K P Letsas

Summary

Affiliation: Onassis Cardiac Surgery Center
Country: Greece

Publications

  1. ncbi request reprint Pathophysiology and management of syncope in Kearns-Sayre syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Am Heart Hosp J 4:301-2. 2006
  2. ncbi request reprint Electrocardiographic characteristics of premature ventricular contractions in subjects with type 1 pattern of Brugada syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece Electronic address
    J Electrocardiol 47:351-5. 2014
  3. pmc Current ablation strategies for persistent and long-standing persistent atrial fibrillation
    Konstantinos P Letsas
    Laboratory of Invasive Cardiac Electrophysiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    Cardiol Res Pract 2011:376969. 2011
  4. pmc Electrocardiographic and electrophysiologic characteristics of ventricular extrasystoles arising from the aortomitral continuity
    Konstantinos P Letsas
    Laboratory of Invasive Cardiac Electrophysiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    Cardiol Res Pract 2011:864964. 2011
  5. pmc Idiopathic ventricular tachycardia arising from the right ventricular apex
    Konstantinos P Letsas
    Second Department of Cardiology, Laboratory of Invasive Cardiac Electrophysiology, Evangelismos General Hospital of Athens, 10676, Athens, Greece
    Indian Pacing Electrophysiol J 13:80-3. 2013
  6. doi request reprint Sinus node disease in subjects with type 1 ECG pattern of Brugada syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    J Cardiol 61:227-31. 2013
  7. doi request reprint The impact of body mass index on the efficacy and safety of catheter ablation of atrial fibrillation
    Konstantinos P Letsas
    Laboratory of Cardiac Electrophysiology, Evangelismos General Hospital of Athens, Athens, Greece
    Int J Cardiol 164:94-8. 2013
  8. doi request reprint Novel indexes of heterogeneity of ventricular repolarization in subjects with early repolarization pattern
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 45 47 Ipsilantou Street, 10676 Athens, Greece
    Europace 14:877-81. 2012
  9. doi request reprint Neurally mediated susceptibility in individuals with Brugada-type ECG pattern
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Pacing Clin Electrophysiol 31:418-21. 2008
  10. doi request reprint Tpeak-Tend interval and Tpeak-Tend/QT ratio as markers of ventricular tachycardia inducibility in subjects with Brugada ECG phenotype
    Konstantinos P Letsas
    Abteilung Rhythmologie, Herz Zentrum, Südring 15, 79189 Bad Krozingen, Germany
    Europace 12:271-4. 2010

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Pathophysiology and management of syncope in Kearns-Sayre syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Am Heart Hosp J 4:301-2. 2006
    ..Transthoracic echocardiography revealed normal wall motion of both ventricles and mitral valve prolapse without regurgitation. A permanent dual-chamber pacemaker was immediately implanted...
  2. ncbi request reprint Electrocardiographic characteristics of premature ventricular contractions in subjects with type 1 pattern of Brugada syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece Electronic address
    J Electrocardiol 47:351-5. 2014
    ..The ECG characteristics of premature ventricular contractions (PVCs) in subjects with Brugada syndrome (BrS) phenotype were investigated...
  3. pmc Current ablation strategies for persistent and long-standing persistent atrial fibrillation
    Konstantinos P Letsas
    Laboratory of Invasive Cardiac Electrophysiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    Cardiol Res Pract 2011:376969. 2011
    ..Up to now, no single strategy is uniformly effective in patients with persistent and long-standing persistent AF. The present study reviewed the efficacy of the current ablation strategies for persistent and long-standing persistent AF...
  4. pmc Electrocardiographic and electrophysiologic characteristics of ventricular extrasystoles arising from the aortomitral continuity
    Konstantinos P Letsas
    Laboratory of Invasive Cardiac Electrophysiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    Cardiol Res Pract 2011:864964. 2011
    ..The electrocardiographic and electrophysiologic characteristics of this arrhythmia are discussed...
