Roberta A Gottlieb

Summary

Publications

  1. pmc Cardioprotection through autophagy: ready for clinical trial?
    Roberta A Gottlieb
    Radical Therapeutix, Inc, Solana Beach, CA, USA
    Autophagy 7:434-5. 2011
  2. doi Measuring cardiac autophagic flux in vitro and in vivo
    Michael A Gurney
    Donald P Shiley BioScience Center, San Diego State University, 5500 Campanile Dr, San Diego, CA, 92182 4650, USA
    Methods Mol Biol 1219:187-97. 2015
  3. pmc Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
    Raquel S Carreira
    BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 6:462-72. 2010
  4. pmc Impaired mitophagy at the heart of injury
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 7:1573-4. 2011
  5. pmc Autophagy: an affair of the heart
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Heart Fail Rev 18:575-84. 2013
  6. pmc Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice
    Chengqun Huang
    San Diego State University, BioScience Center and Department of Biology, CA, USA
    Circulation 121:675-83. 2010

Collaborators

  • Robert M Mentzer
  • Asa B Gustafsson
  • Chengqun Huang
  • Michael A Gurney
  • Jennifer M Ramil
  • Raquel S Carreira
  • Youngil Lee
  • Allen M Andres
  • Nandini Ravindran
  • Jon Sin
  • Phyllis Jean Linton
  • Natalie A Gude
  • Mark A Sussman
  • Shivaji Rikka
  • Patricia A Thistlethwaite
  • Mariam Ghochani
  • Xiaoxue Zhang
  • Lucy Kim

Detail Information

Publications6

  1. pmc Cardioprotection through autophagy: ready for clinical trial?
    Roberta A Gottlieb
    Radical Therapeutix, Inc, Solana Beach, CA, USA
    Autophagy 7:434-5. 2011
    ..Since 2005 several studies have implicated autophagy as a target for cardioprotection...
  2. doi Measuring cardiac autophagic flux in vitro and in vivo
    Michael A Gurney
    Donald P Shiley BioScience Center, San Diego State University, 5500 Campanile Dr, San Diego, CA, 92182 4650, USA
    Methods Mol Biol 1219:187-97. 2015
    ..Here, we describe a method for determining autophagic flux in vitro and in vivo using the autophagosomal/lysosomal fusion inhibitors chloroquine or bafilomycin A1 and then probing for the autophagosomal marker LC3-II via Western Blot...
  3. pmc Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
    Raquel S Carreira
    BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 6:462-72. 2010
    ..Starvation-induced autophagy regulated by CypD and the MPT may represent a homeostatic mechanism for cellular and mitochondrial quality control...
  4. pmc Impaired mitophagy at the heart of injury
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 7:1573-4. 2011
    ..The field is in need of methods to monitor mitochondrial turnover in vivo to support the development of new therapies targeting mitochondrial turnover...
  5. pmc Autophagy: an affair of the heart
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Heart Fail Rev 18:575-84. 2013
    ..Contradictory findings are reconciled in light of recent developments. The preponderance of evidence favors a beneficial role for autophagy in the heart under most conditions. ..
  6. pmc Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice
    Chengqun Huang
    San Diego State University, BioScience Center and Department of Biology, CA, USA
    Circulation 121:675-83. 2010
    ..To date, very little is known about the mechanism of this late-onset cardiotoxicity...