M Ghanei

Summary

Publications

  1. pmc Angiotensin-converting enzyme genotype and late respiratory complications of mustard gas exposure
    Ali Reza Hosseini-Khalili
    UCL Institute for Human Health and Performance, Ground Floor, Charterhouse Building, UCL Archway Campus, Highgate Hill, Archway, London N19 5LW, UK
    BMC Pulm Med 8:15. 2008
  2. ncbi request reprint Distal esophagitis in patients with mustard-gas induced chronic cough
    M Ghanei
    Research Center for Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Dis Esophagus 19:285-8. 2006
  3. ncbi request reprint Sinus CT scan findings in patients with chronic cough following sulfur mustard inhalation: a case-control study
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Tehran, Iran
    Inhal Toxicol 18:1135-8. 2006
  4. ncbi request reprint Mounier-Kuhn syndrome: a rare cause of severe bronchial dilatation with normal pulmonary function test: a case report
    Mostafa Ghanei
    Pulmonologist, Baqiyatallah University of Medical Sciences, Mollasadra Street, Tehran, Iran
    Respir Med 101:1836-9. 2007
  5. ncbi request reprint Clinical differentiation between resistant asthma and chronic bronchiolitis: testing a practical approach
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Research Center of Chemical Injuries, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:207-14. 2007
  6. doi request reprint An international collaborative pathologic study of surgical lung biopsies from mustard gas-exposed patients
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Mollasadra Street, PO Box 19945 546, Tehran, Iran
    Respir Med 102:825-30. 2008
  7. doi request reprint Noninvasive diagnosis of bronchiolitis obliterans due to sulfur mustard exposure: could high-resolution computed tomography give us a clue?
    M Ghanei
    Chemical Injuries Research Center, Baqiyatallah University of Medical Science, Mollasadra Ave, 14359 16471, Tehran, Iran
    Radiol Med 115:413-20. 2010
  8. doi request reprint Overexpression of transforming growth factor (TGF)-beta1 and TGF-beta3 genes in lung of toxic-inhaled patients
    Aref Arzan Zarin
    Department of Genetics, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran
    Exp Lung Res 36:284-91. 2010
  9. ncbi request reprint Therapeutics effect of N-acetyl cysteine on mustard gas exposed patients: evaluating clinical aspect in patients with impaired pulmonary function test
    Majid Shohrati
    Research Center of Chemical Injuries, Baqyatallah Medical Sciences University, Mollasadra Street, P O Box 19945 546, Tehran, Iran
    Respir Med 102:443-8. 2008
  10. ncbi request reprint Long term consequences from exposure to sulfur mustard: a review
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Inhal Toxicol 19:451-6. 2007

