Drakoulis Yannoukakos

Summary

Affiliation: NCSR Demokritos
Country: Greece

Publications

  1. pmc Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families
    Georgia Thodi
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:544. 2010
  2. pmc Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center of Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:389. 2010
  3. ncbi request reprint Hereditary cancer syndromes
    Florentia Fostira
    Molecular Diagnostics Laboratory, I RRP, National Centre for Scientific Research Demokritos, Athens, Greece
    J BUON 12:S13-22. 2007
  4. ncbi request reprint G1738R is a BRCA1 founder mutation in Greek breast/ovarian cancer patients: evaluation of its pathogenicity and inferences on its genealogical history
    Theodore Anagnostopoulos
    Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research Demokritos, Aghia Paraskevi, Athens, Greece
    Breast Cancer Res Treat 110:377-85. 2008
  5. ncbi request reprint Novel genomic rearrangements in the BRCA1 gene detected in Greek breast/ovarian cancer patients
    Sophia Armaou
    Molecular Diagnostics Laboratory, I R RP, National Centre for Scientific Research Demokritos, Athens, Greece
    Eur J Cancer 43:443-53. 2007
  6. ncbi request reprint Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients
    Irene Konstantopoulou
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Breast Cancer Res Treat 107:431-41. 2008
  7. doi request reprint A distinct mutation on the alternative splice site of APC exon 9 results in attenuated familial adenomatous polyposis phenotype
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Fam Cancer 9:395-400. 2010
  8. doi request reprint An in-frame exon-skipping MUTYH mutation is associated with early-onset colorectal cancer
    Florentia Fostira
    Molecular Diagnostics Laboratory, National Centre of Scientific Research Demokritos, I RRP, Athens, Greece
    Dis Colon Rectum 53:1197-201. 2010
  9. pmc Characterization of a novel large deletion and single point mutations in the BRCA1 gene in a Greek cohort of families with suspected hereditary breast cancer
    Ioulia Belogianni
    Molecular Biology Research Center HYGEIA Antonis Papayiannia, DTCA HYGEIA, 15123 Maroussi, Athens, Greece
    BMC Cancer 4:61. 2004
  10. ncbi request reprint Culture of primary epithelial adenoma cells from familial adenomatous polyposis patients
    Florentia Fostira
    Molecular Diagnostics Lab, I RRP, National Center for Scientific Research Demokritos, Athens, Greece
    Anticancer Res 28:843-6. 2008

Collaborators

  • Ioulia Belogianni
  • Konstantinos Misiakos
  • George Fountzilas
  • Markos Mihalatos
  • Ioannis Boukovinas
  • Dimitrios Linos
  • Charisios Karanikiotis
  • Evangelia Razi
  • Panagiota S Petrou
  • Paris A Kosmidis
  • Florentia Fostira
  • Irene Konstantopoulou
  • Georgia Thodi
  • Theodore Anagnostopoulos
  • Raphael Sandaltzopoulos
  • George Nasioulas
  • Sophia Armaou
  • Smaragda Kamakari
  • Thalia Bei
  • George Koutsodontis
  • Evangelia Razis
  • Sotirios Bethanis
  • Angela Ladopoulou
  • Athanasios Armakolas
  • Anastasios Grivas
  • Mirjana Brankovic Magic
  • Maria Mylonaki
  • Constantinos Papademitriou
  • Anna Efremidis
  • Christos Panopoulos
  • Angela Apessos
  • Sofia Armaou
  • Dimosthenis Skarlos
  • Christos Markopoulos
  • Athanassios Athanasiou
  • George Nounesis
  • Helen Gogas
  • Eutyxia Oikonomou
  • Panos Kouklis
  • David Goldgar
  • Vassiliki Gaki
  • Ladislav Andera
  • Mary Anne Young
  • George Nikolopoulos
  • Antonios Keramopoulos
  • Maroulio Pertesi
  • Iordanis Arzimanoglou
  • Grigoris Manifikos
  • Antonis Stylianakis
  • Alex Dobrovic
  • Nikos Pandis
  • Theodore Rampias
  • Alexander Pintzas
  • Sotiris Baratsis
  • Theodosia Palouka
  • Stylianos Tsagarakis
  • Nikolaos Xenidis
  • Savas Papadopoulos
  • Christos Avgoustis
  • Emmanouil Leandros
  • Christopher Markopoulos
  • Manoussos M Konstadoulakis
  • Agapi Kataki
  • George Androulakis
  • George P Stathopoulos
  • Ioannis Gogas
  • Ilias P Gomatos
  • B Pararas

