Research Topics
Species | Marina EconomouSummaryAffiliation: Aristotle University of Thessaloniki Country: Greece Publications
| Collaborators
|
Detail Information
Publications
Brain and Spinal MR Imaging Findings in Mucopolysaccharidoses: A ReviewD I Zafeiriou
First Department of Paediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
AJNR Am J Neuroradiol 34:5-13. 2013..Finally, recent data concerning MR spectroscopy studies in MPS are also critically discussed...- Pontocerebellar hypoplasia in extreme prematurity: clinical and neuroimaging findingsDimitrios I Zafeiriou
First Department of Pediatrics, Aristotle University, Hippokratio General Hospital, Thessaloniki, Greece
Pediatr Neurol 48:48-51. 2013..All patients exhibited developmental delays of variable degrees. One patient died at age 7.5 years. The possible etiopathogenesis, presentations, sequelae, and differential diagnoses of acquired pontocerebellar hypoplasia are discussed... 
Cerebellar agenesis and diabetes insipidusD I Zafeiriou
1st Department of Paediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
Neuropediatrics 35:364-7. 2004..A literature review disclosed only a few patients with CA (defined in a strict sense) diagnosed in vivo by MRI. It is questionable whether asymptomatic CA occurs...- Neurological complications in beta-thalassemiaDimitrios I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece
Brain Dev 28:477-81. 2006.... - Congenital Horner's syndrome associated with cervical neuroblastomaDimitrios I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece
Eur J Paediatr Neurol 10:90-2. 2006..Although the association of Horner's syndrome with acquired neuroblastoma is well-known and of value in early diagnosing of such a tumor, it can also be a presenting or accompanying sign in rare cases of congenital neuroblastoma... - Childhood autism and associated comorbiditiesDimitrios I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Egnatia St 106, 54622 Thessaloniki, Greece
Brain Dev 29:257-72. 2007.... - 3-Hydroxy-3-methylglutaryl coenzyme a lyase deficiency with reversible white matter changes after treatmentDimitrios I Zafeiriou
1st Department of Pediatrics, Aristotle University, Thessaloniki, Greece
Pediatr Neurol 37:47-50. 2007..He demonstrated reversible white matter changes on serial brain magnetic resonance imaging, together with clinical normalization, after initiation of a leucine-restricted diet... - Ethylmalonic encephalopathy: clinical and biochemical observationsD I Zafeiriou
Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
Neuropediatrics 38:78-82. 2007..On repeat MRI, a significant deterioration was seen, correlating well with the clinical deterioration of the patient... - Serial magnetic resonance imaging and neurophysiological studies in multiple sulphatase deficiencyDimitrios I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Greece
Eur J Paediatr Neurol 12:190-4. 2008.... - L-2-Hydroxyglutaric aciduria presenting with severe autistic featuresD I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
Brain Dev 30:305-7. 2008..Autism has not so far been described in L-2-HGA and may be considered as an additional feature of the phenotypic spectrum... - Obstetrical brachial plexus palsyDimitrios I Zafeiriou
First Department of Pediatrics, Aristotle University, Thessaloniki, Greece
Pediatr Neurol 38:235-42. 2008..This review focuses on emerging data relating to obstetrical brachial plexus palsy and discusses the present controversies regarding natural history, prognosis, and treatment in infants with brachial plexus birth palsies... - Episodic ataxia type 2 showing ictal hyperhidrosis with hypothermia and interictal chronic diarrhea due to a novel CACNA1A mutationD I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Egnatia St 106, 54622 Thessaloniki, Greece
Eur J Paediatr Neurol 13:191-3. 2009..Both ictal hyperhidrosis and interictal diarrhea ameliorated upon acetazolamide intake, the typical treatment for EA2. The significance of these findings is discussed and the phenotype correlated to previously reported cases... - MR spectroscopy and serial magnetic resonance imaging in a patient with mitochondrial cystic leukoencephalopathy due to complex I deficiency and NDUFV1 mutations and mild clinical courseD I Zafeiriou
Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
