Maria Bai

Summary

Affiliation: University of Ioannina
Country: Greece

Publications

  1. ncbi Surface topography and ultrastructural changes of mucinous carcinoma breast cells
    G E Voloudakis
    Department of Electron Microscopy Cell Biology, G Papanikolaou Research Center of Oncology and Experimental Surgery, Saint Savas Anticancer Hospital, Athens, Greece
    Ultrastruct Pathol 31:263-71. 2007
  2. ncbi In vivo cell kinetics in breast carcinogenesis
    M Bai
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Breast Cancer Res 3:276-83. 2001
  3. ncbi Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients
    Markos Mihalatos
    Molecular Biology Research Center HYGEIA Antonis Papayiannist, Athens, Greece
    BMC Cancer 5:40. 2005
  4. ncbi Immunohistochemical expression of retinoblastoma gene product (Rb), p53 protein, MDM2, c-erbB-2, HLA-DR and proliferation indices in human urinary bladder carcinoma
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Greece
    Histol Histopathol 15:721-7. 2000
  5. ncbi Mucoepidermoid carcinoma of the thymus: a case presentation and a literature review
    D Stefanou
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Pathol Res Pract 200:567-73. 2004
  6. ncbi Tumor markers in cancer patients. an update of their prognostic significance. Part II
    N J Agnantis
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    In Vivo 18:481-8. 2004
  7. ncbi Tumor markers. An update approach for their prognostic significance. Part I
    N J Agnantis
    Department of Pathology, Medical School, University of Ioannina, University Campus, 45110 Ioannina, Greece
    In Vivo 17:609-18. 2003
  8. ncbi Clinicopathological study of the expression of syndecan-1 in invasive breast carcinomas. correlation with extracellular matrix components
    E Tsanou
    Dept of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    J Exp Clin Cancer Res 23:641-50. 2004
  9. ncbi Clinicopathological study of metallothionein immunohistochemical expression, in benign, borderline and malignant ovarian epithelial tumors
    N Zagorianakou
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Histol Histopathol 21:341-7. 2006
  10. ncbi Clinicopathological study of the expression of hsp27, pS2, cathepsin D and metallothionein in primary invasive breast cancer
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Greece
    Breast 12:111-9. 2003

Collaborators

Detail Information

Publications72

  1. ncbi Surface topography and ultrastructural changes of mucinous carcinoma breast cells
    G E Voloudakis
    Department of Electron Microscopy Cell Biology, G Papanikolaou Research Center of Oncology and Experimental Surgery, Saint Savas Anticancer Hospital, Athens, Greece
    Ultrastruct Pathol 31:263-71. 2007
    ....
  2. ncbi In vivo cell kinetics in breast carcinogenesis
    M Bai
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Breast Cancer Res 3:276-83. 2001
    ..In the transition from hyperplasia to preinvasive lesions there is an imbalance in favour of apoptosis...
  3. ncbi Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients
    Markos Mihalatos
    Molecular Biology Research Center HYGEIA Antonis Papayiannist, Athens, Greece
    BMC Cancer 5:40. 2005
    ..The vast majority of APC mutations are point mutations or small insertions/deletions which lead to truncated protein products. Splicing mutations or gross genomic rearrangements are less common inactivating events of the APC gene...
  4. ncbi Immunohistochemical expression of retinoblastoma gene product (Rb), p53 protein, MDM2, c-erbB-2, HLA-DR and proliferation indices in human urinary bladder carcinoma
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Greece
    Histol Histopathol 15:721-7. 2000
    ..In addition, p53 and HLA-DR antigen expression could be indicators of aggressive behavior of bladder cancer...
  5. ncbi Mucoepidermoid carcinoma of the thymus: a case presentation and a literature review
    D Stefanou
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Pathol Res Pract 200:567-73. 2004
    ..In case of the absence of metastatic disease or other common primary neoplasms of the thymus, the diagnosis of a mucoepidermoid thymic carcinoma should be taken into consideration, although this tumor is rare...
  6. ncbi Tumor markers in cancer patients. an update of their prognostic significance. Part II
    N J Agnantis
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    In Vivo 18:481-8. 2004
    ..Intratumoral angiogenesis is a putative prognostic indicator for some types of cancer. High expression of the angiogenic factor VEGF is associated with angiogenesis and an unfavourable survival...
