Research Topics
| Hans Ulrich WittchenSummaryCountry: Germany Publications
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Publications
Generalized anxiety and depression in primary care: prevalence, recognition, and managementHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
J Clin Psychiatry 63:24-34. 2002....
Natural course and burden of bipolar disordersHans Ulrich Wittchen
Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy D 01062 Dresden, Germany
Int J Neuropsychopharmacol 6:145-54. 2003..iii) The value of both types of studies might be enhanced, if beyond the use of standardized diagnostic interview, special attempts are made to use prospective life- and episode-charting methods for bipolar illnesses...
Depressive episodes--evidence for a causal role of primary anxiety disorders?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Dresden University of Technology, Chemnitzerstrasse 46, 01187 Dresden, Germany
Eur Psychiatry 18:384-93. 2003..The goal of this paper is to review recent literature, summarize implications of previous findings, and suggest directions for future research regarding preventive and intervention strategies...
Size and burden of mental disorders in Europe--a critical review and appraisal of 27 studiesHans Ulrich Wittchen
Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Eur Neuropsychopharmacol 15:357-76. 2005..These needs are most pronounced for the new EU member states as well as more generally for adolescent and older populations...
Generalized anxiety disorder: prevalence, burden, and cost to societyHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
Depress Anxiety 16:162-71. 2002....
Frequency of dementia, depression, and other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's diseaseOliver Riedel
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
J Neurol 257:1073-82. 2010..PD outpatients are at an increased risk for all neuropsychiatric conditions, increasing with PD severity but not with age or age of onset (except dementia), revealing challenging symptom patterns...
The relevance of age at first alcohol and nicotine use for initiation of cannabis use and progression to cannabis use disordersSilke Behrendt
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, D 01187 Dresden, Germany
Drug Alcohol Depend 123:48-56. 2012..However, the cross-substance relationship between a younger age at onset of alcohol use (AU) and nicotine use (NU) and the risk of cannabis use disorders (CUD) in adolescence and early adulthood remains unclear...
Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of lifeKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Arch Gen Psychiatry 64:903-12. 2007....
The structure of mental disorders re-examined: is it developmentally stable and robust against additions?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Int J Methods Psychiatr Res 18:189-203. 2009..However, again, there is little consistency in findings when different age groups or different diagnoses are considered. Our findings suggest that psychopathology cannot be reduced to any simple structure...
Incidence and risk patterns of anxiety and depressive disorders and categorization of generalized anxiety disorderKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer St 46, 01187 Dresden, Germany
Arch Gen Psychiatry 67:47-57. 2010..Controversy surrounds the diagnostic categorization of generalized anxiety disorder (GAD)...
Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination SurveyFrank Jacobi
Institute of Clinical Psychology and Psychotherapy, Unit, Technical University of Dresden, Germany
Int J Methods Psychiatr Res 11:1-18. 2002..Overall, the GHS core survey and its mental health supplement provide the mental health research community with complex data that allow for high-quality analysis of mental disorders and associations with somatic disorders...
Pain associated with specific anxiety and depressive disorders in a nationally representative population sampleKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187, Dresden, Germany
Soc Psychiatry Psychiatr Epidemiol 45:89-104. 2010....
Occurrence risk and structure of depression in Parkinson disease with and without dementia: results from the GEPAD StudyOliver Riedel
Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
J Geriatr Psychiatry Neurol 23:27-34. 2010....
The structure of common mental disorders: a replication study in a community sample of adolescents and young adultsKatja Beesdo-Baum
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Int J Methods Psychiatr Res 18:204-20. 2009....
Depression does not affect the treatment outcome of CBT for panic and agoraphobia: results from a multicenter randomized trialAngela Emmrich
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Psychother Psychosom 81:161-72. 2012....
The diagnostic threshold of generalized anxiety disorder in the community: a developmental perspectiveKatja Beesdo-Baum
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Street 46, 01187 Dresden, Germany
J Psychiatr Res 45:962-72. 2011..Developmental aspects require stronger consideration in future diagnostic systems...
Agoraphobia and panic. Prospective-longitudinal relations suggest a rethinking of diagnostic conceptsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Psychother Psychosom 77:147-57. 2008..The aim of the current study is to prospectively examine the 10-year natural course of PA, PD and AG in the first three decades of life, their stability and their reciprocal transitions...
Social fear and social phobia types among community youth: differential clinical features and vulnerability factorsSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
J Psychiatr Res 45:111-20. 2011....
