Genovefa Kolovou

Summary

Affiliation: Onassis Cardiac Surgery Center
Country: Greece

Publications

  1. doi request reprint Postprandial lipaemia and vascular disease
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Opin Cardiol 28:446-51. 2013
  2. doi request reprint Cholesteryl ester transfer protein and ATP-binding cassette transporter A1 genotype alter the atorvastatin and simvastatin efficacy: time for genotype-guided therapy?
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 64:266-72. 2013
  3. pmc Sex-associated effect of CETP and LPL polymorphisms on postprandial lipids in familial hypercholesterolaemia
    Katherine K Anagnostopoulou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Lipids Health Dis 8:24. 2009
  4. ncbi request reprint Primary and secondary hypertriglyceridaemia
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Curr Drug Targets 10:336-43. 2009
  5. ncbi request reprint Apolipoprotein E gene polymorphism and obesity status in middle-aged men with coronary heart disease
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    In Vivo 23:33-9. 2009
  6. ncbi request reprint Apolipoprotein E gene polymorphism and gender
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens University Medical School, Athens, Greece
    Ann Clin Lab Sci 39:120-33. 2009
  7. doi request reprint Mortality after first myocardial infarction in Greek patients: a 4-year follow-up study
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 60:582-7. 2009
  8. doi request reprint Ideal lipid profile and genes for an extended life span
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Opin Cardiol 26:348-55. 2011
  9. ncbi request reprint Effects of estrogens on atherogenesis
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, Athens, Greece
    Curr Vasc Pharmacol 9:244-57. 2011
  10. ncbi request reprint Postprandial lipemia in children and adolescents
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, 17674 Athens, Greece
    Curr Vasc Pharmacol 9:318-20. 2011

Detail Information

Publications51

  1. doi request reprint Postprandial lipaemia and vascular disease
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Opin Cardiol 28:446-51. 2013
    ....
  2. doi request reprint Cholesteryl ester transfer protein and ATP-binding cassette transporter A1 genotype alter the atorvastatin and simvastatin efficacy: time for genotype-guided therapy?
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 64:266-72. 2013
    ..02 for all comparisons). The TaqIB and R219K (opposite to I405V) gene polymorphisms seem to modify the response to lipid-lowering therapy with simvastatin or atorvastatin treatment...
  3. pmc Sex-associated effect of CETP and LPL polymorphisms on postprandial lipids in familial hypercholesterolaemia
    Katherine K Anagnostopoulou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Lipids Health Dis 8:24. 2009
    ....
  4. ncbi request reprint Primary and secondary hypertriglyceridaemia
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Curr Drug Targets 10:336-43. 2009
    ..Also, hypertriglyceridaemia (TG >150 mg/dl; 1.7 mmol/l) is one of the diagnostic criteria of metabolic syndrome. Finally, several drugs may increase TG levels (e.g. chlorthalidone or beta-blockers)...
  5. ncbi request reprint Apolipoprotein E gene polymorphism and obesity status in middle-aged men with coronary heart disease
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    In Vivo 23:33-9. 2009
    ..Apolipoprotein (apo) E polymorphism has been associated with coronary heart disease (CHD) and obesity. We aimed to determine whether apoE polymorphism is related to CHD in patients with different body mass index (BMI)...
  6. ncbi request reprint Apolipoprotein E gene polymorphism and gender
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens University Medical School, Athens, Greece
    Ann Clin Lab Sci 39:120-33. 2009
    ..The studies cited here demonstrate a complex, multifactorial association between these factors, in need of further corroboration in greater population samples...
  7. doi request reprint Mortality after first myocardial infarction in Greek patients: a 4-year follow-up study
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 60:582-7. 2009
    ..Death associated with coronary heart disease (CHD) depends in part on the time since the myocardial infarction (MI) and modification of risk factors...
  8. doi request reprint Ideal lipid profile and genes for an extended life span
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Opin Cardiol 26:348-55. 2011
    ..Cholesterol levels in general rise with age and high cholesterol has been associated with extreme longevity. The relationship between lipids and cardiovascular events in the extreme elderly is unclear...