Neuropediatrics 39:172-5. 2008..In conclusion, diffuse white matter changes on MRI are compatible with mitochondrial encephalopathy and not necessarily associated with a severe clinical course... - Tyrosine hydroxylase deficiency with severe clinical courseD I Zafeiriou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
Mol Genet Metab 97:18-20. 2009..He is the third Greek patient with TH deficiency to be reported. Since all three patients carry the same pathogenetic mutation, a founder effect is suspected... - Diverse clinical and genetic aspects of craniofrontonasal syndromeDimitrios I Zafeiriou
First Department of Pediatrics, Ippokratio Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
Pediatr Neurol 44:83-7. 2011..We review the literature on this genetic paradox, and discuss the pattern of inheritance and genetic counseling... - Seroepidemiology of rubella in northern GreeceG Gioula
Microbiology Department B, Medical School, Aristotelian University of Thessaloniki, Egnatia Street 106, 54622 Thessaloniki, Greece
Eur J Clin Microbiol Infect Dis 23:631-3. 2004..6% of the study population, 10.3% were susceptible to rubella and only 16.4% were vaccinated. The results indicate a comprehensive policy is still needed in order to eliminate rubella and congenital rubella syndrome in Greece... - Central nervous system abnormalities in asymptomatic young patients with Sbeta-thalassemiaDimitrios I Zafeiriou
First Pediatric Clinic, Aristotle University of Thessaloniki, Greece
Ann Neurol 55:835-9. 2004..International collaboration is needed to establish the risk factors for central nervous system sequelae in patients with sickle cell disease, including Sbeta-thalassemia, leading to evidence-based prevention... - Plantar response profile of high-risk infants at one year of lifeD I Zafeiriou
First Pediatric Clinic, Aristotle University of Thessaloniki, Greece
J Child Neurol 14:514-7. 1999..The combined extensor plantar response remains a reliable prognostic clinical tool that contributes to an earlier diagnosis of spastic cerebral palsy as early as the first month of life... - Utility of brainstem auditory evoked potentials in children with spastic cerebral palsyD I Zafeiriou
First Pediatric Clinic, Aristotle University of Thessaloniki, Greece
Acta Paediatr 89:194-7. 2000..BAEP testing should be incorporated into the diagnostic plan of all children with spastic CP newly referred to neurodevelopmental centres... - Characteristics and prognosis of epilepsy in children with cerebral palsyD I Zafeiriou
First Pediatric Clinic, Aristotle University of Thessaloniki, Greece
J Child Neurol 14:289-94. 1999.... - Clinical features, laboratory findings and differential diagnosis of benign acute childhood myositisD I Zafeiriou
1st Pediatric Clinic, Aristotle University of Thessaloniki, Greece
Acta Paediatr 89:1493-4. 2000..All patients made a rapid recovery within one week. We conclude that BACM should be encountered among the main causes of sudden-onset gait abnormality in young children... - L-2-Hydroxyglutaric aciduria presenting as status epilepticusD I Zafeiriou
Developmental Center A Fokas, 1st Pediatric Clinic, Aristotle University of Thessaloniki, Thessaloniki, Greece
Brain Dev 23:255-7. 2001..Although rare, epileptic seizures or even status epilepticus can be among the presenting symptoms in organic acidurias with a slow course, such as L-2-HGA... - Atypical and variable clinical presentation of glutaric aciduria type ID I Zafeiriou
First Paediatric Clinic, Aristotle University of Thessaloniki, Greece
Neuropediatrics 31:303-6. 2000..Asymptomatic siblings of GA I patients should always be investigated, and molecular studies may be useful for confirming the diagnosis, particularly when the presentation is atypical... - Serial magnetic resonance imaging findings in mucopolysaccharidosis IIIB (Sanfilippo's syndrome B)D I Zafeiriou
First Pediatric Clinic, University of Thessaloniki, Egnatia Street 106, 54622, Thessaloniki, Greece
Brain Dev 23:385-9. 2001..Although the combination of the above MRI findings is highly suggestive of a MPS, they carry a little predictive value in the different clinical stages of MPS IIIB... - Using postural reactions as a screening test to identify high-risk infants for cerebral palsy: a prospective studyD I Zafeiriou
1st Pediatric Clinic, Aristotle University of Thessaloniki, Greece
Brain Dev 20:307-11. 1998..We conclude that the examination of PR is a useful quantitative and qualitative diagnostic screening tool for high-risk infants from the 1st month of life... - Familial moyamoya disease in a Greek familyDimitrios I Zafeiriou
