M E Falagas

Summary

Affiliation: Alfa Institute of Biomedical Sciences
Country: Greece

Publications

  1. ncbi request reprint Linezolid for the treatment of patients with endocarditis: a systematic review of the published evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS Athens, Greece
    J Antimicrob Chemother 58:273-80. 2006
  2. pmc A bibliometric analysis by geographic area of published research in several biomedical fields, 1995-2003
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    CMAJ 175:1389-90. 2006
  3. doi request reprint Inhaled colistin for the treatment of tracheobronchitis and pneumonia in critically ill children without cystic fibrosis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Pediatr Pulmonol 45:1135-40. 2010
  4. ncbi request reprint Attributable mortality of candidemia: a systematic review of matched cohort and case-control studies
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, Athens, Marousi, 15123, Greece
    Eur J Clin Microbiol Infect Dis 25:419-25. 2006
  5. doi request reprint Therapeutic options for Stenotrophomonas maltophilia infections beyond co-trimoxazole: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Antimicrob Chemother 62:889-94. 2008
  6. doi request reprint Pandemic A(H1N1) 2009 influenza: review of the Southern Hemisphere experience
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Epidemiol Infect 139:27-40. 2011
  7. ncbi request reprint Psychosocial factors and susceptibility to or outcome of acute respiratory tract infections
    M E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Int J Tuberc Lung Dis 14:141-8. 2010
  8. doi request reprint Fosfomycin for the treatment of infections caused by multidrug-resistant non-fermenting Gram-negative bacilli: a systematic review of microbiological, animal and clinical studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Antimicrob Agents 34:111-20. 2009
  9. ncbi request reprint Arrhythmias associated with fluoroquinolone therapy
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Int J Antimicrob Agents 29:374-9. 2007
  10. ncbi request reprint Comparison of SCImago journal rank indicator with journal impact factor
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    FASEB J 22:2623-8. 2008

Collaborators

Detail Information

Publications218 found, 100 shown here

  1. ncbi request reprint Linezolid for the treatment of patients with endocarditis: a systematic review of the published evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS Athens, Greece
    J Antimicrob Chemother 58:273-80. 2006
    ..However, the drug is sometimes used for the treatment of patients with endocarditis due to Gram-positive cocci resistant to other antibiotics...
  2. pmc A bibliometric analysis by geographic area of published research in several biomedical fields, 1995-2003
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    CMAJ 175:1389-90. 2006
    ..However, after adjustments for GDP, Canada ranked first, with the United States and Oceania following closely behind. All of the developing regions had only small research contributions in all of the biomedical fields examined...
  3. doi request reprint Inhaled colistin for the treatment of tracheobronchitis and pneumonia in critically ill children without cystic fibrosis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Pediatr Pulmonol 45:1135-40. 2010
    ..Further studies are needed to clarify further the role of inhaled colistin in pediatric critically ill patients without cystic fibrosis...
  4. ncbi request reprint Attributable mortality of candidemia: a systematic review of matched cohort and case-control studies
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, Athens, Marousi, 15123, Greece
    Eur J Clin Microbiol Infect Dis 25:419-25. 2006
    ....
  5. doi request reprint Therapeutic options for Stenotrophomonas maltophilia infections beyond co-trimoxazole: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Antimicrob Chemother 62:889-94. 2008
    ..We sought to evaluate the available clinical evidence regarding potentially effective alternative antibiotics for the treatment of S. maltophilia infections...
  6. doi request reprint Pandemic A(H1N1) 2009 influenza: review of the Southern Hemisphere experience
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Epidemiol Infect 139:27-40. 2011
    ..Pregnant women represented 7·4-9·1% and 7·1-9·1% of unselected laboratory-confirmed cases and of those admitted to ICUs, respectively. Obesity and morbid obesity were more commonly reported as the level of healthcare increased...
  7. ncbi request reprint Psychosocial factors and susceptibility to or outcome of acute respiratory tract infections
    M E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Int J Tuberc Lung Dis 14:141-8. 2010
    ..To perform a systematic review of the literature to assess the possible effect that psychosocial variables may have on the susceptibility and/or outcome of acute respiratory tract infections (ARTIs)...
