Eduardo Gotuzzo

Summary

Publications

  1. pmc Efficacy and duration of immunity after yellow fever vaccination: systematic review on the need for a booster every 10 years
    Eduardo Gotuzzo
    Instituto de Medicina Tropical Alexander von Humbolt, Lima, Peru
    Am J Trop Med Hyg 89:434-44. 2013
  2. ncbi request reprint [Researchers training in the context of the collaborative projects: experiences of Instituto de Medicina Tropical "Alexander von Humbolt", Universidad Peruana Cayetano Heredia]
    Eduardo Gotuzzo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Peru Med Exp Salud Publica 27:419-27. 2010
  3. doi request reprint Evaluation of host genetic and viral factors as surrogate markers for HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian HTLV-1-infected patients
    Michael Talledo
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Med Virol 82:460-6. 2010
  4. ncbi request reprint Frequent HTLV-1 infection in the offspring of Peruvian women with HTLV-1-associated myelopathy/tropical spastic paraparesis or strongyloidiasis
    Eduardo Gotuzzo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Avenida Honorio Delgado 430, Lima, Peru
    Rev Panam Salud Publica 22:223-30. 2007
  5. doi request reprint Possible implication of NFKB1A and NKG2D genes in susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian patients infected with HTLV-1
    Michael Talledo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Med Virol 84:319-26. 2012
  6. pmc IFN-gamma production in response to Tax 161-233, and frequency of CD4+ Foxp3+ and Lin HLA-DRhigh CD123+ cells, discriminate HAM/TSP patients from asymptomatic HTLV-1-carriers in a Peruvian population
    Ivan Best
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Immunology 128:e777-86. 2009
  7. doi request reprint Comparison of three ELISAs for the routine diagnosis of human T-lymphotropic virus infection in a high-prevalence setting in Peru
    Kristien Verdonck
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430, Lima 31, Peru
    Trans R Soc Trop Med Hyg 103:420-2. 2009
  8. pmc Venezuelan equine encephalitis and 2 human deaths, Peru
    Stalin Vilcarromero
    Naval Medical Research Center Detachment, Lima, Peru
    Emerg Infect Dis 16:553-6. 2010
  9. doi request reprint Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru
    Michael Talledo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Hum Immunol 71:804-8. 2010
  10. pmc A diagnostic accuracy study of Xpert®MTB/RIF in HIV-positive patients with high clinical suspicion of pulmonary tuberculosis in Lima, Peru
    Gabriela Carriquiry
    Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS ONE 7:e44626. 2012

Detail Information

Publications63

  1. pmc Efficacy and duration of immunity after yellow fever vaccination: systematic review on the need for a booster every 10 years
    Eduardo Gotuzzo
    Instituto de Medicina Tropical Alexander von Humbolt, Lima, Peru
    Am J Trop Med Hyg 89:434-44. 2013
    ..Therefore, a booster dose of YF vaccine is not needed. Special considerations for selected populations are detailed. ..
  2. ncbi request reprint [Researchers training in the context of the collaborative projects: experiences of Instituto de Medicina Tropical "Alexander von Humbolt", Universidad Peruana Cayetano Heredia]
    Eduardo Gotuzzo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Peru Med Exp Salud Publica 27:419-27. 2010
    ....
  3. doi request reprint Evaluation of host genetic and viral factors as surrogate markers for HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian HTLV-1-infected patients
    Michael Talledo
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Med Virol 82:460-6. 2010
    ..A logistic model containing PVL, age, gender, and HLA-A*02 provided the best predictive ability in the Peruvian cohort (AUC = 0.79). J. Med. Virol. 82:460-466, 2010. (c) 2010 Wiley-Liss, Inc...
  4. ncbi request reprint Frequent HTLV-1 infection in the offspring of Peruvian women with HTLV-1-associated myelopathy/tropical spastic paraparesis or strongyloidiasis
    Eduardo Gotuzzo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Avenida Honorio Delgado 430, Lima, Peru
    Rev Panam Salud Publica 22:223-30. 2007
    ....
  5. doi request reprint Possible implication of NFKB1A and NKG2D genes in susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian patients infected with HTLV-1
    Michael Talledo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Med Virol 84:319-26. 2012
    ..Further replication studies in independent HTLV-1 patient groups should validate further these associations...