Prevalence, incidence and determinants of PTSD and other mental disorders: design and methods of the PID-PTSD+3 studyHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Int J Methods Psychiatr Res 21:98-116. 2012..We expect the findings to advance our understanding of a wide spectrum of adverse mental health outcomes beyond PTSD...
Frequency of albuminuria in primary care: a cross-sectional studyPeter Bramlage
Institute for Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
Eur J Cardiovasc Prev Rehabil 14:107-13. 2007....
Trajectory classes of decline in health-related quality of life in Parkinson's disease: a pilot studyJens Klotsche
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Value Health 14:329-38. 2011..To analyze the change in health-related quality-of-life (HRQoL) in patients with Parkinson's disease (PD) and to identify different classes of HRQoL decline...
Characterizing the association between parenting and adolescent social phobiaSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
J Anxiety Disord 26:608-16. 2012..paternal contributions, putative predictors of unfavorable parenting behaviors and its specificity for SP are warranted to delineate targeted prevention and intervention strategies...
The natural course of cannabis use, abuse and dependence during the first decades of lifeAxel Perkonigg
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
Addiction 103:439-49; discussion 450-1. 2008..The current study estimated rates and risk factors associated with stability and variation in cannabis use patterns, cannabis abuse and cannabis dependence in a community sample over a 10-year period...
Estimating causal effects from observational data with a model for multiple biasMichael Hofler
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46a, 01187 Dresden, Germany
Int J Methods Psychiatr Res 16:77-87. 2007..Multiple bias modelling, if properly used, reveals the necessity for a better understanding of bias, suggesting a need to conduct larger and more adequate validation studies on instruments that are used to diagnose mental disorders...
Psychometric properties of the Retrospective Self Report of Inhibition (RSRI) in a representative German sampleHeike Rohrbacher
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, Germany
Int J Methods Psychiatr Res 17:80-8. 2008..The psychometric properties of the German RSRI were found to be comparable to those of the English version. The applicability of this questionnaire in German-speaking countries is therefore recommended for adolescents and young adults...
(Don't) panic in the scanner! How panic patients with agoraphobia experience a functional magnetic resonance imaging sessionUlrike Lueken
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
Eur Neuropsychopharmacol 21:516-25. 2011..Future studies are needed to investigate the relationship between self-reported distress and fMRI data in patient groups that are subject to neuroimaging research...
Psychometric properties of the dimensional anxiety scales for DSM-V in an unselected sample of German treatment seeking patientsKatja Beesdo-Baum
Institute of Clinical Psychology and Psychotherapy, Tech nische Universitaet Dresden, Germany
Depress Anxiety 29:1014-24. 2012..These scales use a common template to assess core constructs of fear and anxiety...
Association chain graphs: modelling etiological pathwaysMichael Hofler
Technical University Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
Int J Methods Psychiatr Res 12:77-84. 2003..With this new type of graph, more specific information can be displayed whenever the data are essentially described only with statistical main- and two-way interaction effects...
The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: results from three clinical trialsKatja Beesdo
Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
J Anxiety Disord 23:1064-71. 2009..02). In conclusion, duloxetine was efficacious in the short- and long-term treatment of PPS, which are common in GAD patients...
Anxiety disorders before birth and self-perceived distress during pregnancy: associations with maternal depression and obstetric, neonatal and early childhood outcomesJulia Martini
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet, Dresden, Germany
Early Hum Dev 86:305-10. 2010..However, studies considering the effect of DSM-IV anxiety disorders beyond maternal self-perceived distress during pregnancy and its timing are lacking...
Binary regression: Total gain in positive and negative predictive valuesJens Klotsche
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Straße 46, 01187, Dresden, Germany Center of Clinical Epidemiology and Longitudinal Studies CELOS, Technische Universitaet Dresden, Chemnitzer Straße 46, 01187, Dresden, Germany
Biom J 54:808-23. 2012..Both measures provide a useful tool for assessing the performance or accuracy of a set of predictor variables for the prediction of a binary outcome. This concept is a tool for evaluating the optimal prediction model in future research...
Posttraumatic stress disorder: diagnostic and epidemiological perspectivesHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
CNS Spectr 14:5-12. 2009..A further exploitation of the existing data, and an improvement of existing epidemiological methods, strategies, and assessments are likely to substantially contribute to the clarification of unresolved diagnostic issues...
