Gregory S Gorman

Summary

Publications

  1. ncbi request reprint In-vitro and in-vivo metabolic studies of the candidate chemopreventative pentamethylchromanol using liquid chromatography/tandem mass spectrometry
    Gregory S Gorman
    Toxicology and Bioanalytical Science Department, Southern Research Institute, Birmingham, AL 35205, USA
    J Pharm Pharmacol 61:1309-18. 2009
  2. ncbi request reprint In vitro metabolic characterization, phenotyping, and kinetic studies of 9cUAB30, a retinoid X receptor-specific retinoid
    Gregory S Gorman
    Southern Research Institute, Birmingham, Alabama 35205, USA
    Drug Metab Dispos 35:1157-64. 2007
  3. doi request reprint Effects of herbal supplements on the bioactivation of chemotherapeutic agents
    Gregory S Gorman
    McWhorter School of Pharmacy, Samford University, Birmingham, AL 35229, USA
    J Pharm Pharmacol 65:1014-25. 2013
  4. pmc 13C enrichment of carbons 2 and 8 of purine by folate-dependent reactions after [13C]formate and [2-13C]glycine dosing in adult humans
    Joseph E Baggott
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Metabolism 56:708-15. 2007

Collaborators

  • Joseph E Baggott
  • Tsunenobu Tamura

Detail Information

Publications4

  1. ncbi request reprint In-vitro and in-vivo metabolic studies of the candidate chemopreventative pentamethylchromanol using liquid chromatography/tandem mass spectrometry
    Gregory S Gorman
    Toxicology and Bioanalytical Science Department, Southern Research Institute, Birmingham, AL 35205, USA
    J Pharm Pharmacol 61:1309-18. 2009
    ..Additional investigations compare in-vitro data with in-vivo metabolic data from rats and dogs...
  2. ncbi request reprint In vitro metabolic characterization, phenotyping, and kinetic studies of 9cUAB30, a retinoid X receptor-specific retinoid
    Gregory S Gorman
    Southern Research Institute, Birmingham, Alabama 35205, USA
    Drug Metab Dispos 35:1157-64. 2007
    ..Kinetic analysis of eight of the detected metabolites indicated that four seemed to follow classical hyperbolic kinetics, whereas the remaining four showed evidence of either autoactivation or substrate inhibition...
  3. doi request reprint Effects of herbal supplements on the bioactivation of chemotherapeutic agents
    Gregory S Gorman
    McWhorter School of Pharmacy, Samford University, Birmingham, AL 35229, USA
    J Pharm Pharmacol 65:1014-25. 2013
    ..The aim of this study was to investigate the impact of commercially available, over-the-counter herbal supplements (St John's wort, black cohosh and ginger root extract) on the metabolic activation of tamoxifen and irinotecan...
  4. pmc 13C enrichment of carbons 2 and 8 of purine by folate-dependent reactions after [13C]formate and [2-13C]glycine dosing in adult humans
    Joseph E Baggott
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Metabolism 56:708-15. 2007
    ..Possible mechanisms explaining our findings are discussed. Oral [(13)C]formate or [2-(13)C]glycine dosing and urine collection can be used to study purine biosynthesis in humans...