  5. pmc Idiopathic ventricular tachycardia arising from the right ventricular apex
    Konstantinos P Letsas
    Second Department of Cardiology, Laboratory of Invasive Cardiac Electrophysiology, Evangelismos General Hospital of Athens, 10676, Athens, Greece
    Indian Pacing Electrophysiol J 13:80-3. 2013
    ..We present a rare case of idiopathic ventricular tachycardia arising from the right ventricular apex. The electrocardiographic and electrophysiological characteristics of this tachycardia are discussed...
  6. doi request reprint Sinus node disease in subjects with type 1 ECG pattern of Brugada syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    J Cardiol 61:227-31. 2013
    ..The present study investigated the incidence of SND in subjects with type 1 electrocardiogram (ECG) pattern of BS...
  7. doi request reprint The impact of body mass index on the efficacy and safety of catheter ablation of atrial fibrillation
    Konstantinos P Letsas
    Laboratory of Cardiac Electrophysiology, Evangelismos General Hospital of Athens, Athens, Greece
    Int J Cardiol 164:94-8. 2013
    ..Obesity is a well established risk factor for atrial fibrillation (AF) development. Our purpose was to determine the impact of body mass index (BMI) on the safety and efficacy of radiofrequency catheter ablation of AF...
  8. doi request reprint Novel indexes of heterogeneity of ventricular repolarization in subjects with early repolarization pattern
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 45 47 Ipsilantou Street, 10676 Athens, Greece
    Europace 14:877-81. 2012
    ..The present study investigated specific electrocardiographic (ECG) markers including Tpeak-Tend interval and (Tpeak-Tend)/QT ratio that reflect TDR in subjects with ER...
  9. doi request reprint Neurally mediated susceptibility in individuals with Brugada-type ECG pattern
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Pacing Clin Electrophysiol 31:418-21. 2008
    ..This study aimed to investigate the incidence of neurally mediated susceptibility in individuals with Brugada-type electrocardiogram (ECG) pattern...
  10. doi request reprint Tpeak-Tend interval and Tpeak-Tend/QT ratio as markers of ventricular tachycardia inducibility in subjects with Brugada ECG phenotype
    Konstantinos P Letsas
    Abteilung Rhythmologie, Herz Zentrum, Südring 15, 79189 Bad Krozingen, Germany
    Europace 12:271-4. 2010
    ..The present study investigated whether several ECG markers of ventricular repolarization are associated with ventricular tachycardia/fibrillation (VT/VF) inducibility in subjects with type 1 ECG pattern of Brugada syndrome (BS)...
  11. doi request reprint Clinical characteristics of patients with drug-induced QT interval prolongation and torsade de pointes: identification of risk factors
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Clin Res Cardiol 98:208-12. 2009
    ..Marked QTc interval prolongation should be considered of prognostic significance for TdP and cardiac arrest events...
  12. ncbi request reprint The natural history of arrhythmogenic right ventricular cardiomyopathy
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676, Athens, Greece
    Am Heart Hosp J 5:259-62. 2007
    ..Her medical history included recurrent episodes of syncope beginning at the age of 28. The natural history of the disease is discussed...
  13. ncbi request reprint Drug-induced long QT syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Hellenic J Cardiol 48:296-9. 2007
  14. doi request reprint Pre-ablative predictors of atrial fibrillation recurrence following pulmonary vein isolation: the potential role of inflammation
    Konstantinos P Letsas
    Arrhythmia Service, Herz Zentrum, Bad Krozingen, Germany
    Europace 11:158-63. 2009
    ....
  15. doi request reprint Prevalence of early repolarization pattern in inferolateral leads in patients with Brugada syndrome
    Konstantinos P Letsas
    Arrhythmia Service, Herz Zentrum, Bad Krozingen, Germany
    Heart Rhythm 5:1685-9. 2008
    ..Recent data have shown a high incidence of the early repolarization pattern confined in inferolateral leads in patients with idiopathic ventricular fibrillation...
  16. doi request reprint Predictors of atrial tachyarrhythmias in subjects with type 1 ECG pattern of Brugada syndrome
    Konstantinos P Letsas
    Arrhythmia Service, Herz Zentrum, Bad Krozingen, Germany
    Pacing Clin Electrophysiol 32:500-5. 2009
    ..The present study aimed to investigate whether various 12-lead electrocardiogram (ECG) and electrophysiological parameters may help to differentiate subjects with a high probability to develop ATs...