Collaborators

Detail Information

Publications40

  1. pmc Angiotensin-converting enzyme genotype and late respiratory complications of mustard gas exposure
    Ali Reza Hosseini-Khalili
    UCL Institute for Human Health and Performance, Ground Floor, Charterhouse Building, UCL Archway Campus, Highgate Hill, Archway, London N19 5LW, UK
    BMC Pulm Med 8:15. 2008
    ..We hypothesized that the ACE genotype might influence the severity of late respiratory complications of mustard gas exposure...
  2. ncbi request reprint Distal esophagitis in patients with mustard-gas induced chronic cough
    M Ghanei
    Research Center for Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Dis Esophagus 19:285-8. 2006
    ..In addition, they were suffering from asthma, chronic bronchitis and bronchiectasis. Bronchiolitis obliterans, along with other lung disorders, can be considered as contributors in the pathogenesis of esophagitis in MG exposed patients...
  3. ncbi request reprint Sinus CT scan findings in patients with chronic cough following sulfur mustard inhalation: a case-control study
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Tehran, Iran
    Inhal Toxicol 18:1135-8. 2006
    ..Consequently, current approaches to chronic cough just based on conventional etiologies in this setting can lead to delay in diagnosis and mismanagement...
  4. ncbi request reprint Mounier-Kuhn syndrome: a rare cause of severe bronchial dilatation with normal pulmonary function test: a case report
    Mostafa Ghanei
    Pulmonologist, Baqiyatallah University of Medical Sciences, Mollasadra Street, Tehran, Iran
    Respir Med 101:1836-9. 2007
    ..An underlying small airway disorders is responsible for abnormal reports in PFT of these patients. We may need to re-evaluate the role of PFT within follow-up of patients with large airway disorder...
  5. ncbi request reprint Clinical differentiation between resistant asthma and chronic bronchiolitis: testing a practical approach
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Research Center of Chemical Injuries, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:207-14. 2007
    ....
  6. doi request reprint An international collaborative pathologic study of surgical lung biopsies from mustard gas-exposed patients
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Mollasadra Street, PO Box 19945 546, Tehran, Iran
    Respir Med 102:825-30. 2008
    ..This study is the first to examine the histopathologic spectrum of changes in a large number of surgical lung biopsies from patients exposed to SM...
  7. doi request reprint Noninvasive diagnosis of bronchiolitis obliterans due to sulfur mustard exposure: could high-resolution computed tomography give us a clue?
    M Ghanei
    Chemical Injuries Research Center, Baqiyatallah University of Medical Science, Mollasadra Ave, 14359 16471, Tehran, Iran
    Radiol Med 115:413-20. 2010
    ..In this study, we investigated whether high-resolution computed tomography (HRCT) could be used as a noninvasive imaging modality to differentiate between mustard lung (as a subtype of BO) and other respiratory disorders...
  8. doi request reprint Overexpression of transforming growth factor (TGF)-beta1 and TGF-beta3 genes in lung of toxic-inhaled patients
    Aref Arzan Zarin
    Department of Genetics, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran
    Exp Lung Res 36:284-91. 2010
    ..These properties of TGF-beta are consistent with long-time survival of chemical-injured people suffering from BO...
  9. ncbi request reprint Therapeutics effect of N-acetyl cysteine on mustard gas exposed patients: evaluating clinical aspect in patients with impaired pulmonary function test
    Majid Shohrati
    Research Center of Chemical Injuries, Baqyatallah Medical Sciences University, Mollasadra Street, P O Box 19945 546, Tehran, Iran
    Respir Med 102:443-8. 2008
    ..The aim of this study was to determine the effect of 2- and 4-month administration of NAC (1800 mg daily) on mustard induced bronchiolitis obliterans...
  10. ncbi request reprint Long term consequences from exposure to sulfur mustard: a review
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Inhal Toxicol 19:451-6. 2007
    ..From this review we are able to provide a suitable practical plan for workup and management of patients in this setting...
  11. doi request reprint Evaluation of plasma, erythrocytes, and bronchoalveolar lavage fluid antioxidant defense system in sulfur mustard-injured patients
    Mahvash Jafari
    Department of Biochemistry, Chemical Injuries Research Center, Janbazan Medical and Engineering Research Center, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Clin Toxicol (Phila) 48:184-92. 2010
    ..This study was undertaken to evaluate the long-term effect of SM on plasma, erythrocytes, and brochoalveolar lavage fluid antioxidant defense system in SM-injured patients...
  12. doi request reprint Glutathione and malondialdehyde levels in late pulmonary complications of sulfur mustard intoxication
    Majid Shohrati
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Mollasadra Street, P O Box 19945 546, Tehran, Iran
    Lung 188:77-83. 2010
    ..These findings encourage us to examine therapeutic measures to correct such imbalances in future studies...
  13. doi request reprint Late respiratory effects of sulfur mustard: how is the early symptoms severity involved?
    M Ghanei
    Baqiyatallah Medical Sciences University, Chemical Injuries Research Center, Tehran, Islamic Republic of Iran
    Chron Respir Dis 5:95-100. 2008
    ..Bronchiolitis obliterans is the main underlying respiratory consequence of sulfur mustard exposures and may relate to host factors rather than to severity of early symptoms...
