Marcus Vinicius Gomes
Gomes M, Pelosi G. Epigenetic vulnerability and the environmental influence on health. Exp Biol Med (Maywood). 2013;238:859-65 pubmed publisher
Rodrigues G, Toffoli L, Manfredo M, Francis Oliveira J, Silva A, Raquel H, et al
. Acute stress affects the global DNA methylation profile in rat brain: modulation by physical exercise. Behav Brain Res. 2015;279:123-8 pubmed publisher
..Furthermore, our evidence indicates that physical exercise has the potential to modulate changes in DNA methylation and gene expression consequent to ARS. ..
Kashimoto R, Toffoli L, Manfredo M, Volpini V, Martins Pinge M, Pelosi G, et al
. Physical exercise affects the epigenetic programming of rat brain and modulates the adaptive response evoked by repeated restraint stress. Behav Brain Res. 2016;296:286-289 pubmed publisher
..In summary, our data indicate that physical exercise affects DNA methylation of the hypothalamus and might modulate epigenetic responses evoked by RRS in the hippocampus, cortex, and hypothalamus. ..
Gomes M, Manfredo M, Toffoli L, Castro Alves D, do Nascimento L, da Silva W, et al
. Effects of the led therapy on the global DNA methylation and the expression of Dnmt1 and Dnmt3a genes in a rat model of skin wound healing. Lasers Med Sci. 2016;31:1521-6 pubmed publisher
..6 J/cm(2) of LED evokes an increase in the expression of the Dnmt3a that might associates to the efficiency of the epithelial wound healing. ..
VerÃssimo L, Volpini V, Estrada V, Matsubara N, Gomes M, Resstel L, et al
. Treatment with escitalopram modulates cardiovascular function in rats. Eur J Pharmacol. 2018;824:120-127 pubmed publisher
..These findings showed that despite the escitalopram be a relatively safe drug it can cause tonic effects on cardiovascular function as well as during aversive situations. ..
Gomes M, Borges K, Moreno D, Queiroz R, Machado H, Carlotti C, et al
. Abnormal methylation of histone deacetylase genes: implications on etiology and epigenetic therapy of astrocytomas. Anticancer Res. 2011;31:1337-43 pubmed
Gomes M, Toffoli L, Arruda D, Soldera L, Pelosi G, Neves Souza R, et al
. Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities. PLoS ONE. 2012;7:e52570 pubmed publisher
Toffoli L, Volpini V, Nascimento L, Silva W, Verissimo L, Estrada V, et al
. Effects of chronic restraint stress on the global DNA methylation profile of rat lung cells: Modulation by physical exercise. Behav Brain Res. 2017;331:188-192 pubmed publisher
..Our data showed that behavioral stress induced significant changes in the DNA methylation profile of rat lung cells and that this could be modulated by physical exercise. ..