Detail Information

Publications14

  1. pmc Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families
    Georgia Thodi
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:544. 2010
    ....
  2. pmc Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center of Scientific Research Demokritos, Athens, Greece
    BMC Cancer 10:389. 2010
    ..Additionally, all available published mutations were considered in order to define the APC mutation spectrum in Greece...
  3. ncbi request reprint Hereditary cancer syndromes
    Florentia Fostira
    Molecular Diagnostics Laboratory, I RRP, National Centre for Scientific Research Demokritos, Athens, Greece
    J BUON 12:S13-22. 2007
    ....
  4. ncbi request reprint G1738R is a BRCA1 founder mutation in Greek breast/ovarian cancer patients: evaluation of its pathogenicity and inferences on its genealogical history
    Theodore Anagnostopoulos
    Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research Demokritos, Aghia Paraskevi, Athens, Greece
    Breast Cancer Res Treat 110:377-85. 2008
    ..Considering the large degree of genetic heterogeneity in the Greek population, the identification of a frequent founder mutation greatly facilitates genetic screening...
  5. ncbi request reprint Novel genomic rearrangements in the BRCA1 gene detected in Greek breast/ovarian cancer patients
    Sophia Armaou
    Molecular Diagnostics Laboratory, I R RP, National Centre for Scientific Research Demokritos, Athens, Greece
    Eur J Cancer 43:443-53. 2007
    ....
  6. ncbi request reprint Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients
    Irene Konstantopoulou
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Breast Cancer Res Treat 107:431-41. 2008
    ..The suggested protocol can impact on the clinical management of breast-ovarian cancer families on a national healthcare system level...
  7. doi request reprint A distinct mutation on the alternative splice site of APC exon 9 results in attenuated familial adenomatous polyposis phenotype
    Florentia Fostira
    Molecular Diagnostics Laboratory, I R RP, National Center for Scientific Research Demokritos, Athens, Greece
    Fam Cancer 9:395-400. 2010
    ....
  8. doi request reprint An in-frame exon-skipping MUTYH mutation is associated with early-onset colorectal cancer
    Florentia Fostira
    Molecular Diagnostics Laboratory, National Centre of Scientific Research Demokritos, I RRP, Athens, Greece
    Dis Colon Rectum 53:1197-201. 2010
    ..The aim of this study was to investigate the pathogenicity of the 13-base-pair deletion, c.504 + 19_504 + 31del13, located on intron 6 of the MUTYH gene, which was identified in 2 unrelated Greek patients with MUTYH-associated polyposis...
  9. pmc Characterization of a novel large deletion and single point mutations in the BRCA1 gene in a Greek cohort of families with suspected hereditary breast cancer
    Ioulia Belogianni
    Molecular Biology Research Center HYGEIA Antonis Papayiannia, DTCA HYGEIA, 15123 Maroussi, Athens, Greece
    BMC Cancer 4:61. 2004
    ..A multitude of mutations have been described and are found to be scattered throughout these two large genes. We describe analysis of BRCA1 in 25 individuals from 18 families from a Greek cohort...
  10. ncbi request reprint Culture of primary epithelial adenoma cells from familial adenomatous polyposis patients
    Florentia Fostira
    Molecular Diagnostics Lab, I RRP, National Center for Scientific Research Demokritos, Athens, Greece
    Anticancer Res 28:843-6. 2008
    ..The goal of this study was the establishment of conditions for the culture of epithelial cells composing an adenomatic structure...
  11. ncbi request reprint Evaluation of dHPLC in mutation screening of the APC gene in a Greek FAP cohort
    Markos Mihalatos
    Molecular Biology Research Center HYGEIA, Antonis Papayiannis, Kifissias Ave and Erythrou Stavrou 4 Str, 15123 Maroussi, Athens, Greece
    Anticancer Res 23:2691-5. 2003
    ..A multitude of mutations, dispersed throughout the gene, have been described. We wanted to evaluate the usefulness of denaturing high performance liquid chromatography (dHPLC) for mutation screening...
  12. ncbi request reprint A newly detected mutation of the RET protooncogene in exon 8 as a cause of multiple endocrine neoplasia type 2A
    Sotirios Bethanis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    Hormones (Athens) 6:152-6. 2007
    ..Furthermore, patients with FMTC and exon 8 mutations should also be screened for pheochromocytoma...
  13. doi request reprint Fully integrated monolithic optoelectronic transducer for real-time protein and DNA detection: the NEMOSLAB approach
    Konstantinos Misiakos
    Institute of Microelectronics, N C S R Demokritos, GR 15310 Aghia Paraskevi, Athens, Attiki, Greece
    Biosens Bioelectron 26:1528-35. 2010
    ..The proposed miniaturized sensing device with proper packaging and accompanied by a portable instrument can find wide application as a platform for reliable and cost effective point-of-care diagnosis...
  14. ncbi request reprint BRCA2 gene mutations in Greek patients with familial breast cancer
    Athanasios Armakolas
    Laboratory of Surgical Research, A Propaedeutic Surgical Clinic, Athens Medical School, Hippokrateion Hospital, Athens, Greece
    Hum Mutat 19:81-2. 2002
    ..Our findings suggest that there is a cluster of novel mutations in exons 10 and 11 in Greek patients with familial breast cancer. These mutations appear to have a milder clinical phenotype when compared to the rest of the study group...