Susan M Graham

Summary

Publications

  1. doi request reprint Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: a systematic review
    Susan M Graham
    Department of Medicine, University of Washington Seattle, WA, USA
    Virulence 4:564-71. 2013
  2. pmc Adherence to antiretroviral therapy and clinical outcomes among young adults reporting high-risk sexual behavior, including men who have sex with men, in coastal Kenya
    Susan M Graham
    Departments of Medicine and Global Health, University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    AIDS Behav 17:1255-65. 2013
  3. pmc Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:114-7. 2011
  4. pmc Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
    Susan M Graham
    University of Washington, Seattle, Washington 98104 2499, USA
    J Infect Dis 202:1538-42. 2010
  5. pmc A prospective study of vaginal trichomoniasis and HIV-1 shedding in women on antiretroviral therapy
    Linnet N Masese
    Department of Epidemiology, Box 357236, University of Washington, Seattle, Washington 98195, USA
    BMC Infect Dis 11:307. 2011
  6. pmc Association between participant self-report and biological outcomes used to measure sexual risk behavior in human immunodeficiency virus-1-seropositive female sex workers in Mombasa, Kenya
    R Scott McClelland
    Departments of Medicine, University of Washington, Seattle, WA, USA
    Sex Transm Dis 38:429-33. 2011
  7. ncbi request reprint A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 23:1197-200. 2007
  8. pmc Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
    Susan M Graham
    Departments of Medicine, Epidemiology and Global Health, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 52:600-3. 2009
  9. pmc Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104 2499, USA
    AIDS 27:1803-13. 2013
  10. pmc Loss to follow-up as a competing risk in an observational study of HIV-1 incidence
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 8:e59480. 2013