  9. ncbi request reprint Effects of estrogens on atherogenesis
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, Athens, Greece
    Curr Vasc Pharmacol 9:244-57. 2011
    ..Finally, hormone replacement therapy will be briefly described...
  10. ncbi request reprint Postprandial lipemia in children and adolescents
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, 17674 Athens, Greece
    Curr Vasc Pharmacol 9:318-20. 2011
    ..It is not clear if postprandial lipemia should be evaluated in children and adolescents. However, in special situations this may help determine the underlying lipid disorder. This review discusses the current status in this field...
  11. ncbi request reprint Definition of postprandial lipaemia
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, 17674 Athens, Greece
    Curr Vasc Pharmacol 9:292-301. 2011
    ..PPL is a complex syndrome characterized by non-fasting hypertriglyceridaemia that is associated with an increased risk of vascular events. This review considers the definition of PPL and the methodology for assessing this process...
  12. ncbi request reprint Assessment and clinical relevance of non-fasting and postprandial triglycerides: an expert panel statement
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, 17674 Athens, Greece
    Curr Vasc Pharmacol 9:258-70. 2011
    ..7). A higher and undesirable postprandial TG response could be treated by aggressive lifestyle modification (including nutritional supplementation) and/or TG lowering drugs like statins, fibrates and nicotinic acid...
  13. pmc The role of common variants of the cholesteryl ester transfer protein gene in left main coronary artery disease
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center 356, Sygrou Ave, 176 74 Athens, Greece
    Lipids Health Dis 10:156. 2011
    ..The cholesteryl ester transfer protein (CETP) has a central role in the lipid metabolism and therefore may alter the susceptibility to atherosclerosis...
  14. ncbi request reprint Therapeutic effects of fibrates in postprandial lipemia
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Cardiovasc Drugs 8:243-55. 2008
    ..Fibrates are well tolerated by patients and adverse effects have been reported rarely after their administration...
  15. doi request reprint Influence of aging and menopause on lipids and lipoproteins in women
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 59:54S-7S. 2008
    ..In this review, the current understanding of an influence of age and menopause on lipids and lipoproteins concentration in women will be analyzed...
  16. ncbi request reprint The prevalence of metabolic syndrome in various populations
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Med Sci 333:362-71. 2007
    ..This review also considers the impact of metabolic syndrome on cardiovascular disease...
  17. ncbi request reprint Gender influence on postprandial lipemia in heterozygotes for familial hypercholesterolemia
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Ann Clin Lab Sci 37:335-42. 2007
    ..In summary, hFH men have higher BMI, fasting TG level, and postprandial TG level, compared to age-matched premenopausal hFH women, which may partially explain the earlier onset of coronary heart disease in hFH men...
  18. ncbi request reprint Apolipoprotein E knockout models
    Genovefa Kolovou
    Onassis Cardiac Surgery Center, 356 Sygrou Ave 176 74 Athens, Greece
    Curr Pharm Des 14:338-51. 2008
    ..The current review considers lipid metabolism and inflammation as well as nutritional and pharmacological agents affecting atherosclerosis, using the apo E knock out mouse model...
  19. ncbi request reprint The effect of statins on postprandial lipemia
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Drug Targets 8:551-60. 2007
    ..Since abnormal postprandial lipemia is associated with pathological conditions, its treatment is relevant. This review considers the effect of statins on postprandial lipemia...
  20. doi request reprint Simvastatin: two decades in a circle
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Cardiovasc Ther 26:166-78. 2008
    ..In this review, we will present all these effects, as well as the beneficial effects on atherogenesis and the reduction in cardiovascular morbidity and mortality related to simvastatin...
  21. ncbi request reprint Apolipoprotein E polymorphism, age and coronary heart disease
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Ave, 176 74 Athens, Greece
    Ageing Res Rev 6:94-108. 2007
    ..If apo E polymorphism is an important genetic factor in the pathogenesis of atherosclerosis, it could affect the age of CHD onset. This review analyses the influence of apo E polymorphism on blood lipids and CHD in respect to age...
