Chern Sing Goh

Summary

Publications

  1. pmc Integration of curated databases to identify genotype-phenotype associations
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA
    BMC Genomics 7:257. 2006
  2. pmc SPINE 2: a system for collaborative structural proteomics within a federated database framework
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520, USA
    Nucleic Acids Res 31:2833-8. 2003
  3. ncbi request reprint Conformational changes associated with protein-protein interactions
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520, USA
    Curr Opin Struct Biol 14:104-9. 2004
  4. ncbi request reprint Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Ave, New Haven, CT 06520, USA
    J Mol Biol 336:115-30. 2004
  5. pmc An integrative genomic approach to uncover molecular mechanisms of prokaryotic traits
    Yang Liu
    Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America
    PLoS Comput Biol 2:e159. 2006

Detail Information

Publications5

  1. pmc Integration of curated databases to identify genotype-phenotype associations
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA
    BMC Genomics 7:257. 2006
    ....
  2. pmc SPINE 2: a system for collaborative structural proteomics within a federated database framework
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520, USA
    Nucleic Acids Res 31:2833-8. 2003
    ..g. crystallization LIMS local to particular laboratories) and (iii) international archival resources that SPINE links to and passes on information to (e.g. TargetDB at the PDB)...
  3. ncbi request reprint Conformational changes associated with protein-protein interactions
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520, USA
    Curr Opin Struct Biol 14:104-9. 2004
    ..However, there is increasing support for the pre-existing equilibrium model, whereby proteins are found to simultaneously exist in populations of diverse conformations...
  4. ncbi request reprint Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Ave, New Haven, CT 06520, USA
    J Mol Biol 336:115-30. 2004
    ..This information may prove useful in optimizing high-throughput experimentation. Further information is available from http://mining.nesg.org/...
  5. pmc An integrative genomic approach to uncover molecular mechanisms of prokaryotic traits
    Yang Liu
    Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America
    PLoS Comput Biol 2:e159. 2006
    ..We propose that this method elucidates which classes of molecular mechanisms are associated with phenotypes or metaphenotypes and holds promise in facilitating a computable systems biology approach to genomic and biomedical research...