How specific is specific phobia? Different neural response patterns in two subtypes of specific phobiaUlrike Lueken
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, 01187 Dresden, Germany
Neuroimage 56:363-72. 2011..If replicated, results could contribute to a better understanding of underlying neurobiological mechanisms of specific phobia and their respective classification...
Within and between session changes in subjective and neuroendocrine stress parameters during magnetic resonance imaging: A controlled scanner training studyUlrike Lueken
Department of Psychology, Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Psychoneuroendocrinology 37:1299-308. 2012..If replicated, present findings should be considered by researchers employing repeated measurement designs where subjects are exposed to a scanner more than once...
A novel nonparametric approach for estimating cut-offs in continuous risk indicators with application to diabetes epidemiologyJens Klotsche
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
BMC Med Res Methodol 9:63. 2009..The cut-off corresponding to the Youden-Index is often applied in epidemiology and biomedical literature for dichotomizing a continuous risk indicator...
Feasibility and outcome of substitution treatment of heroin-dependent patients in specialized substitution centers and primary care facilities in Germany: a naturalistic study in 2694 patientsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzerstrasse 46, 01187 Dresden, Germany
Drug Alcohol Depend 95:245-57. 2008..Despite many short-term studies, little is known about the long-term (12-month) effects of these treatments in different settings, i.e. primary care-based (PMC) and specialized substitution centers (SSCs)...
Symptom provocation in dental anxiety using cross-phobic video stimulationUlrike Lueken
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Eur J Oral Sci 119:61-8. 2011..The validation of the paradigm may support and stimulate future research on the characterization of dental anxiety on different response systems, including its underlying neural substrates...
Agoraphobia: a review of the diagnostic classificatory position and criteriaHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, D 01187Dresden, Germany
Depress Anxiety 27:113-33. 2010....
Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD)Oliver Riedel
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
J Neurol 255:255-64. 2008..Prevalence estimates of these complications are quite variable and are lacking for the outpatient care sector...
Re-examining the differential familial liability of agoraphobia and panic disorderSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Tech nische Universitaet, Dresden, Germany
Depress Anxiety 29:931-8. 2012..Convincing evidence for either position notably requires considering also other anxiety disorders to establish the position of AG relative to the panic/anxiety spectrum...
Abstinence orientation and treatment practice: an analysis of German settings providing opioid maintenance therapySebastian Trautmann
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Subst Use Misuse 47:22-30. 2012..Patients in HAOs were more likely to undergo psychotherapeutic and psychiatric treatment than in MAOs and LAOs. Limitations, conclusions, and future research are suggested...
Risk and speed of transitions to first alcohol dependence symptoms in adolescents: a 10-year longitudinal community study in GermanySilke Behrendt
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Addiction 103:1638-47. 2008..It is unclear whether early onset of AU is associated with the speed of transition to first AD symptoms and whether specific first AD symptoms and their timing are associated with AD...
Smoking cessation in primary care - a randomized controlled trial of bupropione, nicotine replacements, CBT and a minimal interventionHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Int J Methods Psychiatr Res 20:28-39. 2011..Smoking cessation has been shown to be effective in randomized controlled trials. It is unclear though, whether interventions also work in routine primary care...
Accuracy of anthropometric indicators of obesity to predict cardiovascular riskHarald J Schneider
Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden, Germany
J Clin Endocrinol Metab 92:589-94. 2007..However, more recently, waist to hip ratio (WHR) or waist circumference (WC) as more sensitive measures for visceral obesity have been proposed to be more indicative of cardiovascular risk...
Women-specific mental disorders in DSM-V: are we failing again?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
Arch Womens Ment Health 13:51-5. 2010....
Posttraumatic stress disorder and obesity: evidence for a risk associationAxel Perkonigg
Department of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Am J Prev Med 36:1-8. 2009..The aim of this study was to examine prospective longitudinal associations between PTSD and obesity in a community sample...
Familial risk factors in social anxiety disorder: calling for a family-oriented approach for targeted prevention and early interventionSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
Eur Child Adolesc Psychiatry 19:857-71. 2010..This review sets out to develop a more family-oriented approach for predicting the onset and maintenance of SAD that may be fruitful to derive targeted prevention and early intervention in SAD...
Effectiveness of day hospital treatment for anorexia nervosa and bulimia nervosaEike Fittig
Unit for Eating Disorders Research, Institute of Clinical Psychology, Technical University of Dresden, Germany
Eur Eat Disord Rev 16:341-51. 2008..The results demonstrate both the short-term effectiveness and long-term stability of day hospital treatment in a large sample of patients with anorexia and BN...