  22. ncbi request reprint Association between the TaqIB polymorphism in the cholesteryl ester transfer protein gene locus and postprandial plasma lipoprotein levels in heterozygotes for familial hypercholesterolemia
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Clin Chem Lab Med 45:1190-8. 2007
    ..We examined the influence of cholesteryl ester transfer protein TaqIB polymorphism on triglyceride (TG) response to an oral fat tolerance test (OFTT) in patients heterozygous for familial hypercholesterolemia (hFH)...
  23. pmc Association of gender, ABCA1 gene polymorphisms and lipid profile in Greek young nurses
    Vana Kolovou
    Molecular Immunology Laboratory, Onassis Cardiac Surgery Center Athens, Athens, Greece 2Thriassio General Hospital, Magoula, Attica, Greece
    Lipids Health Dis 11:62. 2012
    ..We analyzed SNPs in chromosome 9 such as rs2230806 (R219K) in the position 107620867, rs2230808 (R1587K) in the position 106602625 and rs4149313 (I883M) in the position 106626574 according to gender and lipid profile of Greek nurses...
  24. doi request reprint Efficacy of simvastatin or ezetimibe on tissue factor, von Willebrand's factor and C-reactive protein in patients with hypercholesterolaemia
    Peggy Kostakou
    1 st Cardiology Department, Onassis Cardiac Surgery Centre, 356, Sygrou Ave, 17674 Athens, Greece
    Arch Cardiovasc Dis 103:26-32. 2010
    ..Statins have favourable effects on lipid profiles, decrease total mortality and have many pleiotropic effects...
  25. pmc Myocardial inflammation in Duchenne Muscular Dystrophy as a precipitating factor for heart failure: a prospective study
    Sophie Mavrogeni
    A Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    BMC Neurol 10:33. 2010
    ..We evaluated the role of myocardial inflammation as a precipitating factor in the development of heart failure in DMD...
  26. doi request reprint Aging men and lipids
    Genovefa Kolovou
    Onassis Cardiac Surgery Center, Athens, Greece
    Am J Mens Health 5:152-65. 2011
    ..In aging men, this negative influence of androgens on the lipid profile is more pronounced. This review considers the influence of age on lipid metabolism in men...
  27. ncbi request reprint Pharmacogenetic study of cholesteryl ester transfer protein gene and simvastatin treatment in hypercholesterolaemic subjects
    Katherine Anagnostopoulou
    Onassis Cardiac Surgery Center, 1st Cardiology Department, 356 Sygrou Avenue, 176 74 Athens, Greece
    Expert Opin Pharmacother 8:2459-63. 2007
    ..To examine the effect of the I405V and TaqIB polymorphisms of cholesteryl ester transfer protein (CETP) on the lipid response after simvastatin treatment in 180 hypercholesterolaemic patients...
  28. ncbi request reprint Association of apolipoprotein E polymorphism with myocardial infarction in Greek patients with coronary artery disease
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Med Res Opin 18:118-24. 2002
    ..3% vs. 10.2%). In summary, the epsilon4 allele was not found to be associated with an increased risk for CAD or MI. In contrast, a negative association of the epsilon2 allele with Ml was observed among Greek patients with CAD...
  29. pmc Cholesteryl ester transfer protein gene and effectiveness of lipid lowering of atorvastatin
    Genovefa Kolovou
    1 Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Open Cardiovasc Med J 4:297-301. 2010
    ..CETP TaqIB or I405V polymorphisms seem to modify the lipid lowering response to atorvastatin treatment. This knowledge may help design more effective hypolipidaemic treatment...
  30. doi request reprint The frequency of 4 common gene polymorphisms in nonagenarians, centenarians, and average life span individuals
    Genovefa Kolovou
    1Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Angiology 65:210-5. 2014
    ..045). No differences in frequency of common NFkB and CETP genotypes between patients with exceptional longevity and middle-aged patients were observed. ..