  7. ncbi Tumor markers. An update approach for their prognostic significance. Part I
    N J Agnantis
    Department of Pathology, Medical School, University of Ioannina, University Campus, 45110 Ioannina, Greece
    In Vivo 17:609-18. 2003
    ..Other markers e.g., the p53 gene, look promising as prognostic factors in different kinds of cancer...
  8. ncbi Clinicopathological study of the expression of syndecan-1 in invasive breast carcinomas. correlation with extracellular matrix components
    E Tsanou
    Dept of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    J Exp Clin Cancer Res 23:641-50. 2004
    ..0067). The results of the present study show the implication of this protein in the remodeling of breast cancer tissue, through the interaction with other extracellular matrix components, probably influences the tumour progression...
  9. ncbi Clinicopathological study of metallothionein immunohistochemical expression, in benign, borderline and malignant ovarian epithelial tumors
    N Zagorianakou
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Histol Histopathol 21:341-7. 2006
    ..MT constitutes a marker that characterizes aggressiveness and a high malignant potential in ovarian epithelial tumors. In diagnostic problems MT may help distinguish between benign, borderline and malignant tumors...
  10. ncbi Clinicopathological study of the expression of hsp27, pS2, cathepsin D and metallothionein in primary invasive breast cancer
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Greece
    Breast 12:111-9. 2003
    ....
  11. ncbi B-cell differentiation immunophenotypes in classical Hodgkin lymphomas
    Maria Bai
    Department of Pathology, University of Ioannina, Ioannina, Greece
    Leuk Lymphoma 47:495-501. 2006
    ....
  12. ncbi Expression of matrix metalloproteinase-9 (gelatinase B) in benign, premalignant and malignant laryngeal lesions
    D Peschos
    Department of Forensic Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Histol Histopathol 21:603-8. 2006
    ....
  13. ncbi Immunohistochemical study of angiogenesis and proliferative activity in epiretinal membranes
    E Tsanou
    Department of Pathology-Cytology, Medical School, University of Ioannina, Ioannina, Greece
    Int J Clin Pract 59:1157-61. 2005
    ..Our study confirms the presence of vascularisation in PDR membranes, as well as the presence of VEGF even in avascular PVR membranes, suggesting that immunoreactivity for VEGF may not be accompanied by angiogenesis...
  14. ncbi Low expression of p27 protein combined with altered p53 and Rb/p16 expression status is associated with increased expression of cyclin A and cyclin B1 in diffuse large B-cell lymphomas
    M Bai
    Department of Pathology, Medical Faculty, University of Ioannina, 45110, Ioannina, Greece
    Mod Pathol 14:1105-13. 2001
    ..These findings suggest combined impairment of a complex cell-cycle control network involving the CDK inhibitor p27, the P53 pathway, and the Rb1 pathway, which exerts a cooperative effect resulting in enhanced tumor cell proliferation...
  15. ncbi E-cadherin adhesion molecule and syndecan-1 expression in various thyroid pathologies
    A Mitselou
    Department of Forensic Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Exp Oncol 29:54-60. 2007
    ....
  16. ncbi Glycoprotein CD44 expression in normal, hyperplasic and neoplastic endometrium. An immunohistochemical study including correlations with p53, steroid receptor status and proliferative indices (PCNA, MIB1)
    N Zagorianakou
    Department of Pathology, Medical School, University of Ioannina, Greece
    Eur J Gynaecol Oncol 24:500-4. 2003
    ....
  17. ncbi In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin
    A Batistatou
    Department of Pathology, University of Ioannina Medical School, P O Box 1186, Ioannina 45110, Greece
    Br J Cancer 96:1404-8. 2007
    ..Dysadherin may play an important role in breast cancer progression by promoting invasion and, particularly in lobular carcinomas, it might also be used as a marker of invasion...
  18. ncbi Estrogen receptor beta (ERbeta) expression in breast carcinomas is not correlated with estrogen receptor alpha (ERalpha) and prognosis: the Greek experience
    D Stefanou
    Department of Pathology, University of Ioannina, Medical School, Ioannina, Greece
    Eur J Gynaecol Oncol 25:457-61. 2004
    ..Our findings contribute to the better understanding of the role of ERbeta in breast cancer...
