Dimitrros Alexopoulos

Summary

Affiliation: University of Patras
Country: Greece

Publications

  1. ncbi Coronary artery calcium by digital cinefluoroscopy in patients with pain suggestive of an acute coronary syndrome
    Dimitrros Alexopoulos
    Department of Medicine, Division of Cardiology, University of Patras Medical School, Patras, Greece
    Clin Cardiol 28:81-4. 2005
  2. ncbi Intrinsic platelet reactivity and thrombus burden in patients with ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece Electronic address
    Thromb Res 131:333-7. 2013
  3. ncbi P2Y12 inhibitors adjunctive to primary PCI therapy in STEMI: fighting against the activated platelets
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 163:249-55. 2013
  4. ncbi Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Greece
    Circ Cardiovasc Interv 5:797-804. 2012
  5. ncbi Pharmacodynamic effect of prasugrel 5 mg vs clopidogrel 150 mg in elderly patients with high on-clopidogrel platelet reactivity
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Am Heart J 165:73-9. 2013
  6. ncbi Thrombus extraction catheters vs. angiojet rheolytic thrombectomy in thrombotic lesions/SV grafts
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26504, Greece
    Curr Cardiol Rev 8:202-8. 2012
  7. ncbi Predictors of high on-treatment platelet reactivity early after clopidogrel loading in ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Circ J 76:2183-7. 2012
  8. ncbi Prasugrel versus high dose clopidogrel to overcome early high on clopidogrel platelet reactivity in patients with ST elevation myocardial infarction
    D Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, 26500, Patras, Greece
    Cardiovasc Drugs Ther 26:393-400. 2012
  9. ncbi Prediction of clopidogrel efficacy and safety: phenotyping and/or genotyping?
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, 26500 Patras, Greece
    Expert Rev Hematol 5:377-80. 2012
  10. ncbi Ticagrelor versus prasugrel in acute coronary syndrome patients with high on-clopidogrel platelet reactivity following percutaneous coronary intervention: a pharmacodynamic study
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    J Am Coll Cardiol 60:193-9. 2012