Common and distinct amygdala-function perturbations in depressed vs anxious adolescentsKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Strasse 46, Dresden, Germany
Arch Gen Psychiatry 66:275-85. 2009..Few studies directly compare amygdala function in depressive and anxiety disorders. Data from longitudinal research emphasize the need for such studies in adolescents...
DSM-IV pain disorder in the general population. An exploration of the structure and threshold of medically unexplained pain symptomsChristine Frohlich
Technische Universitat Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
Eur Arch Psychiatry Clin Neurosci 256:187-96. 2006..Despite an abundance of questionnaire data, the prevalence of clinically significant and medically unexplained pain syndromes in the general population has rarely been examined with a rigid personal-interview methodology...
The position of anxiety disorders in structural models of mental disordersHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universita t Dresden, Chemnitzer Strasse 46, D 01187 Dresden, Germany
Psychiatr Clin North Am 32:465-81. 2009..Extant results are not stable enough to form the basis of clinical diagnostic classification systems such as DSM and the International Classification of Diseases...
Association between generalized anxiety levels and pain in a community sample: evidence for diagnostic specificityKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
J Anxiety Disord 23:684-93. 2009..It is unclear whether generalized anxiety disorder (GAD) has a specific relationship to pain syndromes, going beyond the established association of pain with anxiety syndromes in general...
Developments in the treatment and diagnosis of anxiety disordersHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Strasse 46, D 01187 Dresden, Germany
Psychiatr Clin North Am 32:xiii-xix. 2009..This article reviews these critical issues and sets the stage for the other articles in this special issue...
Do parental psychopathology and unfavorable family environment predict the persistence of social phobia?Susanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
J Anxiety Disord 23:986-94. 2009..Predictors for SP persistence differ from those predicting SP onset. Unfavorable family environment alone and in interaction with parental disorders predict higher SP persistence...
Prevalence of generalized anxiety disorder in general practice in Denmark, Finland, Norway, and SwedenPovl Munk-Jørgensen
Unit for Psychiatric Research, Aalborg Psychiatric Hospital, Aarhus University Hospital, Mølleparkvej 10, Aalborg, Denmark DK 9000
Psychiatr Serv 57:1738-44. 2006..This study assessed the prevalence rate of generalized anxiety disorder among patients of general practitioners in Denmark, Finland, Norway, and Sweden and determined whether general practitioners recognize the condition and its correlates...
Human and economic burden of generalized anxiety disorderDeborah L Hoffman
Independent Outcomes Research Consultant, New Haven, CT, USA
Depress Anxiety 25:72-90. 2008..Quality of care initiatives that have been implemented to increase recognition and improve treatment outcomes for persons with MDD should be extended to the effective management of GAD...
Prevalence and burden of bipolar disorders in European countriesStefano Pini
Department of Psychiatry, University of Pisa, Via Roma, 67 56100, Pisa, Italy
Eur Neuropsychopharmacol 15:425-34. 2005..Most studies suggest equally high or even higher levels of impairments and disabilities of bipolar disorders as compared to major depression and schizophrenia. Few data are available on treatment and health care utilization...
Patterns and correlates of generalized anxiety disorder in community samplesRonald C Kessler
Department of Health Care Policy, Harvard Medical School, Boston, Mass 02115, USA
J Clin Psychiatry 63:4-10. 2002..Although generalized anxiety disorder (GAD) is at least twice as prevalent as panic disorder and is among the commonly occurring mental disorders, changing diagnostic criteria have hampered the cumulation of data on patterns and correlates...
Panic attack as a risk factor for severe psychopathologyRenee D Goodwin
Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804 Munich, Germany
Am J Psychiatry 161:2207-14. 2004..Investigation of key family, environmental, and individual factors associated with the onset of panic attacks, especially in youth, may be an important direction for future research...
Prevalence of psychiatric disorders in an onset cohort of adults with type 1 diabetesFrank Petrak
Department for Psychosomatic Medicine and Psychotherapy, Johannes Gutenberg University Mainz, Untere Zahlbacherstrasse 8, D 55131 Mainz, Germany
Diabetes Metab Res Rev 19:216-22. 2003..The aim of our study was to determine if newly diagnosed adults with type 1 diabetes already have an elevated rate of psychiatric disorders at the beginning of their physical illness...