  19. ncbi Expression patterns of cyclins D1, E in laryngeal epithelial lesions: correlation with other cell cycle regulators (p53, pRb, Ki-67 and PCNA) and clinicopathological features
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    J Exp Clin Cancer Res 23:277-83. 2004
    ..In addition, their expression may be involved in the development of laryngeal lesions, implicated in cell proliferation, with other cell cycle related proteins, probably by different molecular pathways...
  20. ncbi Cell cycle proteins in laryngeal cancer: role in proliferation and prognosis
    D Peschos
    Forensic Medicine, Medical School, University of Ioannina, Ioannina, Greece
    J Exp Clin Cancer Res 24:431-7. 2005
    ..Furthermore, levels of CDKIs, although they act as cell cycle activity blockers, are not reliable markers for the estimation of laryngeal neoplastic cells growth fraction...
  21. ncbi Expression of the cell-cycle regulatory proteins (cyclins D1 and E) in endometrial carcinomas: correlations with hormone receptor status, proliferating indices, tumor suppressor gene products (p53, pRb), and clinicopathological parameters
    A Mitselou
    Department of Forensic Pathology, Medical School, University of Ioannina, Greece
    Eur J Gynaecol Oncol 25:719-24. 2004
    ..Immunoexpression of cyclin D1 does not appear to be associated with cell-cycle progression in the benign or malignant endometrium...
  22. ncbi Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas
    Maria Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Ioannina 45110, Greece
    Hum Pathol 38:103-13. 2007
    ....
  23. ncbi High levels of topoisomerase IIalpha protein expression in diffuse large B-cell lymphoma are associated with high proliferation, germinal center immunophenotype, and response to treatment
    George Pentheroudakis
    Department of Medical Oncology, Ioannina University Hospital, Ioannina, Greece
    Leuk Lymphoma 51:1260-8. 2010
    ..008). Although TopoIIa gene copy number abnormalities were not found in DLBCL, high levels of protein expression are associated with GCB-cell differentiation immunophenotype, high proliferation, and response to treatment...
  24. ncbi CD44s expression, in benign, borderline and malignant tumors of ovarian surface epithelium. Correlation with p53, steroid receptor status, proliferative indices (PCNA, MIB1) and survival
    N Zagorianakou
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Anticancer Res 24:1665-70. 2004
    ..CONCLUSION: The current study demonstrates that CD44s may be functionally involved in the pathogenesis of epithelial ovarian lesions...
  25. ncbi Near-absolute expression of the bcl-2 protein identifies a subgroup of stage II breast cancer patients with a most favorable outcome. Results of a clinicopathological study
    E Briasoulis
    Dept of Medical Oncology, School of Medicine, University of Ioannina, Greece
    J Exp Clin Cancer Res 20:341-4. 2001
    ....
  26. ncbi Alterations of the p53, Rb and p27 tumor suppressor pathways in diffuse large B-cell lymphomas
    Maria Bai
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Anticancer Res 27:2345-52. 2007
    ..This might explain, at least partially, the association between concurrent aberrations of the p53, Rb and p27 pathways and aggressive clinical behavior in DLBCL...
  27. ncbi Increased expression of the bcl6 and CD10 proteins is associated with increased apoptosis and proliferation in diffuse large B-cell lymphomas
    M Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece
    Mod Pathol 16:471-80. 2003
    ....
  28. ncbi Immunohistochemical expression of superoxide dismutase (MnSOD) anti-oxidant enzyme in invasive breast carcinoma
    E Tsanou
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Histol Histopathol 19:807-13. 2004
    ..In addition, MnSOD content varies according to the degree of differentiation of breast carcinoma...
  29. ncbi Expression of cyclin-dependent kinases inhibitors p21(WAF1) and p27(KIP1) in benign, premalignant and malignant laryngeal lesions. correlation with cell cycle regulatory proteins
    D Peschos
    Department of Forensic Medicine, Medical School, University of Ioannina, 45110 Ioannina, Greece
    In Vivo 18:719-24. 2004
    ..05). CONCLUSION: Due to the increased expression levels of CDKIs in laryngeal carcinomas, we suggest the existence of a mechanism by which tumor cells tolerate the inhibitory effect of these proteins on cell cycle progression...
