David Gosal

Summary

Publications

  1. ncbi Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD
    David Gosal
    Department of Neurology, Mater Misericordiae Hospital, Eccles St, Dublin 7, Ireland
    Parkinsonism Relat Disord 11:349-52. 2005
  2. ncbi Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish
    Owen A Ross
    Department of Geriatric Medicine, Belfast, Ireland
    Hum Immunol 65:340-6. 2004
  3. ncbi Parkinson's disease in Ireland: clinical presentation and genetic heterogeneity in patients with parkin mutations
    Joseph Wiley
    University College Dublin Conway Institute of Biomolecular and Biomedical Research, Department of Neurology, Mater Misericordiae Hospital, Ireland
    Mov Disord 19:677-81. 2004
  4. ncbi Global distribution and reduced penetrance: Lrrk2 R1441C in an Irish Parkinson's disease kindred
    David Gosal
    Mov Disord 22:291-2. 2007
  5. pmc Genomewide association, Parkinson disease, and PARK10
    Matthew J Farrer
    Am J Hum Genet 78:1084-8; author reply 1092-4. 2006
  6. pmc Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease
    Owen A Ross
    Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
    Mech Ageing Dev 128:378-82. 2007

Collaborators

Detail Information

Publications6

  1. ncbi Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD
    David Gosal
    Department of Neurology, Mater Misericordiae Hospital, Eccles St, Dublin 7, Ireland
    Parkinsonism Relat Disord 11:349-52. 2005
    ..The influence of the G2019S substitution on protein function and disease phenotype has yet to be fully resolved, but its elucidation will undoubtedly further our understanding of the mechanisms underlying Parkinson's disease...
  2. ncbi Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish
    Owen A Ross
    Department of Geriatric Medicine, Belfast, Ireland
    Hum Immunol 65:340-6. 2004
    ....
  3. ncbi Parkinson's disease in Ireland: clinical presentation and genetic heterogeneity in patients with parkin mutations
    Joseph Wiley
    University College Dublin Conway Institute of Biomolecular and Biomedical Research, Department of Neurology, Mater Misericordiae Hospital, Ireland
    Mov Disord 19:677-81. 2004
    ..Mutations in the parkin gene may account for approximately 17% of early-onset (age at onset <45 years) parkinsonism in Ireland, in agreement with previous European studies...
  4. ncbi Global distribution and reduced penetrance: Lrrk2 R1441C in an Irish Parkinson's disease kindred
    David Gosal
    Mov Disord 22:291-2. 2007
  5. pmc Genomewide association, Parkinson disease, and PARK10
    Matthew J Farrer
    Am J Hum Genet 78:1084-8; author reply 1092-4. 2006
  6. pmc Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease
    Owen A Ross
    Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
    Mech Ageing Dev 128:378-82. 2007
    ..It is now crucial to identify the susceptibility allele and elucidate its functionality which may generate a therapeutic target for PD...