G D Kolovou

Summary

Affiliation: Onassis Cardiac Surgery Center
Country: Greece

Publications

  1. ncbi Pathophysiology of dyslipidaemia in the metabolic syndrome
    G D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Postgrad Med J 81:358-66. 2005
  2. ncbi Postprandial lipemia in men with metabolic syndrome, hypertensives and healthy subjects
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Lipids Health Dis 4:21. 2005
  3. ncbi Apolipoprotein E genotype in matched men and women with coronary heart disease
    Genovefa D Kolovou
    Onassis Cardiac Surgery Center, 356 Sygrou Ave, 176 74 Athens, Greece
    Ann Clin Lab Sci 35:391-6. 2005
  4. ncbi Association of apolipoprotein E genotype with early onset of coronary heart disease in Greek men
    Genovefa D Kolovou
    Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 56:663-70. 2005
  5. ncbi Management of a patient with a null low-density lipoprotein receptor mutation: a case report
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 57:729-32. 2006
  6. ncbi Postprandial lipemia in postmenopausal women with high fasting high-density lipoprotein cholesterol
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Tzanio State Hospital, Piraeus, Greece
    Am J Med Sci 331:10-6. 2006
  7. ncbi Postprandial lipaemia in menopausal women with metabolic syndrome
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Ave, 17674 Athens, Greece
    Maturitas 55:19-26. 2006
  8. ncbi Cholesteryl ester transfer protein gene polymorphisms and severity of coronary stenosis
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Clin Invest Med 29:14-9. 2006
  9. ncbi Tangier disease four decades of research: a reflection of the importance of HDL
    G D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Med Chem 13:771-82. 2006
  10. ncbi Lipid profile of women qualifying for hypolipidaemic treatment
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Acta Cardiol 61:440-5. 2006