  14. doi request reprint N-acetylcysteine improves the clinical conditions of mustard gas-exposed patients with normal pulmonary function test
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Basic Clin Pharmacol Toxicol 103:428-32. 2008
    ..It also prevents sulfur mustard-induced oxidative stress, and can be used in the treatment of sulfur mustard-induced pulmonary disease...
  15. ncbi request reprint Furosemide inhalation in dyspnea of mustard gas-exposed patients: a triple-blind randomized study
    Yunes Panahi
    Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Tehran, Iran
    Inhal Toxicol 20:873-7. 2008
    ..In fact, we suggest that patients with a previous exposure to sulfur mustard, in which chronic bronchitis and bronchiolitis are the most suggested underlying mechanisms, may not benefit from furosemide to alleviate their dyspnea...
  16. ncbi request reprint Activity and function in lung injuries due to sulphur mustard
    Majid Shohrati
    Research Center of Chemical Injuries, Baqyiatallah Medical Sciences University, Mollasadra Street, Tehran, Iran
    Biomarkers 13:728-33. 2008
    ..Hence, the current study was performed to evaluate the correlation between superoxide dismutase (SOD) and catalase (CAT) activity and pulmonary function in patients exposed to sulphur mustard...
  17. ncbi request reprint Bronchiolitis obliterans following exposure to sulfur mustard: chest high resolution computed tomography
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, Chemical Warfare Victims Research Center, Mollasadra Street, Tehran, Iran
    Eur J Radiol 52:164-9. 2004
    ..We undertook this study to evaluate the chest high resolution computerized tomography (HRCT) as a diagnostic tool in patients with documented exposure to SM and chronic respiratory symptoms...
  18. ncbi request reprint Long-term respiratory disorders of claimers with subclinical exposure to chemical warfare agents
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, Research Center for Chemical Injuries, Tehran, Iran
    Inhal Toxicol 16:491-5. 2004
    ..There are many civilian and military people who have been present in contaminated area without signs and symptoms at the time of exposure, and early detection of such a population could be lifesaving...
  19. doi request reprint Long-term pulmonary complications of chemical warfare agent exposure in Iraqi Kurdish civilians
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Inhal Toxicol 22:719-24. 2010
    ..The high proportion of severe cases in comparison to reports from Iran may reflect the historical absence of effective early treatment, including strategies to reduce prolonged early exposure in this population...
  20. ncbi request reprint Tracheobronchomalacia and air trapping after mustard gas exposure
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Mollasadra Street, Tehran, 14359151371, Iran
    Am J Respir Crit Care Med 173:304-9. 2006
    ..Tracheobronchomalacia (TBM) and air trapping are often observed in high-resolution computerized tomography (HRCT) scans of the chest of mustard gas-exposed patients...
  21. doi request reprint Serum soluble Fas ligand and nitric oxide in long-term pulmonary complications induced by sulfur mustard: Sardasht-Iran Cohort Study
    Tooba Ghazanfari
    Immunoregulation Research Center, Shahed University, Tehran, Iran
    Int Immunopharmacol 9:1489-93. 2009
    ..Thus, our results indicate that elevated serum levels of sFasL may be associated with progression of pulmonary diseases in the SM exposed subjects...
  22. ncbi request reprint Correlation of sulfur mustard exposure and tobacco use with expression (immunoreactivity) of p53 protein in bronchial epithelium of Iranian "mustard lung" patients
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, Research Center of Chemical Injuries, Tehran, Iran
    Mil Med 172:70-4. 2007
    ..Initial data trends suggest an additive contribution of SM exposure and smoking to p53 immunoreactivity. These results illustrate the use of p53 immunoreactivity in the characterization of COPD, including mustard lung...
  23. ncbi request reprint Effect of gamma interferon on lung function of mustard gas exposed patients, after 15 years
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Tehran, Iran
    Pulm Pharmacol Ther 19:148-53. 2006
    ..The purpose of this research was to evaluate the efficacy of interferon gamma-1b on the lung function in MG exposed patients with bronchiolitis...
  24. ncbi request reprint Diagnostic and therapeutic value of short-term corticosteroid therapy in exacerbation of mustard gas-induced chronic bronchitis
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, Research Center of Chemical Injuries Tehran, Iran
    Basic Clin Pharmacol Toxicol 97:302-5. 2005
    ....
  25. ncbi request reprint Urogenital history in veterans exposed to high-dose sulfur mustard: a preliminary study of self-reported data
    Mohammad Reza Soroush
    Janbazan Medical and Engineering Research Center, Tehran, Iran
    Urol J 6:114-9; discussion 119. 2009
    ..We report the self-reported history of urologic conditions and findings on physical examination in a group of male veterans 19 to 26 years after exposed to high-dose sulfur mustard...
  26. ncbi request reprint Incidence of lung, eye, and skin lesions as late complications in 34,000 Iranians with wartime exposure to mustard agent
    Shahriar Khateri
    Chemical Warfare Victims Unit, Organization of Veterans Affairs, Tehran, Iran
    J Occup Environ Med 45:1136-43. 2003
    ....
  27. doi request reprint Late laryngeal findings in sulfur mustard poisoning
