Smaragdi Antonopoulou

Summary

Affiliation: Harokopio University
Country: Greece

Publications

  1. ncbi request reprint Biological activity of acetylated phenolic compounds
    Elizabeth Fragopoulou
    Department of Science of Nutrition Dietetics, Harokopio University of Athens, 17671 Athens, Greece
    J Agric Food Chem 55:80-9. 2007
  2. pmc Antithrombotic and antiatherosclerotic properties of olive oil and olive pomace polar extracts in rabbits
    Nektaria Tsantila
    Laboratory of Biochemistry, Faculty of Chemistry, School of Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece
    Mediators Inflamm 2007:36204. 2007
  3. pmc Hydroxyl-platelet-activating factor exists in blood of healthy volunteers and periodontal patients
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Str, 176 71 Athens, Greece
    Mediators Inflamm 12:221-7. 2003
  4. ncbi request reprint Bioactive polar lipids from Chroococcidiopsis sp. (Cyanobacteria)
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Str, 176 71, Athens, Greece
    Comp Biochem Physiol B Biochem Mol Biol 142:269-82. 2005
  5. ncbi request reprint Characterization of bioactive glycolipids from Scytonema julianum (cyanobacteria)
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Str, 176 71 Athens, Greece
    Comp Biochem Physiol B Biochem Mol Biol 140:219-31. 2005
  6. ncbi request reprint Osmoregulatory effects of hypophysectomy and homologous prolactin replacement in hybrid striped bass
    Leslie F Jackson
    Department of Zoology, North Carolina State University, Raleigh, NC 27695 7617, USA
    Comp Biochem Physiol B Biochem Mol Biol 140:211-8. 2005
  7. ncbi request reprint Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus
    Smaragdi Antonopoulou
    Department of Science of Nutrition Dietetics, Harokopio University of Athens, Greece
    J Med Food 9:356-62. 2006
  8. pmc Isolation and structural elucidation of biologically active phospholipids from Scytonema julianum (cyanobacteria)
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Street, 17671 Athens, Greece
    Biochem J 367:287-93. 2002
  9. ncbi request reprint Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation
    Haralabos C Karantonis
    National and Kapodistrian University of Athens, Faculty of Chemistry, Panepistimioupolis, 15771 Athens, Greece
    Diabetes Res Clin Pract 72:33-41. 2006
  10. doi request reprint Baseline and 6-Week follow-up levels of PAF and activity of its metabolic enzymes in patients with heart failure and healthy volunteers--a pilot study
    Paraskevi Detopoulou
    Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
    Angiology 64:522-8. 2013

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Biological activity of acetylated phenolic compounds
    Elizabeth Fragopoulou
    Department of Science of Nutrition Dietetics, Harokopio University of Athens, 17671 Athens, Greece
    J Agric Food Chem 55:80-9. 2007
    ..In conclusion, acetylated phenolics exert the same or even higher antithrombotic activity compared to the biological activity of the initial one...
  2. pmc Antithrombotic and antiatherosclerotic properties of olive oil and olive pomace polar extracts in rabbits
    Nektaria Tsantila
    Laboratory of Biochemistry, Faculty of Chemistry, School of Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece
    Mediators Inflamm 2007:36204. 2007
    ..Specific PAF antagonists with similar in vitro and in vivo bioactivity to those that have been previously reported in OOPL exist in PPL...
  3. pmc Hydroxyl-platelet-activating factor exists in blood of healthy volunteers and periodontal patients
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Str, 176 71 Athens, Greece
    Mediators Inflamm 12:221-7. 2003
    ....
  4. ncbi request reprint Bioactive polar lipids from Chroococcidiopsis sp. (Cyanobacteria)
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Str, 176 71, Athens, Greece
    Comp Biochem Physiol B Biochem Mol Biol 142:269-82. 2005
    ..These novel bioactive polar lipids in cyanobacteria in regard to the structure and biological activity may contribute to the allergic character of cyanobacteria...