  30. ncbi Expression patterns of cyclins D1, E and cyclin-dependent kinase inhibitors p21(Waf1/Cip1) and p27(Kip1) in urothelial carcinoma: correlation with other cell-cycle-related proteins (Rb, p53, Ki-67 and PCNA) and clinicopathological features
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Urol Int 73:65-73. 2004
    ..The expression of these proteins was also analyzed along with other cell-cycle-related proteins such as: p53, pRb and the proliferation-associated indices Ki-67 and proliferating cell nuclear antigen (PCNA)...
  31. ncbi Cell cycle and apoptosis deregulation in classical Hodgkin lymphomas
    Maria Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece
    In Vivo 19:439-53. 2005
    ..The present review summarizes data with respect to the cell cycle and apoptosis deregulation in cHL...
  32. ncbi Cluster analysis of apoptosis-associated bcl2 family proteins in diffuse large B-cell lymphomas. Relations with the apoptotic index, the proliferation profile and the B-cell differentiation immunophenotypes
    Maria Bai
    Department of Pathology, University of Ioannina, Ioannina, Greece
    Anticancer Res 24:3081-8. 2004
    ..In order to gain further insight into the apoptosis profile of DLBCL, 79 cases were investigated to determine whether distinct clusters of the combined expression levels of bcl2 family proteins can be identified in these lymphomas...
  33. ncbi p63 expression in benign and malignant breast lesions
    D Stefanou
    Department of Pathology, University of Ioannina Medical School, Ioannina, Greece
    Histol Histopathol 19:465-71. 2004
    ..Regarding papillary neoplasms, it is possible that tumor cells acquire and exhibit at least in part a myoepithelial differentiation program...
  34. ncbi B-cell differentiation, apoptosis and proliferation in diffuse large B-cell lymphomas
    Maria Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece
    Anticancer Res 25:347-62. 2005
    ..The present review summarizes data with respect to the relationships between B-cell differentiation, apoptosis and proliferation in DLBCL...
  35. ncbi Localization of metallothionein in urothelial carcinoma of the human urinary bladder: an immunohistochemical study including correlation with HLA-DR antigen, p53, and proliferation indices
    E E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Greece
    Anticancer Res 21:1757-61. 2001
    ..001) was also detected. The data suggested that MT expression was correlated with a more aggressive behavior in urothelial bladder cancer...
  36. ncbi Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed-Sternberg cells
    Maria Bai
    Department of Pathology, Medical Faculty, University of Ioannina, 45110 Ioannina, Greece
    Mod Pathol 17:1338-45. 2004
    ....
  37. ncbi Immunohistochemical study of extracellular matrix components in epiretinal membranes of vitreoproliferative retinopathy and proliferative diabetic retinopathy
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Eur J Ophthalmol 15:384-91. 2005
    ....
  38. ncbi The enigmatic nature of apocrine breast lesions
    P Zagorianakou
    Department of Pathology, University of Ioannina, Medical School, University Campus, P.O. Box 1186, 45110, Ioannina, Greece
    Virchows Arch 448:525-31. 2006
    ..The purpose of this study is to collect and highlight the areas of consensus in the literature as well as the controversial areas concerning the apocrine epithelium of the breast...
  39. ncbi Immunohistological characterization of thymic dendritic cells
    Alexandra Papoudou-Bai
    Departments of Pathology and Anatomy, Medical School, University of Ioannina, 45110, Ioannina, Greece and
    In Vivo 26:985-92. 2012
    ..Dendritic cells play key roles in thymic histophysiology and histopathology. Therefore, we analyzed the immunotopographical distribution of cells expressing markers of dendritic cells and macrophages in postnatal human thymus...
  40. ncbi Involvement of dysadherin and E-cadherin in the development of testicular tumours
    A Batistatou
    Department of Pathology, University of Ioannina Medical School, Ioannina, Greece
    Br J Cancer 93:1382-7. 2005
    ..In testicular tumours, as in other neoplasms, dysadherin downregulates E-cadherin expression, at least in part...
  41. ncbi The role of fine-needle aspiration biopsy in the management of patients with thyroid nodules
    P Zagorianakou
    Department of Pathology-Cytology, Medical School, University of Ioannina, Greece
    In Vivo 19:605-9. 2005
    ..We conclude that FNA is an effective screening test in the evaluation of the necessity for surgical treatment in patients with thyroid nodules...