    Asghar Akhavan
    Baqiyatallah Medical Sciences University, Tehran, Islamic Republic of Iran
    Clin Toxicol (Phila) 47:142-4. 2009
    ..The purpose of the study was to describe abnormal laryngeal findings in a group of chemical war injury patients (soldiers) 20 years after an acute exposure to sulfur mustard...
  28. ncbi request reprint Assessment of fertility among mustard-exposed residents of Sardasht, Iran: a historical cohort study
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, BMSU Chemical Injuries Research Center, Mollasadra Street, P O Box 19945 546, Tehran, Iran
    Reprod Toxicol 18:635-9. 2004
    ..In the present study we hypothesize that infertility among mustard-exposed individuals is higher than among the general population...
  29. ncbi request reprint Inhaled corticosteroids and long-acting beta 2-agonists in treatment of patients with chronic bronchiolitis following exposure to sulfur mustard
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, Chemical Injury Research Center, Tehran, Iran
    Inhal Toxicol 19:889-94. 2007
    ..However, a medium dose of fluticasone/salmeterol has the same effect on the airways reversibility, rather than a very high dose of beclomethasone with only the short-acting beta-agonist...
  30. ncbi request reprint Tracheobronchial stenosis following sulfur mustard inhalation
    Mostafa Ghanei
    Baqiyatallah Medical Sciences University, Research Center of Chemical Injuries, Tehran, Iran
    Inhal Toxicol 16:845-9. 2004
    ....
  31. ncbi request reprint Delayed haematological complications of mustard gas
    Mostafa Ghanei
    Department of Internal Medicine, Baqiyatallah University of Medical Sciences, Chemical Injured Research Centre, Tehran, Iran
    J Appl Toxicol 24:493-5. 2004
    ..The mild increase in erythroid cells and haemoglobin concentration may be due to chronic obstructive pulmonary disorder and other respiratory diseases in these patients...
  32. doi request reprint Evaluation of activity and phenotype of alpha1-antitrypsin in a civil population with respiratory complications following exposure to sulfur mustard 20 years ago
    Majid Shohrati
    Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Tehran, Iran
    Biomarkers 15:47-51. 2010
    ..The reduced alpha1-antitrypsin (AAT) activities of some phenotypes have been suggested as contributing to the development of respiratory diseases...
  33. doi request reprint Lung carcinogenicity of sulfur mustard
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Clin Lung Cancer 11:13-7. 2010
    ..In summary, it is well documented that SM can cause human lung cancer after long-term exposure, but there has not been strong and definitive evidence for only short-term and acute, single, high-dose exposure until now...
  34. pmc An epidemiologic study to screen for chronic myelocytic leukemia in war victims exposed to mustard gas
    Mostafa Ghanei
    Chemical Warfare Victims Research Department, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Environ Health Perspect 110:519-21. 2002
    ..Because the increased development of CML in young patients with a documented history of exposure to mustard gas cannot be disregarded, further studies are needed...
  35. ncbi request reprint Cutaneous and ocular late complications of sulfur mustard in Iranian veterans
    Majid Shohrati
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Cutan Ocul Toxicol 26:73-81. 2007
    ..Also this agent is causes of chronic and delayed destructive lesions in the ocular surface and cornea, leading to progressive visual deterioration and ocular irritation...
  36. ncbi request reprint Immunobiological consequences of sulfur mustard contamination
    Zuhair Mohammad Hassan
    Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    Iran J Allergy Asthma Immunol 5:101-8. 2006
    ..The long term complications of these patients indicate the need to develop effective preventive and therapeutic strategies in the clinic. These strategies may be based upon immunopotentiating intervention and therapy...
  37. ncbi request reprint Delayed effects of sulfur mustard poisoning on CD4+ and CD8+ lymphocytes in Iranian veterans 25 years after exposure
    Hassan Mohammadhoseiniakbari
    Department of Pathology, School of Medical Science, University of Baqiyatallah, Tehran, Iran
    Med Sci Monit 14:CR580-3. 2008
    ....
  38. doi request reprint Effect of TGFß1 and TIMP2 on disease activity in asthma and COPD
    Mostafa Ghanei
    Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 9:79-86. 2010
    ..Furthermore TGFBeta1 may be served as a biomarker in sputum for assessing disease activity and evidence based prescribing corticosteroids in patients with COPD and asthma...
  39. ncbi request reprint Mustard lung secrets: long term clinicopathological study following mustard gas exposure
    Javad Beheshti
    Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
    Pathol Res Pract 202:739-44. 2006
    ..Two out of 14 cases showed changes suggestive of OP. Inhalation of SM can lead to persistant and clinically significant lung disease, including bronchial mucosal injury and OP, many years after exposure...
  40. ncbi request reprint Fibrogenic cytokine levels in bronchoalveolar lavage aspirates 15 years after exposure to sulfur mustard
    Reza Aghanouri
    Research Center for Chemical Injuries, Baqiyatallah University School of Medicine, IR Iran
    Am J Physiol Lung Cell Mol Physiol 287:L1160-4. 2004
    ..57). Inflammation and fibrotic processes in lung tissue of patients exposed to sulfur mustard may be progressive so IFN-gamma may be a useful drug to these patients' treatment...