  5. ncbi request reprint Characterization of bioactive glycolipids from Scytonema julianum (cyanobacteria)
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Str, 176 71 Athens, Greece
    Comp Biochem Physiol B Biochem Mol Biol 140:219-31. 2005
    ..In addition, the identified bioactive lipids may contribute to the allergic character of cyanobacteria...
  6. ncbi request reprint Osmoregulatory effects of hypophysectomy and homologous prolactin replacement in hybrid striped bass
    Leslie F Jackson
    Department of Zoology, North Carolina State University, Raleigh, NC 27695 7617, USA
    Comp Biochem Physiol B Biochem Mol Biol 140:211-8. 2005
    ..These results indicate that PRL acts to maintain plasma osmotic and ionic balance in FW-adapted hybrid striped bass, and that this may involve downregulation of branchial Na(+),K(+)-ATPase activity...
  7. ncbi request reprint Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus
    Smaragdi Antonopoulou
    Department of Science of Nutrition Dietetics, Harokopio University of Athens, Greece
    J Med Food 9:356-62. 2006
    ..Thus the consumption of a traditional Greek Mediterranean diet even for a short period can reduce platelet activity in patients suffering from type 2 diabetes mellitus and in healthy subjects...
  8. pmc Isolation and structural elucidation of biologically active phospholipids from Scytonema julianum (cyanobacteria)
    Smaragdi Antonopoulou
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Street, 17671 Athens, Greece
    Biochem J 367:287-93. 2002
    ..In addition, Scytonema julianum contains a phosphatidylcholine (C(16:0)/(18:2)), even though bacteria in general seldom contain choline-containing phosphoacylglycerols...
  9. ncbi request reprint Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation
    Haralabos C Karantonis
    National and Kapodistrian University of Athens, Faculty of Chemistry, Panepistimioupolis, 15771 Athens, Greece
    Diabetes Res Clin Pract 72:33-41. 2006
    ....
  10. doi request reprint Baseline and 6-Week follow-up levels of PAF and activity of its metabolic enzymes in patients with heart failure and healthy volunteers--a pilot study
    Paraskevi Detopoulou
    Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
    Angiology 64:522-8. 2013
    ..004) and Lp-PLA2 (P < .001) remained elevated compared with the controls. Newly diagnosed patients with HF under drug treatment have an affected profile of PAF biosynthetic enzymes and especially lyso-PAF-AT. ..
  11. doi request reprint Platelet-activating factor and its basic metabolic enzymes in blood of naive HIV-infected patients
    Alexandros B Tsoupras
    Department of Chemistry, National and Kapodistrian University of Athens, Greece
    Angiology 63:343-52. 2012
    ....
  12. doi request reprint Effects of HAART on platelet-activating factor metabolism in naive HIV-infected patients I: study of the tenofovir-DF/emtricitabine/efavirenz HAART regimen
    Maria Chini
    3rd Internal Medicine Department Infectious Diseases Unit, Red Cross General Hospital, Athens, Greece
    AIDS Res Hum Retroviruses 28:766-75. 2012
    ....
  13. doi request reprint N-terminal ProBNP distribution and correlations with biological characteristics in apparently healthy Greek population: ATTICA study
    Elizabeth Fragopoulou
    Department of Nutrition Science and Dietetics, Harokopio University, Athens, Greece
    Angiology 61:397-404. 2010
    ..349, P < .001), and hemoglobin (rho = -.249, P < .001) values. Linear regression analysis revealed that gender is the main contributor of NT-proBNP levels, followed by age, BMI, and Cr values...
  14. ncbi request reprint In vivo antiatherogenic properties of olive oil and its constituent lipid classes in hyperlipidemic rabbits
    Haralabos C Karantonis
    Laboratory of Biochemistry, Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, Greece
    Nutr Metab Cardiovasc Dis 16:174-85. 2006
    ....
  15. ncbi request reprint Isolation and identification of hydroxyl-platelet-activating factor from natural sources
    Alexandros B Tsoupras
    Department of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, Athens, Greece
    Life Sci 79:1796-803. 2006
    ....