Collaborators

Detail Information

Publications24

  1. doi request reprint Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: a systematic review
    Susan M Graham
    Department of Medicine, University of Washington Seattle, WA, USA
    Virulence 4:564-71. 2013
    ..Our objective was to review the evidence regarding the clinical utility of endothelial activation and coagulation biomarkers for the prognosis of HIV-infected patients...
  2. pmc Adherence to antiretroviral therapy and clinical outcomes among young adults reporting high-risk sexual behavior, including men who have sex with men, in coastal Kenya
    Susan M Graham
    Departments of Medicine and Global Health, University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    AIDS Behav 17:1255-65. 2013
    ..5 kg/year), CD4 counts did not differ. More data are needed on barriers to adherence and clinical outcomes among African MSM, to ensure that MSM can access care and derive treatment and prevention benefits from ART...
  3. pmc Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:114-7. 2011
    ..The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective of this study was to test the hypothesis that genital ulcerations increase genital HIV-1-RNA shedding in women receiving ART...
  4. pmc Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
    Susan M Graham
    University of Washington, Seattle, Washington 98104 2499, USA
    J Infect Dis 202:1538-42. 2010
    ..04). These results emphasize the importance of adherence to optimize the potential benefits of ART for reducing HIV-1 transmission risk...
  5. pmc A prospective study of vaginal trichomoniasis and HIV-1 shedding in women on antiretroviral therapy
    Linnet N Masese
    Department of Epidemiology, Box 357236, University of Washington, Seattle, Washington 98195, USA
    BMC Infect Dis 11:307. 2011
    ..We tested the hypothesis that T. vaginalis infection would increase vaginal HIV-1 RNA shedding in women on ART, and that successful treatment would reduce vaginal HIV-1 RNA levels...
  6. pmc Association between participant self-report and biological outcomes used to measure sexual risk behavior in human immunodeficiency virus-1-seropositive female sex workers in Mombasa, Kenya
    R Scott McClelland
    Departments of Medicine, University of Washington, Seattle, WA, USA
    Sex Transm Dis 38:429-33. 2011
    ..Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults...
  7. ncbi request reprint A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 23:1197-200. 2007
    ..0, p = 0.008). Trends for an increased risk of mortality were also seen. A greater decrease in albumin levels accompanying HIV-1 acquisition may be a marker for changes in early infection associated with more rapid disease progression...
  8. pmc Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
    Susan M Graham
    Departments of Medicine, Epidemiology and Global Health, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 52:600-3. 2009
    ..To better define this risk, we monitored 134 women at ART initiation and monthly thereafter...
  9. pmc Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104 2499, USA
    AIDS 27:1803-13. 2013
    ..We aimed to determine whether endothelial activation biomarkers increase after HIV-1 acquisition, and whether biomarker levels measured in chronic infection would predict disease progression and death in HIV-1 seroconverters...
  10. pmc Loss to follow-up as a competing risk in an observational study of HIV-1 incidence
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 8:e59480. 2013
    ..Our goal was to assess whether the association between sexual risk behavior and HIV-1 acquisition changed after accounting for LTF with competing risks regression...
  11. pmc HIV-1 RNA may decline more slowly in semen than in blood following initiation of efavirenz-based antiretroviral therapy
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 7:e43086. 2012
    ..Our objective was to study the time course and magnitude of seminal HIV-1 RNA decay after initiation of efavirenz-based ART among 13 antiretroviral-naïve Kenyan men...
  12. pmc Prospective study of vaginal bacterial flora and other risk factors for vulvovaginal candidiasis
    R Scott McClelland
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    J Infect Dis 199:1883-90. 2009
    ..Our objective was to determine the relationship between vaginal bacterial flora and VVC...
  13. pmc Prevalence, clinical and virologic outcomes of hepatitis B virus co-infection in HIV-1 positive Kenyan women on antiretroviral therapy
    Summer L Day
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 8:e59346. 2013
    ..We aimed to determine the prevalence, clinical, and virologic outcomes of chronic HBV infection, including HBV resistance to lamivudine, in a cohort of HIV-1 seropositive Kenyan women on long-term ART...
  14. pmc Antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, WA 98104 2499, USA
    J Acquir Immune Defic Syndr 60:511-8. 2012
    ..Our objective was to identify predictors of drug-resistant HIV-1 RNA in genital secretions after initiation of nonnucleoside reverse transcriptase inhibitor-based therapy...
  15. pmc A prospective study of risk factors for bacterial vaginosis in HIV-1-seronegative African women
    R Scott McClelland
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    Sex Transm Dis 35:617-23. 2008
    ..Bacterial vaginosis (BV) is common and has been associated with increased HIV-1 susceptibility. The objective of this study was to identify risk factors for BV in African women at high risk for acquiring HIV-1...
  16. ncbi request reprint A Prospective Cohort Study of the Effect of Depot Medroxyprogesterone Acetate on Detection of Plasma and Cervical HIV-1 in Women Initiating and Continuing Antiretroviral Therapy
    Summer Day
    Department of Medicine, University of Washington, Seattle, WA Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya Departments of Epidemiology Biostatistics Global Health, University of Washington, Seattle WA Fred Hutchinson Cancer Research Center, Seattle, WA Department of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya and Pathcare Laboratories, Mombasa, Kenya
    J Acquir Immune Defic Syndr 66:452-6. 2014
    ..39) or cervical HIV-1 RNA (adjusted odds ratio: 1.41, 95% confidence interval: 0.54 to 3.67). Our results suggest that DMPA is unlikely to increase infectivity in HIV-positive women who are adherent to effective antiretroviral therapy. ..
  17. pmc Evaluation of an empiric risk screening score to identify acute and early HIV-1 infection among MSM in Coastal Kenya
    Elizabeth Wahome
    aCentre for Geographic Medicine Research Coast, Kenya Medical Research Institute Kilifi, Kilifi, Kenya bNuffield Department of Clinical Medicine, University of Oxford, Headington, UK cInternational AIDS Vaccine Initiative, New York dUniversity of Washington, Seattle, Washington, USA
    AIDS 27:2163-6. 2013
    ..85. Screening for AEHI will have substantial transmission prevention benefits. ..
  18. pmc Treatment with antiretroviral therapy is not associated with increased sexual risk behavior in Kenyan female sex workers
    R Scott McClelland
    Department of Medicine, University of Washington, Seattle, USA
    AIDS 24:891-7. 2010
    ..The objective of this study was to test the hypothesis that sexual risk behavior would increase following initiation of antiretroviral therapy (ART) in Kenyan female sex workers (FSWs)...
  19. pmc Prevalence and correlates of genital warts in Kenyan female sex workers
    Barbara E Kavanaugh
    University of Washington, Seattle, WA, USA
    Sex Transm Dis 39:902-5. 2012
    ..Because of the high prevalence of human immunodeficiency virus type 1 (HIV-1) in this population, we were particularly interested in the association between HIV-1 infection and genital warts...
  20. pmc A decrease in albumin in early SIV infection is related to viral pathogenicity
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98104, USA
    AIDS Res Hum Retroviruses 25:433-40. 2009
    ..These results suggest that both early and late events in SIV pathogenesis are influenced by properties of the infecting viral strain...
  21. pmc Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:232-7. 2011
    ..Because semen collection is often impractical, the acceptability, feasibility and validity of post-prostatic massage fluid/urine (post-PMF/U) was evaluated for studying male genitourinary HIV-1 shedding...
  22. pmc A systematic review of the quality of trials evaluating biomedical HIV prevention interventions shows that many lack power
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, USA
    HIV Clin Trials 10:413-31. 2009
    ..We aimed to identify, describe, and evaluate the quality of RCTs studying biomedical interventions to prevent HIV acquisition by sexual transmission...
  23. pmc Higher pre-infection vitamin E levels are associated with higher mortality in HIV-1-infected Kenyan women: a prospective study
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    BMC Infect Dis 7:63. 2007
    ..However, vitamin E supplementation has also been reported to increase CCR5 expression, which could increase HIV-1 replication. We hypothesized that vitamin E levels at HIV-1 acquisition may influence disease progression...