Patrick Gladding

Summary

Publications

  1. doi request reprint Pharmacogenetic testing for clopidogrel using the rapid INFINITI analyzer: a dose-escalation study
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    JACC Cardiovasc Interv 2:1095-101. 2009
  2. doi request reprint The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    JACC Cardiovasc Interv 1:620-7. 2008
  3. ncbi request reprint Prasugrel, Māori, and personalised medicine in New Zealand
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Private Bag 92024, Victoria St West, Auckland 1142, New Zealand
    N Z Med J 123:86-90. 2010
  4. doi request reprint The cost effectiveness of genetic testing for CYP2C19 variants to guide thienopyridine treatment in patients with acute coronary syndromes: a New Zealand evaluation
    Laura Panattoni
    School of Population Health, University of Auckland, Auckland, New Zealand
    Pharmacoeconomics 30:1067-84. 2012
  5. doi request reprint Antiplatelet drug nonresponsiveness
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Am Heart J 155:591-9. 2008
  6. doi request reprint The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel: the PRINC (Plavix Response in Coronary Intervention) trial
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    JACC Cardiovasc Interv 1:612-9. 2008
  7. doi request reprint Trans-fatty acids in New Zealand patients with coronary artery disease
    Jocelyne R Benatar
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Eur J Cardiovasc Prev Rehabil 18:615-20. 2011

Detail Information

Publications7

  1. doi request reprint Pharmacogenetic testing for clopidogrel using the rapid INFINITI analyzer: a dose-escalation study
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    JACC Cardiovasc Interv 2:1095-101. 2009
    ..Our aim was to assess whether a higher clopidogrel maintenance dose has a greater antiplatelet effect in CYP2C19*2 allele carriers compared with noncarriers...
  2. doi request reprint The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    JACC Cardiovasc Interv 1:620-7. 2008
    ..This study assessed the effect of pharmacogenetics on the antiplatelet effect of clopidogrel...
  3. ncbi request reprint Prasugrel, Māori, and personalised medicine in New Zealand
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Private Bag 92024, Victoria St West, Auckland 1142, New Zealand
    N Z Med J 123:86-90. 2010
    ..A demonstration of the cost-effectiveness of genetic testing, on a population basis, and a proven alternative, personalised strategy is required before the adoption of this technology can be advocated...
  4. doi request reprint The cost effectiveness of genetic testing for CYP2C19 variants to guide thienopyridine treatment in patients with acute coronary syndromes: a New Zealand evaluation
    Laura Panattoni
    School of Population Health, University of Auckland, Auckland, New Zealand
    Pharmacoeconomics 30:1067-84. 2012
    ..The frequency of the *2 allele varies by ethnicity and the Maoris, Asians and Pacific Islanders of New Zealand have a relatively high incidence...
  5. doi request reprint Antiplatelet drug nonresponsiveness
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Am Heart J 155:591-9. 2008
    ..This review article reviews the background, mechanisms, and evidence in support of the clinical significance of this phenomenon...
  6. doi request reprint The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel: the PRINC (Plavix Response in Coronary Intervention) trial
    Patrick Gladding
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    JACC Cardiovasc Interv 1:612-9. 2008
    ..This study evaluated the antiplatelet effect of a higher loading and maintenance dose regimen of clopidogrel and a possible drug interaction with verapamil...
  7. doi request reprint Trans-fatty acids in New Zealand patients with coronary artery disease
    Jocelyne R Benatar
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Eur J Cardiovasc Prev Rehabil 18:615-20. 2011
    ..This observational cross-sectional study in New Zealand patients with surgical coronary artery disease assesses the plasma levels of TFA and the association of TFA levels with clinical markers of vascular disease...