Detail Information

Publications41

  1. ncbi Pathophysiology of dyslipidaemia in the metabolic syndrome
    G D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Postgrad Med J 81:358-66. 2005
    ..The widely prevalent nature of the metabolic syndrome emphasises the importance of its diagnosis and treatment. This review analyses the clinical and dynamic features of this syndrome in the aspect of dyslipidaemia and its management...
  2. ncbi Postprandial lipemia in men with metabolic syndrome, hypertensives and healthy subjects
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Lipids Health Dis 4:21. 2005
    ..This study aimed to evaluate the postprandial lipemia after oral fat tolerance test (OFTT) in subjects with MetS and compare them to hypertensive (HTN) and healthy subjects...
  3. ncbi Apolipoprotein E genotype in matched men and women with coronary heart disease
    Genovefa D Kolovou
    Onassis Cardiac Surgery Center, 356 Sygrou Ave, 176 74 Athens, Greece
    Ann Clin Lab Sci 35:391-6. 2005
    ..The E3/3 men patients were more frequently part of a family with a history of CHD, compared to women (p=0.035)...
  4. ncbi Association of apolipoprotein E genotype with early onset of coronary heart disease in Greek men
    Genovefa D Kolovou
    Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 56:663-70. 2005
    ..Because the results of similar studies are not consistent, it may be that the relationship between apo E genotype and CHD is related to ethnicity rather than a universal phenomenon...
  5. ncbi Management of a patient with a null low-density lipoprotein receptor mutation: a case report
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 57:729-32. 2006
    ..Furthermore, the coadministration of statins, cholestyramine, and ezetimibe during low-density lipoprotein-apheresis tends to counterbalance the postapheresis relapse in low-density lipoprotein cholesterol levels...
  6. ncbi Postprandial lipemia in postmenopausal women with high fasting high-density lipoprotein cholesterol
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Tzanio State Hospital, Piraeus, Greece
    Am J Med Sci 331:10-6. 2006
    ..The purpose of this study was to test the effect of high fasting high-density lipoprotein cholesterol (HDL-C) levels on PPL in postmenopausal females...
  7. ncbi Postprandial lipaemia in menopausal women with metabolic syndrome
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Ave, 17674 Athens, Greece
    Maturitas 55:19-26. 2006
    ..Postprandial hypertriglyceridaemia is also associated with CHD. The aim of this study was to evaluate the postprandial lipaemia after an oral fat tolerance test (OFTT) in women with MetS...
  8. ncbi Cholesteryl ester transfer protein gene polymorphisms and severity of coronary stenosis
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Clin Invest Med 29:14-9. 2006
    ....
  9. ncbi Tangier disease four decades of research: a reflection of the importance of HDL
    G D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Med Chem 13:771-82. 2006
    ..This review focuses on the genetic and lipid abnormalities of TD, the consequence of these on clinical outcome and the possible treatment options. These abnormalities reflect the importance of HDL in the pathogenesis of vascular disease...
  10. ncbi Lipid profile of women qualifying for hypolipidaemic treatment
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Acta Cardiol 61:440-5. 2006
    ..Death rates from coronary heart disease continue to rise in women despite a marked decrease in men for the past two decades. Our study aimed to evaluate essential risk factors in high-risk adult women...
  11. ncbi Clinical relevance of postprandial lipaemia
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Med Chem 12:1931-45. 2005
    ..Treatment may involve lifestyle measures as well as the use of lipid lowering (e.g. fibrates or statins), weight reducing and hypoglycaemic drugs...
  12. ncbi Influence of triglycerides on other plasma lipids in middle-aged men intended for hypolipidaemic treatment
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Hellenic J Cardiol 47:78-83. 2006
    ..The present investigation aimed to evaluate the influence of serum triglycerides (TG) on other plasma lipids in male patients less than 65 years of age intended for hypolipidaemic treatment...
  13. ncbi Cholesterol ester transfer protein (CETP), postprandial lipemia and hypolipidemic drugs
    G D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Ave 176 74 Athens, Greece
    Curr Med Chem 16:4345-60. 2009
    ..We also discuss gender influence on the action of hypolipidemic drugs and their effect on CETP mass and activity, as well as on the lipid profile...
  14. ncbi Fasting serum triglyceride and high-density lipoprotein cholesterol levels in patients intended to be treated for dyslipidemia
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Vasc Health Risk Manag 1:155-61. 2005
    ..The aim of the present investigation was to evaluate the influence of serum triglycerides (TG) on other plasma lipids in patients to be treated for dyslipidemia...
  15. ncbi Alcohol use, vascular disease, and lipid-lowering drugs
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece, and Department of Clinical Biochemistry, Vascular Disease Prevention Clinics, Royal Free Hospital, Royal Free and University College Medical School, London, UK
    J Pharmacol Exp Ther 318:1-7. 2006
    ..In the present review, the beneficial effects of Alc consumption on CHD risk, its side effects, and its safety and suitability when coadministered with hypolipidemic drugs are discussed...
  16. ncbi The effect of alcohol and gemfibrozil co-administration in Wistar rats
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    In Vivo 18:49-53. 2004
    ..Since both Alc and Gem can disturb liver function, we assessed the effects of administering Alc together with Gem in Wistar rats...
  17. ncbi The influence of natural menopause on postprandial lipemia in heterozygotes for familial hypercholesterolemia
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    J Womens Health (Larchmt) 13:1119-26. 2004
    ..Raised plasma triglyceride (TG) levels also contribute to the risk of vascular events. The aim of this study was to evaluate the postprandial TG levels (after a standardized fatty meal) in premenopausal and postmenopausal women with hFH...
  18. ncbi The effect of nicotinic acid and alcohol co-administration in Wistar rats
    G D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Methods Find Exp Clin Pharmacol 27:17-23. 2005
    ..Liver histopathology was within the normal range. A moderate amount of Alc daily together with NA is safe in rats. The NA and Alc co-administration reduces the TG and AST levels in rats, compared with the administration of Alc alone...
  19. ncbi Heterozygote men with familial hypercholesterolaemia may have an abnormal triglyceride response post-prandially. Evidence for another predictor of vascular risk in familial hypercholesterolaemia
    G D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece
    Int J Clin Pract 59:311-7. 2005
    ..The reduced activity of low-density lipoprotein receptors in hFH together with other defects in TG handling may explain the abnormal rise of TG levels post-prandially...
  20. ncbi The epsilon 2 and 4 alleles of apolipoprotein E and ischemic vascular events in the Greek population--implications for the interpretation of similar studies
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Angiology 54:51-8. 2003
