Frank Zufall

Summary

Country: Germany

Publications

  1. ncbi Link between pain and olfaction in an inherited sodium channelopathy
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrbergerstrasse 1, Bldg 58, D 66421 Homburg, Germany
    Arch Neurol 69:1119-23. 2012
  2. ncbi Receptor guanylyl cyclases in mammalian olfactory function
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Gebäude 58, Kirrberger Str, 66421 Homburg, Germany
    Mol Cell Biochem 334:191-7. 2010
  3. ncbi Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
    Jan Weiss
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    Nature 472:186-90. 2011
  4. ncbi Grueneberg ganglion neurons are finely tuned cold sensors
    Andreas Schmid
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    J Neurosci 30:7563-8. 2010
  5. ncbi Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties
    Bernd Bufe
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    J Biol Chem 287:33644-55. 2012
  6. ncbi G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, 66424 Homburg, Germany
    Proc Natl Acad Sci U S A 108:12898-903. 2011
  7. ncbi From genes to social communication: molecular sensing by the vomeronasal organ
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, D 66424 Homburg, Germany
    Trends Neurosci 35:597-606. 2012
  8. ncbi Structural requirements for the activation of vomeronasal sensory neurons by MHC peptides
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    Nat Neurosci 12:1551-8. 2009
  9. ncbi Contribution of the receptor guanylyl cyclase GC-D to chemosensory function in the olfactory epithelium
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg Saar, Germany
    Proc Natl Acad Sci U S A 104:14507-12. 2007
  10. ncbi Mammalian pheromone sensing
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrberger Strasse, 66421 Homburg Saar, Germany
    Curr Opin Neurobiol 17:483-9. 2007

Collaborators

Detail Information

Publications10

  1. ncbi Link between pain and olfaction in an inherited sodium channelopathy
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrbergerstrasse 1, Bldg 58, D 66421 Homburg, Germany
    Arch Neurol 69:1119-23. 2012
    ..This advance offers a functional understanding of a monogenic human disorder that is characterized by a loss of 2 major senses-nociception and smell-thus providing an unexpected mechanistic link between these 2 sensory modalities...
  2. ncbi Receptor guanylyl cyclases in mammalian olfactory function
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Gebäude 58, Kirrberger Str, 66421 Homburg, Germany
    Mol Cell Biochem 334:191-7. 2010
    ..In this review, we discuss key findings that have reinvigorated the study of guanylyl cyclase function in the olfactory system...
  3. ncbi Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
    Jan Weiss
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    Nature 472:186-90. 2011
    ..Our study creates a mouse model of congenital general anosmia and provides new strategies to explore the genetic basis of the human sense of smell...
  4. ncbi Grueneberg ganglion neurons are finely tuned cold sensors
    Andreas Schmid
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    J Neurosci 30:7563-8. 2010
    ..These findings establish the Grueneberg ganglion as a sensory organ mediating cold-evoked neural responses, possibly in conjunction with the sensing of other stress- or fear-related chemical social cues...
  5. ncbi Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties
    Bernd Bufe
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg, Germany
    J Biol Chem 287:33644-55. 2012
    ..The same peptide motifs are contained in pathogenic microorganisms. Thus, the ligand profile of mFpr-rs1 is consistent with a role in vomeronasal pathogen sensing...
  6. ncbi G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, 66424 Homburg, Germany
    Proc Natl Acad Sci U S A 108:12898-903. 2011
    ..These cellular and behavioral phenotypes identify Gαo as the primary G-protein α-subunit mediating the detection of peptide and protein pheromones by sensory neurons of the VNO...
  7. ncbi From genes to social communication: molecular sensing by the vomeronasal organ
    Pablo Chamero
    Department of Physiology, University of Saarland School of Medicine, D 66424 Homburg, Germany
    Trends Neurosci 35:597-606. 2012
    ....
  8. ncbi Structural requirements for the activation of vomeronasal sensory neurons by MHC peptides
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, Homburg, Germany
    Nat Neurosci 12:1551-8. 2009
    ..We suggest that the peptide presentation system provided by MHC molecules co-evolves with the peptide recognition systems expressed by T cells and VSNs...
  9. ncbi Contribution of the receptor guanylyl cyclase GC-D to chemosensory function in the olfactory epithelium
    Trese Leinders-Zufall
    Department of Physiology, University of Saarland School of Medicine, 66421 Homburg Saar, Germany
    Proc Natl Acad Sci U S A 104:14507-12. 2007
    ....
  10. ncbi Mammalian pheromone sensing
    Frank Zufall
    Department of Physiology, University of Saarland School of Medicine, Kirrberger Strasse, 66421 Homburg Saar, Germany
    Curr Opin Neurobiol 17:483-9. 2007
    ..Selective genetic targeting of these subsystems should help to unravel their biological role in pheromone-mediated behavioral responses...