  42. ncbi Immunohistochemical expression of vascular endothelial growth factor correlates with positive surgical margins and recurrence in T1 and T2 squamous cell carcinoma (SCC) of the lower lip
    P A Kyzas
    Department of Pathology, Medical School, University of Ioannina, 45 110 Ioannina, Greece
    Oral Oncol 40:941-7. 2004
    ..There was also a significant association of high VEGF expression with a higher incidence of local recurrence (p < 0.001). We suggest that VEGF expression may be used as an index to distinguish patients with higher risk of relapse...
  43. ncbi Immunohistochemical expression patterns of neural and neuroendocrine markers, the neural growth factor receptors and the beta-tubulin II and IV isotypes in human thymus
    Maria Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Greece
    Anticancer Res 28:295-303. 2008
    ..The present results provide further immunohistological evidence that numerous neural and neuroendocrine factors may be required for the development and function of the human thymic microenvironment...
  44. ncbi FNAC: its role, limitations and perspective in the preoperative diagnosis of breast cancer
    P Zagorianakou
    Department of Pathology, Medical School, University of Ioannina, Greece
    Eur J Gynaecol Oncol 26:143-9. 2005
    ..The reliability and efficiency of the method depends on the quality of the samples and the experience of the medical staff that performs the aspiration...
  45. ncbi CD44 family and gynaecological cancer
    G Makrydimas
    Department of Obstetrics and Gynecology, Medical School, University of Ioannina, 45110, Ioannina, Greece
    In Vivo 17:633-40. 2003
    ..This review summarizes the available data on the possible prognostic role of the polymorphic CD44 protein family and its role as a tumor marker in gynaecological cancer...
  46. ncbi The role of tumor markers in non-palpable breast cancers
    A C Goussia
    Department of Pathology, Medical School, University of Ioannina (Greece
    Eur J Gynaecol Oncol 25:559-61. 2004
    ..Further studies are needed to assess the prognostic role of certain biological factors in well-designed clinical studies along with long follow-up of screened patients...
  47. ncbi Immunohistological analysis of cell cycle and apoptosis regulators in thymus
    Maria Bai
    Department of Pathology, University of Ioannina, Greece Electronic address
    Ann Anat . 2012
    ..Furthermore, this study indicates decrease of the proliferation and caspase-dependent apoptosis of thymocytes from the cortex to the medulla...
  48. ncbi Randomized phase II exploratory study of prophylactic amifostine in cancer patients who receive radical radiotherapy to the pelvis
    Konstantinos H Katsanos
    1st Department of Internal Medicine and Hepato Gastroenterology Unit, Medical School of Ioannina, Leoforos Stavrou Niarxou, Ioannina, 451 10, Greece
    J Exp Clin Cancer Res 29:68. 2010
    ..This study aimed to investigate the efficacy of prophylactic amifostine in reducing the risk of severe radiation colitis in cancer patients receiving radical radiotherapy to the pelvis...
  49. ncbi Primary mantle cell lymphoma of the conjunctiva: a case report
    Miltiadis Aspiotis
    Department of Ophthalmology, Medical School, University of Ioannina, Ioannina, Greece
    Virchows Arch 449:472-5. 2006
    ..In this study, we report an extremely rare case of conjunctival mantle cell lymphoma in a 78-year-old man, presenting as a unilateral epibulbar mass...
  50. ncbi Aggressive angiomyxoma of the vagina: a case report and review of the literature
    D J Papachristou
    Department of Pathology, University Hospital of Ioannina, Ioannina, Greece
    Eur J Gynaecol Oncol 25:519-21. 2004
    ..Furthermore, we attempt to enlighten the possible mechanisms that govern the pathogenesis and the biological behavior of this "mysterious" neoplasm...
  51. ncbi Angiotropic large cell lymphoma
    T Vougiouklakis
    Dept of Forensic Pathology, Medical School, University of Ioannina, Ioannina, Greece
    J Exp Clin Cancer Res 23:345-8. 2004
    ..Immunohistochemical studies showed intense positive staining for leukocyte common antigen (LCA), L26 and CD20 and negative staining for Factor VIII- related antigen, and CD5, demonstrated that the neoplastic cells were of B-cell lineage...