1st Paediatric Klinic, Aristotle University, Thessaloniki, Greece
Brain Dev 25:288-90. 2003..Linkage analysis of the whole family was consistent with linkage to the region 3p24-26, as previously reported in other familial Japanese M-M cases... - Reflex myoclonic epilepsy in infancy: a benign age-dependent idiopathic startle epilepsyDimitrios Zafeiriou
1st Pediatric Clinic, Aristotle University of Thessaloniki, Greece
Epileptic Disord 5:121-2. 2003..RMEI should be considered as an age-dependent, idiopathic, generalized epileptic syndrome with an apparently good prognosis[Published with video sequences]... - Clinical and neurophysiological characteristics of congenital myasthenic syndromes presenting in early infancyDimitrios I Zafeiriou
Department of Neurology, Great Ormond Street Hospital, London, UK
Brain Dev 26:47-52. 2004..The recognition of specific clinical constellations combined with a search for aetiology at a molecular level will enable the further characterisation of subgroups of CMS... - Single dose immunoglobulin therapy for childhood Guillain-Barré syndromeD I Zafeiriou
1st Pediatric Clinic, Aristotelian University of Thessaloniki, Greece
Brain Dev 19:323-5. 1997..The most beneficial IVIG dose regimen remains to be determined by controlled trials... - Protracted course of N-acetylaspartic aciduria in two non-Jewish siblings: identical clinical and magnetic resonance imaging findingsD I Zafeiriou
First Pediatric Clinic, Aristotle University of Thessaloniki, Greece
Brain Dev 21:205-8. 1999.... - Fok-I polymorphism of vitamin D receptor gene and the presence of renal dysfunction in patients with β-thalassemia majorMeropi Dimitriadou
First Paediatric Department, Aristotle University of Thessaloniki, Greece
Pediatr Hematol Oncol 28:509-16. 2011..29% and 31.25%, respectively, P = .02). Further studies are needed to confirm these preliminary results and elucidate the possible mechanisms involved... - Subclinical central nervous system involvement and thrombophilic status in young thalassemia intermedia patients of Greek originAikaterini Teli
Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece
Blood Coagul Fibrinolysis 23:195-202. 2012..Additionally, they demonstrate subclinical CNS involvement starting at childhood. For such involvement detection, in addition to neuroimaging, neurophysiological and neuropsychological evaluation is warranted... - Renal dysfunction in patients with beta-thalassemia major receiving iron chelation therapy either with deferoxamine and deferiprone or with deferasiroxMarina Economou
First Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece
Acta Haematol 123:148-52. 2010..Further studies are needed in order to investigate the role of new chelators in tubular function parameters... - Elevated serum parathormone levels are associated with myocardial iron overload in patients with beta-thalassaemia majorMeropi Dimitriadou
1st Paediatric Department, Aristotle University of Thessaloniki, Greece
Eur J Haematol 84:64-71. 2010..The aim of this study was to measure parathormone (PTH) and metabolites of vitamin D and consequently to investigate whether these parameters predispose to myocardial iron overload in patients with beta-thalassaemia major... - Neurophysiologic and intellectual evaluation of beta-thalassemia patientsMarina Economou
1st Department of Pediatrics, Aristotle University of Thessaloniki, and Thalassemia Unit, Hippokratio General Hospital, Thessaloniki, Egnatia St. 106, Thessaloniki 546 22, Greece
Brain Dev 28:14-8. 2006..Factors associated with chronic illness, rather than the disease per se, could play a potential role in the development of cognitive dysfunction in beta-thalassemia patients... - Fok-I gene polymorphism of vitamin D receptor in patients with beta-thalassemia major and its effect on vitamin D statusMeropi Dimitriadou
1st Paediatric Department, Medical School, Aristotle University of Thessaloniki, 21 Athanasiou Soulioti str, Thessaloniki, Greece
Hematology 16:54-8. 2011..Further studies are required to assess the genetic contribution to the regulation of vitamin D metabolites in the serum of patients with beta-thalassemia major... - FcγRIIa and FcγRIIIa polymorphisms in childhood primary immune thrombocytopenia: implications for disease pathogenesis and outcomeAndromachi Papagianni
1st Paediatric Department, Ippokration General Hospital, Thessaloniki, Greece
