Research Topics
| A ZettlSummaryCountry: Germany Publications
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Detail Information
Publications
Genomic profiling of peripheral T-cell lymphoma, unspecified, and anaplastic large T-cell lymphoma delineates novel recurrent chromosomal alterationsAndreas Zettl
Department of Pathology, University of Wurzburg, Wurzburg, Germany
Am J Pathol 164:1837-48. 2004..The genetics of PTCL NOS and ALK-negative ALCL differ from other T-NHLs characterized genetically so far, among them enteropathy-type T-cell lymphoma, T-cell prolymphocytic leukemia, and adult T-cell lymphoma/leukemia...
Chromosomal gains at 9q characterize enteropathy-type T-cell lymphomaAndreas Zettl
Department of Pathology, University of Wurzburg, Germany
Am J Pathol 161:1635-45. 2002....
[Enteropathy type T-cell lymphomas: pathology and pathogenesis]A Zettl
Institut fur Pathologie, Julius Maximilians Universitat Wurzburg
Pathologe 28:59-64. 2007..Genetically, ETL is characterized by frequent and recurrent chromosomal gains of 9q33-q34...
Composite marginal zone B-cell lymphoma and classical Hodgkin's lymphoma: a clinicopathological study of 12 casesA Zettl
Institute of Pathology, University of Wurzburg, Wurzburg, Germany
Histopathology 46:217-28. 2005..We characterized 12 cases of composite marginal zone B-cell lymphoma (MZBL) and cHL by immunohistochemistry and molecular biology...
Tissue microarray-based screening for chromosomal breakpoints affecting the T-cell receptor gene loci in mature T-cell lymphomasE Leich
Institute of Pathology, University of Wurzburg, Germany
J Pathol 213:99-105. 2007....
Pathology of lymphoma progressionH K Muller-Hermelink
Institute of Pathology, University of Wurzburg, Wurzburg, Germany
Histopathology 38:285-306. 2001..Within different lymphoma entities, high-risk disease variants mimicking lymphoma progression exist...
[Peripheral NK/T-cell lymphoma]T Rudiger
Institut fur Pathologie, Universitat Wurzburg
Pathologe 28:55-8. 2007..In addition, there is a clonal infection by Epstein-Barr virus in the T-lymphocytes. In the differential diagnosis, B-cell lymphomas are more frequent at all localizations than T- or NK-cell lymphomas...
Genetic aberrations common in gastric high-grade large B-cell lymphomaP Starostik
Institute of Pathology and Division of Medicine, Wuerzburg University, Wuerzburg, Germany
Blood 95:1180-7. 2000..Common genetic aberrations responsible for lymphomagenesis are deletions of 6q, loss of p53, and amplification of the 3q27 and the MLL gene regions. (Blood. 2000;95:1180-1187)..
What is CD4+CD56+ malignancy and how should it be treated?P Reimer
Medizinische Poliklinik, Universitaet Wuerzburg, Wuerzburg, Germany
Bone Marrow Transplant 32:637-46. 2003..This therapeutic approach should be recommended for eligible patients with CD4+CD56+ malignancy. For older patients the best treatment option is still unknown...
[Myelosarcoma of the proximal jejunum. A rare primary condition of acute myelogenous leukemia]H Tigges
Chirurgische Klinik der Universität Würzburg, Germany
Chirurg 73:1127-31. 2002..We present a 40 year old man with myelosarcoma of the jejunum and discuss this entity and its therapeutic options...
Immunohistochemical analysis of B-cell lymphoma using tissue microarrays identifies particular phenotypic profiles of B-cell lymphomasA Zettl
Institute of Pathology, , , Germany
Histopathology 43:209-19. 2003..MCL and DLBL frequently showed aberrant p27KIP1 expression. A p53 + p21- immunophenotype in >20% of tumour cells in B-cell non-Hodgkin's lymphoma correlates with p53 gene deletion...
Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphomaS Nagel
Department of Human and Animal Cell Cultures, DSMZ, Braunschweig, Germany
Leukemia 22:387-92. 2008..Taken together, analysis of the 7q22 amplicon identified CDK6 as an important cell cycle regulator in T-cell lymphomas, representing a novel potential target for rational therapy...
[Anaplastic large cell lymphomas lack the expression of T-cell receptor molecules]T Rudiger
Pathologisches Institut der Universitat Wurzburg
Verh Dtsch Ges Pathol 89:261-6. 2005..This molecular hallmark of ALCL is analogous to defective immunoglobulin expression distinguishing Hodgkin lymphoma from other B-cell lymphomas...
True malignant mixed tumour (carcinosarcoma) of submandibular gland--a rare neoplasm of monoclonal origin?H U Volker
Histopathology 50:795-8. 2007
Thymic epithelial tumors can develop along two different pathogenetic pathwaysR Zhou
Institute of Pathology and Forensic Medicine, Zhejiang University Medical School, Zhejiang, China
Am J Pathol 159:1853-60. 2001..2 and 8q11.21-23. The absence of these aberrations might be the reason for the well-known benign behavior of type A thymomas as compared to types B3 and C tumors...