  8. doi request reprint Fosfomycin for the treatment of infections caused by multidrug-resistant non-fermenting Gram-negative bacilli: a systematic review of microbiological, animal and clinical studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Antimicrob Agents 34:111-20. 2009
    ..In conclusion, fosfomycin could have a role as a therapeutic option against MDR P. aeruginosa infections. Further research is needed to clarify the potential utility of this agent...
  9. ncbi request reprint Arrhythmias associated with fluoroquinolone therapy
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Int J Antimicrob Agents 29:374-9. 2007
    ..The overall risk of Tdp is small with the use of fluoroquinolones. Clinicians can minimise that risk by avoiding prescriptions of multiple medications associated with QT interval prolongation, especially in high-risk patients...
  10. ncbi request reprint Comparison of SCImago journal rank indicator with journal impact factor
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    FASEB J 22:2623-8. 2008
    ....
  11. doi request reprint Antimicrobial susceptibility of multidrug-resistant Gram negative bacteria to fosfomycin
    M E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Eur J Clin Microbiol Infect Dis 27:439-43. 2008
    ..pneumoniae and, secondly, P. aeruginosa...
  12. ncbi request reprint Comparison of the distribution of citations received by articles published in high, moderate, and low impact factor journals in clinical medicine
    M E Falagas
    Department of Medicine, Alfa Institute of Biomedical Sciences, Athens, Greece
    Intern Med J 40:587-91. 2010
    ..We sought to further investigate this issue in general and internal medicine journals...
  13. ncbi request reprint Effectiveness and nephrotoxicity of colistin monotherapy vs. colistin-meropenem combination therapy for multidrug-resistant Gram-negative bacterial infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Clin Microbiol Infect 12:1227-30. 2006
    ..21/57 (36.8%) deaths, p 0.007), even after adjusting for the variables for which significant differences were found...
  14. ncbi request reprint Probiotics for prevention of recurrent urinary tract infections in women: a review of the evidence from microbiological and clinical studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Drugs 66:1253-61. 2006
    ..However, further research is needed to confirm these results before the widespread use of probiotics for this indication can be recommended...
  15. doi request reprint Susceptibility of Gram-negative bacteria to isepamicin: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Expert Rev Anti Infect Ther 10:207-18. 2012
    ..In conclusion, isepamicin might be active in vitro against Gram-negative bacteria with resistance to amikacin and other aminoglycosides...
  16. ncbi request reprint Tuberculosis in patients with systemic rheumatic or pulmonary diseases treated with glucocorticosteroids and the preventive role of isoniazid: a review of the available evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, Marousi 151 23, Athens, Greece
    Int J Antimicrob Agents 30:477-86. 2007
    ....
  17. ncbi request reprint Risk factors for the isolation of multi-drug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa: a systematic review of the literature
    M E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Hosp Infect 64:7-15. 2006
    ..baumannii and P. aeruginosa suggests that a separate outbreak investigation should be performed in each hospital setting. The development of innovative control strategies is needed in order to limit the spread of these pathogens...
  18. doi request reprint β-D-glucan assay for the diagnosis of invasive fungal infections: a meta-analysis
    Drosos E Karageorgopoulos
    Alfa Institute of Biomedical Sciences, Laikon General Hospital, Athens, Greece
    Clin Infect Dis 52:750-70. 2011
    ..BDG has good diagnostic accuracy for distinguishing proven or probable IFIs from no IFIs. It can be useful in clinical practice, if implemented in the proper setting and interpreted after consideration of its limitations...
  19. ncbi request reprint Clinical decision-making based on findings presented in conference abstracts: is it safe for our patients?
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Eur Heart J 27:2038-9. 2006
    ..Instead, we believe that we better serve our patients by waiting at least for the evaluation of potential scientific advances by rigorous peer review...
  20. ncbi request reprint Polymyxins: old antibiotics are back
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Lancet 367:633-4. 2006
  21. ncbi request reprint The risk of using the Internet as reference resource: a comparative study
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Med Inform 77:280-6. 2008
    ..We sought to examine the frequency and the specific problems encountered in accessing Internet references in two leading medical journals during the last 3 years...
