Drakoulis Yannoukakos

Summary

Affiliation: NCSR Demokritos
Country: Greece

Publications

  1. ncbi Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families
    Georgia Thodi
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:544. 2010
  2. ncbi Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center of Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:389. 2010
  3. ncbi Hereditary cancer syndromes
    Florentia Fostira
    Molecular Diagnostics Laboratory, I RRP, National Centre for Scientific Research Demokritos, Athens, Greece
    J BUON 12:S13-22. 2007
  4. ncbi G1738R is a BRCA1 founder mutation in Greek breast/ovarian cancer patients: evaluation of its pathogenicity and inferences on its genealogical history
    Theodore Anagnostopoulos
    Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research Demokritos, Aghia Paraskevi, Athens, Greece
    Breast Cancer Res Treat 110:377-85. 2008
  5. ncbi Novel genomic rearrangements in the BRCA1 gene detected in Greek breast/ovarian cancer patients
    Sophia Armaou
    Molecular Diagnostics Laboratory, I R RP, National Centre for Scientific Research Demokritos, Athens, Greece
    Eur J Cancer 43:443-53. 2007
  6. ncbi Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients
    Irene Konstantopoulou
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Breast Cancer Res Treat 107:431-41. 2008
  7. ncbi A distinct mutation on the alternative splice site of APC exon 9 results in attenuated familial adenomatous polyposis phenotype
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Fam Cancer 9:395-400. 2010
  8. ncbi An in-frame exon-skipping MUTYH mutation is associated with early-onset colorectal cancer
    Florentia Fostira
    Molecular Diagnostics Laboratory, National Centre of Scientific Research Demokritos, I RRP, Athens, Greece
    Dis Colon Rectum 53:1197-201. 2010
  9. ncbi Characterization of a novel large deletion and single point mutations in the BRCA1 gene in a Greek cohort of families with suspected hereditary breast cancer
    Ioulia Belogianni
    Molecular Biology Research Center HYGEIA Antonis Papayiannia, DTCA HYGEIA, 15123 Maroussi, Athens, Greece
    BMC Cancer 4:61. 2004
  10. ncbi Culture of primary epithelial adenoma cells from familial adenomatous polyposis patients
    Florentia Fostira
    Molecular Diagnostics Lab, I RRP, National Center for Scientific Research Demokritos, Athens, Greece
    Anticancer Res 28:843-6. 2008

Collaborators

  • Ioulia Belogianni
  • Konstantinos Misiakos
  • George Fountzilas
  • Markos Mihalatos
  • Ioannis Boukovinas
  • Dimitrios Linos
  • Charisios Karanikiotis
  • Evangelia Razi
  • Panagiota S Petrou
  • Paris A Kosmidis
  • Florentia Fostira
  • Irene Konstantopoulou
  • Georgia Thodi
  • Theodore Anagnostopoulos
  • Raphael Sandaltzopoulos
  • George Nasioulas
  • Sophia Armaou
  • Smaragda Kamakari
  • George Koutsodontis
  • Evangelia Razis
  • Thalia Bei
  • Sotirios Bethanis
  • Angela Ladopoulou
  • Athanasios Armakolas
  • Constantinos Papademitriou
  • Maria Mylonaki
  • Anastasios Grivas
  • Anna Efremidis
  • Mirjana Brankovic Magic
  • Christos Panopoulos
  • Eutyxia Oikonomou
  • Maroulio Pertesi
  • Nikos Pandis
  • David Goldgar
  • Angela Apessos
  • Christos Markopoulos
  • Ladislav Andera
  • Helen Gogas
  • Panos Kouklis
  • George Nikolopoulos
  • Athanassios Athanasiou
  • Dimosthenis Skarlos
  • Mary Anne Young
  • Theodore Rampias
  • Iordanis Arzimanoglou
  • Alexander Pintzas
  • Antonios Keramopoulos
  • Sofia Armaou
  • Grigoris Manifikos
  • Antonis Stylianakis
  • Alex Dobrovic
  • Vassiliki Gaki
  • George Nounesis
  • Sotiris Baratsis
  • Theodosia Palouka
  • Savas Papadopoulos
  • Christos Avgoustis
  • Stylianos Tsagarakis
  • Nikolaos Xenidis
  • Christopher Markopoulos
  • Ilias P Gomatos
  • B Pararas
  • Manoussos M Konstadoulakis
  • Ioannis Gogas
  • Emmanouil Leandros
  • Agapi Kataki
  • George Androulakis
  • George P Stathopoulos