Detail Information

Publications21

  1. ncbi Coronary artery calcium by digital cinefluoroscopy in patients with pain suggestive of an acute coronary syndrome
    Dimitrros Alexopoulos
    Department of Medicine, Division of Cardiology, University of Patras Medical School, Patras, Greece
    Clin Cardiol 28:81-4. 2005
    ..Detection of coronary calcium may be a useful noninvasive approach for detecting coronary artery disease (CAD) in subjects presenting to the emergency department with chest pain...
  2. ncbi Intrinsic platelet reactivity and thrombus burden in patients with ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece Electronic address
    Thromb Res 131:333-7. 2013
    ..We aimed to evaluate the predictive accuracy of intrinsic platelet reactivity for intracoronary thrombus burden in P2Y12 inhibitor- naïve STEMI patients...
  3. ncbi P2Y12 inhibitors adjunctive to primary PCI therapy in STEMI: fighting against the activated platelets
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 163:249-55. 2013
    ..The efficacy and safety issues with the P2Y12 inhibitor use in STEMI and the possible role of phenotyping and/or genotyping for appropriate agent selection are discussed and several clinically important unanswered questions are raised...
  4. ncbi Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Greece
    Circ Cardiovasc Interv 5:797-804. 2012
    ..Ticagrelor and prasugrel provide stronger platelet inhibition compared with clopidogrel. Direct pharmacodynamic comparison between them has not yet been reported in ST-segment-elevation myocardial infarction patients...
  5. ncbi Pharmacodynamic effect of prasugrel 5 mg vs clopidogrel 150 mg in elderly patients with high on-clopidogrel platelet reactivity
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Am Heart J 165:73-9. 2013
    ..We aimed to test the hypothesis that in elderly patients exhibiting HPR after standard treatment with clopidogrel, prasugrel-reduced dose (5 mg) could be more effective than high-dose (150 mg) clopidogrel...
  6. ncbi Thrombus extraction catheters vs. angiojet rheolytic thrombectomy in thrombotic lesions/SV grafts
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26504, Greece
    Curr Cardiol Rev 8:202-8. 2012
    ....
  7. ncbi Predictors of high on-treatment platelet reactivity early after clopidogrel loading in ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Circ J 76:2183-7. 2012
    ..Methods and..
  8. ncbi Prasugrel versus high dose clopidogrel to overcome early high on clopidogrel platelet reactivity in patients with ST elevation myocardial infarction
    D Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, 26500, Patras, Greece
    Cardiovasc Drugs Ther 26:393-400. 2012
    ..If high on-treatment platelet reactivity (HTPR) is present, prasugrel reloading and subsequent maintenance dose (MD), might offer faster and stronger platelet inhibition than high clopidogrel MD...
  9. ncbi Prediction of clopidogrel efficacy and safety: phenotyping and/or genotyping?
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, 26500 Patras, Greece
    Expert Rev Hematol 5:377-80. 2012
    ..The authors recognize that it is premature to recommend any assay to guide the antiplatelet treatment in routine clinical practice. However, the need for properly powered randomized trials to address this issue is emphasized...
  10. ncbi Ticagrelor versus prasugrel in acute coronary syndrome patients with high on-clopidogrel platelet reactivity following percutaneous coronary intervention: a pharmacodynamic study
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    J Am Coll Cardiol 60:193-9. 2012
    ..The study aimed to compare the antiplatelet action of ticagrelor with prasugrel in acute coronary syndrome (ACS) patients with high on-treatment platelet reactivity (HTPR) while on clopidogrel after percutaneous coronary intervention (PCI)...
  11. ncbi Coronary artery calcium detection using flat panel digital cinefluoroscopy: comparison to coronary artery calcium score assessed with multiple detector computerized tomography
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 158:370-5. 2012
    ..The diagnostic accuracy of flat panel digital detector (FPDD) cinefluoroscopy for coronary artery calcium (CAC) detection, compared to multiple detector computed tomography (MDCT), is not known...
  12. ncbi Prasugrel resistance: fact or fiction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rio, Patras, Greece
    Platelets 23:83-90. 2012
    ..However, cases of inadequate platelet inhibition or of the so-called 'resistance' to prasugrel have been occasionally reported. The focus of this review is prasugrel resistance prevalence, mechanisms and potential clinical implications...
  13. ncbi A successfully thrombolysed acute inferior myocardial infarction due to type A aortic dissection with lethal consequences: the importance of early cardiac echocardiography
    Grigorios Tsigkas
    Department of Cardiology, Patras University School of Medicine, Patras, Greece
    J Cardiothorac Surg 6:101. 2011
    ..Prognostic implications of early diagnosis applying transthoracic echocardiography (TTE) are described...
  14. ncbi Heart echinococcus cyst as an incidental finding: early detection might be life-saving
    Grigorios Tsigkas
    Department of Cardiology, Patras University School of Medicine, Patras, Greece
    J Cardiothorac Surg 5:124. 2010
    ..Surgical excision was performed and the patient had an uneventful recovery and follow up at six and twelve months...
  15. ncbi Prasugrel overcomes high on-clopidogrel platelet reactivity in chronic coronary artery disease patients more effectively than high dose (150 mg) clopidogrel
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital Rio, Greece
    Am Heart J 162:733-9. 2011
    ..Strategies to optimize platelet inhibition in such patients are not clear...
  16. ncbi Prevalence of contraindications and conditions for precaution for prasugrel administration in a real world acute coronary syndrome population
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rio, Patras, Greece
    J Thromb Thrombolysis 32:328-33. 2011
    ..In a real world ACS population a relatively high proportion of patients have a potential contraindication for prasugrel administration or necessitate special attention for its use...
  17. ncbi Simultaneous drug-eluting and bare-metal stent implantation: long-term clinical outcome and findings of clinically indicated coronary angiography
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rio, Patras, Greece
    Clin Cardiol 34:317-21. 2011
    ..Simultaneous drug-eluting stent (DES) and bare-metal stent (BMS) implantation is occasionally employed in clinical practice, but its long-term clinical and angiographic outcome is not clear...
  18. ncbi Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: the importance of CYP2C19*2 genotyping
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece
    JACC Cardiovasc Interv 4:403-10. 2011
    ....
  19. ncbi Acute myocardial infarction late following stent implantation: Incidence, mechanisms and clinical presentation
    Dimitrios Alexopoulos
    Patras University Hospital, Cardiology Department, Rion 26500, Patras, Greece
    Int J Cardiol 152:295-301. 2011
    ..Angiographic follow-up and intracoronary imaging seem the most appropriate methods to define the exact pathophysiologic mechanism responsible for the AMI post stenting...
  20. ncbi Clopidogrel pretreatment in PCI: absolute requirement or obsolete myth?
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 146:305-10. 2011
    ..Several uncertain aspects are discussed...
  21. ncbi Antiplatelet effects of prasugrel vs. double clopidogrel in patients on hemodialysis and with high on-treatment platelet reactivity
    D Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece
    J Thromb Haemost 9:2379-85. 2011
    ..High on-treatment platelet reactivity (HTPR) is frequent in patients on hemodialysis (HD) receiving clopidrogel...