Niki Vassilaki

Summary

Affiliation: Hellenic Pasteur Institute
Country: Greece

Publications

  1. pmc Low oxygen tension enhances hepatitis C virus replication
    N Vassilaki
    Molecular Virology, Hellenic Pasteur Institute HPI, Athens, Greece
    J Virol 87:2935-48. 2013
  2. doi request reprint The HCV ARFP/F/core+1 protein: production and functional analysis of an unconventional viral product
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece
    IUBMB Life 61:739-52. 2009
  3. doi request reprint Expression studies of the HCV-1a core+1 open reading frame in mammalian cells
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sofias Avenue, 11521 Athens, Greece
    Virus Res 133:123-35. 2008
  4. ncbi request reprint Differences in the expression of the hepatitis C virus core+1 open reading frame between a nuclear and a cytoplasmic expression system
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sofias Avenue, Athens 11521, Greece
    J Gen Virol 89:222-31. 2008
  5. ncbi request reprint Two alternative translation mechanisms are responsible for the expression of the HCV ARFP/F/core+1 coding open reading frame
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sofias Avenue, Athens, Greece 11521
    J Biol Chem 278:40503-13. 2003
  6. doi request reprint Hepatitis C virus core+1/ARF protein decreases hepcidin transcription through an AP1 binding site
    Ioly Kotta-Loizou
    Molecular Virology Laboratory, Hellenic Pasteur Institute, V Sofias Ave, 11521 Athens, Greece
    J Gen Virol 94:1528-34. 2013
  7. doi request reprint Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b
    Anissa Boumlic
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sophias Ave, 11521 Athens, Greece
    Virus Res 155:213-20. 2011
  8. pmc Expression of the novel hepatitis C virus core+1/ARF protein in the context of JFH1-based replicons
    Ioly Kotta-Loizou
    Molecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece
    J Virol 89:5164-70. 2015
  9. ncbi request reprint Expression studies of the core+1 protein of the hepatitis C virus 1a in mammalian cells. The influence of the core protein and proteasomes on the intracellular levels of core+1
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece
    FEBS J 274:4057-74. 2007
  10. ncbi request reprint Alternate translation occurs within the core coding region of the hepatitis C viral genome
    Agoritsa Varaklioti
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vassilisis Sofias Avenue, 115 21 Athens, Greece
    J Biol Chem 277:17713-21. 2002

Collaborators

Detail Information

Publications10

  1. pmc Low oxygen tension enhances hepatitis C virus replication
    N Vassilaki
    Molecular Virology, Hellenic Pasteur Institute HPI, Athens, Greece
    J Virol 87:2935-48. 2013
    ..These results provide new insights into the impact of oxygen tension on the intricate HCV-host cell interaction...
  2. doi request reprint The HCV ARFP/F/core+1 protein: production and functional analysis of an unconventional viral product
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece
    IUBMB Life 61:739-52. 2009
    ..We also provide a detailed summary of the results of patient-based research...
  3. doi request reprint Expression studies of the HCV-1a core+1 open reading frame in mammalian cells
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sofias Avenue, 11521 Athens, Greece
    Virus Res 133:123-35. 2008
    ..Furthermore, translation of core+1 ORF is not significantly affected by the presence of the HCV IRES element. The core+1/S-GFP protein is cytoplasmic and exhibits an ER distribution similar to that of the core+1/F-GFP protein...
  4. ncbi request reprint Differences in the expression of the hepatitis C virus core+1 open reading frame between a nuclear and a cytoplasmic expression system
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sofias Avenue, Athens 11521, Greece
    J Gen Virol 89:222-31. 2008
    ..Finally, although core+1 codons 85/87 is the most efficient site for internal initiation of core+1 translation, it may not be unique, as additional internal core+1 codon(s) appear to drive translation at low levels...
  5. ncbi request reprint Two alternative translation mechanisms are responsible for the expression of the HCV ARFP/F/core+1 coding open reading frame
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sofias Avenue, Athens, Greece 11521
    J Biol Chem 278:40503-13. 2003
    ..Collectively, our data suggest the existence of an alternative translation initiation mechanism that may result in the synthesis of a shorter form of the core+1 protein in transfected cells...
  6. doi request reprint Hepatitis C virus core+1/ARF protein decreases hepcidin transcription through an AP1 binding site
    Ioly Kotta-Loizou
    Molecular Virology Laboratory, Hellenic Pasteur Institute, V Sofias Ave, 11521 Athens, Greece
    J Gen Virol 94:1528-34. 2013
    ....
  7. doi request reprint Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b
    Anissa Boumlic
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vas Sophias Ave, 11521 Athens, Greece
    Virus Res 155:213-20. 2011
    ..The expression of Core+1 ORF from HCV-1b clinical isolates and the preservation of translation initiation mechanism that stimulates its expression encourage investigating the role of these proteins in HCV pathogenesis...
  8. pmc Expression of the novel hepatitis C virus core+1/ARF protein in the context of JFH1-based replicons
    Ioly Kotta-Loizou
    Molecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece
    J Virol 89:5164-70. 2015
    ..Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (short), with different kinetics. ..
  9. ncbi request reprint Expression studies of the core+1 protein of the hepatitis C virus 1a in mammalian cells. The influence of the core protein and proteasomes on the intracellular levels of core+1
    Niki Vassilaki
    Molecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece
    FEBS J 274:4057-74. 2007
    ....
  10. ncbi request reprint Alternate translation occurs within the core coding region of the hepatitis C viral genome
    Agoritsa Varaklioti
    Molecular Virology Laboratory, Hellenic Pasteur Institute, 127 Vassilisis Sofias Avenue, 115 21 Athens, Greece
    J Biol Chem 277:17713-21. 2002
    ..In conclusion, our data provide evidence for novel translation mechanisms within the core coding region and demonstrate the expression of the core+1 ORF, at least for some HCV isolates...