form of presentationK Charalabopoulos
Department of Physiology, Clinical Unit, Ioannina University Medical School, Ioannina, Greece
Chemotherapy 49:209-11. 2003..Clinical manifestations and treatment are discussed. Actinomycetes are rarely opportunistic agents in immunocompromised patients; thus the disease deserves special attention in those patients... - In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherinA Batistatou
Department of Pathology, University of Ioannina Medical School, P O Box 1186, Ioannina 45110, Greece
Br J Cancer 96:1404-8. 2007..Dysadherin may play an important role in breast cancer progression by promoting invasion and, particularly in lobular carcinomas, it might also be used as a marker of invasion... - Synthesis, structural characterization and in vitro cytotoxicity of organotin(IV) derivatives of heterocyclic thioamides, 2-mercaptobenzothiazole, 5-chloro-2-mercaptobenzothiazole, 3-methyl-2-mercaptobenzothiazole and 2-mercaptonicotinic acidMarianna N Xanthopoulou
Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece
J Inorg Biochem 96:425-34. 2003..Compound 5 exhibits strong cytotoxic activity, while complexes 1 and 3 show less cytotoxic activity... - Fever of unknown origin in carcinoma of the colonGeorge N Karachalios
Department of Medicine, Red Cross Hospital, Athens, Greece
Med Princ Pract 13:169-70. 2004..To report a case of fever of unknown origin in a patient with carcinoma of the colon but without gastrointestinal symptoms... - Fishing for vascular invasionAnna Batistatou
Department of Pathology, University of Ioannina Medical School, Ioannina, Greece
Int J Surg Pathol 15:68. 2007 - Role and expression patterns of E-cadherin in head and neck squamous cell carcinoma (HNSCC)A Georgolios
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
J Exp Clin Cancer Res 25:5-14. 2006..Controversies in the results of various studies are discussed and possible prospects for application of all this developing knowledge to prognosis and therapy of the disease are briefly mentioned... - Synthesis, characterization and biological studies of new antimony(III) halide complexes with ω-thiocaprolactamIbrahim I Ozturk
Department of Chemistry, Namik Kemal University, Tekirdag, Turkey
J Inorg Biochem 109:57-65. 2012..The results were shown negligible inhibitory activity of 1-3 against LOX... - Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literatureDimitrios Tsapralis
Department of Pathology, Athens University Medical School, Attikon University Hospital, Athens, Greece
Diagn Pathol 5:4. 2010.... - Effect of perioperative immuno-enhanced enteral nutrition on inflammatory response, nutritional status, and outcomes in head and neck cancer patients undergoing major surgeryDimitrios Felekis
Medical School, University of Athens, Hippokration Hospital, Athens, Greece
Nutr Cancer 62:1105-12. 2010..Perioperative enteral immuno-enhanced feeding in head and neck cancer patients undergoing major surgery may influence the postoperative outcomes by reducing the frequency rate of infections and wound complications... - Breast carcinoma metastasis to the orbit and paranasal sinuses: a case reportIoannis Asproudis
The Department of Ophthalmology, Medical Faculty, University of Ioannina, Ioannina, Greece
Exp Oncol 26:246-8. 2004..We present the symptoms, the ophthalmic signs and the imaging techniques that aided the localization of these metastasis, while literature review shows that such combination is rare... - Immunohistochemical analysis of expression of bcl-2 protein in papillary carcinomas and papillary microcarcinomas of the thyroid glandAntigony Mitselou
Department of Forensic Pathology, Medical School, University of Ioannina, Greece
Exp Oncol 26:282-6. 2004..To compare the expression of anti-apoptotic protein bcl-2 and tissue proliferation Ki-67 antigen in tissues of human papillary thyroid carcinoma (PTC) and papillary thyroid microcarcinoma (PTMC)... - Inhibition of benzo(a)pyrene-induced carcinogenesis by vitamin C alone and by vitamin C/vitamin E and selenium/glutathioneK Charalabopoulos
Department of Experimental Physiology, Faculty of Medicine, University of Ioannina, Ioannina, Greece
Biol Trace Elem Res 93:201-12. 2003..This is considered a potent anticarcinogenic effect. The question of an additional supportive administration of such agents complementary to the conventional cancer chemotherapy in humans is raised. Of course, further studies are needed... - Expression patterns of cyclins D1, E in laryngeal epithelial lesions: correlation with other cell cycle regulators (p53, pRb, Ki-67 and PCNA) and clinicopathological featuresE Ioachim
Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
J Exp Clin Cancer Res 23:277-83. 2004..In addition, their expression may be involved in the development of laryngeal lesions, implicated in cell proliferation, with other cell cycle related proteins, probably by different molecular pathways... - E-cadherin adhesion molecule and syndecan-1 expression in various thyroid pathologiesA Mitselou
