Rose E Goodchild

Summary

Publications

  1. Goodchild R, Buchwalter A, Naismith T, Holbrook K, Billion K, Dauer W, et al. Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum. J Cell Sci. 2015;128:2854-65 pubmed publisher
    ..These data suggest that LULL1 oligomerizes to engage and transiently disassemble torsinA oligomers, and is thereby positioned to transduce cytoplasmic signals to the INM through torsinA. ..
  2. Lauwers E, Goodchild R, Verstreken P. Membrane Lipids in Presynaptic Function and Disease. Neuron. 2016;90:11-25 pubmed publisher
    ..This insight highlights that presynaptic terminals are membrane-remodeling machines and that cooperation between lipid and protein molecules underlies presynaptic activity. ..
  3. Grillet M, Dominguez Gonzalez B, Sicart A, Pöttler M, Cascalho A, Billion K, et al. Torsins Are Essential Regulators of Cellular Lipid Metabolism. Dev Cell. 2016;38:235-47 pubmed publisher
    ..These findings identify that torsins are essential regulators of cellular lipid metabolism and implicate disturbed lipid biology in childhood-onset DYT1 dystonia. ..