Christian Gilissen

Summary

Publications

  1. Lelieveld S, Veltman J, Gilissen C. Novel bioinformatic developments for exome sequencing. Hum Genet. 2016;135:603-14 pubmed publisher
    ..With these developments, exome sequencing is paving the way for the next big challenge, the application of whole genome sequencing. ..
  2. Goldmann J, Seplyarskiy V, Wong W, Vilboux T, Neerincx P, Bodian D, et al. Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence. Nat Genet. 2018;50:487-492 pubmed publisher
    ..This result suggested accumulation of DSB-induced mutations throughout oocyte aging as the mechanism underlying the formation of maternal mutation clusters. ..
  3. Lelieveld S, Wiel L, Venselaar H, Pfundt R, Vriend G, Veltman J, et al. Spatial Clustering of de Novo Missense Mutations Identifies Candidate Neurodevelopmental Disorder-Associated Genes. Am J Hum Genet. 2017;101:478-484 pubmed publisher