  22. ncbi request reprint Effectiveness and safety of high-dose tigecycline-containing regimens for the treatment of severe bacterial infections
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece Department of Internal Medicine Infectious Diseases, Mitera Hospital, Hygeia group, Athens, Greece Tufts University School of Medicine, Boston, MA, USA Electronic address
    Int J Antimicrob Agents 44:1-7. 2014
    ..Pharmacokinetic/pharmacodynamic properties of tigecycline suggest that high-dose regimens may be more effective than low-dose regimens. Candidates for administration of high-dose tigecycline should be also defined. ..
  23. doi request reprint Antimicrobial susceptibility of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Enterobacteriaceae isolates to fosfomycin
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:240-3. 2010
    ..We suggest further evaluation of the potential clinical utility of fosfomycin against infections caused by these pathogens...
  24. pmc Risk factors for isolation of strains susceptible only to polymyxin among patients with Pseudomonas aeruginosa bacteremia
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Antimicrob Agents Chemother 50:2541-3. 2006
    ..The multivariable analysis showed that exposure to carbapenems was associated with the development of P. aeruginosa bacteremia susceptible only to polymyxin (odds ratio, 9.0; 95% confidence interval, 2.4 to 34.3; P = 0.001)...
  25. ncbi request reprint Factors associated with suboptimal compliance to vaccinations in children in developed countries: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Curr Med Res Opin 24:1719-41. 2008
    ..The suboptimal compliance to vaccinations continues to be a major public health problem...
  26. ncbi request reprint Mesh-related infections after pelvic organ prolapse repair surgery
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Eur J Obstet Gynecol Reprod Biol 134:147-56. 2007
    ..Although the use of vaginal meshes has become a new effective method of pelvic organ prolapse surgery clinicians should be aware of the various post-operative complications, including mesh-related infections...
  27. doi request reprint Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis
    Evridiki K Vouloumanou
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Intensive Care Med 37:747-62. 2011
    ..To assess the value of serum procalcitonin (PCT) for the differentiation between patients with and without neonatal sepsis...
  28. ncbi request reprint Oral rifampin for eradication of Staphylococcus aureus carriage from healthy and sick populations: a systematic review of the evidence from comparative trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Am J Infect Control 35:106-14. 2007
    ..Rifampin has been used for the eradication of Staphylococcus aureus (S. aureus) colonization in various populations of healthy and sick people...
  29. doi request reprint Tigecycline for the treatment of patients with community-acquired pneumonia requiring hospitalization
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 15123 Marousi, Athens, Greece
    Expert Rev Anti Infect Ther 7:913-23. 2009
    ..In addition, in a recent study concerns were expressed about the efficacy of tigecycline in the lungs using the current dosage. More data are needed about the pharmacokinetics of tigecycline in the lungs and its efficacy in severe CAP...
  30. ncbi request reprint Cure of persistent, post-appendectomy Klebsiella pneumoniae septicaemia with continuous intravenous administration of meropenem
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Scand J Infect Dis 38:807-10. 2006
    ..The patient was cured only after the continuous intravenous administration of meropenem of 6 g/d...
  31. doi request reprint Pulmonary drug delivery systems for antimicrobial agents: facts and myths
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:101-6. 2010
    ..Cost is an important parameter, which may be counterbalanced in cystic fibrosis patients by a better quality of life and a greater adherence to treatment...
  32. ncbi request reprint Comparison of utility of blood cultures from intravascular catheters and peripheral veins: a systematic review and decision analysis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Med Microbiol 57:1-8. 2008
    ..Given the consequences of undertreating patients with bacteraemia, the authors believe that, based on the available evidence, at least one blood culture should be obtained from the intravascular catheter...
  33. doi request reprint Outcome of antimicrobial therapy in documented biofilm-associated infections: a review of the available clinical evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Drugs 69:1351-61. 2009
    ..Although some regimens might be more appropriate in this setting, further research on novel therapeutic strategies is needed to improve the outcome of patients with biofilm-associated infections...