  6. pmc IFN-gamma production in response to Tax 161-233, and frequency of CD4+ Foxp3+ and Lin HLA-DRhigh CD123+ cells, discriminate HAM/TSP patients from asymptomatic HTLV-1-carriers in a Peruvian population
    Ivan Best
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Immunology 128:e777-86. 2009
    ....
  7. doi request reprint Comparison of three ELISAs for the routine diagnosis of human T-lymphotropic virus infection in a high-prevalence setting in Peru
    Kristien Verdonck
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430, Lima 31, Peru
    Trans R Soc Trop Med Hyg 103:420-2. 2009
    ..Six samples had discordant ELISA; Murex gave one false-negative result, Ortho two and Platelia one. In high-prevalence settings, it is recommended to test samples with two ELISAs before considering them HTLV-seronegative...
  8. pmc Venezuelan equine encephalitis and 2 human deaths, Peru
    Stalin Vilcarromero
    Naval Medical Research Center Detachment, Lima, Peru
    Emerg Infect Dis 16:553-6. 2010
    ..Deaths of 2 persons with evidence of acute VEE virus infection indicate that fatal VEEV infection in Peru is likely. Cases may remain underreported...
  9. doi request reprint Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru
    Michael Talledo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Hum Immunol 71:804-8. 2010
    ..Our study did not reveal significant associations between KIR genes and HLA-Cw groups and HAM/TSP or PVL. However, because our study was powered to detect only larger effects, additional studies using larger cohorts are needed...
  10. pmc A diagnostic accuracy study of Xpert®MTB/RIF in HIV-positive patients with high clinical suspicion of pulmonary tuberculosis in Lima, Peru
    Gabriela Carriquiry
    Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS ONE 7:e44626. 2012
    ..The majority of performance studies of MTB/RIF have been performed in high HIV burden settings, thus TB diagnostic studies among HIV patients in low HIV prevalence settings such as Peru are still needed...
  11. doi request reprint Short communication an interferon-γ ELISPOT assay with two cytotoxic T cell epitopes derived from HTLV-1 tax region 161-233 discriminates HTLV-1-associated myelopathy/tropical spastic paraparesis patients from asymptomatic HTLV-1 carriers in a Peruvian po
    Ivan Best
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    AIDS Res Hum Retroviruses 27:1207-12. 2011
    ..The HLA-A*6801 allele, which is predicted to bind to the Tax 181-193 peptide, was overpresented in the HAM/TSP patients tested...
  12. pmc Asymptomatic renal colonization of humans in the peruvian Amazon by Leptospira
    Christian A Ganoza
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS Negl Trop Dis 4:e612. 2010
    ..We hypothesized that, like mammalian reservoir hosts, humans develop asymptomatic leptospiruria in settings of high disease transmission such as the Peruvian Amazon...
  13. doi request reprint Diagnosis of soil-transmitted helminthiasis in an Amazonic community of Peru using multiple diagnostic techniques
    Jorge D Machicado
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Trans R Soc Trop Med Hyg 106:333-9. 2012
    ..intestinalis, H. nana, S. stercoralis and hookworm. In conclusion, the SSTT is not inferior to Kato-Katz for the diagnosis of common STH infections but is largely superior for detecting intestinal protozoa and S. stercoralis larvae...
  14. ncbi request reprint Predictors of CD4+ cell count response and of adverse outcome among HIV-infected patients receiving highly active antiretroviral therapy in a public hospital in Peru
    Diego López de Castilla
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Infect Dis 12:325-31. 2008
    ..Our aim was to investigate CD4+ cell recovery and adverse outcome after highly active antiretroviral therapy (HAART) under the Peruvian National Program for HIV...
  15. ncbi request reprint Sexual behavior, knowledge of STI prevention, and prevalence of serum markers for STI among tour guides in Cuzco/Peru
    Miguel M Cabada
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Travel Med 14:151-7. 2007
    ..The purpose of this study was to explore the sexual behavior, knowledge of STI prevention, and prevalence of serum markers of selected STIs in tour guides in Cuzco/Peru...
  16. pmc Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen
    Martin Montes
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS Negl Trop Dis 3:e456. 2009
    ..We hypothesize that HTLV-1 leads to dissemination of Strongyloides stercoralis infection by augmenting regulatory T cell numbers, which in turn down regulate the immune response to the parasite...
