Dimitrros Alexopoulos

Summary

Affiliation: University of Patras
Country: Greece

Publications

  1. ncbi request reprint Coronary artery calcium by digital cinefluoroscopy in patients with pain suggestive of an acute coronary syndrome
    Dimitrros Alexopoulos
    Department of Medicine, Division of Cardiology, University of Patras Medical School, Patras, Greece
    Clin Cardiol 28:81-4. 2005
  2. pmc First-line treatment patterns and lipid target levels attainment in very high cardiovascular risk outpatients
    Ioanna Xanthopoulou
    From the Department of Cardiology, Patras University Hospital, Patras, Rion 26500, Greece
    Lipids Health Dis 12:170. 2013
  3. doi request reprint In-hospital switching of oral P2Y12 inhibitor treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention: prevalence, predictors and short-term outcome
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece Electronic address
    Am Heart J 167:68-76.e2. 2014
  4. doi request reprint Implementation of contemporary oral antiplatelet treatment guidelines in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a report from the GReek AntiPlatelet rEgistry (GRAPE)
    Dimitrios Alexopoulos
    Patras University Hospital, Department of Cardiology, Patras, Greece Electronic address
    Int J Cardiol 168:5329-35. 2013
  5. doi request reprint Differential effect of ticagrelor versus prasugrel on coronary blood flow velocity in patients with non-ST-elevation acute coronary syndrome undergoing percutaneous coronary intervention: an exploratory study
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Circ Cardiovasc Interv 6:277-83. 2013
  6. ncbi request reprint Factors affecting residual platelet aggregation in prasugrel treated patients
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26500, Greece
    Curr Pharm Des 19:5121-6. 2013
  7. pmc Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with diabetes
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Diabetes Care 36:2211-6. 2013
  8. doi request reprint In the search of coronary calcium
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece
    Int J Cardiol 167:310-7. 2013
  9. doi request reprint Intrinsic platelet reactivity and thrombus burden in patients with ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Thromb Res 131:333-7. 2013
  10. doi request reprint Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Greece
    Circ Cardiovasc Interv 5:797-804. 2012

