Marcus J Wirth

Summary

Country: Germany

Publications

  1. ncbi request reprint Biolistic transfection of organotypic cultures of rat visual cortex using a handheld device
    Marcus J Wirth
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 56a, D 44780, Bochum, Germany
    J Neurosci Methods 125:45-54. 2003
  2. ncbi request reprint Accelerated dendritic development of rat cortical pyramidal cells and interneurons after biolistic transfection with BDNF and NT4/5
    Marcus J Wirth
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 56a, D 44780 Bochum, Germany
    Development 130:5827-38. 2003
  3. ncbi request reprint Parvalbumin expression in visual cortical interneurons depends on neuronal activity and TrkB ligands during an Early period of postnatal development
    Silke Patz
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 72, D 44780 Bochum, Germany
    Cereb Cortex 14:342-51. 2004
  4. ncbi request reprint Neuronal activity and neurotrophic factors regulate GAD-65/67 mRNA and protein expression in organotypic cultures of rat visual cortex
    Silke Patz
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, ND 6 72, Ruhr Universitat, 44780 Bochum, Germany
    Eur J Neurosci 18:1-12. 2003
  5. pmc Transcellular induction of neuropeptide Y expression by NT4 and BDNF
    Marcus J Wirth
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 72, D 44780 Bochum, Germany
    Proc Natl Acad Sci U S A 102:3064-9. 2005
  6. doi request reprint Identification of auditory neurons by retrograde labelling for patch-clamp recordings in a mixed culture of chick brainstem
    Marcus J Wirth
    Institute of Biology II, RWTH Aachen, Kopernikusstrasse 16, D 52074 Aachen, Germany
    J Neurosci Methods 169:55-64. 2008

Detail Information

Publications6

  1. ncbi request reprint Biolistic transfection of organotypic cultures of rat visual cortex using a handheld device
    Marcus J Wirth
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 56a, D 44780, Bochum, Germany
    J Neurosci Methods 125:45-54. 2003
    ..We achieve a high degree of co-expression of independent plasmids coated on the same particles. The expression of the neurotrophin plasmids is demonstrated on mRNA and protein level...
  2. ncbi request reprint Accelerated dendritic development of rat cortical pyramidal cells and interneurons after biolistic transfection with BDNF and NT4/5
    Marcus J Wirth
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 56a, D 44780 Bochum, Germany
    Development 130:5827-38. 2003
    ..The results suggested that early in development BDNF and NT4/5 probably accelerate dendritogenesis in an autocrine fashion. In particular, branch formation was advanced towards the adult pattern in pyramidal cells and interneurons...
  3. ncbi request reprint Parvalbumin expression in visual cortical interneurons depends on neuronal activity and TrkB ligands during an Early period of postnatal development
    Silke Patz
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 72, D 44780 Bochum, Germany
    Cereb Cortex 14:342-51. 2004
    ..Once established, PARV expression became resistant to late-onset activity deprivation. In conclusion, PARV expression depended on activity and TrkB ligands which appear to prime the PARV expression already before its developmental onset...
  4. ncbi request reprint Neuronal activity and neurotrophic factors regulate GAD-65/67 mRNA and protein expression in organotypic cultures of rat visual cortex
    Silke Patz
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, ND 6 72, Ruhr Universitat, 44780 Bochum, Germany
    Eur J Neurosci 18:1-12. 2003
    ..The early presence of neuronal activity promoted the GAD expression in OTC to a neurotrophin-independent state suggesting that neurotrophins play a context-dependent role...
  5. pmc Transcellular induction of neuropeptide Y expression by NT4 and BDNF
    Marcus J Wirth
    AG Entwicklungsneurobiologie, Fakultat fur Biologie, Ruhr Universitat, ND 6 72, D 44780 Bochum, Germany
    Proc Natl Acad Sci U S A 102:3064-9. 2005
    ..The transcellular induction of NPY suggests a source-to-sink model for axonal transport and a local cortical redistribution of TrkB ligands to interneurons competent for NPY expression...
  6. doi request reprint Identification of auditory neurons by retrograde labelling for patch-clamp recordings in a mixed culture of chick brainstem
    Marcus J Wirth
    Institute of Biology II, RWTH Aachen, Kopernikusstrasse 16, D 52074 Aachen, Germany
    J Neurosci Methods 169:55-64. 2008
    ..In the future, this method can be combined with single cell PCR to match nuclear origin, firing patterns and the expression of functional molecules in vitro...