  17. doi request reprint CD4+ T cell subsets and Tax expression in HTLV-1 associated diseases
    Nicolas Barros
    Instituto de Medicina Tropical, Alexander von Humboldt, Universidad Peruana, Cayetano Heredia in Lima, Lima, Peru
    Pathog Glob Health 107:202-6. 2013
    ..We observed increased ratios of Th1/Treg among Tax expressing lymphocytes in HAM patients. These data suggest that the expression of Tax among the different target cells may explain the variable presentation of HTLV-1. ..
  18. pmc High prevalence of primary multidrug resistant tuberculosis in persons with no known risk factors
    Larissa Otero
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS ONE 6:e26276. 2011
    ..However, this approach might miss a substantial proportion of MDR-TB in the general population. We studied primary MDR in patients considered to be at low risk of MDR-TB in Lima, Peru...
  19. ncbi request reprint Development of a clinical scoring system for the diagnosis of smear-negative pulmonary tuberculosis
    Alonso Soto
    Hipólito Unanue National Hospital, Lima, Peru
    Braz J Infect Dis 12:128-32. 2008
    ..The score developed is a cheap and useful clinical tool for the diagnosis of SNPT and can be used to help therapeutic decisions in patients with suspicion of having SNPT...
  20. doi request reprint Self-reported health problems among travelers visiting Cuzco: a Peruvian Airport survey
    Miguel M Cabada
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430, San Martin de Porres, Lima, Peru
    Travel Med Infect Dis 7:25-9. 2009
    ..5%), and only 22.1% sought medical attention. It is concluded that a significant burden of disease is observed in travelers to Cuzco. Self-medication is very common and apparently preferred over formal medical attention...
  21. ncbi request reprint Human T-lymphotropic virus 1: recent knowledge about an ancient infection
    Kristien Verdonck
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Lancet Infect Dis 7:266-81. 2007
    ..The understanding of the interaction between virus and host response has improved markedly, but there are still no clear surrogate markers for prognosis and there are few treatment options...
  22. ncbi request reprint Evaluation of Fas2-ELISA for the serological detection of Fasciola hepatica infection in humans
    Jose R Espinoza
    Unit of Molecular Biotechnology, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 76:977-82. 2007
    ..Results show that Fas2-ELISA is a highly sensitive immunodiagnostic test for the detection of F. hepatica infection in children living in human fascioliasis endemic areas...
  23. doi request reprint Association between onychodystrophy and human T-lymphotropic virus type 1 infection
    Erick F Mayer
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Infect Dis 17:e312-6. 2013
    ..To assess the association between human T-lymphotropic virus type 1 (HTLV-1) infection and onychodystrophy...
  24. doi request reprint Pre-travel preparation for Cusco, Peru: a comparison between European and North American travelers
    Miguel M Cabada
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Travel Med 17:382-6. 2010
    ..Demographics, preferences on health care, and regional differences in pre-travel advice guidelines may influence the preparation of travelers to developing countries...
  25. doi request reprint Evaluation of the performance of two liquid-phase culture media for the diagnosis of pulmonary tuberculosis in a national hospital in Lima, Peru
    Alonso Soto
    Hospital Nacional Hipólito Unanue, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Infect Dis 13:40-5. 2009
    ..To evaluate the diagnostic performance of two liquid-phase culture media for the diagnosis of pulmonary tuberculosis...
  26. ncbi request reprint Epidemiology of Clostridium difficile-associated diarrhea in a Peruvian tertiary care hospital
    Coralith Garcia
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 77:802-5. 2007
    ..97; 95% CI, 1.14-7.76; P = 0.026) were significantly associated with CDAD. Hospital transmission of C. difficile commonly occurred, supporting infection-appropriate measures directed toward the reduction of CDAD in low-resource settings...
  27. ncbi request reprint Classic Kaposi's sarcoma presenting in the oral cavity of two HIV-negative Quechua patients
    Salim Mohanna
    HHV 8 and Classic Kaposi s Sarcoma Working Group, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Med Oral Patol Oral Cir Bucal 12:E365-8. 2007
    ..The awareness of oral classic KS as a diagnostic possibility is important in the work-up of vascular lesions in the oral cavity of non-immunosuppressed individuals...