  31. doi request reprint Cardiovascular magnetic resonance imaging in asymptomatic patients with connective tissue disease and recent onset left bundle branch block
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece Electronic address
    Int J Cardiol 171:82-7. 2014
    ..We hypothesized that cardiovascular magnetic resonance (CMR) may be of diagnostic value in CTDs with recent LBBB and normal echocardiogram...
  32. pmc ATP-binding cassette transporter A1 gene polymorphisms and serum lipid levels in young Greek nurses
    Vana Kolovou
    Molecular Immunology Laboratory, Onassis Cardiac Surgery Center Athens, Greece
    Lipids Health Dis 10:56. 2011
    ..The present study was undertaken to detect the possible association of polymorphisms in the ABCA1 gene [rs2230806 (R219K) and rs2230808 (R1587K)] and lipid profile in Greek young nurses...
  33. pmc Cholesteryl ester transfer protein gene polymorphisms and longevity syndrome
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Open Cardiovasc Med J 4:14-9. 2010
    ..Since HDL particles are influenced by cholesteryl ester transfer protein (CETP) activity, it is worth studying the CETP polymorphism. The aim of the study was to detect whether 2 genetic variants of the CETP are associated with the LS...
  34. doi request reprint Gene polymorphisms and thyroid function in patients with heart failure
    Ioannis Vasiliadis
    Cardiology Department, Onassis Cardiac Surgery Center Athens, 356 Sygrou Ave, 176 74, Athens, Greece
    Endocrine 45:46-54. 2014
    ..Thyroid hormones correlated with CV capacity. Associations between the NFkB and ACE gene polymorphisms and thyroid hormones levels were also observed. Further larger studies are required to clarify genes contribution in HF. ..
  35. doi request reprint Evaluation of myocarditis in a pediatric population using cardiovascular magnetic resonance and endomyocardial biopsy
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece
    Int J Cardiol 160:192-5. 2012
    ..To evaluate myocarditis in a pediatric population using cardiovascular magnetic resonance (CMR) and endomyocardial biopsy...
  36. ncbi request reprint Apolipoprotein E polymorphism and atherosclerosis
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Angiology 54:59-71. 2003
    ..Whatever the future brings, the evaluation of apo E genotypes will need to be rapid, cheap, and technically undemanding before this investigation becomes widely available and clinically relevant...
  37. doi request reprint Myocarditis as a precipitating factor for heart failure: evaluation and 1-year follow-up using cardiovascular magnetic resonance and endomyocardial biopsy
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, 50 Esperou Street, 175 61 P Faliro, Athens, Greece
    Eur J Heart Fail 13:830-7. 2011
    ..The aim of this study was to evaluate myocarditis as a precipitating factor for heart failure using cardiovascular magnetic resonance (CMR) and endomyocardial biopsy...
  38. doi request reprint Cardiac tissue characterization and the diagnostic value of cardiovascular magnetic resonance in systemic connective tissue diseases
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece
    Arthritis Care Res (Hoboken) 66:104-12. 2014
    ..We hypothesized that cardiovascular magnetic resonance (CMR) demonstrates cardiac lesions in symptomatic CTD patients with normal echocardiography...
  39. ncbi request reprint Myocardial inflammation in autoimmune diseases: investigation by cardiovascular magnetic resonance and endomyocardial biopsy
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Esperou Street, 175 61 P Faliro, Greece
    Inflamm Allergy Drug Targets 8:390-7. 2009
    ..Myocardial inflammation often coexists with different types of autoimmune diseases. Our aim was to investigate the presence of myocarditis in these patients by Cardiovascular Magnetic Resonance (CMR) and endomyocardial biopsy...
  40. ncbi request reprint Regression of Achilles tendon xanthomas evaluated by CT scan after hypolipidemic treatment with simvastatin. A case report
    Genovefa Kolovou
    1st Cardiology Department of the Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 55:335-9. 2004
    ..As XAT are atherosclerotic plaque-like depositions of lipids it is likely that their progression or regression follows the behavior of vascular atherosclerotic lesions...
