Research Topics
Species | P G BagosSummaryAffiliation: University of Athens Country: Greece Publications
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Detail Information
Publications
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov ModelsNikolaos G Sgourakis
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 157 01, Greece
BMC Bioinformatics 6:104. 2005..The method predicts the coupling preferences of GPCRs to Gs, Gi/o and Gq/11, but not G12/13 subfamilies...- A database for G proteins and their interaction with GPCRsAntigoni L Elefsinioti
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 157 01, Greece
BMC Bioinformatics 5:208. 2004.... 
No evidence for association of CTLA-4 gene polymorphisms with the risk of developing multiple sclerosis: a meta-analysisPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens, Greece
Mult Scler 13:156-68. 2007....- Chlamydia pneumoniae infection and the risk of multiple sclerosis: a meta-analysisP G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens, 15701, Greece
Mult Scler 12:397-411. 2006..Even though the presence of Cpn is clearly more likely in MS patients, these findings are insufficient to establish an etiologic relation... 
Prediction of signal peptides in archaeaP G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 15701, Greece
Protein Eng Des Sel 22:27-35. 2009..The method, PRED-SIGNAL, and the results are freely available for academic users at http://bioinformatics.biol.uoa.gr/PRED-SIGNAL/ and we anticipate that it will be a valuable tool for the computational analysis of archaeal genomes...- How many 3D structures do we need to train a predictor?Pantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 15701, Greece
Genomics Proteomics Bioinformatics 7:128-37. 2009..Therefore, we should concentrate our efforts on utilizing new techniques for the development of even better scoring predictors... - Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteinsPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 157 01, Greece
BMC Bioinformatics 7:189. 2006..However, no clear and formal explanation of the algorithms that retains the probabilistic interpretation of the models has been presented so far in the literature... - The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14,094 cases and 17,760 controlsPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens, Greece
J Hypertens 25:487-500. 2007..In an effort to clarify earlier inconclusive results, we performed a meta-analysis of population-based case-control genetic association studies... - Evaluation of methods for predicting the topology of beta-barrel outer membrane proteins and a consensus prediction methodPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 15701, Greece
BMC Bioinformatics 6:7. 2005..Also, we describe, for the first time, an effective way to combine the individual predictors, at will, to a single consensus prediction method... - PRED-TMBB: a web server for predicting the topology of beta-barrel outer membrane proteinsPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 15701, Greece
Nucleic Acids Res 32:W400-4. 2004.... - A Hidden Markov Model method, capable of predicting and discriminating beta-barrel outer membrane proteinsPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 15701, Greece
BMC Bioinformatics 5:29. 2004..The model is trained in a discriminative manner, aiming at maximizing the probability of correct predictions rather than the likelihood of the sequences... - PRED-GPCR: GPCR recognition and family classification serverP K Papasaikas
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece
Nucleic Acids Res 32:W380-2. 2004..The server returns all single-motif matches along with the combined results for the corresponding families. The service is available online since October 2003 at http://bioinformatics.biol.uoa.gr/PRED-GPCR... - Apolipoprotein E polymorphisms and type 2 diabetes: a meta-analysis of 30 studies including 5423 cases and 8197 controlsP G Anthopoulos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Greece
Mol Genet Metab 100:283-91. 2010..Further studies are needed in order to elucidate the metabolic mechanism of this association as well as to study its effects on larger populations... - The association between apolipoprotein E gene polymorphisms and essential hypertension: a meta-analysis of 45 studies including 13,940 cases and 16, 364 controlsS Stoumpos
Department of Cell Biology and Biophysics, University of Athens, Athens, Greece
J Hum Hypertens 27:245-55. 2013..Further studies are needed in order to fully address questions about the etiological mechanism of the particular association, as well as to study the effect in populations of African descent... - Cytokine gene polymorphisms in multiple sclerosis: a meta-analysis of 45 studies including 7379 cases and 8131 controlsG K Nikolopoulos