  34. doi request reprint Effect of meteorological variables on the incidence of respiratory tract infections
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Respir Med 102:733-7. 2008
    ..The possible effect of the various meteorological variables on the incidence of upper and lower respiratory tract infections (RTIs) has intrigued the scientific community for decades...
  35. ncbi request reprint Matching criteria in case-control studies in the field of antimicrobial resistance
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Microb Drug Resist 14:171-82. 2008
    ..We evaluated the available evidence from case-control studies in the field of antimicrobial resistance to identify the degree that matching was performed and the criteria used to do so...
  36. ncbi request reprint Probiotics for the treatment of women with bacterial vaginosis
    M E Falagas
    Alfa Institute of Biomedical Sciences, Marousi, Greece
    Clin Microbiol Infect 13:657-64. 2007
    ..Thus, although the available results concerning the effectiveness of the administration of lactobacilli for the treatment of BV are mostly positive, it cannot yet be concluded definitively that probiotics are useful for this purpose...
  37. ncbi request reprint Risk factors for mortality in patients with emphysematous pyelonephritis: a meta-analysis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Urol 178:880-5; quiz 1129. 2007
    ..We identified the factors associated with mortality in patients with emphysematous pyelonephritis and estimated the magnitude of the associations...
  38. ncbi request reprint Obesity and infection
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Lancet Infect Dis 6:438-46. 2006
    ..Large prospective studies are required to further define the burden of infectious morbidity and mortality conferred by obesity...
  39. doi request reprint Urinary tract infections after pelvic floor gynecological surgery: prevalence and effect of antimicrobial prophylaxis. A systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, Marousi, 151 23 Athens, Greece
    Int Urogynecol J Pelvic Floor Dysfunct 19:1165-72. 2008
    ..6%), metronidazole plus ampicillin (20%), metronidazole (10-22.7%), or ciprofloxacin (27.2%). The use of a cephalosporin as perioperative antimicrobial prophylaxis is the optimal regimen in preventing UTIs after pelvic floor surgery...
  40. doi request reprint Meta-analysis: ertapenem for complicated intra-abdominal infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Aliment Pharmacol Ther 27:919-31. 2008
    ..Ertapenem is a new member of the carbapenem class of antibiotics, with a favourable pharmacokinetic profile, but a narrower spectrum of antimicrobial activity, compared with older representatives of this class...
  41. pmc Trends in the methodological quality of published randomized controlled trials on antibacterial agents
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Br J Clin Pharmacol 65:942-54. 2008
    ..g. nephrology, hepatology, oncology). However, there is lack of data regarding the trends in the methodological quality of RCTs focusing on antimicrobial agents...
  42. ncbi request reprint Informed consent: how much and what do patients understand?
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Am J Surg 198:420-35. 2009
    ..We sought to evaluate the degree of patients' understanding of several aspects of the informed consent process for surgery and clinical research...
  43. ncbi request reprint Benefit-risk assessment of linezolid for serious gram-positive bacterial infections
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Drug Saf 31:753-68. 2008
    ....
  44. ncbi request reprint Pyomyositis associated with hematological malignancy: case report and review of the literature
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Infect Dis 12:120-5. 2008
    ..8%) of the patients. Thirty out of 44 (68.2%) of the patients had a successful outcome. Death occurred in 5/44 (11.4%) patients. In cases of pyomyositis, the physician should consider an underlying hematological malignancy...
  45. ncbi request reprint Gangrenous, hemorrhagic, bullous cellulitis associated with pseudomonas aeruginosa in a patient with Waldenström's macroglobulinemia
    M E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, Marousi, 151 23, Athens, Greece
    Infection 35:370-3. 2007
    ..Patients with Waldenström's macroglobulinemia may manifest several types of skin lesions. We present our experience with a patient with the disease that adds to the literature on the topic...
  46. doi request reprint Potential of old-generation antibiotics to address current need for new antibiotics
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Marousi, Athens, Greece
    Expert Rev Anti Infect Ther 6:593-600. 2008
    ..The availability of novel genetic and molecular modification methods provides hope that the toxicity and efficacy drawbacks presented by some of these agents can be surpassed in the future...