  17. ncbi request reprint Electrocardiographic differentiation of common type atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia via a concealed accessory pathway
    Konstantinos P Letsas
    Division of Rhythmology, Herz Zentrum, Bad Krozingen, Germany
    Acta Cardiol 65:171-6. 2010
    ....
  18. doi request reprint Epsilon-like waves and ventricular conduction abnormalities in subjects with type 1 ECG pattern of Brugada syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    Heart Rhythm 8:874-8. 2011
    ..Previous studies have demonstrated an overlap between the arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) and Brugada syndrome (BS). Conduction delay in the right ventricle has been demonstrated in both entities...
  19. doi request reprint Long-term prognosis of asymptomatic individuals with spontaneous or drug-induced type 1 electrocardiographic phenotype of Brugada syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    J Electrocardiol 44:346-9. 2011
    ..This study investigated the long-term prognosis of asymptomatic subjects with spontaneous or drug-induced type 1 ECG pattern of BS...
  20. ncbi request reprint Prevalence of Brugada sign in a Greek tertiary hospital population
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 45 47 Ipsilantou St, 10676 Athens, Greece
    Europace 9:1077-80. 2007
    ....
  21. ncbi request reprint Prevalence of paroxysmal atrial fibrillation in Brugada syndrome: a case series and a review of the literature
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital, Athens, Greece
    J Cardiovasc Med (Hagerstown) 8:803-6. 2007
    ..Both clinical entities are closely associated with changes in autonomic modulation and, particularly, with increased vagal tone...
  22. ncbi request reprint Enterovirus-induced fulminant myocarditis and hemophagocytic syndrome
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    J Infect 54:e75-7. 2007
    ..This is the first report that documents concomitant presentation of fulminant myocarditis and hemophagocytic syndrome due to enteroviral infection...
  23. ncbi request reprint Transcription factor-mediated proliferation and apoptosis in benign and malignant thyroid lesions
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    Pathol Int 55:694-702. 2005
    ..Furthermore, prothymosin alpha may promote cell survival through the Bcl2 anti-apoptotic pathway, while E2F-1-induced apoptosis via p53-independent pathways may be associated with transcriptional activation of bax pro-apoptotic gene...
  24. ncbi request reprint Fine-needle aspiration biopsy-RT-PCR expression analysis of prothymosin alpha and parathymosin in thyroid: novel proliferation markers?
    Konstantinos P Letsas
    Medical School of Ioannina, Greece
    Neoplasma 54:57-62. 2007
    ....
  25. ncbi request reprint Surfing on prothymosin alpha proliferation and anti-apoptotic properties
    K P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    Neoplasma 53:92-6. 2006
    ..The present review highlights on the proliferation and anti-apoptotic properties of prothymosin alpha and its possible role in cancer development...
  26. ncbi request reprint Fine needle aspiration biopsy-RT-PCR molecular analysis of thyroid nodules: a useful preoperative diagnostic tool
    K P Letsas
    Division of Endocrinology, Department of Medicine, University Hospital of Ioannina, Greece
    Minerva Endocrinol 31:179-82. 2006
    ..The parallel molecular and cytological analysis of FNABs may contribute to a more accurate diagnosis and, thus, to a more specific clinical management of thyroid nodules...
  27. ncbi request reprint Giant left atrium secondary to rheumatic mitral valve disease
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Am J Geriatr Cardiol 15:253-4. 2006
  28. doi request reprint Determinants of plasma NT-pro-BNP levels in patients with atrial fibrillation and preserved left ventricular ejection fraction
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece
    Clin Res Cardiol 98:101-6. 2009
    ..The present study aimed to investigate the clinical and echocardiographic determinants of plasma NT-pro-BNP levels in patients with atrial fibrillation (AF) and preserved left ventricular ejection fraction (LVEF)...