Detail Information

Publications14

  1. ncbi Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families
    Georgia Thodi
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:544. 2010
    ....
  2. ncbi Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center of Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:389. 2010
    ..Additionally, all available published mutations were considered in order to define the APC mutation spectrum in Greece...
  3. ncbi Hereditary cancer syndromes
    Florentia Fostira
    Molecular Diagnostics Laboratory, I RRP, National Centre for Scientific Research Demokritos, Athens, Greece
    J BUON 12:S13-22. 2007
    ....
  4. ncbi G1738R is a BRCA1 founder mutation in Greek breast/ovarian cancer patients: evaluation of its pathogenicity and inferences on its genealogical history
    Theodore Anagnostopoulos
    Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research Demokritos, Aghia Paraskevi, Athens, Greece
    Breast Cancer Res Treat 110:377-85. 2008
    ..Considering the large degree of genetic heterogeneity in the Greek population, the identification of a frequent founder mutation greatly facilitates genetic screening...
  5. ncbi Novel genomic rearrangements in the BRCA1 gene detected in Greek breast/ovarian cancer patients
    Sophia Armaou
    Molecular Diagnostics Laboratory, I R RP, National Centre for Scientific Research Demokritos, Athens, Greece
    Eur J Cancer 43:443-53. 2007
    ....
  6. ncbi Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients
    Irene Konstantopoulou
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Breast Cancer Res Treat 107:431-41. 2008
    ..The suggested protocol can impact on the clinical management of breast-ovarian cancer families on a national healthcare system level...
  7. ncbi A distinct mutation on the alternative splice site of APC exon 9 results in attenuated familial adenomatous polyposis phenotype
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Fam Cancer 9:395-400. 2010
    ....
  8. ncbi An in-frame exon-skipping MUTYH mutation is associated with early-onset colorectal cancer
    Florentia Fostira
    Molecular Diagnostics Laboratory, National Centre of Scientific Research Demokritos, I RRP, Athens, Greece
    Dis Colon Rectum 53:1197-201. 2010
    ..The aim of this study was to investigate the pathogenicity of the 13-base-pair deletion, c.504 + 19_504 + 31del13, located on intron 6 of the MUTYH gene, which was identified in 2 unrelated Greek patients with MUTYH-associated polyposis...
  9. ncbi Characterization of a novel large deletion and single point mutations in the BRCA1 gene in a Greek cohort of families with suspected hereditary breast cancer
    Ioulia Belogianni
    Molecular Biology Research Center HYGEIA Antonis Papayiannia, DTCA HYGEIA, 15123 Maroussi, Athens, Greece
    BMC Cancer 4:61. 2004
    ..A multitude of mutations have been described and are found to be scattered throughout these two large genes. We describe analysis of BRCA1 in 25 individuals from 18 families from a Greek cohort...
  10. ncbi Culture of primary epithelial adenoma cells from familial adenomatous polyposis patients
    Florentia Fostira
    Molecular Diagnostics Lab, I RRP, National Center for Scientific Research Demokritos, Athens, Greece
    Anticancer Res 28:843-6. 2008
    ..The goal of this study was the establishment of conditions for the culture of epithelial cells composing an adenomatic structure...
  11. ncbi Evaluation of dHPLC in mutation screening of the APC gene in a Greek FAP cohort
    Markos Mihalatos
    Molecular Biology Research Center HYGEIA, Antonis Papayiannis, Kifissias Ave. and Erythrou Stavrou 4 Str, 15123 Maroussi, Athens, Greece
    Anticancer Res 23:2691-5. 2003
    ..All 14 mutations identified by sequencing were also detected using dHPLC. Sequence analysis of a large family confirmed the dHPLC results. CONCLUSION: Using dHPLC we detected all mutations previously identified by sequencing...
  12. ncbi A newly detected mutation of the RET protooncogene in exon 8 as a cause of multiple endocrine neoplasia type 2A
    Sotirios Bethanis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    Hormones (Athens) 6:152-6. 2007
    ..Furthermore, patients with FMTC and exon 8 mutations should also be screened for pheochromocytoma...
  13. ncbi Fully integrated monolithic optoelectronic transducer for real-time protein and DNA detection: the NEMOSLAB approach
    Konstantinos Misiakos
    Institute of Microelectronics, N C S R Demokritos, GR 15310 Aghia Paraskevi, Athens, Attiki, Greece
    Biosens Bioelectron 26:1528-35. 2010
    ..The proposed miniaturized sensing device with proper packaging and accompanied by a portable instrument can find wide application as a platform for reliable and cost effective point-of-care diagnosis...
  14. ncbi BRCA2 gene mutations in Greek patients with familial breast cancer
    Athanasios Armakolas
    Laboratory of Surgical Research, A Propaedeutic Surgical Clinic, Athens Medical School, Hippokrateion Hospital, Athens, Greece
    Hum Mutat 19:81-2. 2002
    ..Our findings suggest that there is a cluster of novel mutations in exons 10 and 11 in Greek patients with familial breast cancer. These mutations appear to have a milder clinical phenotype when compared to the rest of the study group...