Anxiety disorders in mothers and their children: prospective longitudinal community studyAndrea Schreier
Max Planck Institute of Psychiatry, Munich, Germany
Br J Psychiatry 192:308-9. 2008..These results suggest that the type of maternal anxiety disorder and its severity of manifestation contribute to mother-offspring aggregation of anxiety...
Long-term efficacy of pregabalin in generalized anxiety disorderDouglas Feltner
Pfizer Global Research and Development, Ann Arbor, Missouri, USA
Int Clin Psychopharmacol 23:18-28. 2008..2%), headache (10.1 vs. 11.2%), and somnolence (6.0 vs. 0%). No safety concerns were identified with long-term treatment. The study indicates that pregabalin is an effective treatment for the prevention of relapse in patients with GAD...
Risk factors for depression at 12-month follow-up in adult primary health care patients with major depression: an international prospective studyKatrin Barkow
Department of Psychiatry, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
J Affect Disord 76:157-69. 2003..The findings from the WHO Collaborative Study on 'Psychological Problems in General Health Care' might be generalised to different cultural environments...
Aims, design and methods of the Smoking and Nicotine Dependence Awareness and Screening (SNICAS) studyStephan Muehlig
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Int J Methods Psychiatr Res 12:208-28. 2003..This paper provides an overview of the design and methods of the study, informs about sampling and response rates, and examines whether the study sample could be considered representative of German primary care doctors...
Mixed anxiety-depression in a 1 year follow-up study: shift to other diagnoses or remission?Katrin Barkow
Department of Psychiatry, University of Bonn, Germany
J Affect Disord 79:235-9. 2004..However, a study examining the stability of this ICD-10-diagnosis is lacking. Our objective was to examine the 12 month outcome of MAD in comparison to the outcome of depression, anxiety, and comorbid depression and anxiety...
High prevalence and poor control of hypertension in primary care: cross-sectional studyArya M Sharma
Franz Volhard Clinic Charité, Berlin, Germany
J Hypertens 22:479-86. 2004....
What characteristics of primary anxiety disorders predict subsequent major depressive disorder?Antje Bittner
Department of Clinical Psychology and Psychotherapy, Technical University Dresden, Dresden, Germany
J Clin Psychiatry 65:618-26, quiz 730. 2004....
HYDRA: possible determinants of unsatisfactory hypertension control in German primary care patientsU Muscha Steckelings
Center for Cardiovascular Research Institute of Pharmacology and Toxicology, Charite, Berlin, Germany
Blood Press 13:80-8. 2004..These insights into the causes of unsatisfactory hypertension control may help to direct future educational programmes designed to improve hypertension management specifically to these deficits and thereby to improve control rates...
Continued needs for epidemiological studies of mental disorders in the communityHans-Ulrich Wittchen
Psychother Psychosom 73:197-206. 2004
[The use of guidelines in the primary care management of hypertension and diabetes]Nicole Wagner
Institut für Klinische Pharmakologie und Forschungsverbund Public Health Sachsen und Sachsen Anhalt e V, TU Dresden
Soz Praventivmed 49:261-8. 2004..The paper examines to what degree German primary care physicians know and work along the rules established in guidelines for arterial hypertension and diabetes mellitus...
Smoking increases the risk of panic: findings from a prospective community studyBarbara Isensee
Clinical Psychology and Epidemiology Unit, Max-Planck-Institute of Psychiatry, Munich, Germany
Arch Gen Psychiatry 60:692-700. 2003..However, we could not exclude the existence of a second, less frequent, reverse pathway of prior panic and secondary nicotine dependence...
Maternal smoking and smoking in adolescents: a prospective community study of adolescents and their mothersRoselind Lieb
Clinical Psychology and Epidemiology Unit, Max Planck Institute of Psychiatry, Munich, Germany
Eur Addict Res 9:120-30. 2003..Our findings show that maternal smoking predicts escalation of smoking, development of nicotine dependence, and stability of smoking behavior in children. Implications for specific intervention and prevention efforts are discussed...
Test-retest reliability of self-reported age at onset of selected psychiatric diagnoses in general health careKatrin Barkow
Department of Psychiatry, University of Bonn, Germany
Acta Psychiatr Scand 106:117-25. 2002..CONCLUSION: Self-reported age at onset is reliable. Further research on factors associated with reliability should focus on interview conditions and subject parameters during interview...