  47. doi request reprint Intravenous colistimethate (colistin) use in critically ill children without cystic fibrosis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Pediatr Infect Dis J 28:123-7. 2009
    ..The increasing frequency of infections caused by multidrug-resistant (MDR) Gram-negative bacteria has led to the reappraisal of colistimethate use...
  48. ncbi request reprint Probiotic bacteria and biosurfactants for nosocomial infection control: a hypothesis
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Hosp Infect 71:301-6. 2009
    ..This could potentially impede a central step in the pathogenesis of nosocomial infections...
  49. pmc Percutaneous exposure incidents of the health care personnel in a newly founded tertiary hospital: a prospective study
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 2:e194. 2007
    ..We undertook this study in order to estimate the overall incidence of such injuries in a newly founded tertiary hospital, and to evaluate possible changes in their incidence over time...
  50. ncbi request reprint Fosfomycin for the treatment of multidrug-resistant, including extended-spectrum beta-lactamase producing, Enterobacteriaceae infections: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Lancet Infect Dis 10:43-50. 2010
    ..8%) of the 80 patients evaluated. Initial clinical data support the use of fosfomycin for the treatment of urinary tract infections caused by these pathogens, although further research is needed...
  51. ncbi request reprint Relative frequency of albicans and the various non-albicans Candida spp among candidemia isolates from inpatients in various parts of the world: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Infect Dis 14:e954-66. 2010
    ..Candidemia is among the leading causes of nosocomial bloodstream infections and is associated with significant mortality. Several centers have published data regarding the incidence and relative frequency of Candida spp...
  52. ncbi request reprint Ertapenem use and antimicrobial resistance to group 2 carbapenems in Gram-negative infections: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Expert Rev Anti Infect Ther 11:69-78. 2013
    ..In conclusion, the currently available data suggest that ertapenem use does not affect the resistance of Gram-negative bacteria to group 2 carbapenems...
  53. ncbi request reprint Patients included in randomised controlled trials do not represent those seen in clinical practice: focus on antimicrobial agents
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 36:1-13. 2010
    ..The application of the findings of RCTs to the care of individual patients should be performed cautiously...
  54. ncbi request reprint Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 32:450-4. 2008
    ..Antibiotics that are ineffective in vitro may prove life-saving for some of these patients, especially combination regimens containing colistin...
  55. ncbi request reprint Probiotics for prevention of recurrent vulvovaginal candidiasis: a review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS Athens, Greece
    J Antimicrob Chemother 58:266-72. 2006
    ..In conclusion, despite the promising results of some studies, further research is needed to prove the effectiveness of probiotics in preventing the recurrences of VVC and to allow their wide use for this indication...
  56. ncbi request reprint Re-emergence of colistin in today's world of multidrug-resistant organisms: personal perspectives
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Expert Opin Investig Drugs 17:973-81. 2008
    ..Infections due to multidrug-resistant Gram-negative bacteria (including Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae) are being reported with increasing frequency from various parts of the world...
  57. ncbi request reprint Infectious disease cases for educational purposes: open-access resources on the Internet
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 1st IKA Hospital, Athens, Greece
    Clin Infect Dis 45:495-500. 2007
    ....
  58. doi request reprint Clinical practice of obtaining blood cultures from patients with a central venous catheter in place: an international survey
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Department of Medicine, Henry Dunant Hospital, Athens, Greece
    Clin Microbiol Infect 15:683-6. 2009
    ..Clinicians who, according to the survey, demonstrated that they know the diagnostic performance characteristics of cultures more often obtain one culture from the CVC and one from the PV (73.9% vs. 61.7%, p 0.037)...
  59. ncbi request reprint The therapeutic effect of balneotherapy: evaluation of the evidence from randomised controlled trials
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Clin Pract 63:1068-84. 2009
    ..Systematic review...
  60. doi request reprint Antibiotics versus placebo in the treatment of women with uncomplicated cystitis: a meta-analysis of randomized controlled trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Infect 58:91-102. 2009
    ..However, emergence of resistant uropathogens forces physicians to reconsider the prescription of antibiotics for acute uncomplicated cystitis in non-pregnant young women...