Detail Information

Publications28

  1. ncbi request reprint Coronary artery calcium by digital cinefluoroscopy in patients with pain suggestive of an acute coronary syndrome
    Dimitrros Alexopoulos
    Department of Medicine, Division of Cardiology, University of Patras Medical School, Patras, Greece
    Clin Cardiol 28:81-4. 2005
    ..Detection of coronary calcium may be a useful noninvasive approach for detecting coronary artery disease (CAD) in subjects presenting to the emergency department with chest pain...
  2. pmc First-line treatment patterns and lipid target levels attainment in very high cardiovascular risk outpatients
    Ioanna Xanthopoulou
    From the Department of Cardiology, Patras University Hospital, Patras, Rion 26500, Greece
    Lipids Health Dis 12:170. 2013
    ..We aimed to investigate lipid treatment patterns, rates and predictors of lipid targets attainment, in such outpatients in an urban area of Greece...
  3. doi request reprint In-hospital switching of oral P2Y12 inhibitor treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention: prevalence, predictors and short-term outcome
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece Electronic address
    Am Heart J 167:68-76.e2. 2014
    ....
  4. doi request reprint Implementation of contemporary oral antiplatelet treatment guidelines in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a report from the GReek AntiPlatelet rEgistry (GRAPE)
    Dimitrios Alexopoulos
    Patras University Hospital, Department of Cardiology, Patras, Greece Electronic address
    Int J Cardiol 168:5329-35. 2013
    ..Few data exist about the implementation of contemporary oral antiplatelet treatment guidelines in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI)...
  5. doi request reprint Differential effect of ticagrelor versus prasugrel on coronary blood flow velocity in patients with non-ST-elevation acute coronary syndrome undergoing percutaneous coronary intervention: an exploratory study
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Circ Cardiovasc Interv 6:277-83. 2013
    ..We aimed to compare the effect of maintenance dose of ticagrelor versus prasugrel on coronary blood flow velocity (CBFV) during increasing doses of intravenously administered adenosine...
  6. ncbi request reprint Factors affecting residual platelet aggregation in prasugrel treated patients
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26500, Greece
    Curr Pharm Des 19:5121-6. 2013
    ..A high pre- treatment PR is associated with HPR, while a low pre-treatment PR and prasugrel loading predict HPI...
  7. pmc Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with diabetes
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Diabetes Care 36:2211-6. 2013
    ..We aimed to compare the pharmacodynamic action of ticagrelor versus prasugrel...
  8. doi request reprint In the search of coronary calcium
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece
    Int J Cardiol 167:310-7. 2013
    ..Further evolution and refinement of CAC detection methods is expected to lead to their more widespread application and even greater usefulness into clinical practice...
  9. doi request reprint Intrinsic platelet reactivity and thrombus burden in patients with ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Thromb Res 131:333-7. 2013
    ..We aimed to evaluate the predictive accuracy of intrinsic platelet reactivity for intracoronary thrombus burden in P2Y12 inhibitor- naïve STEMI patients...
  10. doi request reprint Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Greece
    Circ Cardiovasc Interv 5:797-804. 2012
    ..Ticagrelor and prasugrel provide stronger platelet inhibition compared with clopidogrel. Direct pharmacodynamic comparison between them has not yet been reported in ST-segment-elevation myocardial infarction patients...
  11. doi request reprint P2Y12 inhibitors adjunctive to primary PCI therapy in STEMI: fighting against the activated platelets
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 163:249-55. 2013
    ..The efficacy and safety issues with the P2Y12 inhibitor use in STEMI and the possible role of phenotyping and/or genotyping for appropriate agent selection are discussed and several clinically important unanswered questions are raised...
  12. doi request reprint Pharmacodynamic effect of prasugrel 5 mg vs clopidogrel 150 mg in elderly patients with high on-clopidogrel platelet reactivity
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Am Heart J 165:73-9. 2013
    ..We aimed to test the hypothesis that in elderly patients exhibiting HPR after standard treatment with clopidogrel, prasugrel-reduced dose (5 mg) could be more effective than high-dose (150 mg) clopidogrel...
  13. pmc Thrombus extraction catheters vs. angiojet rheolytic thrombectomy in thrombotic lesions/SV grafts
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26504, Greece
    Curr Cardiol Rev 8:202-8. 2012
    ....
  14. ncbi request reprint Predictors of high on-treatment platelet reactivity early after clopidogrel loading in ST-elevation myocardial infarction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    Circ J 76:2183-7. 2012
    ..Methods and..
  15. doi request reprint Prasugrel versus high dose clopidogrel to overcome early high on clopidogrel platelet reactivity in patients with ST elevation myocardial infarction
    D Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, 26500, Patras, Greece
    Cardiovasc Drugs Ther 26:393-400. 2012