  41. ncbi request reprint The Greek cardiac magnetic resonance experience: a comparison with the EuroCMR Registry
    Sophie Mavrogeni
    Onassis Cardiac Surgery Centre, Athens, Greece
    Hellenic J Cardiol 54:355-61. 2013
    ..We carried out an evaluation of Greek cardiovascular magnetic resonance (CMR) data in order to analyse the indications, safety, quality, and impact on management, in comparison with the EuroCMR registry...
  42. ncbi request reprint Streptococcal tonsillitis and acute streptococcal myocarditis: an unusual combination assessed by cardiac magnetic resonance imaging and endomyocardial biopsy
    Sophie Mavrogeni
    Cardiac Clinic, Onassis Cardiac Surgery Center, Sismanoglion Hospital, Athens, Greece
    Ann Otol Rhinol Laryngol 121:604-8. 2012
    ..Acute streptococcal tonsillitis is occasionally combined with myocarditis. Our aim was to examine patients with tonsillitis in whom myocarditis was suspected by using cardiac magnetic resonance imaging (MRI) and endomyocardial biopsy...
  43. pmc Changes in Lipids and Lipoproteins after Selective LDL Apheresis (7-Year Experience)
    Genovefa Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece
    Cholesterol 2012:976578. 2012
    ..The average annual event rate was 5.51%. Conclusion. LDL apheresis is a very important therapeutic tool in managing patients at high risk for premature CAD or with aggressive CAD, despite adequate medical treatment...
  44. ncbi request reprint Myopericarditis, as the first sign of rheumatoid arthritis relapse, evaluated by cardiac magnetic resonance
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece
    Inflamm Allergy Drug Targets 12:206-11. 2013
    ..Rheumatoid arthritis (RA) affects many organs, including the heart. Cardiac magnetic resonance (CMR) can assess heart pathophysiology in RA...
  45. doi request reprint Effect of iron overload on exercise capacity in thalassemic patients with heart failure
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece
    Int J Cardiovasc Imaging 25:777-83. 2009
    ..001). HF thalassemic patients have reduced exercise indexes compared to non HF. Myocardial iron overload, expressed as T2*, has a direct influence on exercise capacity, independent of LV ejection fraction and functional class...
  46. doi request reprint Effect of deflazacort on cardiac and sternocleidomastoid muscles in Duchenne muscular dystrophy: a magnetic resonance imaging study
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Pendeli Children s Hospital, Athens, Greece
    Eur J Paediatr Neurol 13:34-40. 2009
    ....
  47. pmc Platelet activating factor levels and metabolism in Tangier disease: a case study
    Vana Kolovou
    Cardiology Department and Molecular Immunology Laboratory, Onassis Cardiac Surgery Center, Athens, Greece
    Lipids Health Dis 11:89. 2012
    ....
  48. pmc One more look at guidelines for primary and secondary prevention of cardiovascular disease in women
    Genovefa Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Arch Med Sci 7:747-55. 2011
    ..In this review, the guidelines or recommendations which have been reported in the last 2 decades by various scientific societies for prevention of cardiovascular disease in women will be analysed...
  49. doi request reprint Myocardial involvement in a patient with chlamydia trachomatis infection
    Sophie Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece
    J Card Fail 14:351-3. 2008
  50. ncbi request reprint Cardiac involvement in ANCA (+) and ANCA (-) Churg-Strauss syndrome evaluated by cardiovascular magnetic resonance
    Sophie Mavrogeni
    50 Esperou Street, 175 61 P Faliro, Athens, Greece
    Inflamm Allergy Drug Targets 12:322-7. 2013
    ....
  51. ncbi request reprint Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis
    Constantinos Mihas
    Internal Medicine Department, General Hospital of Kimi, Kimi, Greece
    Curr Vasc Pharmacol 9:271-80. 2011
    ..The aim of this study was to evaluate how non-fasting TG levels vary after an oral FTT in healthy subjects...