  61. ncbi request reprint Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of tigecycline
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Curr Drug Metab 10:13-21. 2009
    ..However, gastrointestinal toxicity (nausea and vomiting) is usually dose-limiting. Further research is recommended on therapeutic strategies to optimize the effectiveness and safety of tigecycline therapy in severely ill patients...
  62. ncbi request reprint Antimicrobial resistance of Esherichia coli urinary isolates from primary care patients in Greece
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Med Sci Monit 14:CR75-79. 2008
    ..A retrospective analysis of microbiological data of the antimicrobial susceptibility of Escherichia coli urinary isolates from primary care patients in Greece was performed here...
  63. doi request reprint An analysis of trends in globalisation of origin of research published in major general medical journals
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Clin Pract 62:71-5. 2008
    ..There is an ongoing discussion in the scientific community that even the leading scientific journals publish mainly research that is produced in the countries where these journals are based...
  64. ncbi request reprint Oral rifampin for prevention of S. aureus carriage-related infections in patients with renal failure--a meta-analysis of randomized controlled trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Nephrol Dial Transplant 21:2536-42. 2006
    ..Rifampin has been studied as prophylaxis against Staphylococcus aureus-related infections in patients on dialysis...
  65. ncbi request reprint Administration of antibiotics via the respiratory tract as monotherapy for pneumonia
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Expert Rev Anti Infect Ther 6:447-52. 2008
    ..Clinicians are encouraged to publish any relevant experience in order for a considerable body of literature to be accumulated...
  66. pmc Impact of antibiotic MIC on infection outcome in patients with susceptible Gram-negative bacteria: a systematic review and meta-analysis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Antimicrob Agents Chemother 56:4214-22. 2012
    ..39; 95% CI, 1.19 to 4.81). The limited available data suggest that there is an association between high MICs, within the susceptible range, and adverse outcomes for patients with Gram-negative infections...
  67. ncbi request reprint At what age do biomedical scientists do their best work?
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos St, 151 23 Marousi, Athens, Greece
    FASEB J 22:4067-70. 2008
    ..In conclusion, high-quality scientific productivity in the biomedical fields as a function of investigator's age plots an inverted U-shaped curve, in which significant decreases take place from around 40 yr of age and beyond...
  68. doi request reprint Tigecycline for the treatment of multidrug-resistant Enterobacteriaceae: a systematic review of the evidence from microbiological and clinical studies
    Theodoros Kelesidis
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Antimicrob Chemother 62:895-904. 2008
    ....
  69. ncbi request reprint Old antibiotics for infections in critically ill patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Curr Opin Crit Care 13:592-7. 2007
    ..This review highlights the effectiveness and safety of older antibiotics when used in the treatment of infections of critically ill patients...
  70. ncbi request reprint Fosfomycin: use beyond urinary tract and gastrointestinal infections
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Clin Infect Dis 46:1069-77. 2008
    ....
  71. doi request reprint Epidemiological aspects of 2009 H1N1 influenza: the accumulating experience from the Northern Hemisphere
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, Marousi, 151 23, Athens, Greece
    Eur J Clin Microbiol Infect Dis 29:1327-47. 2010
    ..The evaluation of the currently available published evidence contributes to the clarification of the epidemiological features of pandemic 2009 A(H1N1) influenza, which is useful in terms of the individual and public health perspectives...
  72. ncbi request reprint Intraventricular or intrathecal use of polymyxins in patients with Gram-negative meningitis: a systematic review of the available evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 29:9-25. 2007
    ..Further studies are needed to evaluate the criteria for initiation of local central nervous system treatment with polymyxins, the optimal dosages and the role of adjuvant systemic or local therapy...
  73. ncbi request reprint Rifampicin-impregnated central venous catheters: a meta-analysis of randomized controlled trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 59:359-69. 2007
    ..The use of antimicrobial-impregnated central venous catheters (CVCs) for the prevention of CVC microbial colonization and catheter-related bloodstream infection (CRBSI) remains controversial...
