Surgical treatment for early osteoarthritis. Part I: cartilage repair proceduresA H Gomoll
Cartilage Repair Center, Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, MA, USA
Knee Surg Sports Traumatol Arthrosc 20:450-66. 2012
..This review of cartilage repair techniques will discuss currently available procedures, specifically pertaining to experiences in the setting of early OA. Level of evidence IV...
Surgical treatment for early osteoarthritis. Part II: allografts and concurrent proceduresA H Gomoll
Cartilage Repair Center, Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, MA, USA
Knee Surg Sports Traumatol Arthrosc 20:468-86. 2012
..LEVEL OF EVIDENCE: Systematic review, Level II...
Use of a type I/III bilayer collagen membrane decreases reoperation rates for symptomatic hypertrophy after autologous chondrocyte implantationAndreas H Gomoll
Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 850 Boylston Street, Chestnut Hill, MA 02467, USA
Am J Sports Med 37:20S-23S. 2009
..This multicenter study investigates the off-label use of 1 collagen membrane as a periosteal substitute for autologous chondrocyte implantation...
Nanoparticulate fillers improve the mechanical strength of bone cementAndreas H Gomoll
Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Acta Orthop 79:421-7. 2008
..We investigated a new composite with the well characterized chemical composition of current cements, but with nanoparticles instead of the conventional, micrometer-size barium sulfate radiopacifier...
Individual skill progression on a virtual reality simulator for shoulder arthroscopy: a 3-year follow-up studyAndreas H Gomoll
Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Am J Sports Med 36:1139-42. 2008
..Additional longitudinal studies are necessary to confirm the validity of virtual reality simulation before these teaching aids can be more fully recommended for surgical education...
Autologous chondrocyte implantation for joint preservation in patients with early osteoarthritisTom Minas
Cartilage Repair Center, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Clin Orthop Relat Res 468:147-57. 2010
..LEVEL OF EVIDENCE: Level IV, case series. See Guidelines for Authors for a complete description of levels of evidence...
Increased failure rate of autologous chondrocyte implantation after previous treatment with marrow stimulation techniquesTom Minas
Cartilage Repair Center, Brigham and Women s Hospital, Harvard Medical School, 850 Boylston Street, Chestnut Hill, MA 02467, USA
Am J Sports Med 37:902-8. 2009
..Common knowledge holds that these treatments do not compromise subsequent cartilage repair procedures with autologous chondrocyte implantation...
Treatment of chondral defects in the patellofemoral jointAndreas H Gomoll
Cartilage Repair Center, Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, MA, USA
J Knee Surg 19:285-95. 2006
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Triad of cartilage restoration for unicompartmental arthritis treatment in young patients: meniscus allograft transplantation, cartilage repair and osteotomyAndreas H Gomoll
Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
J Knee Surg 22:137-41. 2009
..Combined treatment with meniscal transplantation, cartilage repair, and osteotomy demonstrated promising clinical results of unicompartmental arthritis treatment in young patients...
Repair of large chondral defects of the knee with autologous chondrocyte implantation in patients 45 years or olderRalf E Rosenberger
Cartilage Repair Center, Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Sports Med 36:2336-44. 2008
..Current recommendations limit this procedure to younger patients, as insufficient data are available to conclusively evaluate outcomes in patients older than 45 years...
A review of the evaluation and management of cartilage defects in the kneeR Frank Henn
Cartilage Repair Center, Brigham and Women s Hospital, Chestnut Hill, MA
Phys Sportsmed 39:101-7. 2011
..This article describes an approach to the evaluation and management of cartilage defects of the knee...
Microfracture and augmentsAndreas H Gomoll
Department of Orthopaedic Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Knee Surg 25:9-15. 2012
..Augmentation techniques discussed include collagen and polymer membranes, chitosan and fibrin gels, hyaluronan injections, as well as numerous growth factors...
Long-term effects of bupivacaine on cartilage in a rabbit shoulder modelAndreas H Gomoll
Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Sports Med 37:72-7. 2009
..This study was designed to provide additional information on the long-term effects of bupivacaine infusion on articular cartilage in an established rabbit shoulder model...
Effect on ligament marker expression by direct-contact co-culture of mesenchymal stem cells and anterior cruciate ligament cellsJose A Canseco
Department of Anesthesiology, Laboratory for Tissue Engineering and Regenerative Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts, USA
Tissue Eng Part A 18:2549-58. 2012
..Thus, we conclude that using a 50% co-culture of ACLcs and MSCs, instead of either cell population alone, may better maintain or even enhance ligament marker expression and improve healing...
Internal fixation of unstable Cahill Type-2C osteochondritis dissecans lesions of the knee in adolescent patientsAndreas H Gomoll
Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, Mass, USA
Orthopedics 30:487-90. 2007
..This technique is appropriate and efficacious for the treatment of unstable osteochondritis dissecans lesions...
Advances in arthroscopic surgery: indications and outcomesJeffrey N Katz
Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Curr Opin Rheumatol 19:106-10. 2007
..The review is particularly timely given the rapidly expanding range of indications for diagnostic and therapeutic arthroscopic procedures involving virtually every peripheral joint...
Surgical experience correlates with performance on a virtual reality simulator for shoulder arthroscopyAndreas H Gomoll
Department of Orthopaedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Sports Med 35:883-8. 2007
..As with any new educational tool, these devices have generated controversy about the validity of the training experience...
The subchondral bone in articular cartilage repair: current problems in the surgical managementAndreas H Gomoll
Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Chestnut Hill, MA 02467, USA
Knee Surg Sports Traumatol Arthrosc 18:434-47. 2010
..Lastly, since this area remains in constant evolution, the requirements for prospective studies needed to evaluate these emerging technologies will be reviewed...
Surgical management of articular cartilage defects of the kneeAndreas H Gomoll
Brigham and Women s Hospital, Boston, MA, USA
Instr Course Lect 60:461-83. 2011
..It is important to examine treatment recommendations from the current literature and understand surgical techniques for articular cartilage repair...
High tibial osteotomy for the treatment of unicompartmental knee osteoarthritis: a review of the literature, indications, and techniqueAndreas H Gomoll
Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Chestnut Hill, MA, USA
Phys Sportsmed 39:45-54. 2011
..This article provides an overview of the indications, technique, complications, and outcomes of high tibial osteotomy, specifically the more commonly used opening wedge technique...
Lubricin distribution in the torn human anterior cruciate ligament and meniscusDafang Zhang
Harvard Medical School, Boston, Massachusetts 02115, USA
J Orthop Res 29:1916-22. 2011
..In all tissues, lubricin was found in the matrix and intracellularly. The surface layer of lubricin coating torn edges of ACLs and menisci may interfere with the integrative healing process needed for repair...
Biocompatibility of a polymer patch for rotator cuff repairBrian J Cole
Department of Orthopedics and Anatomy and Cell Biology, Rush University Medical Center, Rush Medical College, Chicago, IL 60612, USA
Knee Surg Sports Traumatol Arthrosc 15:632-7. 2007
..9%. In conclusion, the polycarbonate polyurethane patch for tissue extension or augmentation in rotator cuff repair has demonstrated no inflammatory response and excellent tissue integration in a rat rotator cuff repair model...