  28. doi request reprint [Parasite intestinal infection and factors associated with coccidian infection in adults at public hospital in Lima, Peru]
    Omayra Chincha
    Instituto de Medicina Trópica Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Chilena Infectol 26:440-4. 2009
    ..To evaluate the frequency of intestinal parasites and risk factors associated with coccidian infection in patients cared for at a public hospital in Lima-Peru...
  29. doi request reprint Performance of an algorithm based on WHO recommendations for the diagnosis of smear-negative pulmonary tuberculosis in patients without HIV infection
    Alonso Soto
    Hospital Nacional Hipólito Unanue, Santiago de Surco, Lima, Peru
    Trop Med Int Health 16:424-30. 2011
    ..To evaluate the performance of an algorithm based on WHO recommendations for diagnosis of smear-negative pulmonary tuberculosis in HIV-negative patients...
  30. doi request reprint Human T-lymphotropic virus type 1 infection is frequent in rural communities of the southern Andes of Peru
    Fanny Ita
    Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru Electronic address
    Int J Infect Dis 19:46-52. 2014
    ..To evaluate the presence of human T-lymphotropic virus type 1 (HTLV-1) infection in isolated rural communities in the southern Andes of Peru...
  31. pmc A foodborne outbreak of brucellosis at a police station cafeteria, Lima, Peru
    Karina Román
    Department of Molecular and Cellular Sciences, Faculty of Sciences, and Laboratory of Research and Development, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 88:552-8. 2013
    ..These results provide rationale for public health investigations of brucellosis index cases including the bioterrorism-related dissemination of Brucella...
  32. doi request reprint Additional evidence to support the phasing-out of treatment category II regimen for pulmonary tuberculosis in Peru
    Mario Ponce
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Trans R Soc Trop Med Hyg 106:508-10. 2012
    ..8% (95% CI: 58.9-75.6.) vs 77.8% (95% CI: 75.3-80.2), p=0.014. Multi-drug resistance exerted a profound effect on cure rates in both regimens. Our results support the phasing-out of treatment category II regimen in Peru...
  33. doi request reprint Highly effective and inexpensive parasitological technique for diagnosis of intestinal parasites in developing countries: spontaneous sedimentation technique in tube
    Raúl Tello
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, San Martin de Porras, Lima, Peru
    Int J Infect Dis 16:e414-6. 2012
    ..The advantages of the SSTT are its ability to detect the majority of intestinal parasites, including eggs, larvae, cysts, and trophozoites, and its low cost...
  34. ncbi request reprint Use of ivermectin to treat an institutional outbreak of scabies in a low-resource setting
    Coralith Garcia
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Infect Control Hosp Epidemiol 28:1337-8. 2007
    ..Of these 23, a total of 5 healthcare workers had scabies confirmed by microscopy. Oral ivermectin was used to control the outbreak effectively...
  35. pmc Normalization of FoxP3(+) regulatory T cells in response to effective antiretroviral therapy
    Martin Montes
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Infect Dis 203:496-9. 2011
    ..1% at 48 weeks, similar to values in normal subjects. These data suggest that with effective therapy, the regulatory cell numbers normalize, and that the inflammatory signals driving their production may also abate...
  36. ncbi request reprint Natural history, clinicoradiologic correlates, and response to triclabendazole in acute massive fascioliasis
    Luis A Marcos
    Institute of Tropical Medicine Alexander von Humboldt IMTAvH, Universidad Peruana Cayetano Heredia UPCH, Lima, Peru
    Am J Trop Med Hyg 78:222-7. 2008
    ..Fascioliasis is specifically treatable with a single dose of triclabendazole...
  37. ncbi request reprint [Clostridium difficile and cytomegalovirus involved in a case of pseudomembranous colitis]
    Coralith Garcia
    Instituto de Medicina Tropical Alexander con Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Gastroenterol Peru 27:408-10. 2007
    ..We report an unusual case of pseudomembranous colitis with fatal outcome where C. difficile and cytomegalovirus coexistense in a Peruvian patient with AIDS and gastrointestinal compromise by a mycobacterium...
  38. ncbi request reprint [Hyperendemic and mesoendemic zones of Fasciola infection surrounding urban Lima : an emerging disease?]
    Luis Marcos
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Gastroenterol Peru 27:31-6. 2007
    ..The infection caused by F. hepatica is endemic in Perú with an increasing number of endemic areas, the reporting of them is essential to know the impact of the infection in the population...