Life events and changes in the course of depression in young adultsRobert H Friis
Department of Health Science, California State University, Long Beach, CA, USA
Eur Psychiatry 17:241-53. 2002..CONCLUSIONS: The association between life events and the course of depression appears to vary according to the outcome being examined, with different clusters of life events differentially predicting onset, improvement, and stability...
Prevalence and age of onset for drug use in seven international sites: results from the international consortium of psychiatric epidemiologyWilliam A Vega
Institute for Quality, Research, and Training, Robert Wood Johnson Medical School UMDNJ, 335 George Street, 3rd Floor, Liberty Plaza, New Brunswick, NJ 08901, USA
Drug Alcohol Depend 68:285-97. 2002..Methodological limitations of the study along with recommendations for future international comparative research are discussed...
Prevalence, recognition and management of depression in primary care in Germany: the Depression 2000 studyHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy and Technical University of Dresden, Dresden, Germany
Hum Psychopharmacol 17:S1-11. 2002..It remains of continued prime importance to educate primary care doctors to better recognise depression in order to increase the patients' chances of receiving appropriate treatment...
Patterns of incidence and psychiatric risk factors for traumatic eventsMurray B Stein
Department of Psychiatry, University of California San Diego, La Jolla, CA 92037, USA
Int J Methods Psychiatr Res 11:143-53. 2002..The mechanisms by which premorbid psychiatric disorders promote exposure to traumatic events are unknown. Better understanding of these pathways may lead to novel strategies for primary and secondary prevention of PTSD...
Generalized anxiety disorder: comorbidity, comparative biology and treatmentDavid J Nutt
School of Medical Sciences, University of Bristol, UK
Int J Neuropsychopharmacol 5:315-25. 2002..Finally, current pharmacological and non-pharmacological treatment options for GAD are reviewed, with particular attention being paid to published clinical-trial data...
The prevalence of treated and untreated mental disorders in five countriesRob V Bijl
Department of Crime Prevention and Sanctions, Research and Documentation Center, Ministry of Justice, The Netherlands
Health Aff (Millwood) 22:122-33. 2003..Undertreatment of serious cases is most pronounced among young poorly educated males. Outreach is needed to reduce barriers to care among serious cases and young people at risk of serious disorders...
The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) SurveysLaura Andrade
Institute and Department of Psychiatry, School of Medicine, , Brazil
Int J Methods Psychiatr Res 12:3-21. 2003....
Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlledPeter Bramlage
Institute of Clinical Pharmacology, Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden
Am J Hypertens 17:904-10. 2004..The objective of this study was to assess the prevalence of hypertension and the diagnosis, treatment status, and control rates of hypertension in obese patients as compared to patients with normal weight...
Risk factors for premenstrual dysphoric disorder in a community sample of young women: the role of traumatic events and posttraumatic stress disorderAxel Perkonigg
Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
J Clin Psychiatry 65:1314-22. 2004..CONCLUSIONS: Traumatic events and pre-existing anxiety disorders are risk factors for the development of PMDD. The underlying mechanisms are unknown, making further investigation necessary...
The accuracy of prevalence estimations for suicide attempts. how reliably do adolescents and young adults report their suicide attempts?Bettina Christl
Dresden University of Technology, Clinical Psychology and Psychotherapy
Arch Suicide Res 10:253-63. 2006..One-third of all baseline suicide attempters did not report their suicide attempt again at the four years later assessment. In particular, 80% of all nonreporters were female, and almost 60% were aged 14-17 at baseline...
[Prevalence, drug treatment and metabolic control of diabetes mellitus in primary care]David Pittrow
Institut fur Klinische Pharmakologie, Forschungsverbund Public Health, Technische Universitat Dresden, Dresden, Germany
Med Klin (Munich) 101:635-44. 2006....
Substance use and substance use disorders in a community sample of adolescents and young adults: incidence, age effects and patterns of useAxel Perkonigg
Department of Clinical Psychology and Psychotherapy, Dresden University of Technology, Dresden, Germany
Eur Addict Res 12:187-96. 2006..Patterns of onset, cohort trends, and use of various substance classes are also analyzed...
Broadening the definition of generalized anxiety disorder: effects on prevalence and associations with other disorders in the National Comorbidity Survey ReplicationAyelet Meron Ruscio
Department of Health Care Policy, Harvard Medical School, USA
J Anxiety Disord 21:662-76. 2007..Further research is needed to determine whether broadening the current diagnostic criteria results in a more valid characterization of GAD...