    ..These results suggest that the epsilon4 and epsilon2 alleles have a variable significance in terms of predicting the risk of vascular events in different populations. Therefore, it is important to carry out "local" studies...
  21. ncbi Apolipoprotein E gene polymorphism and obesity status in middle-aged men with coronary heart disease
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    In Vivo 23:33-9. 2009
    ..Apolipoprotein (apo) E polymorphism has been associated with coronary heart disease (CHD) and obesity. We aimed to determine whether apoE polymorphism is related to CHD in patients with different body mass index (BMI)...
  22. ncbi Apolipoprotein E polymorphism, age and coronary heart disease
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Ave, 176 74 Athens, Greece
    Ageing Res Rev 6:94-108. 2007
    ..If apo E polymorphism is an important genetic factor in the pathogenesis of atherosclerosis, it could affect the age of CHD onset. This review analyses the influence of apo E polymorphism on blood lipids and CHD in respect to age...
  23. ncbi Metabolic syndrome and gender differences in postprandial lipaemia
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Eur J Cardiovasc Prev Rehabil 13:661-4. 2006
    ..Postprandial hyperlipidaemia may be a predictor of vascular risk...
  24. ncbi The effect of co-administration of simvastatin and alcohol in rats
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Ave, 176 74 Athens, Greece
    In Vivo 17:523-7. 2003
    ..We studied the effects of administering Alc together with a 3-hydroxy-3 methylglutaryl coenzyme A reductase inhibitor [simvastatin (S)]...
  25. ncbi Gender influence on postprandial lipemia in heterozygotes for familial hypercholesterolemia
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Ann Clin Lab Sci 37:335-42. 2007
    ..In summary, hFH men have higher BMI, fasting TG level, and postprandial TG level, compared to age-matched premenopausal hFH women, which may partially explain the earlier onset of coronary heart disease in hFH men...
  26. ncbi Comparison of simvastatin and nicotinic acid administration in alcohol-treated Wistar rats
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece
    Hellenic J Cardiol 49:79-85. 2008
    ..The aim of this study was to evaluate which drug is more effective and safe in decreasing Alc-induced hypertriglyceridaemia in Wistar rats...
  27. ncbi Postprandial lipemia in hypertension
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    J Am Coll Nutr 22:80-7. 2003
    ..001, p < 0.001 and p < 0.001, respectively. CONCLUSION: This study suggests that patients with hypertension have an exaggerated response and delayed clearance of plasma TG concentration after fat loading...
  28. ncbi The effect of statins on postprandial lipemia
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Drug Targets 8:551-60. 2007
    ..Since abnormal postprandial lipemia is associated with pathological conditions, its treatment is relevant. This review considers the effect of statins on postprandial lipemia...
  29. ncbi Sex-associated effect of CETP and LPL polymorphisms on postprandial lipids in familial hypercholesterolaemia
    Katherine K Anagnostopoulou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Lipids Health Dis 8:24. 2009
    ....
  30. ncbi Increase in aortic pulse wave velocity is associated with abnormal postprandial triglyceride response
    Deliana C Daskalova
    Cardiology Department, Onassis Cardiac Surgery Center, Harokopio University, University Medical School, Athens, Greece
    Clin Cardiol 28:577-83. 2005
    ..These relationships, reported here for the first time, could be of practical use for better evaluation of patient prognosis...
  31. ncbi Long-term clinical outcome of coronary artery stenting in elderly patients
    Vassilis A Voudris
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Coron Artery Dis 13:323-9. 2002
    ..In the present study we retrospectively assessed the long-term clinical outcome of coronary artery stenting in an elderly population and compared them with the cohort of younger patients...
  32. ncbi ROS1 Asp2213Asn polymorphism is not associated with coronary artery disease in a Greek case-control study
    Eirini V Theodoraki
    Department of Dietetics and Nutritional Science, Harokopio University of Athens, Athens, Greece
    Clin Chem Lab Med 47:1471-3. 2009
    ..We investigated the role of ROS1 rs529038 polymorphism in coronary artery disease (CAD) in Greeks using a case-control study...
  33. ncbi Therapeutic effects of fibrates in postprandial lipemia
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Cardiovasc Drugs 8:243-55. 2008
    ..Fibrates are well tolerated by patients and adverse effects have been reported rarely after their administration...
  34. ncbi Influence of aging and menopause on lipids and lipoproteins in women
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 59:54S-7S. 2008
    ..In this review, the current understanding of an influence of age and menopause on lipids and lipoproteins concentration in women will be analyzed...
  35. ncbi Low serum levels of high-density lipoprotein cholesterol and hypolipidaemic treatment
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Curr Med Res Opin 18:265-8. 2002
    ..Raising HDL cholesterol should be an important therapeutic goal in patients with coronary artery disease. Fibrates can reduce the risk of cardiac events and death from coronary artery disease...
  36. ncbi Gender differences in the lipid profile of dyslipidemic subjects
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Eur J Intern Med 20:145-51. 2009
    ..We evaluated the gender-associated differences in lipid profile of subjects intended to receive lipid-lowering therapy with emphasis on the associations between triglycerides (TG) and other plasma lipid variables...
  37. ncbi Simvastatin: two decades in a circle
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Cardiovasc Ther 26:166-78. 2008
    ..In this review, we will present all these effects, as well as the beneficial effects on atherogenesis and the reduction in cardiovascular morbidity and mortality related to simvastatin...
  38. ncbi The prevalence of metabolic syndrome in various populations
    Genovefa D Kolovou
    Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Med Sci 333:362-71. 2007
    ..This review also considers the impact of metabolic syndrome on cardiovascular disease...
  39. ncbi Effect of baseline levels on response of high-density lipoprotein cholesterol to hypolipidemic treatment
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Cardiol 92:1339-42. 2003
    ..We hypothesized that the behavior of high-density lipoprotein cholesterol after treatment would depend on its baseline levels and the therapy used...
  40. ncbi Mortality after first myocardial infarction in Greek patients: a 4-year follow-up study
    Genovefa D Kolovou
    First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
    Angiology 60:582-7. 2009
    ..Death associated with coronary heart disease (CHD) depends in part on the time since the myocardial infarction (MI) and modification of risk factors...
  41. ncbi Primary and secondary hypertriglyceridaemia
    Genovefa D Kolovou
    1st Cardiology Department, Onassis Cardiac Surgery Center Athens, Greece
    Curr Drug Targets 10:336-43. 2009
    ..Also, hypertriglyceridaemia (TG >150 mg/dl; 1.7 mmol/l) is one of the diagnostic criteria of metabolic syndrome. Finally, several drugs may increase TG levels (e.g. chlorthalidone or beta-blockers)...