  16. doi request reprint Mediterranean wild plants reduce postprandial platelet aggregation in patients with metabolic syndrome
    Elizabeth Fragopoulou
    Department of Nutrition Dietetics, Harokopio University, Athens, 17671 Greece
    Metabolism 61:325-34. 2012
    ..Wild plants consumption reduced postprandial platelet hyperaggregability of metabolic syndrome patients, which may account for their healthy effects...
  17. ncbi request reprint Biologically active lipids with antiatherogenic properties from white wine and must
    Elizabeth Fragopoulou
    Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, 15771 Athens, Greece
    J Agric Food Chem 50:2684-94. 2002
    ..A significant number of biological active lipids were detected, and structural data for the most active lipids are provided...
  18. ncbi request reprint Structure elucidation of phenolic compounds from red/white wine with antiatherogenic properties
    Elizabeth Fragopoulou
    Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, Athens 15771, Greece
    Biochim Biophys Acta 1632:90-9. 2003
    ..In this study, wine compounds that antagonize PAF were isolated and purified via chromatographic procedures, and determined structurally using chemical, enzymatic and spectroscopic methods...
  19. doi request reprint Platelet activating factor (PAF) and activity of its biosynthetic and catabolic enzymes in blood and leukocytes of male patients with newly diagnosed heart failure
    Paraskevi Detopoulou
    Department of Nutrition Science Dietetics, Harokopio University, 70 E1 Venizelou Street, Athens, 17671, Greece
    Clin Biochem 42:44-9. 2009
    ..To evaluate platelet activating factor (PAF) levels, its metabolic enzymes activity and its associations with other inflammatory markers in heart failure (HF) patients...
  20. doi request reprint The association between adherence to the Mediterranean diet and adiponectin levels among healthy adults: the ATTICA study
    Elizabeth Fragopoulou
    Department of Science Nutrition Dietetics, Harokopio University, 176 71 Athens, Greece
    J Nutr Biochem 21:285-9. 2010
    ..Adherence to the Mediterranean diet was associated with an increase on adiponectin levels. This finding may partially explain beneficial effects of this traditional healthy diet on the cardiovascular system...
  21. pmc In vivo effect of two first-line ART regimens on inflammatory mediators in male HIV patients
    Vasiliki D Papakonstantinou
    Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, 15771 Athens, Greece
    Lipids Health Dis 13:90. 2014
    ..The purpose of this study is to define the in vivo effect of two first-line ART regimens on certain inflammatory mediators in male HIV patients...
  22. pmc Lipoprotein-associated phospholipase A2 (Lp-PLA2) activity, platelet-activating factor acetylhydrolase (PAF-AH) in leukocytes and body composition in healthy adults
    Paraskevi Detopoulou
    Department of Nutrition Dietetics, Harokopio University, Athens, Greece
    Lipids Health Dis 8:19. 2009
    ..Body composition was assessed with dual-energy X-ray absorptiometry, while anthropometrical indices were also measured. The activity of Lp-PLA2 and levels of lipid and glycemic parameters were determined in fasting samples...
  23. doi request reprint In vitro and in vivo effects of statins on platelet-activating factor and its metabolism
    Nektaria Tsantila
    Laboratory of Biochemistry, Faculty of Chemistry, National and Kapodistrian University, Athens, Greece
    Angiology 62:209-18. 2011
    ..This suggests that these simvastatin-dependent effects are independent of its lactone ring. These new actions of statins should be further studied in PAF-implicated pathological conditions such as CVD, cancer, and renal disease...
  24. ncbi request reprint Anti-platelet-activating factor effects of highly active antiretroviral therapy (HAART): a new insight in the drug therapy of HIV infection?
    Alexandros B Tsoupras
    University of Athens, Faculty of Chemistry, Athens, Greece
    AIDS Res Hum Retroviruses 24:1079-86. 2008
    ..These promising results need to be further studied and confirmed by additional in vivo tests in order to optimize HAART efficacy...
  25. ncbi request reprint Antithrombotic lipid minor constituents from vegetable oils. Comparison between olive oils and others
    Haralabos C Karantonis
    Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, 15771 Athens, Greece
    J Agric Food Chem 50:1150-60. 2002
    ..Because it has already been reported that PAF plays a pivotal role in atherogenesis, the existence of PAF agonists and antagonists in vegetable oils may explain their protective role against atherosclerosis...