Childhood separation anxiety and the risk of subsequent psychopathology: Results from a community studyTanja M Brückl
Department of Clinical Psychology and Epidemiology, Max Planck Institute of Psychiatry, Munich, Germany
Psychother Psychosom 76:47-56. 2007..To examine the association between separation anxiety disorder (SAD) and mental disorders in a community sample and to evaluate whether separation anxiety is specifically related to panic disorder with and without agoraphobia...
Physical activity and prevalence and incidence of mental disorders in adolescents and young adultsAndreas Strohle
Charite Universitatsmedizin Berlin, Campus Charite Mitte, Department of Psychiatry and Psychotherapy, Berlin, Germany
Psychol Med 37:1657-66. 2007..Although positive effects of physical activity on mental health indicators have been reported, the relationship between physical activity and the development of specific mental disorders is unclear...
Supplementary dimensional assessment in anxiety disordersM Katherine Shear
School of Social Work, Columbia University, New York, USA
Int J Methods Psychiatr Res 16:S52-64. 2007..We also suggest that a staging approach to illness, based upon supplementary dimensional rating could provide useful information for clinical and research purposes...
International Day for the Evaluation of Abdominal Obesity (IDEA): a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countriesBeverley Balkau
INSERM U780 IFR69, Research in Epidemiology and Biostatistics, 16 Ave Paul Vaillant Couturier, 94807 Villejuif, France
Circulation 116:1942-51. 2007....
Where have they been? Service use of regular substance users with and without abuse and dependenceAxel Perkonigg
Technische Universitat Dresden, Dresden, Germany
Soc Psychiatry Psychiatr Epidemiol 41:470-9. 2006..To present lifetime rates of service use for psychological and substance use related problems among regular substance users and to examine factors associated with service use...
Evidence that the outcome of developmental expression of psychosis is worse for adolescents growing up in an urban environmentJanneke Spauwen
Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
Psychol Med 36:407-15. 2006..The environment may impact on risk for psychotic disorder by causing an abnormal persistence of a developmentally common expression of psychotic experiences...
How prevalent is smoking and nicotine dependence in primary care in Germany?Eva Hoch
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Munich, Germany
Addiction 99:1586-98. 2004....
Cost of disorders of the brain in EuropePatrik Andlin-Sobocki
Stockholm Health Economics, Stockholm, Sweden
Eur J Neurol 12:1-27. 2005
Pathways into ecstasy use: the role of prior cannabis use and ecstasy availabilityPetra Zimmermann
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstrasse 2, 80804 Munich, Germany
Drug Alcohol Depend 79:331-41. 2005..To explore the role of cannabis use for the availability of ecstasy as a potential pathway to subsequent first ecstasy use...
Towards a better understanding of the size and burden and cost of brain disorders in EuropeHans-Ulrich Wittchen
Eur Neuropsychopharmacol 15:355-6. 2005
Longitudinal course of posttraumatic stress disorder and posttraumatic stress disorder symptoms in a community sample of adolescents and young adultsAxel Perkonigg
Clinical Psychology and Epidemiology Department, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
Am J Psychiatry 162:1320-7. 2005..The authors examined determinants of remission and chronicity of PTSD and associations with other disorders in a prospective community sample...
Rethinking the duration requirement for generalized anxiety disorder: evidence from the National Comorbidity Survey ReplicationRonald C Kessler
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
Psychol Med 35:1073-82. 2005....
Dependence symptoms in young cannabis users? A prospective epidemiological studyAgnes Nocon
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstrasse 2 10, 80804 Munich, Germany
J Psychiatr Res 40:394-403. 2006..To examine prospectively over a period of 4 years the profile of cannabis dependence and the risk of specific dependence criteria in a community sample of adolescents...
Should excessive worry be required for a diagnosis of generalized anxiety disorder? Results from the US National Comorbidity Survey ReplicationAyelet Meron Ruscio
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
Psychol Med 35:1761-72. 2005..No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD...
Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community studyRoselind Lieb
Clinical Psychology and Epidemiology Unit, Max Planck Institute of Psychiatry, Kraepelinstr 2, 80804 Munich, Germany
Arch Gen Psychiatry 59:365-74. 2002..This article examines associations between DSM-IV depressive disorders, their natural course, other psychopathology, and parental major depression in a community sample of adolescents and young adults...
