Bipolar depression: a review of randomised clinical trialsPaul J Goodnick
Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Carrier Clinic, POB 147, 252 CR 601, Belle Mead, NJ 08502, USA
Expert Opin Pharmacother 8:13-21. 2007
..All antidepressants present with some risk for induction of mania and/or cycle acceleration and are best used in combination with mood stablisers; greatest risk for destabilisation seems to be with venlafaxine...
Mirtazapine in major depression with comorbid generalized anxiety disorderP J Goodnick
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Fla 33136, USA
J Clin Psychiatry 60:446-8. 1999
..Because of mirtazapine's early anxiolytic effects, the present study was undertaken as a preliminary investigation in patients with a diagnosis of major depression with comorbid GAD...
Anticonvulsants in the treatment of bipolar maniaPaul J Goodnick
Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Carrier Clinic, PO Box 147, Belle Mead, NJ 08502, USA
Expert Opin Pharmacother 7:401-10. 2006
..A review of the kinetics, side effects and complications of the antiepileptic drugs indicates that carbamazepine is useful, and has adverse event benefit over all other options. The potential of zonisamide awaits further testing...
Higher than Physician's Desk Reference (US) doses on atypical antipsychoticsPaul J Goodnick
Department of Psychiatry and Behavioural Sciences, Carrier Clinic, UMDNJ Robert Wood Johnson School of Medicine, 252 CR 601, Belle Mead, NJ 08502, USA
Expert Opin Drug Saf 4:653-68. 2005
..Reports above those doses are included, but either are insufficient in numbers or bring up questions on safety. In many situations, feared increase in adverse events were not magnified by use of higher doses...
Aripiprazole: profile on efficacy and safetyPaul J Goodnick
D79, University of Miami School of Medicine, 1400 NW 10 Avenue, Ste 304A, Miami, FL 33136, USA
Expert Opin Pharmacother 3:1773-81. 2002
..Finally, results also support the proposition that aripiprazole may lead to reductions in corrected QT interval and have minimal drug interactions...
Antipsychotics: impact on prolactin levelsPaul J Goodnick
Department of Psychiatry and Behavioural Sciences, University of Miami School of Medicine, 1400 NW 10 Avenue, Ste 304A, Miami, FL 33136, USA
Expert Opin Pharmacother 3:1381-91. 2002
..Most recently, aripiprazole, in early studies, appears to produce significant reductions in hPrl while maintaining therapeutic efficacy for psychosis...
Psychotropic drugs and the ECG: focus on the QTc intervalPaul J Goodnick
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, D79, 1400 NW 10 Avenue, Ste 304A, Miami, Florida 33162, USA
Expert Opin Pharmacother 3:479-98. 2002
..What is available concerning lithium, the anticonvulsants and the benzodiazepines indicates little effect on the QTc, although there may be effects on other cardiovascular parameters...
Ziprasidone: profile on safetyP J Goodnick
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, 1400 NW 10 Avenue, Ste 304A, Mail Code D79, Miami, Florida 33136, USA
Expert Opin Pharmacother 2:1655-62. 2001
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Antipsychotic medication: effects on regulation of glucose and lipidsM M Kato
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, 1400 NW 10 Avenue, Ste 304A, Miami, FL 33136, USA
Expert Opin Pharmacother 2:1571-82. 2001
..Ziprasidone appears to be the antipsychotic with the most beneficial combination of effects: no weight gain, no change in glucose utilisation and reductions in cholesterol and serum triglycerides (TGs)...
Vagus nerve stimulation in depressionP J Goodnick
University of Miami School of Medicine, FL 33136, USA
Expert Opin Pharmacother 2:1061-3. 2001
..These results have led to approval of VNS for the treatment of resistant depression (unipolar or bipolar) in both Europe and Canada. Currently, a pivotal double-blind acute study is underway in the US...
Treatment of depression in comorbid medical illnessP J Goodnick
Department of Psychiatry and Behavioral Sciences, D79, 1400 NW 10 Avenue, Ste 304A, Miami, FL 33136, USA
Expert Opin Pharmacother 1:1367-84. 2000
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Summary from the 153rd meeting of the American Psychiatric Association. 13-18 May 2000, Chicago, Illinois, USAP J Goodnick
University of Miami, Department of Psychiatry and Behavioural Sciences, Miami, FL, USA
Expert Opin Pharmacother 1:1067-9. 2000
..The latest developments are typically those found in the New Research sections, which is where this summary will focus...
Women's issues in mood disordersP J Goodnick
Department of Psychiatry and Behavioural Sciences, University of Miami, School of Medicine, D79, 1400 NW 10 Avenue, Ste 304A, Miami, FL 33136, USA
Expert Opin Pharmacother 1:903-16. 2000
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Seligiline transdermal system in depressionPaul J Goodnick
Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Carrier Clinic, POB 147, 252 CR 601, Belle Mead, NJ 08502, USA
Expert Opin Pharmacother 8:59-64. 2007
..This is generally a time period of 1 week. Upon stopping treatment with selegiline, 2 weeks should pass prior to beginning any medication at risk for drug interactions...
The use of nimodipine in the treatment of mood disordersP J Goodnick
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, FL 33136, USA
Bipolar Disord 2:165-73. 2000
..g., ultra-rapid-cycling bipolars and brief recurrent depressions...
Use of olanzapine in non-psychotic psychiatric disordersP J Goodnick
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, D79, 1400 NW 10 Avenue, Miami, Florida 33136, USA
Expert Opin Pharmacother 2:667-80. 2001
..In each of these latter diagnoses, double-blind studies are either underway or are planned to establish efficacy...
Use of antidepressants in treatment of comorbid diabetes mellitus and depression as well as in diabetic neuropathyP J Goodnick
Department of Psychiatry, University of Miami School of Medicine, Florida 33136, USA
Ann Clin Psychiatry 13:31-41. 2001
..In diabetic neuropathy without depression, the best choices among non-TCAs may include sertraline, citalopram, and perhaps, venlafaxine, since the TCAs appear to increase cravings and increase FBG levels...
Rapid cycling bipolar disorderC Barrios
Department of Psychiatry and Behavioural Sciences, University of Miami School of Medicine, D79, 1400 NW 10 Avenue, Ste 304A, Miami, FL 33136, USA
Expert Opin Pharmacother 2:1963-73. 2001
..More research is needed into the possible therapeutic benefits of verapamil, bupropion, choline, light therapy and electroconvulsive therapy (ECT)...
The effectiveness of St. John's Wort in major depressive disorder: a naturalistic phase 2 follow-up in which nonresponders were provided alternate medicationAlan J Gelenberg
University of Arizona Health Sciences Center, Tucson, AZ 85724, USA
J Clin Psychiatry 65:1114-9. 2004
..A continuation study of an extract of St. John's wort (Hypericum perforatum) for depression was performed in follow-up to an acute study that found no significant difference between St. John's wort extract and placebo...