Blood Coagul Fibrinolysis 24:35-9. 2013..High-affinity FcγRIIIa variant (158 V) is possibly implicated in disease susceptibility, but neither of the two Fcγ receptor single-nucleotide polymorphisms seem to have any impact on chronicity or therapeutic effect of IVIG... - Immune and neural status of thalassemic patients receiving deferiprone or combined deferiprone and deferoxamine chelation treatmentNatalie Tourkantoni
Thalassaemia Unit, Hippokratio General Hospital, Thessaloniki, Greece
Hemoglobin 32:35-40. 2008..Further advantages have been identified for the oral use of L1 and its combination with DFO, including synergistic efficacy and lower dosing with limited toxicity... - MYH9-related disorders: report on a patient of Greek origin presenting with macroscopic hematuria and presenile cataract, caused by an R1165C mutationMarina Economou
1st Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece
J Pediatr Hematol Oncol 34:412-5. 2012..The p.R1165C mutation is one of the MYH9 alterations whose prognostic significance is still poorly defined. Thus, the patients described add to the limited existing data on the MYH9 mutations and their resultant phenotypes... - The effect of dietary habits and socioeconomic status on the prevalence of iron deficiency in children of northern GreeceNikolaos Gompakis
1st Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece
Acta Haematol 117:200-4. 2007..Despite encouraging reports concerning the declining prevalence of iron deficiency, this easily preventable disorder is still an existing problem in presumably developed regions... - Bone status of children with hemophilia A assessed with quantitative ultrasound sonography (QUS) and dual energy X-ray absorptiometry (DXA)Athanasios Christoforidis
1st Paediatric Department, Aristotle University, Thessaloniki, Greece
J Pediatr Hematol Oncol 32:e259-63. 2010..262). In conclusion, our study showed that only a small number of children and young adults with hemophilia have impaired bone properties as assessed both by DXA and QUS; no correlation was observed between these 2 methods... - Restrictive pulmonary dysfunction and its predictors in young patients with β-thalassaemia majorEvangelia Bourli
First Paediatric Department, Aristotle University of Thessaloniki, Thessaloniki, Greece
Pediatr Pulmonol 47:801-7. 2012..Pulmonary dysfunction represents one of the most undervalued and less recognized complications in patients with β-thalassaemia... - Self-mutilation and mental retardation: clues to congenital insensitivity to pain with anhidrosisDimitrios I Zafeiriou
1st Pediatric Clinic, Aristotle University of Thessaloniki, 54622 Thessaloniki, Greece
J Pediatr 144:284. 2004 - MRI assessment of liver iron content in thalassamic patients with three different protocols: comparisons and correlationsAthanasios Christoforidis
Thalassaemia Unit, Ippokratio Hospital, Thessaloniki, Greece
Eur J Haematol 82:388-92. 2009..No correlation occurred between each liver MRI parameter and myocardial R2* values. Finally, we managed to provide formulae for equating values obtaining with any of these three MRI methods... - Standard-dose intravenous anti-D immunoglobulin versus intravenous immunoglobulin in the treatment of newly diagnosed childhood primary immune thrombocytopeniaAndromachi Papagianni
First Pediatric Department of Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece
J Pediatr Hematol Oncol 33:265-9. 2011.... - Congenital erythrocytosis with increased erythropoietin levelMiranda Athanasiou-Metaxa
First Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece
J Pediatr Hematol Oncol 24:234-6. 2002..Although such a finding is considered typical of polycythemia vera, the diagnostic criteria of this myeloproliferative disorder were not met... - Evaluation of iron overload in beta-thalassemia patients using magnetic resonance imagingVassilios Perifanis
Thalassemia Unit, Hippokration General Hospital, Thalitos, Thessaloniki, Greece
Hemoglobin 28:45-9. 2004 - Haplotype analysis suggests a single Balkan origin for the Gaucher disease [D409H;H255Q] double mutant alleleRaul Santamaria
Departament de Genetica, Universitat de Barcelona, Barcelona, Spain
Hum Mutat 29:E58-67. 2008..The results of the 37 chromosomes analysed showed that most of them share a common haplotype and are consistent with a single origin in the Balkans and the Adriatic area of Italy for the [D409H;H255Q] allele...