Research Topics
| Kalliopi N ManolaSummaryAffiliation: NCSR Demokritos Country: Greece Publications
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Detail Information
Publications
Cytogenetic abnormalities and monosomal karyotypes in children and adolescents with acute myeloid leukemia: correlations with clinical characteristics and outcomeKalliopi N Manola
Department of Cytogenetics, Laboratory of Health Physics and Enviromental Health, NCSR Demokritos Athens, Greece Electronic address
Cancer Genet 206:63-72. 2013..These data expand our knowledge by providing novel insights into the cytogenetic features and their correlations with clinical characteristics and outcomes in childhood and adolescent AML...
Isochromosome der(17)(q10)t(15;17) in acute promyelocytic leukemia resulting in an additional copy of the RARA-PML fusion gene: report of 4 cases and review of the literatureKalliopi N Manola
National Center for Scientific Research Demokritos, Athens, Greece
Acta Haematol 123:162-70. 2010..Cases of overrepresentation of the RARA-PML fusion gene and ider(17q) cases may help in elucidating the role of RARA-PML in leukemogenesis...
Cytogenetics of pediatric acute myeloid leukemiaKalliopi N Manola
Laboratory of Cytogenetics, National Center for Scientific Research, Demokritos, 15310 Aghia Paraskevi, Athens, Greece
Eur J Haematol 83:391-405. 2009....
Jumping translocations in hematological malignancies: a cytogenetic study of five casesKalliopi N Manola
Laboratory of Cytogenetics, NCSR Demokritos Athens, Greece
Cancer Genet Cytogenet 187:85-94. 2008....
Disruption of the ETV6 gene as a consequence of a rare translocation (12;12)(p13;q13) in treatment-induced acute myeloid leukemia after breast cancerKalliopi N Manola
Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, Terma Patriarchou Grigoriou and Neapoleos, Athens, Greece
Cancer Genet Cytogenet 180:37-42. 2008..To the best of our knowledge, our patient represents the first report of the rare t(12;12)(p13;q13) described in treatment-induced leukemia and the possible formation of a new fusion gene...
Leukemias associated with Turner syndrome: report of three cases and review of the literatureKalliopi N Manola
Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
Leuk Res 32:481-6. 2008....
Translocation (X;12)(p11;p13) as a sole abnormality in biphenotypic acute leukemiaKalliopi N Manola
Laboratory of Health Physics and Environmental Hygiene, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
Cancer Genet Cytogenet 173:159-63. 2007..To our knowledge, this cytogenetic aberration has not been reported previously as a sole abnormality in hematological malignancies. Its presence may suggest an important role in the pathogenesis of biphenotypic leukemia...
5'RARA submicroscopic deletion from new variant translocation involving chromosomes 15, 17, and 18, in a case of acute promyelocytic leukemiaChryssa Stavropoulou
National Center for Scientific Research Demokritos, Athens, Greece
Cancer Genet Cytogenet 182:50-5. 2008..Further cases are needed to delineate the incidence of submicroscopic deletions in APL and elucidate their prognostic impact...
Leukemic recombinations involving heterochromatin in myeloproliferative disorders with t(1;9)Constantina Sambani
Laboratory of Health Physics and Environmental Hygiene, NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
Cancer Genet Cytogenet 162:45-9. 2005..The molecular event underlying juxtaposition of satellite II of chromosome 1 and the satellite III of chromosome 9 remains to be elucidated...
Switch in X-inactivation in a JAK2 V617F-negative case of polycythemia vera with two acquired X-autosome translocationsKalliopi N Manola
Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
Leuk Res 31:1009-14. 2007..3) (second clone). The inactivation of the translocated X chromosomes could provide potential for the inactivation of the adjacent autosomal regions, resulting in epigenetic gene silencing...
A novel dic(1;10) in a patient with myelodysplastic syndromeConstantina Sambani
Laboratory of Health Physics and Environmental Hygiene, NCSR Demokritos, Athens, Greece
Cancer Genet Cytogenet 133:87-9. 2002..To our knowledge, a dicentric chromosome involving chromosomes 1 and 10 has never been described in hematological malignancies...
Translocation (6;13)(p21;q14.1) as a rare nonrandom cytogenetic abnormality in chronic lymphocytic leukemiaMaria Karakosta
Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, Athens, Greece
Cancer Genet Cytogenet 198:66-70. 2010..Further studies in more CLL patients are required to delineate the prognostic value of t(6;13)(p21;q14.1) and to identify any candidate genes with potential role in the pathogenesis of the disease...
G2-checkpoint abrogation in irradiated lymphocytes: A new cytogenetic approach to assess individual radiosensitivity and predisposition to cancerGeorgia I Terzoudi
Radiobiology and Cytogenetics, IR RP, National Center for Scientific Research NCSR Demokritos, Athens, Greece
Int J Oncol 35:1223-30. 2009..Therefore, the proposed methodology using IRP values may provide a clinically applicable predictive assay for individual radiosensitivity and predisposition to cancer...
Deletion of 5q as a rare abnormality in chronic lymphocytic leukemiaMaria Karakosta
Laboratory of Cytogenetics, NCSR Demokritos, Terma Patriarchou Grigoriou and Neapoleos, Aghia Paraskevi, Athens, Greece
Cancer Genet Cytogenet 200:175-9. 2010....