  26. doi request reprint Interleukin-1beta stimulates platelet-activating factor production in U-937 cells modulating both its biosynthetic and catabolic enzymes
    Ioanna C Vlachogianni
    Faculty of Chemistry, National and Kapodistrian University, Athens, Greece
    Cytokine 63:97-104. 2013
    ..The regulation of PAF's enzymatic machinery under inflammatory conditions is more complicated than we thought to be...
  27. doi request reprint PAF and its metabolic enzymes in healthy volunteers: interrelations and correlations with basic characteristics
    Paraskevi Detopoulou
    Department of Nutrition Dietetics, Harokopio University, 70 El Venizelou Street, 17671, Athens, Greece
    Prostaglandins Other Lipid Mediat 97:43-9. 2012
    ..The present study underlines the complexity of PAF's metabolism determinants...
  28. ncbi request reprint Synthesis and biological evaluation of novel steroid-modified ether phospholipids
    Haralabos C Karantonis
    Laboratory of Biochemistry, Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, GR 157 71 Athens, Greece
    Chem Phys Lipids 138:12-9. 2005
    ..These two novel compounds exhibit marked chemical and biological similarities to their endogenous prototype and they antagonize it being less active in inducing washed platelet aggregation through PAF receptors...
  29. doi request reprint PAF effects on MCP-1 and IL-6 secretion in U-937 monocytes in comparison with oxLDL and IL-1β effects
    Sophia N Verouti
    Faculty of Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis, 15771 Athens, Greece
    Atherosclerosis 219:519-25. 2011
    ..To study the effects of PAF, in comparison with oxLDL and IL-1β on MCP-1 and IL-6 secretion from U-937 monocytes and to investigate the mechanism of its action...
  30. doi request reprint Chemical composition of Greek avgotaracho prepared from mullet (Mugil cephalus): nutritional and health benefits
    Nick Kalogeropoulos
    Department of Science of Dietetics Nutrition, Harokopio University, 70 El Venizelou Street, 176 71 Athens, Greece
    J Agric Food Chem 56:5916-25. 2008
    ....
  31. doi request reprint Acute resistance exercise attenuates fasting and postprandial triglyceridemia in women by reducing triglyceride concentrations in triglyceride-rich lipoproteins
    Evelin Zotou
    Department of Nutrition and Dietetics, Harokopio University, 70 El Venizelou Avenue, 17671, Athens, Greece
    Eur J Appl Physiol 110:869-74. 2010
    ..60). We conclude that a single bout of resistance exercise attenuates fasting and postprandial triglyceridemia in women by reducing TRL-TG concentrations...
  32. pmc Characterization of the de novo biosynthetic enzyme of platelet activating factor, DDT-insensitive cholinephosphotransferase, of human mesangial cells
    Alexandros Basilios Tsoupras
    Faculty of Chemistry, School of Sciences, National and Kapodistrian University of Athens, Panepistimioupolis, 15771 Athens, Greece
    Mediators Inflamm 2007:27683. 2007
    ..The results indicated that the above compounds can influence PAF-CPT activity of HMC...
  33. doi request reprint Platelet activating factor in heart failure: potential role in disease progression and novel target for therapy
    Paraskevi Detopoulou
    Department of Nutrition, General Hospital Korgialenio Benakio, Athanasaki 1, Athens, Greece
    Curr Heart Fail Rep 10:122-9. 2013
    ..In the present review the role of PAF in HF will be thoroughly presented along with the relevant data on PAF enzymes and the potential role of PAF metabolic circuit as a novel pharmacological target...
  34. ncbi request reprint Serum total selenium status in Greek adults and its relation to age. The ATTICA study cohort
    Sophia Letsiou
    Department of Science of Nutrition Dietetics, Harokopio University, El Venizelou 70, Athens, Greece
    Biol Trace Elem Res 128:8-17. 2009
    ..This result may indicate that other factors such as selenium distribution as well as retention may be affecting the relationship between serum selenium and age...