  52. ncbi Expression of vascular endothelial growth factor (VEGF) and association with microvessel density in small-cell and non-small-cell lung carcinomas
    D Stefanou
    Department of Pathology, University of Ioannina Medical School, Ioannina, Greece
    Histol Histopathol 19:37-42. 2004
    ..Nevertheless, antiangiogenic therapy should not be targeted specifically to the VEGF pathway, since in SCLCs other mediators of angiogenesis may be important as well...
  53. ncbi Prognostic significance of p53 in the cancer of the larynx
    D Assimakopoulos
    Department of Otorhinolaryngology, University of Ioannina Medical School, 451 10 Ioannina, Greece
    Anticancer Res 20:3555-64. 2000
    ..Immunohistochemical staining techniques and molecular genetics demonstrated that p53 activation is an early event in laryngeal squamous cell carcinogenesis but can not be used as a reliable prognostic marker...
  54. ncbi Rectal Epstein-Barr virus-positive Hodgkin's lymphoma in a patient with Crohn's disease: case report and review of the literature
    Maria Bai
    Department of Pathology, Medical School, University of Ioannina, GR-451 10 Ioannina, Greece
    Scand J Gastroenterol 41:866-9. 2006
    ....
  55. ncbi Immunohistochemical expression of heat shock protein 27, in normal hyperplastic and neoplastic endometrium: correlation with estrogen and progesterone receptor status, p53, pRb and proliferation associated indices (PCNA, MIB1)
    N Zagorianakou
    Department of Pathology, Medical School, University of Ioannina, Greece
    Eur J Gynaecol Oncol 24:299-304. 2003
    ..This expression could be under hormonal control and does not seem to be correlated with other conventional or possible prognostic parameters...
  56. ncbi Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and progression
    E Ioachim
    Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Eur J Cancer 38:2362-70. 2002
    ..In addition, overexpression of stromal TN and FN seems to have negative prognostic value in breast cancer patients...
  57. ncbi Hypoxia and activated VEGF/receptor pathway in multiple myeloma
    Alexandra Giatromanolaki
    Department of Pathology, Democritus University of Thrace, P O Box 12, Alexandroupolis 68100, Greece
    Anticancer Res 30:2831-6. 2010
    ..Intensified angiogenic pathways are associated with poor prognosis and resistance of multiple myeloma (MM) cells to therapy. The links of the VEGF pathway with the hypoxia inducible factor (HIF) expression in MM are herein investigated...
  58. ncbi DCIS histopathology from a historical perspective
    A C Goussia
    Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece
    Eur J Gynaecol Oncol 27:282-5. 2006
    ..Historically, there has been some confusion regarding the definition of DCIS and the terminology associated with the histological types of DCIS. In this review, DCIS histopathology from a historical point of view is presented...
  59. ncbi Concurrent development of spontaneous pyomyositis due to Staphylococcus epidermidis and Kikuchi-Fujimoto disease
    Georgios Kalambokis
    The 1st Division of Internal Medicine, University Hospital, Ioannina, Greece
    Intern Med 47:2139-43. 2008
    ..We report a patient who developed spontaneous pyomyositis caused by S. epidermidis concurrently with KFD, and discuss the possibility of S. epidermidis infection being the stimulant of KFD...
  60. ncbi The role of apoptosis in the pathophysiology of Acute Respiratory Distress Syndrome (ARDS): an up-to-date cell-specific review
    Vasiliki Galani
    Department of Anatomy, Histology and Embryology, Medical School, University of Ioannina, Ioannina, Greece
    Pathol Res Pract 206:145-50. 2010
    ....
  61. ncbi Serum levels, and bone marrow immunohistochemical expression of, vascular endothelial growth factor in patients with chronic myeloproliferative diseases
    Katerina Panteli
    Department of Hematology, Medical Faculty, University of Ioannina, Ioannina, Greece
    Hematology 12:481-6. 2007
    ..001). The results of the present study suggest that, VEGF is a major angiogenetic factor in patients with cMPDs and contributes to the pathogenesis of these diseases...
  62. ncbi Diffuse large B-cell lymphomas with germinal center B-cell-like differentiation immunophenotypic profile are associated with high apoptotic index, high expression of the proapoptotic proteins bax, bak and bid and low expression of the antiapoptotic protei
    Maria Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece
    Mod Pathol 17:847-56. 2004
    ....
