Frank Zufall

Summary

Country: Germany

Publications

  1. ncbi request reprint TRPs in Olfaction
    Frank Zufall
    Department of Physiology and Center for Integrative Physiology and Molecular Medicine, University of Saarland School of Medicine, 66424, Homburg, Germany
    Handb Exp Pharmacol 223:917-33. 2014
  2. ncbi request reprint A wide range of pheromone-stimulated sexual and reproductive behaviors in female mice depend on G protein Gαo
    Livio Oboti
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    BMC Biol 12:31. 2014
  3. ncbi request reprint Link between pain and olfaction in an inherited sodium channelopathy
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrbergerstrasse 1, Bldg 58, D 66421 Homburg, Germany
    Arch Neurol 69:1119-23. 2012
  4. pmc Receptor guanylyl cyclases in mammalian olfactory function
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Gebäude 58, Kirrberger Str, 66421 Homburg, Germany
    Mol Cell Biochem 334:191-7. 2010
  5. ncbi request reprint A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany, Max Planck Research Unit for Neurogenetics, 60438 Frankfurt, Germany, and Department of Cell Biology and Center for Brain Integration Research, Tokyo Medical and Dental University, Graduate School of Medical and Dental Science, Bunkyo ku, Tokyo 113 8510, Japan
    J Neurosci 34:5121-33. 2014
  6. pmc Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
    Jan Weiss
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    Nature 472:186-90. 2011
  7. pmc G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, 66424 Homburg, Germany
    Proc Natl Acad Sci U S A 108:12898-903. 2011
  8. ncbi request reprint Grueneberg ganglion neurons are finely tuned cold sensors
    Andreas Schmid
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    J Neurosci 30:7563-8. 2010
  9. pmc Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties
    Bernd Bufe
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    J Biol Chem 287:33644-55. 2012
  10. doi request reprint The electrovomeronasogram: field potential recordings in the mouse vomeronasal organ
    Trese Leinders-Zufall
    Department of Physiology, School of Medicine, University of Saarland, Homburg, Germany
    Methods Mol Biol 1068:221-36. 2013

Collaborators

Detail Information

Publications14

  1. ncbi request reprint TRPs in Olfaction
    Frank Zufall
    Department of Physiology and Center for Integrative Physiology and Molecular Medicine, University of Saarland School of Medicine, 66424, Homburg, Germany
    Handb Exp Pharmacol 223:917-33. 2014
    ..Here, I review such findings and discuss future areas for investigation. ..
  2. ncbi request reprint A wide range of pheromone-stimulated sexual and reproductive behaviors in female mice depend on G protein Gαo
    Livio Oboti
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    BMC Biol 12:31. 2014
    ....
  3. ncbi request reprint Link between pain and olfaction in an inherited sodium channelopathy
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrbergerstrasse 1, Bldg 58, D 66421 Homburg, Germany
    Arch Neurol 69:1119-23. 2012
    ..This advance offers a functional understanding of a monogenic human disorder that is characterized by a loss of 2 major senses-nociception and smell-thus providing an unexpected mechanistic link between these 2 sensory modalities...
  4. pmc Receptor guanylyl cyclases in mammalian olfactory function
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Gebäude 58, Kirrberger Str, 66421 Homburg, Germany
    Mol Cell Biochem 334:191-7. 2010
    ..In this review, we discuss key findings that have reinvigorated the study of guanylyl cyclase function in the olfactory system...
  5. ncbi request reprint A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany, Max Planck Research Unit for Neurogenetics, 60438 Frankfurt, Germany, and Department of Cell Biology and Center for Brain Integration Research, Tokyo Medical and Dental University, Graduate School of Medical and Dental Science, Bunkyo ku, Tokyo 113 8510, Japan
    J Neurosci 34:5121-33. 2014
    ..Thus, H2-Mv genes are not absolutely essential for the generation of physiological responses, but are required for ultrasensitive chemodetection by a subset of VSNs. ..
  6. pmc Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
    Jan Weiss
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    Nature 472:186-90. 2011
    ..Our study creates a mouse model of congenital general anosmia and provides new strategies to explore the genetic basis of the human sense of smell...
  7. pmc G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, 66424 Homburg, Germany
    Proc Natl Acad Sci U S A 108:12898-903. 2011
    ..These cellular and behavioral phenotypes identify Gαo as the primary G-protein α-subunit mediating the detection of peptide and protein pheromones by sensory neurons of the VNO...
  8. ncbi request reprint Grueneberg ganglion neurons are finely tuned cold sensors
    Andreas Schmid
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    J Neurosci 30:7563-8. 2010
    ..These findings establish the Grueneberg ganglion as a sensory organ mediating cold-evoked neural responses, possibly in conjunction with the sensing of other stress- or fear-related chemical social cues...
  9. pmc Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties
    Bernd Bufe
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    J Biol Chem 287:33644-55. 2012
    ..The same peptide motifs are contained in pathogenic microorganisms. Thus, the ligand profile of mFpr-rs1 is consistent with a role in vomeronasal pathogen sensing...
  10. doi request reprint The electrovomeronasogram: field potential recordings in the mouse vomeronasal organ
    Trese Leinders-Zufall
    Department of Physiology, School of Medicine, University of Saarland, Homburg, Germany
    Methods Mol Biol 1068:221-36. 2013
    ....
  11. doi request reprint From genes to social communication: molecular sensing by the vomeronasal organ
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, D 66424 Homburg, Germany
    Trends Neurosci 35:597-606. 2012
    ....
  12. doi request reprint Structural requirements for the activation of vomeronasal sensory neurons by MHC peptides
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    Nat Neurosci 12:1551-8. 2009
    ..We suggest that the peptide presentation system provided by MHC molecules co-evolves with the peptide recognition systems expressed by T cells and VSNs...
  13. pmc Contribution of the receptor guanylyl cyclase GC-D to chemosensory function in the olfactory epithelium
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg Saar, Germany
    Proc Natl Acad Sci U S A 104:14507-12. 2007
    ....
  14. ncbi request reprint Mammalian pheromone sensing
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrberger Strasse, 66421 Homburg Saar, Germany
    Curr Opin Neurobiol 17:483-9. 2007
    ..Selective genetic targeting of these subsystems should help to unravel their biological role in pheromone-mediated behavioral responses...