  74. ncbi request reprint Local administration of polymyxins into the respiratory tract for the prevention and treatment of pulmonary infections in patients without cystic fibrosis
    M E Falagas
    Alfa Institute of Biomedical Sciences, Marousi, Greece
    Infection 35:3-10. 2007
    ..The available evidence supports that the local administration of polymyxins into the respiratory tract for the prevention and treatment of multidrug-resistant (MDR) Gram-negative bacterial infections deserves further investigation...
  75. ncbi request reprint Impact of initial discordant treatment with beta-lactam antibiotics on clinical outcomes in adults with pneumococcal pneumonia: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos St, 151 23 Marousi, Athens, Greece
    Mayo Clin Proc 81:1567-74. 2006
    ..To systematically examine the available evidence regarding the effect of initial discordant therapy with beta-lactam antibiotics on mortality, clinical success, and bacteriological eradication in patients with pneumococcal pneumonia...
  76. ncbi request reprint Infection-related morbidity and mortality in patients with connective tissue diseases: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Clin Rheumatol 26:663-70. 2007
    ..In addition, there are no data regarding the effect of prophylactic practices involving antibiotic administration in morbidity and mortality...
  77. ncbi request reprint Meta-analysis: randomized controlled trials of clindamycin/aminoglycoside vs. beta-lactam monotherapy for the treatment of intra-abdominal infections
    M E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Aliment Pharmacol Ther 25:537-56. 2007
    ..To compare the effectiveness and safety of clindamycin/aminoglycoside with broad-spectrum beta-lactam monotherapy in patients with intra-abdominal infections by performing a meta-analysis of randomized controlled trials (RCTs)...
  78. ncbi request reprint Science in Greece: from the age of Hippocrates to the age of the genome
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos St, Marousi 151 23, Greece
    FASEB J 20:1946-50. 2006
  79. doi request reprint Attributable mortality of Stenotrophomonas maltophilia infections: a systematic review of the literature
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Marousi, Athens, Greece
    Future Microbiol 4:1103-9. 2009
    ..We searched PubMed, Scopus and Cochrane and assessed the available literature regarding mortality attributable to infection with S. maltophilia...
  80. doi request reprint Treatment options for 2009 H1N1 influenza: evaluation of the published evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:421-30. 2010
    ..Studies with a comparative design, as well as randomised studies are needed to clarify further this issue of major importance...
  81. ncbi request reprint World Wide Web resources on antimicrobial resistance
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Clin Infect Dis 43:630-3. 2006
    ....
  82. ncbi request reprint Daptomycin for treatment of patients with bone and joint infections: a systematic review of the clinical evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 30:202-9. 2007
    ..Although these reports are encouraging, the relatively frequent emergence of antimicrobial resistance associated with prolonged administration of daptomycin should be considered seriously...
  83. doi request reprint Resistance to polymyxins: Mechanisms, frequency and treatment options
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Drug Resist Updat 13:132-8. 2010
    ..Polymyxin combination regimens, tigecycline and fosfomycin may be useful options for the treatment of polymyxin-resistant gram-negative infections...
  84. pmc Albendazole versus praziquantel in the treatment of neurocysticercosis: a meta-analysis of comparative trials
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS Negl Trop Dis 2:e194. 2008
    ..We investigated the role of albendazole and praziquantel in the treatment of patients with parenchymal neurocysticercosis by performing a meta-analysis of comparative trials of their effectiveness and safety...
  85. pmc Efficacy and safety of telavancin in clinical trials: a systematic review and meta-analysis
    Konstantinos A Polyzos
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 7:e41870. 2012
    ..aureus (MRSA). Telavancin is a bactericidal lipoglycopeptide with potent activity against Gram-positive pathogens...
  86. pmc Impact of vacuum-assisted closure (VAC) therapy on clinical outcomes of patients with sternal wound infections: a meta-analysis of non-randomized studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 8:e64741. 2013
    ..To examine the impact of VAC therapy on mortality of patients with sternal wound infections after cardiothoracic surgery...
  87. pmc Venetian rule and control of plague epidemics on the Ionian Islands during 17th and 18th centuries
    Katerina Konstantinidou
    Department of History and Archaeology, National and Kapodistrian University of Athens, Athens, Greece
    Emerg Infect Dis 15:39-43. 2009
    ..We conclude that even in the absence of scientific knowledge, close observation and social and political measures can effectively restrain infectious outbreaks to the point of disappearance...