  35. doi request reprint Oral supplementation with L-aspartate and L-glutamate inhibits atherogenesis and fatty liver disease in cholesterol-fed rabbit
    Amalia E Yanni
    Department of Dietetics and Nutrition, Harokopio University of Athens, 70 El Venizelou Avenue, 17671, Athens, Greece
    Amino Acids 38:1323-31. 2010
    ..The beneficial effects of dicarboxylic amino acids reflect the limited elevation of serum gamma-GT activity...
  36. ncbi request reprint Effects of eccentric exercise-induced muscle injury on blood levels of platelet activating factor (PAF) and other inflammatory markers
    George A Milias
    Department of Science of Nutrition Dietetics, Harokopio University of Athens, 70 El Venizelou Str, 176 71, Athens, Greece
    Eur J Appl Physiol 95:504-13. 2005
    ..e. CK, LDH, FANG and CIRC (all P's<0.05). Our findings may imply a role for PAF in the mechanism of eccentric exercise induced muscle damage...
  37. ncbi request reprint Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study
    Paraskevi Detopoulou
    Department of Nutrition Science Dietetics, Harokopio University, Athens, Greece
    Am J Clin Nutr 87:424-30. 2008
    ..Choline and betaine are found in a variety of plant and animal foods and were recently shown to be associated with decreased homocysteine concentrations...
  38. ncbi request reprint Platelet-activating factor (PAF) increase intracellular lipid accumulation by increasing both LDL and scavenger receptors in human mesangial cells
    Elizabeth Fragopoulou
    Faculty of Chemistry, National and Kapodistrian University of Athens, Athens, Greece
    J Lab Clin Med 147:281-9. 2006
    ..These results suggest that PAF has a potential role in lipid mediated renal injury...
  39. ncbi request reprint Is platelet-activating factor produced during hemodialysis with AN-69 polyacrylonitrile membrane?
    Christos Iatrou
    Department of Nephrology, General Hospital of Nikaias Pereaus, Athens, Greece
    Nephron 91:86-93. 2002
    ....
  40. doi request reprint Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention
    Maria Petrogianni
    1 Department of Nutrition and Dietetics, Harokopio University, 70 Elefteriou Venizelou Street, 17671 Athens, Greece
    Public Health Nutr 17:440-9. 2014
    ..The current study aimed to evaluate the effect of fortified milk combined with a lifestyle and counselling programme on several CVD risk factors after a 3-month dietary intervention...
  41. doi request reprint Mineral intake
    Maria G Stathopoulou
    Department of Dietetics and Nutritional Science, Harokopio University of Athens, Athens, Greece
    Prog Mol Biol Transl Sci 108:201-36. 2012
    ..Also, these elements are associated with genetic diseases and are known to interact with genetic variants in a wide range of diseases...
  42. doi request reprint Intravenous infusion of PAF affects ovulation, fertilization and preimplantation embryonic development in NZB x NZW F1 hybrid mice
    Maria Sakellariou
    1st Department of Obstetrics and Gynecology, Athens University Medical School, Athens, Greece
    Prostaglandins Other Lipid Mediat 85:125-33. 2008
    ..Our data show that the effect of PAF on early stages of embryo development in vitro is dependent on its way of administration, on the concentrations used as well as on the time PAF is injected...
  43. pmc Association of the +45T>G and +276G>T polymorphisms in the adiponectin gene with insulin resistance in nondiabetic Greek women
    Labros Melistas
    Departments of, Nutrition and Dietetics Home Economics, Harokopio University of Athens, El Venizelou 70, 17671 Athens, Greece
    Eur J Endocrinol 161:845-52. 2009
    ....
  44. ncbi request reprint Effect of fast-food Mediterranean-type diet on human plasma oxidation
    Pantelis Aronis
    Department of Chemistry, University of Ioannina, Ioannina, Greece
    J Med Food 10:511-20. 2007
    ..Therefore consumption of a fast food Mediterranean-type diet should contribute to prevention against cardiovascular diseases...