sobhi gomha

Summary

Affiliation: Chemistry Department, Faculty of Science, Cairo University
Location: cairo, egypt

Publications

  1. ncbi request reprint Formate assay in body fluids: application in methanol poisoning
    A B Makar
    Biochem Med 13:117-26. 1975
  2. doi request reprint Synthesis and cytotoxicity evaluation of some novel thiazoles, thiadiazoles, and pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones incorporating triazole moiety
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Molecules 20:1357-76. 2015
  3. doi request reprint Identification of novel aminothiazole and aminothiadiazole conjugated cyanopyridines as selective CHK1 inhibitors
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt Electronic address
    Eur J Med Chem 92:459-70. 2015
  4. doi request reprint Diphenylpyrroles: Novel p53 activators
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt Electronic address
    Eur J Med Chem 82:472-9. 2014
  5. ncbi request reprint 3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno [2,3-d]pyrimidine: an effecient key precursor for novel synthesis of some interesting triazines and triazepines as potential anti-tumor agents
    Mohamed G Badrey
    Chemistry Department, Faculty of Science, Fayoum University, El Fayoum, 63514, Egypt
    Molecules 17:11538-53. 2012
  6. doi request reprint A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Egypt
    Molecules 17:9335-47. 2012
  7. doi request reprint Synthesis and antimicrobial activity of some new pyrazoles, fused pyrazolo[3,4-d]-pyrimidine and 1,2-dihydroimidazo-[2,1-c][1,2,4]triazin-6-one derivatives
    Sobhi Mohamed Gomha
    Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Egypt
    Molecules 16:6549-60. 2011
  8. doi request reprint Synthesis under microwave irradiation of [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazoles and other diazoles bearing indole moieties and their antimicrobial evaluation
    Sobhi M Gomha
    Department of Chemistry, University of Cairo, Giza 12613, Egypt
    Molecules 16:8244-56. 2011

Collaborators

  • Mohamed G Badrey
  • A B Makar
  • K E McMartin
  • M Palese
  • T R Tephly

Detail Information

Publications8

  1. ncbi request reprint Formate assay in body fluids: application in methanol poisoning
    A B Makar
    Biochem Med 13:117-26. 1975
  2. doi request reprint Synthesis and cytotoxicity evaluation of some novel thiazoles, thiadiazoles, and pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones incorporating triazole moiety
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Molecules 20:1357-76. 2015
    ..19, and 3.4 ┬ÁM, respectively). ..
  3. doi request reprint Identification of novel aminothiazole and aminothiadiazole conjugated cyanopyridines as selective CHK1 inhibitors
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt Electronic address
    Eur J Med Chem 92:459-70. 2015
    ....
  4. doi request reprint Diphenylpyrroles: Novel p53 activators
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt Electronic address
    Eur J Med Chem 82:472-9. 2014
    ....
  5. ncbi request reprint 3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno [2,3-d]pyrimidine: an effecient key precursor for novel synthesis of some interesting triazines and triazepines as potential anti-tumor agents
    Mohamed G Badrey
    Chemistry Department, Faculty of Science, Fayoum University, El Fayoum, 63514, Egypt
    Molecules 17:11538-53. 2012
    ..Finally, the antitumor activity of the new compounds 4a and 8a against human breast cell MCF-7 line and liver carcinoma cell line HepG2 were recorded...
  6. doi request reprint A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity
    Sobhi M Gomha
    Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Egypt
    Molecules 17:9335-47. 2012
    ..Also, the cytototoxic activities of the thiazole derivative 5a was evaluated against HaCaT cells (human keratinocytes). It was found that compound 5a possess potent cytotoxic activity...
  7. doi request reprint Synthesis and antimicrobial activity of some new pyrazoles, fused pyrazolo[3,4-d]-pyrimidine and 1,2-dihydroimidazo-[2,1-c][1,2,4]triazin-6-one derivatives
    Sobhi Mohamed Gomha
    Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Egypt
    Molecules 16:6549-60. 2011
    ..The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, 1H-NMR and mass spectral data. The antifungal and antibacterial activities of the newly synthesized compounds were evaluated...
  8. doi request reprint Synthesis under microwave irradiation of [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazoles and other diazoles bearing indole moieties and their antimicrobial evaluation
    Sobhi M Gomha
    Department of Chemistry, University of Cairo, Giza 12613, Egypt
    Molecules 16:8244-56. 2011
    ..The structures of the synthesized compounds were assigned based on elemental analyses and spectral data (IR, (1)H-NMR, (13)C-NMR, MS). The antifungal and antibacterial activities of the new products were also evaluated...