  29. doi request reprint Catheter ablation of recipient-to-donor atrioatrial conduction with Wenckebach-like phenomenon after orthotopic heart transplantation
    Konstantinos P Letsas
    Arrhythmia Service, Herz Zentrum, Bad Krozingen, Germany
    J Heart Lung Transplant 27:917-20. 2008
    ..Radio-frequency energy application resulted in immediate recipient-to-donor conduction block...
  30. ncbi request reprint QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone
    Stavros P Kounas
    Second Department of Cardiology, Evagelismos Hospital, Athens, Greece
    Pacing Clin Electrophysiol 28:472-3. 2005
    ..The case highlights a previously unknown drug interaction. The role of inhibition of cytochrome P-450 CYP3A4 is discussed...
  31. pmc Predictors of atrial fibrillation recurrence in patients with long-lasting atrial fibrillation
    Michalis Efremidis
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Can J Cardiol 25:e119-24. 2009
    ..Limited data are available on the predictors of atrial fibrillation (AF) recurrence in patients with chronic AF...
  32. ncbi request reprint Wide QRS complex supraventricular tachycardia with negative precordial concordance
    Loukas K Pappas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Am Heart Hosp J 7:67-8. 2009
    ..This case represents a rare exception to the rule that negative precordial QRS concordance is diagnostic of ventricular tachycardia...
  33. ncbi request reprint Excessive vagal response during left atrial ablation in a patient with paroxysmal atrial fibrillation
    Michalis Efremidis
    Second Department of Cardiology, Evangelismos General Hospital, Athens, Greece
    Hellenic J Cardiol 50:227-9. 2009
    ..During radiofrequency application around the left superior pulmonary vein, the patient exhibited an excessive vagal response with a sinus pause of 17 s...
  34. ncbi request reprint Ablation of atrial fibrillation in patients with heart failure: reversal of atrial and ventricular remodelling
    Michalis Efremidis
    Second Department of Cardiology, Evangelismos General Hospital, Greece
    Hellenic J Cardiol 49:19-25. 2008
    ..The management of patients with heart failure and atrial fibrillation (AF) is a medical challenge, especially in the case of patients in whom sinus rhythm or rate control cannot be achieved with optimal pharmaceutical treatment...
  35. ncbi request reprint Potential-guided versus anatomic-guided approach for slow pathway ablation of the common type atrioventricular nodal reentry tachycardia: a randomized study
    Michael Efremidis
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece
    Acta Cardiol 64:477-83. 2009
    ....
  36. ncbi request reprint ECG findings of acute myocardial infarction and atrioventricular block during a transseptal procedure for left atrial ablation
    Michalis Efremidis
    Second Department of Cardiology, Laboratory of Electrophysiology, Evaggelismos General Hospital of Athens, Greece
    Hellenic J Cardiol 49:284-7. 2008
    ..Coronary artery embolism following the transseptal procedure represents an alternative mechanism. The above mechanisms could also explain the atrioventricular block...
  37. doi request reprint Reversal of premature ventricular complex-induced cardiomyopathy following successful radiofrequency catheter ablation
    Michalis Efremidis
    Second Department of Cardiology, Evangelismos General Hospital of Athens, 25, 28th Octovriou st, 15235, 10676 Athens, Greece
    Europace 10:769-70. 2008
    ..Elimination of the left ventricular focus following radiofrequency catheter ablation resulted in reversal of cardiomyopathy...
  38. doi request reprint Adenosine sensitive focal atrial tachycardia originating from the non-coronary aortic cusp
    Reinhold Weber
    Abteilung Rhythmologie, Herz Zentrum, Südring 15, 79189 Bad Krozingen, Germany
    Europace 11:823-6. 2009
    ....
  39. ncbi request reprint Large left atrial myxoma presented as fever of unknown origin: a challenging diagnosis and a review of the literature
    Gerasimos Gavrielatos
    Second Department of Cardiology, Evangelismos General Hospital Athens, Greece
    Cardiovasc Pathol 16:365-7. 2007
    ..Herein, we describe the case of a 70-year-old patient with a long-lasting low-grade fever due to a large left atrial myxoma revealed during a transthoracic echocardiography...