  63. ncbi The presence of proprioceptive mechanoreceptors in the remnants of the ruptured ACL as a possible source of re-innervation of the ACL autograft
    A D Georgoulis
    Department of Orthopaedic Surgery, Medical School, University of Ioannina, Ioannina 45110, Greece
    Knee Surg Sports Traumatol Arthrosc 9:364-8. 2001
    ..If we accept that restoration of proprioception is the result of reinnervation of the ACL, leaving the ACL remnants as a source, if this is surgically possible without risk of Cyclop's lesion, may be of potential benefit to the patient...
  64. ncbi Expression of cyclin D3 and cyclin E and identification of distinct clusters of proliferation and apoptosis in diffuse large B-cell lymphomas
    M Bai
    Department of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece
    Histol Histopathol 18:449-57. 2003
    ..The identification of distinct clusters with respect to the proliferation and the apoptosis status indicates that groups with distinct cellular kinetic properties can be defined in the histological group of DLBCL...
  65. ncbi Immunohistochemical expression of the p53, mdm2, p21/Waf-1, Rb, p16, Ki67, cyclin D1, cyclin A and cyclin B1 proteins and apoptotic index in T-cell lymphomas
    P Kanavaros
    Department of Histology, University of Thessallia, Greece
    Histol Histopathol 16:377-86. 2001
    ..These findings suggest that different pathogenetic routes may function in some TCL, involving either the p53 or, less frequently, the Rb pathways...
  66. ncbi Expression of Bax protein in gastric carcinomas. A clinicopathological and immunohistochemical study
    G K Anagnostopoulos
    Mitera General Hospital, Athens, Greece
    Acta Gastroenterol Belg 70:285-9. 2007
    ..Our aim was to immunohistochemically study Bax protein expression in gastric carcinomas and correlate its expression with clinicopathological parameters and prognosis...
  67. ncbi Immunohistochemical expression of p53, p21/waf1, rb, p16, cyclin D1, p27, Ki67, cyclin A, cyclin B1, bcl2, bax and bak proteins and apoptotic index in normal thymus
    P Kanavaros
    Department of Histology and Anatomy, University of Thessalia, Athens
    Histol Histopathol 16:1005-12. 2001
    ..The expressions of Bax and bak were more widespread in both the medulla and cortex, suggesting that these proteins play a broader role than bcl2 in the regulation of thymic apoptosis...
  68. ncbi Expression of dysadherin and E-cadherin in trophoblastic tissue in normal and abnormal pregnancies
    A Batistatou
    Placenta 28:590-2. 2007
  69. ncbi hMSH2 is the most commonly mutated MMR gene in a cohort of Greek HNPCC patients
    A Apessos
    Molecular Biology Research Center HYGEIA Antonis Papayiannis, Kifissias Ave and Erythrou Stavrou 4 Str, 15123 Maroussi, Athens, Greece
    Br J Cancer 92:396-404. 2005
    ..Finally, a number of novel benign variations were observed in both genes. This is the first report of HNPCC analysis in the Greek population, further underscoring the differences observed in the various geographic populations...
  70. ncbi Screening transvaginal uterine ultrasonography for identifying endometrial pathology in postmenopausal women
    E Paraskevaidis
    Department of Obstetrics and Gynecology and Ioannina University Hospital, Greece
    Anticancer Res 22:2517-20. 2002
    ..However, well-designed studies should be conducted, completed, analysed and validated before a mass-screening program using TVS is implemented...
  71. ncbi Angiogenesis in chronic myeloproliferative diseases detected by CD34 expression
    K Panteli
    Department of Hematology, University Hospital of Ioannina, Ioannina, Greece
    Eur J Haematol 72:410-5. 2004
    ..However, definitive conclusions regarding the prognostic value of increased angiogenesis may require additional follow-up and a larger group of patients...
  72. ncbi Clinical correlation of bone marrow microvessel density in essential thrombocythemia
    K Panteli
    Department of Hematology, University Hospital of Ioannina, Ioannina, Greece
    Acta Haematol 114:99-103. 2005
    ..These preliminary findings suggest that angiogenesis has no prognostic value in patients with ET...