  39. pmc Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis
    Cesar A Ugarte-Gil
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS ONE 8:e61333. 2013
    ..There are no data on the relationship between local tissue MMPs concentrations, anti-tuberculosis therapy and sputum conversion...
  40. pmc Staphylococcus aureus causing tropical pyomyositis, Amazon Basin, Peru
    Coralith Garcia
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Emerg Infect Dis 19:123-5. 2013
    ..Our findings suggest sequence type 25 is circulating in tropical areas of South America...
  41. pmc Clinical prediction rule for stratifying risk of pulmonary multidrug-resistant tuberculosis
    Dalila Martínez
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    PLoS ONE 5:e12082. 2010
    ..Multidrug-resistant tuberculosis (MDR-TB), resistance to at least isoniazid and rifampin, is a worldwide problem...
  42. pmc Evidence-based medicine training in a resource-poor country, the importance of leveraging personal and institutional relationships
    Cristina Tomatis
    Universidad Peruana Cayetano Heredia, Lima, Peru
    J Eval Clin Pract 17:644-50. 2011
    ..We describe the results of an international effort to improve research capacity in a developing country; we conducted a course aimed at improving basic EBM attitudes and identified challenges...
  43. doi request reprint Strongyloides stercoralis infection complicating the central nervous system
    Fernando Woll
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Handb Clin Neurol 114:229-34. 2013
    ..Treatment with a single dose of ivermectin is recommended for most patients. In severe or hyperinfection cases repeated doses may be needed. ..
  44. doi request reprint Intestinal protozoan infections in the immunocompromised host
    Luis A Marcos
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Curr Opin Infect Dis 26:295-301. 2013
    ..However, pathogenesis of infection is still poorly understood, diagnostic tests remain insensitive, and management continues to pose a challenge...
  45. ncbi request reprint Sustained efficacy and safety of raltegravir after 5 years of combination antiretroviral therapy as initial treatment of HIV-1 infection: final results of a randomized, controlled, phase II study (Protocol 004)
    Eduardo Gotuzzo
    Department to de Enfermedades Infecciosas y Tropicales, Hospital Nacional Cayetano Heredia, Lima, Peru
    J Acquir Immune Defic Syndr 61:73-7. 2012
    ..Few drug-related adverse events were reported after week 48. Raltegravir had minimal effect on laboratory values, including lipids. Raltegravir with tenofovir/lamivudine showed durable efficacy and good tolerability over 5 years...
  46. pmc Correlation of serotype-specific dengue virus infection with clinical manifestations
    Eric S Halsey
    United States Naval Medical Research Unit Six, Lima, Peru
    PLoS Negl Trop Dis 6:e1638. 2012
    ..The goal of this study was to estimate and compare the prevalence of non-hemorrhagic clinical manifestations of DENV infection by serotype...
  47. pmc Knowledge, attitudes and practice survey about antimicrobial resistance and prescribing among physicians in a hospital setting in Lima, Peru
    Coralith Garcia
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Clin Pharmacol 11:18. 2011
    ..The present study evaluated knowledge, attitudes and practices about AMR and AM prescribing among medical doctors in two large public hospitals in Lima, Peru, a middle-income country...
  48. ncbi request reprint SYBR Green-based quantitation of human T-lymphotropic virus type 1 proviral load in Peruvian patients with neurological disease and asymptomatic carriers: influence of clinical status, sex, and familial relatedness
    Vanessa Adaui
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Neurovirol 12:456-65. 2006
    ....
  49. ncbi request reprint Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement
    Dalila Y Martínez
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Clin Infect Dis 51:e7-11. 2010
    ..We describe a young, female patient who presented with extensive cutaneous and neurological involvement and who recovered after receiving prolonged treatment with miltefosine, fluconazole, and albendazole...
  50. ncbi request reprint Update on hepatobiliary flukes: fascioliasis, opisthorchiasis and clonorchiasis
    Luis A Marcos
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Curr Opin Infect Dis 21:523-30. 2008
    ..The present review focuses on current knowledge of clinical, diagnostic and treatment aspects caused by hepatobiliary flukes that can be applied to current protocols in endemic areas...
  51. pmc Histopathological features of tungiasis in Peru
    Vicente Maco
    Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY, USA
    Am J Trop Med Hyg 88:1212-6. 2013
    ..The Fortaleza staging may represent a tool for pathology reporting purposes...