    ..If high on-treatment platelet reactivity (HTPR) is present, prasugrel reloading and subsequent maintenance dose (MD), might offer faster and stronger platelet inhibition than high clopidogrel MD...
  16. ncbi request reprint Prediction of clopidogrel efficacy and safety: phenotyping and/or genotyping?
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, 26500 Patras, Greece
    Expert Rev Hematol 5:377-80. 2012
    ..The authors recognize that it is premature to recommend any assay to guide the antiplatelet treatment in routine clinical practice. However, the need for properly powered randomized trials to address this issue is emphasized...
  17. doi request reprint Ticagrelor versus prasugrel in acute coronary syndrome patients with high on-clopidogrel platelet reactivity following percutaneous coronary intervention: a pharmacodynamic study
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion, Patras, Greece
    J Am Coll Cardiol 60:193-9. 2012
    ..The study aimed to compare the antiplatelet action of ticagrelor with prasugrel in acute coronary syndrome (ACS) patients with high on-treatment platelet reactivity (HTPR) while on clopidogrel after percutaneous coronary intervention (PCI)...
  18. doi request reprint Coronary artery calcium detection using flat panel digital cinefluoroscopy: comparison to coronary artery calcium score assessed with multiple detector computerized tomography
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 158:370-5. 2012
    ..The diagnostic accuracy of flat panel digital detector (FPDD) cinefluoroscopy for coronary artery calcium (CAC) detection, compared to multiple detector computed tomography (MDCT), is not known...
  19. doi request reprint Prasugrel resistance: fact or fiction
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rio, Patras, Greece
    Platelets 23:83-90. 2012
    ..However, cases of inadequate platelet inhibition or of the so-called 'resistance' to prasugrel have been occasionally reported. The focus of this review is prasugrel resistance prevalence, mechanisms and potential clinical implications...
  20. pmc A successfully thrombolysed acute inferior myocardial infarction due to type A aortic dissection with lethal consequences: the importance of early cardiac echocardiography
    Grigorios Tsigkas
    Department of Cardiology, Patras University School of Medicine, Patras, Greece
    J Cardiothorac Surg 6:101. 2011
    ..Prognostic implications of early diagnosis applying transthoracic echocardiography (TTE) are described...
  21. pmc Heart echinococcus cyst as an incidental finding: early detection might be life-saving
    Grigorios Tsigkas
    Department of Cardiology, Patras University School of Medicine, Patras, Greece
    J Cardiothorac Surg 5:124. 2010
    ..Surgical excision was performed and the patient had an uneventful recovery and follow up at six and twelve months...
  22. doi request reprint Clopidogrel pretreatment in PCI: absolute requirement or obsolete myth?
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rion 26500, Patras, Greece
    Int J Cardiol 146:305-10. 2011
    ..Several uncertain aspects are discussed...
  23. doi request reprint Acute myocardial infarction late following stent implantation: Incidence, mechanisms and clinical presentation
    Dimitrios Alexopoulos
    Patras University Hospital, Cardiology Department, Rion 26500, Patras, Greece
    Int J Cardiol 152:295-301. 2011
    ..Angiographic follow-up and intracoronary imaging seem the most appropriate methods to define the exact pathophysiologic mechanism responsible for the AMI post stenting...
  24. doi request reprint Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: the importance of CYP2C19*2 genotyping
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece
    JACC Cardiovasc Interv 4:403-10. 2011
    ....
  25. doi request reprint Prevalence of contraindications and conditions for precaution for prasugrel administration in a real world acute coronary syndrome population
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital, Rio, Patras, Greece
    J Thromb Thrombolysis 32:328-33. 2011
    ..In a real world ACS population a relatively high proportion of patients have a potential contraindication for prasugrel administration or necessitate special attention for its use...
  26. doi request reprint Simultaneous drug-eluting and bare-metal stent implantation: long-term clinical outcome and findings of clinically indicated coronary angiography
    Dimitrios Alexopoulos
    Cardiology Department, Patras University Hospital, Rio, Patras, Greece
    Clin Cardiol 34:317-21. 2011
    ..Simultaneous drug-eluting stent (DES) and bare-metal stent (BMS) implantation is occasionally employed in clinical practice, but its long-term clinical and angiographic outcome is not clear...
  27. doi request reprint Prasugrel overcomes high on-clopidogrel platelet reactivity in chronic coronary artery disease patients more effectively than high dose (150 mg) clopidogrel
    Dimitrios Alexopoulos
    Department of Cardiology, Patras University Hospital Rio, Greece
    Am Heart J 162:733-9. 2011
    ..Strategies to optimize platelet inhibition in such patients are not clear...
  28. doi request reprint Antiplatelet effects of prasugrel vs. double clopidogrel in patients on hemodialysis and with high on-treatment platelet reactivity
    D Alexopoulos
    Department of Cardiology, Patras University Hospital, Patras, Greece
    J Thromb Haemost 9:2379-85. 2011
    ..High on-treatment platelet reactivity (HTPR) is frequent in patients on hemodialysis (HD) receiving clopidrogel...