  88. pmc The impact of article length on the number of future citations: a bibliometric analysis of general medicine journals
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Marousi, Athens, Greece
    PLoS ONE 8:e49476. 2013
    ..The number of citations received is considered an index of study quality and impact. We aimed to examine the factors associated with the number of citations of published articles, focusing on the article length...
  89. pmc Mapping health literacy research in the European Union: a bibliometric analysis
    Barbara K Kondilis
    Alfa Institute of Biomedical Sciences, Athens, Greece
    PLoS ONE 3:e2519. 2008
    ..To examine and compare the research productivity on selected fields related to health literacy of the current members of the European Union, the four candidate countries waiting to join the EU, Norway, Switzerland, and the United States...
  90. pmc continuous versus conventional infusion of amphotericin B deoxycholate: a meta-analysis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece Department of Internal Medicine Infectious Diseases, Mitera Hospital, Hygeia group, Athens, Greece Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, United States of America
    PLoS ONE 8:e77075. 2013
    ..We sought to study whether continuous infusion of AmB deoxycholate reduces nephrotoxicity retaining, however, the effectiveness of the drug...
  91. pmc MRSA in Africa: filling the global map of antimicrobial resistance
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 8:e68024. 2013
    ..The prevalence of MRSA was lower than 50% in most of the African countries, although it appears to have risen since 2000 in many African countries, except for South Africa. ..
  92. pmc Trends of mortality due to septicemia in Greece: an 8-year analysis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 8:e67621. 2013
    ..Infectious diseases are among the major causes of death worldwide. We evaluated the trends of mortality due to septicemia in Greece and compared it with mortality due to other infections...
  93. pmc Understanding of statistical terms routinely used in meta-analyses: an international survey among researchers
    Michael N Mavros
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 8:e47229. 2013
    ..Biomedical literature is increasingly enriched with literature reviews and meta-analyses. We sought to assess the understanding of statistical terms routinely used in such studies, among researchers...
  94. pmc Patients' perception of quality of pre-operative informed consent in athens, Greece: a pilot study
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    PLoS ONE 4:e8073. 2009
    ..We sought to perform a study to record and evaluate patients' views of the way surgeons communicate informed consent (IC) in Greece...
  95. pmc Temporal trends in the impact factor of European versus USA biomedical journals
    Drosos E Karageorgopoulos
    Alfa Institute of Biomedical Sciences, Athens, Greece
    PLoS ONE 6:e16300. 2011
    ....
  96. pmc Do psychological variables affect early surgical recovery?
    Michael N Mavros
    Alfa Institute of Biomedical Sciences, Athens, Greece
    PLoS ONE 6:e20306. 2011
    ..Numerous studies have examined the effect of psychological variables on surgical recovery, but no definite conclusion has been reached yet. We sought to examine whether psychological factors influence early surgical recovery...
  97. pmc Age distribution of cases of 2009 (H1N1) pandemic influenza in comparison with seasonal influenza
    Drosos E Karageorgopoulos
    Alfa Institute of Biomedical Sciences, Athens, Greece
    PLoS ONE 6:e21690. 2011
    ..Several aspects of the epidemiology of 2009 (H1N1) pandemic influenza have not been accurately determined. We sought to study whether the age distribution of cases differs in comparison with seasonal influenza...
  98. pmc Morbidity and outcomes of foreign travelers in zakynthos island, Greece: a retrospective study
    Eleni Plessa
    Zante Medical Care ZanteMed, Zakynthos, Greece Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS ONE 9:e94416. 2014
    ..We sought to evaluate the morbidity of foreign travelers in Zakynthos, a popular Greek island attracting large number of foreign tourists every summer...
  99. pmc World wide web resources on obstetrical and gynecological infections
    Stavros Athanasiou
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Infect Dis Obstet Gynecol 2007:29232. 2007
    ..We believe that the availability of such a list will help in the education of students and clinicians interested in obstetrical and gynecological infections...