  52. ncbi request reprint Oral rehydration solution to prevent nephrotoxicity of amphotericin B
    Juan Echevarria
    Departamento de Enfermedades Infecciosas, Tropicales y Dermatológicas Hospital Nacional Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 75:1108-12. 2006
    ..02). We conclude that ORS is comparable to SS in preventing glomerular damage of AB, but more effective in preventing hypokalemia...
  53. doi request reprint Brucellar uveitis: intraocular fluids and biopsy studies
    Isaias Rolando
    Hospital Nacional Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430, Lima 31, Peru
    Int J Infect Dis 13:e206-11. 2009
    ..Little is known with regard to the ocular immunology of brucellosis and the use of intraocular diagnostic tests. We report retrospectively the laboratory findings of patients with ocular involvement associated with brucellosis...
  54. pmc Research training needs in Peruvian national TB/HIV programs
    Patricia J Garcia
    Epidemiology, STI and HIV Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Med Educ 10:63. 2010
    ....
  55. pmc Venezuelan equine encephalitis and upper gastrointestinal bleeding in child
    Stalin Vilcarromero
    Naval Medical Research Center Detachment, Lima, Peru
    Emerg Infect Dis 15:323-5. 2009
    ..In 2006, VEE virus subtype ID was isolated from a boy with severe febrile disease and gastrointestinal bleeding; the strain contained 2 mutations within the PE2 region...
  56. doi request reprint Balamuthia mandrillaris infection of the skin and central nervous system: an emerging disease of concern to many specialties in medicine
    Francisco G Bravo
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Peru
    Curr Opin Infect Dis 24:112-7. 2011
    ..The ability of the clinician in recognizing the skin lesion early in the course of the disease may lead to a successful therapeutic intervention in an otherwise fatal disease...
  57. pmc High prevalence of HIV and syphilis in a remote native community of the Peruvian Amazon
    Carol Zavaleta
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 76:703-5. 2007
    ..The outcomes of this study highlight the need for urgent medical and anthropologic approaches to stop HIV transmission in indigenous Amazonian communities...
  58. ncbi request reprint Human herpesvirus-8 in Peruvian blood donors: a population with hyperendemic disease?
    Salim Mohanna
    Human Herpesvirus 8 and Classic Kaposi Sarcoma Working Group, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Clin Infect Dis 44:558-61. 2007
    ..An overall seroprevalence of 56.25% was found (male donors, 54.68%; female donors, 57.11%). These findings indicate that human herpesvirus-8 infection is hyperendemic in Peruvian blood donors...
  59. ncbi request reprint Outbreak of persistent cutaneous abscesses due to Mycobacterium chelonae after mesotherapy sessions, Lima, Peru
    Cesar V Munayco
    Direccion General de Epidemiologia, Ministerio de Salud, Lima, Peru
    Rev Saude Publica 42:146-9. 2008
    ..Mycobacterium chelonae was isolated from four patients and from a procaine vial. In conclusion, it is important to consider mesotherapy as a potential source of rapidly growing mycobacteria infections...
  60. ncbi request reprint Risk factors associated with diarrhea among international visitors to Cuzco, Peru
    Miguel M Cabada
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 75:968-72. 2006
    ..04). Remaining in Cuzco < 1 week was a protective factor (OR: 0.58). TD is common among travelers to Cuzco. This study suggests that conventional recommendations are not invariably effective at decreasing TD...
  61. pmc An ectopic case of Tunga spp. infection in Peru
    Vicente Maco
    Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 82:1076-8. 2010
    ..This is the first documented case of knee tungiasis in an endemic country. The historical, clinical, histological, and current epidemiological aspects of tungiasis in Peru are discussed here...
  62. doi request reprint Cost-effectiveness analysis of introduction of rapid, alternative methods to identify multidrug-resistant tuberculosis in middle-income countries
    Carlos Acuna-Villaorduna
    Instituto de Medicina Tropical Alexander von Humboldt, Lima, Peru
    Clin Infect Dis 47:487-95. 2008
    ..Conventional drug-susceptibility testing (DST) methods are slow and demanding. Alternative, rapid DST methods would permit the early detection of drug resistance and, in turn, arrest tuberculosis transmission...
  63. ncbi request reprint [Factors associated with strongyloides stercoralis infection in an endemic area in Peru]
    Julio Herrera
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Gastroenterol Peru 26:357-62. 2006
    ....