Hellenic Centre for Diseases Control and Prevention, Athens, Greece
Eur J Neurol 18:944-51. 2011..Within its limitations, the current literature-based meta-analysis does not indicate that specific polymorphic variations of genes encoding pro-inflammatory and anti-inflammatory cytokines affect susceptibility to multiple sclerosis... - A novel method for GPCR recognition and family classification from sequence alone using signatures derived from profile hidden Markov modelsP K Papasaikas
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece
SAR QSAR Environ Res 14:413-20. 2003..A web-based version of the application is freely available at URL: http:/bioinformatics.biol.uoa.gr/PRED-GPCR... - beta-Barrel transmembrane proteins: Geometric modelling, detection of transmembrane region, and structural propertiesIoannis K Valavanis
Faculty of Informatics and Telecommunications, University of Athens, Panepistimiopolis, Athens 15784, Greece
Comput Biol Chem 30:416-24. 2006..In addition, we quantify the abundance of all amino acids and the average hydrophobicity for external and internal beta-stranded residues along the axis of beta-barrel, thus confirming and extending other researchers' results... - TMRPres2D: high quality visual representation of transmembrane protein modelsIoannis C Spyropoulos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece
Bioinformatics 20:3258-60. 2004..Several important biological and physical sequence attributes can be embedded in the graphical representation... - Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networksNikolaos G Sgourakis
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Greece
Bioinformatics 21:4101-6. 2005..AVAILABILITY: A webserver for academic users is available at http://bioinformatics.biol.uoa.gr/PRED-COUPLE2.. - PredSL: a tool for the N-terminal sequence-based prediction of protein subcellular localizationEvangelia I Petsalaki
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 15701, Greece
Genomics Proteomics Bioinformatics 4:48-55. 2006..Furthermore, PredSL is the only method capable for the prediction of these subcellular localizations that is available as a stand-alone application through the URL:http://bioinformatics.biol.uoa.gr/PredSL/... - Prediction of cell wall sorting signals in gram-positive bacteria with a hidden markov model: application to complete genomesZoi I Litou
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 15701, Greece
J Bioinform Comput Biol 6:387-401. 2008..The prediction tool, the database with the proteins identified in the genomes, and supplementary material are available online at http://bioinformatics.biol.uoa.gr/CW-PRED/... - gpDB: a database of GPCRs, G-proteins, effectors and their interactionsMargarita C Theodoropoulou
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 157 01, Greece
Bioinformatics 24:1471-2. 2008..AVAILABILITY: http://bioinformatics.biol.uoa.gr/gpDB CONTACT: shamodr@biol.uoa.gr SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online... - Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: a meta-analysisArgirios E Tsantes
Laboratory of Hematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Athens, Greece
Blood Coagul Fibrinolysis 18:497-504. 2007..The effect of this genotype on risk of ischemic stroke in acute stressful diseases and the role of cohort studies in genetic epidemiology, however, warrant further investigation... - Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis. A meta-analysisArgirios E Tsantes
Laboratory of Hematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Athens, Greece
Thromb Haemost 97:907-13. 2007..Recommendation for detection of this polymorphism in evaluating thrombophilia in such patients might be considered... - Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: a meta-analysisArgirios E Tsantes
Laboratory of Hematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Athens, Greece
Int J Cardiol 118:189-96. 2007..The importance of the GPla gene C807T polymorphism as a genetic risk factor for coronary artery disease (CAD) remains controversial. To assess this association, we performed a meta-analysis of published data... - Integrin, alpha 2 gene C807T polymorphism and risk of ischemic stroke: a meta-analysisGeorgios K Nikolopoulos
Hellenic Center for Disease Control and Prevention, Athens, Greece
Thromb Res 119:501-10. 2007..However, the research findings remain controversial... - A method for meta-analysis of case-control genetic association studies using logistic regressionPantelis G Bagos
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Greece
Stat Appl Genet Mol Biol 6:Article17. 2007..A STATA command performing all the available computations is available at http://bioinformatics.biol.uoa.gr/~pbagos/metagen/...