Department of Forensic Pathology, Medical School, University of Ioannina, Ioannina, Greece
Exp Oncol 29:54-60. 2007.... - Ruptured hemangioma of the umbilical cord and intrauterine fetal death, with review dataTheodoros Vougiouklakis
Department of Forensic Pathology, Medical School, University of Ioannina, Ioannina Greece
Pathol Res Pract 202:537-40. 2006..Associated malformations and complications of the umbilical cord hemangioma are reviewed... - Biliary excretion of antimicrobial drugsGeorge Karachalios
Department of Medicine and Division of Infectious Diseases, Red Cross Hospital, Athens, Greece
Chemotherapy 48:280-97. 2002..We present a review of a large number of antimicrobial agents most commonly used in daily clinical practice, with regard to their biliary excretion... - Withdrawal syndrome following cessation of antihypertensive drug therapyG N Karachalios
Department of Medicine, Red Cross Hospital, Athens, Greece
Int J Clin Pract 59:562-70. 2005..In this study regarding the withdrawal syndrome that follows cessation of antihypertensive drugs therapy, a reference to the abrupt discontinuation of the main categories of antihypertensive drugs is also attempted... - The role of E-cadherin/catenin complex in laryngeal cancerE Mittari
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Exp Oncol 27:257-61. 2005..Further studies are needed to establish the importance of the E-cadherin/catenin complex as a potential biomarker in laryngeal cancer diagnosis and prognosis... - Cell proliferation and cell cycle control: a mini reviewC H Golias
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Int J Clin Pract 58:1134-41. 2004.... - Immunohistochemical evaluation of cathepsin D in normal, hyperplastic and malignant endometrium: correlation with hormone receptor status c-erbB-2, p53, Rb proteins and proliferation associated indicesE Ioachim
Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
Int J Gynecol Cancer 13:344-51. 2003..015). The data show that down-regulation of CD expression is an early event in endometrial carcinogenesis. In addition, stromal cell CD expression may be involved in cell growth process in endometrial carcinomas... - Expression of matrix metalloproteinase-9 (gelatinase B) in benign, premalignant and malignant laryngeal lesionsD Peschos
Department of Forensic Medicine, Medical School, University of Ioannina, Ioannina, Greece
Histol Histopathol 21:603-8. 2006.... - Integrin receptors in primary lung cancerA Gogali
Departments of Pneumonology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Exp Oncol 26:106-10. 2004..Additionally, since the ability of malignant cells to interact with extracellular matrix components is thought to be important, integrin dependent migration of lung cancer cells is a crucial process... - Amplification and co-regulators of androgen receptor gene in prostate cancerCh Golias
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina 45100, Greece
Exp Oncol 31:3-8. 2009.... - Left atrial myxoma prolapsing into the left ventricle. Case report and review of the literatureG Karachalios
Department of Medicine, Red Cross Hospital, Athens, Greece
Chemotherapy 50:297-301. 2004..Combined therapy, consisting of surgical management and antimicrobial therapy, was used. Clinical presentation, diagnosis and treatment are reviewed... - Integrins in head and neck squamous cell carcinoma (HNSCC): a review of the current literatureA K Georgolios
Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
Cell Commun Adhes 12:1-8. 2005.... - Genetic models of human cancer as a multistep process. Paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukaemiaA Karakosta
Dept. of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece
J Exp Clin Cancer Res 24:505-14. 2005.... - The role of cadherin/catenin complex in malignant melanomaN Bonitsis
Department of Physiology, Clinical Unit, Ioannina University Medical School, Ioannina, Greece
Exp Oncol 28:187-93. 2006..In addition, a discussion regarding the role of placental P-cadherin and vascular endothelial VE-cadherin as well as the recently identified molecule of dysadherin, is attempted in brief... - Acute pancreatitis associated with brucellosisDemetrios Papaioannides
Department of Medicine, Arta General Hospital, Greece
JOP 7:62-5. 2006..Acute pancreatitis can be caused by a variety of infectious agents but it is regarded as an extremely rare complication of brucellosis... - Orbital metastasis from verrucous carcinoma of the oral cavity: case report and review of the literatureIoannis Asproudis
Department of Ophthalmology, University Hospital of loannina, Greece
In Vivo 21:909-12. 2007..No other case of this entity, which usually presents as a slow-growing lesion enlarging with direct extension rather than frank invasion, metastasizing to the orbit has been reported in relevant literature...