  40. ncbi request reprint Uric acid elevation in atrial fibrillation
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    Hellenic J Cardiol 51:209-13. 2010
    ..Recently, atrial fibrillation (AF) has been associated with inflammation and oxidative stress. We therefore investigated the association between AF and uric acid levels...
  41. ncbi request reprint Brugada electrocardiographic pattern induced during febrile state with marked leukocytosis
    Gerasimos Gavrielatos
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    Pacing Clin Electrophysiol 30:135-6. 2007
    ..At a molecular level, sodium channels have been showed to be temperature dependent. Herein, we describe a case of Brugada electrocardiographic pattern unmasked during febrile state and marked leukocytosis...
  42. ncbi request reprint Anomalous origin of the entire coronary system with separate ostia within the right sinus of valsalva: a rare congenital anomaly and a review of the literature
    Gerasimos Gavrielatos
    Second Department of Cardiology, Interventional Unit, Evangelismos General Hospital, Athens, Greece
    Cardiology 107:209-12. 2007
    ..Congenital coronary artery malformations occur infrequently in the general population. In this report, we describe a rare case of anomalous origin of all three coronary arteries from separate ostia within the right coronary sinus...
  43. ncbi request reprint Drug-induced QT interval prolongation after ciprofloxacin administration in a patient receiving olanzapine
    Konstantinos P Letsas
    Int J Cardiol 109:273-4. 2006
    ..In the present case report, an elderly woman receiving a long-term medication with azathioprine, olanzapine and valsartan developed a marked QT interval prolongation after intravenous administration of ciprofloxacin...
  44. ncbi request reprint Exercise-induced second-degree atrioventricular block
    Loukas K Pappas
    Int J Cardiol 111:461-3. 2006
    ..A gap phenomenon involving a proximal and distal part of the AV node may be a likely explanation of paradoxical AV conduction in our case...
  45. ncbi request reprint Early repolarization syndrome: is it always benign?
    Konstantinos P Letsas
    Int J Cardiol 114:390-2. 2007
    ..We report the case of a 39-year-old male with a family history of sudden death and an electrocardiogram consistent with early repolarization syndrome. Diagnostic dilemmas are discussed...
  46. ncbi request reprint ST-segment elevation induced during the transseptal procedure for radiofrequency catheter ablation of atrial fibrillation
    Konstantinos P Letsas
    Int J Cardiol 114:e12-4. 2007
    ..Coronary artery embolism following the transseptal procedure represents a different underlying mechanism...
  47. ncbi request reprint QT interval prolongation and torsade de pointes associated with indapamide
    Konstantinos P Letsas
    Int J Cardiol 112:373-4. 2006
    ..The case of an acquired long QT and torsade de pointes ventricular tachycardia in a woman with systemic lupus erythematosus and hypertension receiving prednisolone and indapamide, respectively, is described in the present report...
  48. ncbi request reprint Giant left-ventricular pseudoaneurysm following silent myocardial infarction
    Dimitrios Evangelou
    Cardiology 105:137-8. 2006
  49. ncbi request reprint QT interval prolongation and Torsades de Pointes in a patient receiving zolpidem and amiodarone
    Konstantinos P Letsas
    Cardiology 105:146-7. 2006
  50. ncbi request reprint Swimming-triggered aborted sudden cardiac death in a patient with Andersen-Tawil syndrome
    Michalis Efremidis
    Int J Cardiol 112:e45-7. 2006
    ..To our knowledge, this is the first report of a swimming-triggered cardiac event in a patient with Andersen-Tawil syndrome...
  51. ncbi request reprint Secondary prevention of sudden cardiac death in coronary artery spasm: is implantable cardioverter defibrillator always efficient?
    Konstantinos P Letsas
    Int J Cardiol 117:141-3. 2007
    ..The efficacy of implantable cardioverter defibrillator in secondary prevention of sudden cardiac death due to coronary artery spasm is discussed...
  52. ncbi request reprint Sotalol unmasks susceptibility to drug-induced long QT syndrome and torsades de pointes
    Konstantinos P Letsas
    Int J Cardiol 124:366-7; author reply 368-9. 2008